Naphak Modhiran @cusycon
postdoc virologist @UQ : believes in imagination-💡 -traveller : loves nature 🏔🗻🏝🏖🛩📷 Joined March 2007-
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Naphak Modhiran retweeted
"A single plasmid encodes TrmA fused to a protein of interest, covalently linking the variant proteins to RNA barcodes in vivo. The barcoded fusion proteins are utilized for epitope binding, protease cleavage, and solubility, with activity measured by DNA sequencing read counts."
"A single plasmid encodes TrmA fused to a protein of interest, covalently linking the variant proteins to RNA barcodes in vivo. The barcoded fusion proteins are utilized for epitope binding, protease cleavage, and solubility, with activity measured by DNA sequencing read counts." https://t.co/a9QR7NVCgg
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Naphak Modhiran retweeted
Our new study is out at @CellReports! We used 53 sarbecovirus pseudoviruses and 17 ACE2 expressing cells and demonstrated that 4 residues in spike contribute to the expansion of ACE2 usage range. Congrats Yusuke🎊! cell.com/cell-reports/f…
Naphak Modhiran retweeted
1206 genomes reveal origin and movement of Aedes aegypti driving increased dengue risk | Science science.org/doi/10.1126/sc…
Naphak Modhiran retweeted
Dengue virus infection reprograms baseline innate immune gene expression: Med cell.com/med/fulltext/S…
Naphak Modhiran retweeted
One of the most important questions in the longevity field is whether an aged environment will wear out young cells, or if young cells will de-age an old environment. Incredibly important paper below pointing to the former!
One of the most important questions in the longevity field is whether an aged environment will wear out young cells, or if young cells will de-age an old environment. Incredibly important paper below pointing to the former!
Naphak Modhiran retweeted
RFdiffusion2 is now on Github under the RosettaCommons umbrella. Developers from the IPD are working with the Rosetta Commons Devel Team to get the inference code up and running in its new home. github.com/RosettaCommons… Nice!
Naphak Modhiran retweeted
De novo design of light-responsive protein–protein interactions enables reversible formation of protein assemblies ift.tt/rc5lnRI
Naphak Modhiran retweeted
Nature research paper: One-shot design of functional protein binders with BindCraft go.nature.com/4g0R09u
Naphak Modhiran retweeted
🔍 Look the statistics in #France regarding to #mosquito borne #arboviruses notified by the end of Aug‼️ 🦠 228 #Chikungunya cases 🦠 15 #Dengue cases 🦠 15 #WestNile human infections 🦟 #VectorControl interventions are key to reduce risks of transmission ✔️
Naphak Modhiran retweeted
Here's how to predict binding of tens or hundreds of small molecules to protein assemblies using Boltz 2 in ChimeraX. Accuracy depends on how similar the ligands and binding pockets are to existing experimental structures. rbvi.ucsf.edu/chimerax/data/…
Naphak Modhiran retweeted
Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, @csche11h, @sokrypton, @befcorreia and many other amazing lab members and collaborators. nature.com/articles/s4158…
Naphak Modhiran retweeted
Identification of broadly inhibitory anti-PfEMP1 antibodies by mass spectrometry sequencing of plasma IgG from a malaria-exposed child pnas.org/doi/abs/10.107…
Naphak Modhiran retweeted
A new #ScienceReview looks at a different approach to drug discovery that may enable drugging of unconventional targets through stabilization of macromolecular complexes with molecules known as “LOCKTACs.” Learn more: scim.ag/4lAiKmF
Naphak Modhiran retweeted
Did you know amphibians and fish have viruses that are very similar to human influenza B viruses? We didn't know either, but Eddie Holmes found them and we had a closer look at their HAs and NAs. with @gabagagan @WardLab1 @RobertPdeVries1 @dishabhavsar science.org/doi/10.1126/sc…
