alex math @alexmathalex
ml meets proteins Cambridge, England Joined April 2022-
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Biology’s lack of data is holding back its AI boom. Epoch’s latest report shows explosive growth in biological model training data size from 2017–2021 (9.7×/year), but a (2.1x/year) plateau since. AI models for biology are ready to transform science if the data can keep up.
(1/n) Sampling from the Boltzmann density better than Molecular Dynamics (MD)? It is possible with PITA 🫓 Progressive Inference Time Annealing! A spotlight @genbio_workshop of @icmlconf 2025! PITA learns from "hot," easy-to-explore molecular states 🔥 and then cleverly "cools"…
🚀 After two+ years of intense research, we’re thrilled to introduce Skala — a scalable deep learning density functional that hits chemical accuracy on atomization energies and matches hybrid-level accuracy on main group chemistry — all at the cost of semi-local DFT. ⚛️🔥🧪🧬
Researchers can analyze vast protein datasets faster with MMseqs2-GPU in the MSA-Search NIM. Unlock new possibilities for disease research and therapeutic breakthroughs. #drugdiscovery ➡️ nvda.ws/4kMUoqd
Another great example of the UK's ability to develop unique data to push forward AI for bio infrastructure Props to @Basecamp_Res for launching the world's largest biodiscovery dataset, over 10x the number of protein sequences than are currently publicly available 🧬🚀
Protein structure ≠ protein folding/dynamics The new north star: energy‑landscape learning, rather than static structure prediction Next wave: AI that learns free energy for "true" inverse folding
most underrated fundraising strategy: revenue
🧬 News alert: We’re bringing BaseData out of stealth — the world’s largest and fastest growing biodiscovery dataset, built in collaboration with scientists across 26 countries. 🔍 BaseData adds 9.8 billion newly discovered protein sequences to the known tree of life — expanding…
Exciting work by @Basecamp_Res! Great to see the emphasis on diversity and also the comparison with @tatta_bio's Open MetaGenome (OMG) dataset curated from public databases. I'm super curious - how was the team able to 10x the recovered sequence diversity in the past few months?
Exciting work by @Basecamp_Res! Great to see the emphasis on diversity and also the comparison with @tatta_bio's Open MetaGenome (OMG) dataset curated from public databases. I'm super curious - how was the team able to 10x the recovered sequence diversity in the past few months? https://t.co/D16KgobZbJ
Hot takes, pseudocode, score matching, EBMs and staircases found inside: markneumann.xyz/blog/modeling-…
If you cite Muon, I think you should definitely cite SSD (proceedings.mlr.press/v38/carlson15.…) by @CevherLIONS et al. (sorry I can't find the handle of other authors) -- which proposed spectral descent.
🚨Excited to announce that the Sovereign AI Unit is investing £8m in OpenBind: building the world's largest protein-ligand dataset. Backed by a top UK consortium, inc. Isomorphic Labs and Nobel Laureate David Baker, this will help the UK become the home for AI drug design 1/6🧵
Really pleased to share what I have been working on for 2 months: 🇬🇧 UK SovAI are today announcing our £8m seed investment into OpenBind - A consortium that will actually make AI for drug discovery great by generating 500k experiment protein-ligand complexes!! Explainer 🧵 (1/n)
Really pleased to share what I have been working on for 2 months: 🇬🇧 UK SovAI are today announcing our £8m seed investment into OpenBind - A consortium that will actually make AI for drug discovery great by generating 500k experiment protein-ligand complexes!! Explainer 🧵 (1/n)
🚀 Excited to release BoltzDesign1! ✨ Now with LogMD-based trajectory visualization. 🔗 Demo: rcsb.ai/ff9c2b1ee8 Feedback & collabs welcome! 🙌 🔗: GitHub: github.com/yehlincho/Bolt… 🔗: Colab: colab.research.google.com/github/yehlinc… @sokrypton @MartinPacesa
AGI timelines are very bimodal. It's either by 2030 or bust. AI progress over the last decade has been driven by scaling training compute of frontier systems (3.55x a year, 160x over 4 years). This simply cannot continue beyond this decade, whether you look at chips, power,…
There's an obvious way to fix CVD: removing plaques. There are 2-3 companies doing this. Why so few, given how pervasive CVD is? Lowering LDL is nice but removing plaques periodically seems even better.
i miss gemini-2.5-pro-exp-03-25 so bad :(
The premier conference on Machine Learning for Computational Biology is Sep 9-10 at the NY Genome Center in NYC! Submission deadline is June 1 for 2-page abstracts and 8-page papers (eligible for proceedings track). Registration is now open! (Link below) Please retweet!
