@markandermann.bsky.social @andermann_mark
Neuroscientist. Canadian. andermannlab.com Joined June 2018-
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NEW: Mark Andermann (@andermann_mark) of @harvardmed and @BIDMChealth brings experimental data and computational modeling together to understand cortical reactivations. Watch the video: youtu.be/1N6i7Zi9kXs #NeuroAI2025 #neuroscience #AI #NeuroAI
We previously showed that specific hypothalamic neurons get more and more activated by each bite of food until they put a brake on homeostatic feeding. Here, we find that this brake is already on at the start of a meal in obese mice on a high-fat diet. Nice work, Marta & team!
We previously showed that specific hypothalamic neurons get more and more activated by each bite of food until they put a brake on homeostatic feeding. Here, we find that this brake is already on at the start of a meal in obese mice on a high-fat diet. Nice work, Marta & team! https://t.co/flhcjEsvdz
A drop of milkshake takes a wild ride after it is swallowed. Rachel and Kiersten came up with cool strategies for visualizing food passing through the mouse GI tract and mapping the activity of the same 100s of brainstem neurons across weeks during feeding and other behaviors.
A drop of milkshake takes a wild ride after it is swallowed. Rachel and Kiersten came up with cool strategies for visualizing food passing through the mouse GI tract and mapping the activity of the same 100s of brainstem neurons across weeks during feeding and other behaviors. https://t.co/NsktERUlNr
I’m so excited to share our preprint on how brainstem neurons sense and integrate multiple body signals during food consumption. We imaged 1000s of neurons across the lateral parabrachial nucleus (LPBN) in behaving mice. biorxiv.org/content/10.110…
[1/4] Registration for our two-day virtual & in-person symposium in June is now open! See below for the full list of cutting-edge experts in #neuroscience and #AI speakers:
Stand Up for Science rally, March 7, 12-4 pm, Boston Common. Better than moping. eventbrite.com/e/stand-up-for…
We lack tools to track >1-2 changing signals in brain fluids. Peter Kalugin and an amazing team begin to address this challenge with simultaneous, real-time tracking of many (10+) neuromodulatory signals using Multiplexed Optical Recording of Sensors on a micro-Endoscope (MORSE).
We lack tools to track >1-2 changing signals in brain fluids. Peter Kalugin and an amazing team begin to address this challenge with simultaneous, real-time tracking of many (10+) neuromodulatory signals using Multiplexed Optical Recording of Sensors on a micro-Endoscope (MORSE).
I am thrilled and grateful to share that I’ll be starting my lab at @ISTAustria in June 2025! We will study how the hypothalamus maintains homeostasis in response to challenges. Check out our website: dmhlab.org, and if interested please get in touch!
In other words, perhaps we should consider slowing down and savoring each moment.
In other words, perhaps we should consider slowing down and savoring each moment. https://t.co/n4T1PXKWSu
I am thrilled to share the published version of our study on how neuropeptide signals regulate feeding in the hypothalamus! We imaged endogenous peptide signals in subcellular compartments during behavior. Below is an updated summary: rdcu.be/dZlI3
We found that in vivo peptide release and signaling gradually enhances the response of satiety-promoting hypothalamic neurons to each bite of food during a meal. These consequences of each bite take minutes to manifest, and could help explain why slow eating enhances satiety.
We found that in vivo peptide release and signaling gradually enhances the response of satiety-promoting hypothalamic neurons to each bite of food during a meal. These consequences of each bite take minutes to manifest, and could help explain why slow eating enhances satiety.
Pretty exciting result: disrupting cue reactivations in mouse visual cortex in the hours *after* operant training completely blocks learning.
Our perspective on the frontiers of neuroscience beyond the nervous system. Thank you, @CellCellPress, for the opportunity to collaborate with our partners @NadineGogolla and @SLiberles. Thanks Chi Jingyi and Popescu, Miranda. My special thanks to Megan Sammons.
Our perspective on the frontiers of neuroscience beyond the nervous system. Thank you, @CellCellPress, for the opportunity to collaborate with our partners @NadineGogolla and @SLiberles. Thanks Chi Jingyi and Popescu, Miranda. My special thanks to Megan Sammons.
Out in @CellCellPress now with added data and analysis! @Huixin_BJ and colleagues report that the choroid plexus has specialized epithelial-immune synergy that modulates epithelial barrier plasticity during brain inflammation. authors.elsevier.com/sd/article/S00…
What questions should we be asking as neuroscientists, and how should we go about answering them in satisfying and innovative ways? I think that seeking training in Stephen Zhang's nascent lab @NYU_CNS is a great way to find answers to these questions in an amazing environment.
What questions should we be asking as neuroscientists, and how should we go about answering them in satisfying and innovative ways? I think that seeking training in Stephen Zhang's nascent lab @NYU_CNS is a great way to find answers to these questions in an amazing environment.
Stress can trigger willful seeking of a starvation-like state in certain female mice predisposed to higher anxiety. Now published and downloadable here: authors.elsevier.com/a/1iyP-3BtfH9A… Congrats to lead-author @haganK, @Oren_Amsalem, @andrewlutas, and the whole team. Feedback welcome!
Stress can trigger willful seeking of a starvation-like state in certain female mice predisposed to higher anxiety. Now published and downloadable here: authors.elsevier.com/a/1iyP-3BtfH9A… Congrats to lead-author @haganK, @Oren_Amsalem, @andrewlutas, and the whole team. Feedback welcome!
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