Naphak Modhiran retweeted
Another new paper from our lab - this time from Anastasiya Kishkevich who has developed "YTK Display-and-Secrete" a library-based method to identifying genetic designs good for protein secretion from S.cerevisiae yeast. Online now at ACS SynBio - pubs.acs.org/doi/10.1021/ac…
Naphak Modhiran retweeted
Master’s student Kenya Lugo researches antigenicity of Ross River virus, w/ aims to find cross-reactive antibodies b/w wild type & chimeric virus strains. Rising outbreaks & no licensed vaccine, her work is crucial for future therapeutic developments. @JodyPeters20
Naphak Modhiran retweeted
🦠 New tool alert! Scientists developed NASPA, a rapid assay to profile antibodies that block influenza’s neuraminidase – helping track antigenic drift & guide better vaccine design. Faster, simpler, and HA-antibody–independent! 💉🔬 👉 doi.org/10.1038/s41541… #Flu #Vaccines #NA
Naphak Modhiran retweeted
ProteinGenerator simultaneously generates protein sequences and structures using sequence space diffusion go.nature.com/4gGcus0 rdcu.be/eBetI
Naphak Modhiran retweeted
Happy to share the final version of our article on the identification and characterization of novel bat coronaviruses, published in @PLOSPathogens 🦇🎉 Congrats to Claudia, first author of this paper, and all co-authors! 👏 dx.plos.org/10.1371/journa…
Naphak Modhiran retweeted
The @UWproteindesign's experimental pipeline behind models like RFdiffusion and ProteinMPNN: - A rapid, scalable, pipeline for producing and characterizing proteins - A demultiplexing protocol for converting oligopools to clonal constructs Jason Qian @LFMilles @BasileWicky
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Antiverse @AntiverseHQ
238 Followers 331 Following Designing functional antibodies for the most challenging targets. 📍Cardiff, Wales 👩🔬 https://t.co/MVuIMNBGYz
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LingOrm_OnMineWay @LingOrm_OnMineW
22K Followers 65 Following SupportLingOrm 💜🦮🍳 ... Know more , no sis. ((อยากใส่ใจแบบใกล้ซิส)) 👀🤏
LingOrm_BaseHouse @LingOrm_BH
100K Followers 50 Following บ้านแฟนคลับหลักของหลิงออม 𝐒𝐔𝐏𝐏𝐎𝐑𝐓 “𝐋𝐈𝐍𝐆𝐋𝐈𝐍𝐆 𝐊𝐖𝐎𝐍𝐆” @linglingsirilak “𝐎𝐑𝐌 𝐊𝐎𝐑𝐍𝐍𝐀𝐏𝐇𝐀𝐓” @ormmormm #หลิงออม #LingOrm 💜🦮🪽🦋
Lukas Valihrach @LukasValihrach
3K Followers 729 Following Group Leader | GliaOmics Lab & GeneCore Facility | 🧬Single-Cell & Spatial Transcriptomics | 🧠 Glial Cells in Health & Disease | @IBT_CAS 🇪🇺 | ❤️ My Twins
Orm Kornnaphat Offici... @ormkornnp_ofc
56K Followers 30 Following CLOSED : Official fanbase for Orm Kornnaphat ✨ บ้านแฟนคลับหลักของ ออม กรณ์นภัส ✨@ormmormm #ormkornnaphat #ออมกรณ์นภัส #ไข่เจียวของออมเล็ต
NIAID-CREID @CREID_Network
601 Followers 0 Following The Centers for Research in Emerging Infectious Diseases Network, funded by NIH/NIAID, is comprised of 10 Research Centers and a Coordinating Center.
orm kornnaphat🌈 @ormmormm
414K Followers 64 Following ♡#ออมกรณ์นภัส #OrmKornnaphat #ไข่เจียวของออมเล็ต
Yellow4FLAVI @yellow4... @yellow4flavi
37 Followers 57 Following Deconstructing the protective immunity of yellow fever virus 17D to inform flavivirus vaccine design. Horizon Europe funded project,13 partners from 7 countries
Climate Amplified Dis... @climade_health
144 Followers 130 Following A global consortium led by the global south to study and respond to Climate Amplified Diseases and Epidemics
Varun Shanker @varunrshanker
641 Followers 403 Following @StanfordMed MD-PhD Program | Caltech '21 @caltechmten
Robert Haase @haesleinhuepf
12K Followers 4K Following #GenerativeAI, LLMs, (Image) Data Analysis, GPUs @Sca_DS / @UniLeipzig, also @NFDI4BioImage, @NEUBIAS_, @GloBIAS_ #openscience, views:mineTrends for United States
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