We’re now programming energy landscapes, not static folds. Conformational Biasing scans every point mutant 🧬against multiple states in ⏱️<60s on a single 4090—pushing K-Ras ON, tightening Spike-ACE2, rewiring LplA🔧
Brendan Swain @BrendanMSwain
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Romeen Shethx @RomeenSheith
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Jonathan Rayner @JonathanJRayner
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Kristian Frandsen �... @KrFrandsen
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Nathan Miller @nathanmllr
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Martin Mayta @MartinMayta2
215 Followers 574 Following BSc Biotechnology - PhD in Biological Sciences. Teaching assistant professor at @UNRoficial & @UAPArgentina (Argentina)🇦🇷.
Abdul qaim ansar @abdulqaim_ansar
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Ashton C Trotman-Gran... @ATrotmanGrant
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Prashant @DeepBioML
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Manjit Rana 🇮🇳�... @MR_ManjitRana
598 Followers 1K Following Receptor topology, functionality & evolvability @BruningLab @UniOfAdelaide| MS Med.Gen. @UofGlasgow| Proj Assoc @AIC_CCMB| BDS (H.P. uni)| Fmr Dental Surgeon
CUI LUN🇫🇷🇨�... @omnicui
448 Followers 3K Following Synthetic biology | CRISPR | Institut Pasteur | Adelaide University | SJTU | Professor in Changzhou University
GAMA Miguel Angel �... @miangoar
2K Followers 1K Following Biologist that navigates in the oceans of diversity through the space-time | MSc in Biochem/Bioinfo @ibt_unam 🇲🇽 | Protein evo, metagenomics & AI/ML/DL
Nikil @bionikil
62 Followers 842 Following Just a guy loving the art of biomolecules https://t.co/rLc0lnTMd6
hadeel hosseny @HossenyHadeel
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Bebeto @Bebetou60702079
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Ching-Shin Huang @chingshinhuang
85 Followers 707 Following Structural biologist. Open science supporter. Opinions are my own.
Mayur Shirude @MayurShirude3
50 Followers 329 Following Phd student @ RGCB Trivandrum. Exploring epigenetic regulation of hematopoiesis and leukemogenesis. A traveller, 🇮🇳
MasooTiii @Masoud_Kalantar
5 Followers 429 Following PhD at UNR - student in manipulating proteins to make a better world 😅
Rafeeque Mavoor @rafeequemavoor
4K Followers 639 Following 🎨Scientific Illustrator Helping researchers learn scientific illustration through live workshops. 🎓 Founder @scidartacademy
Earaietvu @Earaietvu8814
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Yann Vander Meersche @yann_vander
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Lucas Chae 🌳 @lucas_chae
4K Followers 825 Following iso audience wow fit 🐶https://t.co/c048Y0A0zv other apps 🎯https://t.co/N5aLfEddMJ ⏱️https://t.co/RwTKGKV6jt ADHD Focus 🔔https://t.co/TiPhR0bCPS ADHD Todo 🏳️🌈
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Luessee @Luessee6Hj
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Tewcla @TewclawiXD
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Smisha @Smisha34Ln
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Edward Francisco Mend... @otalvaro_17
239 Followers 1K Following PhD student @uniGoettingen @mpi_nat @CompBioPhys 🇨🇴🫓🏳️🌈🥑
Madson Aragão @madsondeluna
391 Followers 492 Following PhD Student in Bioinformatics. Interested in Machine Learning, Genetics and Protein Design. All opinions/views are my own. #FirstGen 🧬
Sawsueski @SawsueskiG5264
59 Followers 1K Following
Soojung Yang @SoojungYang2
925 Followers 901 Following Molecular simulations and AI for proteins! PhD student @ MIT @RGBLabMIT / website: https://t.co/xHAeCEclfm
David Johnson 🟢 @DavidJohns836tt
56 Followers 784 Following I'm Dave Johnson, Powerball winner of $298.3 million! Giving away $30,000 to every individual who is ready to claim. § Follow me now!
