Gene Regulation @generegulation
Gene regulation news, events and opinions. #chromatin #nucleosome #TFbinding #CTCF #cancer #epigenetics #openscience. Also @[email protected] generegulation.org London, UK Joined January 2013-
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Great collaboration with @DrZoeWaller and Dr Ke Li in Exeter! Hope it will benefit the community 😊 iM-Seeker: a webserver for DNA i-motifs prediction and scoring via automated machine learning academic.oup.com/nar/article/do…
A great opportunity available for bioinformatics scientists to explore epigenetics in our lab. @MCRCnews @FBMH_UoM @MCF_UoM @MCRBreastCentre jobs.manchester.ac.uk/Job/JobDetail?…
Join us for your #PhD or #MDPhD if you are interested in exploring how networks of transcription factors & chromatin modifiers can time development by generating transcriptional oscillations. Apply here 👇
Excited to finally share my work with @charlesdanko on the regulatory syntax governing transcription initiation and training genomic DL models on diverse genomes. doi.org/10.1101/2024.0…. Blurb thread below: 0/8
Glad that our sequence model of promoters in human genome is now published in @ScienceMagazine. Check out the paper for a deep dive into the sequence basis of transcription initiation at the basepair level: science.org/doi/10.1126/sc…
Seeking someone looking for a two-year postbac position to get my group up and running at Yale University! We will be utilizing chromatin tracing and other multiplexed imaging approaches to study the relationship between 3D genome organization and epigenetic memory in embryos!
(1/n) excited to share that our study on how condensate-promoting ENL mutations drive tumorigenesis is out at @CD_AACR! aacrjournals.org/cancerdiscover…
"caQTLs and haQTLs capture regulatory variations not associated with eQTLs and explain ∼49% of the functionally annotated GWAS loci" Been clear for a while that accessibility & histone marks provide more info for explaining & fine mapping GWAS loci than expression. 1/
"caQTLs and haQTLs capture regulatory variations not associated with eQTLs and explain ∼49% of the functionally annotated GWAS loci" Been clear for a while that accessibility & histone marks provide more info for explaining & fine mapping GWAS loci than expression. 1/
Great opportunities with exciting projects in my lab!
Great opportunities with exciting projects in my lab!
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s4158…. Thread ⬇️⬇️⬇️ (1/8)
🚨Transcription and Chromatin UK is back for 2024🚨 We will be in Newcastle from 25th to 27 Sept. Register your interest so you're the first to know when registration opens 🧬 biochemistry.org/events-and-tra…
We are looking for a PhD candidate to work on the "histone code hypothesis" using epigenetic rewriting techniques. Deadline 12th of May. adum.fr/as/ed/voirprop… @rkoszul @pablonavarroLAB @G__Fischer @maxvcg @djost_physbiol @GAlmouzni @alphatauri2011 @leonidmirny
Preprint alert! 🎉I am excited to share the work from our enjoyable collaboration with @wendy_bickmore @josh_brickman labs. Investigating the role of PRC2 in stabilising the developmental transcriptional response during endodermal differentiation. doi.org/10.1101/2024.0…
Do you like #ChIPseq & #CUTnRUN as much as we do? Join the #PALSSummerSchool2024 and learn 🎨The Art of Peak Calling ⛰️ (#biochemistry and #bioinformatics) by @AnnaNordin96 the #CUTnRUN Master from @liu_universitet @WCMM_at_LiU REGISTER > trippus.net/summerschool
Do you like #ChIPseq & #CUTnRUN as much as we do? Join the #PALSSummerSchool2024 and learn 🎨The Art of Peak Calling ⛰️ (#biochemistry and #bioinformatics) by @AnnaNordin96 the #CUTnRUN Master from @liu_universitet @WCMM_at_LiU REGISTER > trippus.net/summerschool
📣 we’re excited to see all the fantastic abstracts coming in, if you haven’t submitted yet then you have until midnight BST tomorrow!👨💻🧑💻👩💻 There are prizes to be won 🤓 Register for the symposium: register.oxfordabstracts.com/event/51330?pr… Submit your abstract: auth.oxfordabstracts.com/?redirect=/sta…
Come join us in Oxford as an Associate Professor in Molecular and Cellular Biochemistry. We are considering a wide range of research areas, but I would note that we have a vibrant chromatin and gene regulation community. Happy to answer questions if you are interested. Please RT!