ASI @duskUK
4 Followers 81 Following We're a new deep tech startup, currently in funding negotiations.
Matt Burgess @MattBurgessFSP
16 Followers 123 Following ML Talent Acquisition Lead - Flagship Pioneering @Flagshippioneer is a venture creation engine focusing on building exceptional AI companies
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4K Followers 825 Following iso audience wow fit 🐶https://t.co/c048Y0A0zv other apps 🎯https://t.co/N5aLfEddMJ ⏱️https://t.co/RwTKGKV6jt ADHD Focus 🔔https://t.co/TiPhR0bCPS ADHD Todo 🏳️🌈
Kyle Tretina, Ph.D. @AllThingsApx
4K Followers 471 Following Follow for AI in Digital Biology and Drug Discovery @NVIDIA, ex Insilico Medicine, ex Yale, PhD UMaryland, views are mine, DM for collabs
Mark Neumann @MarkNeumannnn
3K Followers 2K Following Head of ML at Orbital Materials. BC: Research/Eng at @allenai_org
Rafeeque Mavoor @rafeequemavoor
4K Followers 639 Following 🎨Scientific Illustrator Helping researchers learn scientific illustration through live workshops. 🎓 Founder @scidartacademy
JCIM & JCTC Journals @JCIM_JCTC
10K Followers 980 Following Tweets from Journal of Chemical Information and Modeling (JCIM) and Journal of Chemical Theory and Computation (JCTC) from @ACSPublications
Ruiyu Wang (王瑞雨... @ruiyuwangmd
176 Followers 291 Following Postdoc researcher. @tiwarylab University of Maryland, College Park. PhD, Dr. Eric Borguet (@TUChemBot), Dr. Carnevale (@carnevalelab)
clem 🤗 @ClementDelangue
156K Followers 5K Following Co-founder & CEO @HuggingFace 🤗, the open and collaborative platform for AI builders
Thomas Wolf @Thom_Wolf
96K Followers 6K Following Co-founder at @HuggingFace - open-source and open-science
Olexandr Isayev 🇺�... @olexandr
10K Followers 4K Following #CompChem Prof @CMU_Chem. Connecting chemical sciences with AI & #MachineLearning. #tarheels fan. Care:#design, #photography #Ukraine #cats🐈 Rants are mine
Madson Aragão @madsondeluna
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Retro Biosciences @RetroBio_
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Logan Kilpatrick @OfficialLoganK
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Jason Kelly @jrkelly
29K Followers 2K Following Co-founder and CEO at Ginkgo Bioworks ($DNA)🧬 Former Chair of US National Security Commission on Emerging Biotechnology 🇺🇸
José Luis Ricón Fer... @ArtirKel
22K Followers 1K Following Head of Theory at @RetroBio_ , enjoyer of things, blog: https://t.co/8xDYgWAJHB
Marlene Wind @MwiWind
11K Followers 3K Following Prof. European politics and law at @uni_copenhagen 🇪🇺 Special Advisor to HR/VP | @EUI_EU alumni | Columnist at @Berlingske | Personal account
Ben Chamberlain @DrBPChamberlain
2K Followers 793 Following Building foundational models of science @EITOxford https://t.co/qukbizP2Yn 🎓 https://t.co/Ln7xZeV3OA
Lykke Friis @lykkefriis
56K Followers 5K Following Director @thinkeuropa; @ecfr co-chair; board of @teamdanmark Fm. 🇩🇰minister of climate, energy and gender equality #miasanmia🇩🇪
Jennifer Lin @Jlindig0
2K Followers 762 Following Curing rare diseases using science and market dislocation. CEO @ AUG Tx (P3 in ultra-rare). @thielfellowship
The Align Foundation @Align_Bio
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Simona Cristea @simocristea
9K Followers 500 Following cancer genomics AI scientist; head of Data Science & AI and group leader @DanaFarber_Hale; research scientist @Harvard; phd @eth.🇷🇴🇸🇪🇨🇭🇺🇸
Ali Madani @thisismadani
7K Followers 1K Following Founder & CEO of Profluent (https://t.co/GpoVdKW1zQ, we're hiring!). AI+Biology to cure disease. Berkeley PhD. formerly Research @ Salesforce AI.
Biology+AI Daily @BiologyAIDaily
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66K Followers 882 Following Group Partner at @ycombinator Cofounded @gocardless and @monzo
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Yunha Hwang @Micro_Yunha
4K Followers 1K Following Building genomic intelligence, Asst Prof @MITBiology, @MITEECS, @MIT_SCC, Chief Scientist @tatta_bio https://t.co/gF8HeJo5hU
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Kresten Lindorff-Lars... @LindorffLarsen
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Hyung Won Chung @hwchung27
38K Followers 301 Following AI Research Scientist @Meta Superintelligence Labs. Past: @OpenAI / @Google Brain / PhD @MIT
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861 Followers 1K Following I build systems for revolutionaries. @seldonai, @apartresearch, Juniper, ENAIS, AISA.
Patrick Kidger @PatrickKidger
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Amy Lu @amyxlu
4K Followers 2K Following Senior Research Scientist @IsomorphicLabs building AI for drug discovery. CS PhD @berkeley_ai. Prev: @PrescientDesign @insitro @UofT 🇨🇦
Corin Wagen @CorinWagen
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