📢 Pioneer and repressing transcription factors regulate nucleus-wide chromatin motions and architecture - check out our work led by @h_shaban pnas.org/doi/epdf/10.10… - more details 👇
📢 Pioneer and repressing transcription factors regulate nucleus-wide chromatin motions and architecture - check out our work led by @h_shaban pnas.org/doi/epdf/10.10… - more details 👇
Most Hi-C experiments report a population average of interactions. #SingleCell Hi-C shows that bona fide #Enhancer-Promoter interaction hubs do form as #ESCells exit naive pluripotency...but the promoter interacts with different enhancers in different cells. Read all about it:
Most Hi-C experiments report a population average of interactions. #SingleCell Hi-C shows that bona fide #Enhancer-Promoter interaction hubs do form as #ESCells exit naive pluripotency...but the promoter interacts with different enhancers in different cells. Read all about it:
Join us for an exciting opportunity to foster lab-in-the-loop approaches for causal discovery. #Heidelberg
Join us for an exciting opportunity to foster lab-in-the-loop approaches for causal discovery. #Heidelberg
See a cool chart on a paper? Just copy the image to GPT-4 and ask for code! Here I stole an idea and implemented a new way to visualize GO enrichment in ShinyGO (bioinformatics.sdstate.edu/go/).
Karolin Luger @LugerLab
9K Followers 1K Following (she/her). Chromatin and cryoEM afficionada. Still a fan of crystallography. @Nucleosomepolice on bsky. Here today, blue tomorrow. Opinions are my own.
Anshul Kundaje (anshu.. @anshulkundaje
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Schübeler Lab @SchubelerLab
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Cedric🧬➰🧬Fesc.. @CedricFeschotte
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Nucleosome papers �.. @Nucleosome_Bot
5K Followers 9 Following Publications about nucleosomes. Maintained by @TeifLab. Also see @TF_binding_bot, @CTCF_papers, @cfDNA_papers, @generegulation. @[email protected]
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Nature Genetics @NatureGenet
128K Followers 2K Following Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. RT/like=interesting/relevant, not necessarily endorsement.
Carmelo Ferrai @CarmeloFerrai
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[email protected]... @Roubo3elzain
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Joseph Patria @JNPatria
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Segun Fatumo @SFatumo
4K Followers 941 Following Associate Professor, NCDE, LSHTM, United Kingdom. Associate Professor, MRC/UVRI and LSHTM Uganda. Genomics | GWAS | Africa | Capacity Building | Global Health
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108 Followers 210 Following Postdoctoral Fellow @NCIResearchCtr, @NIH. Tracker of single molecules.
Karthik Viswanathan @Karthik140801
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Chaima BESSAADI @CBessaadi
1 Followers 35 Following
Karolin Luger @LugerLab
9K Followers 1K Following (she/her). Chromatin and cryoEM afficionada. Still a fan of crystallography. @Nucleosomepolice on bsky. Here today, blue tomorrow. Opinions are my own.
Anshul Kundaje (anshu.. @anshulkundaje
22K Followers 2K Following Genomics, Machine Learning, Statistics, Big Data and Football (Soccer, GGMU). Post: @anshulkundaje, Threads: anshulkundaje
Arjun Raj @arjunrajlab
25K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12
Maxim Greenberg @maxvcg
6K Followers 1K Following Group leader @IJMonod. When I say "epigenetics" what I really mean is "DNA methylation".
Schübeler Lab @SchubelerLab
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Wendy Bickmore @wendy_bickmore
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Luca Giorgetti @LucaGiorgetti
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18K Followers 5K Following I'm not on twitter anymore, find my on Bluesky or Mastodon
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3K Followers 1K Following Professor for Translational Epigenetics, University Medical Centre Goettingen, University of Goettingen, DE …oftentimes aspiring fiction writer.
Cedric🧬➰🧬Fesc.. @CedricFeschotte
8K Followers 2K Following Prof @Cornell, #firstgen, immigrant 🇫🇷🇺🇸, he/him. Come for the memes, stay for the transposon and virus stuff.
Nucleosome papers �.. @Nucleosome_Bot
5K Followers 9 Following Publications about nucleosomes. Maintained by @TeifLab. Also see @TF_binding_bot, @CTCF_papers, @cfDNA_papers, @generegulation. @[email protected]
Mitch Guttman @mitchguttman
3K Followers 190 Following Molecular biologist interested in non-coding RNAs, nuclear organization, and gene regulation. Professor at Caltech
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3K Followers 959 Following Epigenetics and transposons. @brancolab.bsky.social
Nature Genetics @NatureGenet
128K Followers 2K Following Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. RT/like=interesting/relevant, not necessarily endorsement.
Geoff Faulkner @Faulkner_Lab
3K Followers 313 Following Professor, University of Queensland. Retrotransposons and genomics. Views my own. Scholar publications: https://t.co/xQu0hWudj1 @faulknerlab.bsky.social
Susanne Bornelöv @sus_bo
156 Followers 128 Following Wellcome Career Development Award fellow @Cambridge_Uni interested in data-driven methods to understand gene regulation and genome organisation
Benjamin Werner @BenjaminWerner_
1K Followers 564 Following Reader in Somatic Evolution @QMBCI. UKRI Future Leader Fellow. What is hidden is beautiful.
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224 Followers 215 Following Group leader at @CRBM_Montpel. I'm interested in how spatial organization of transcription inside the nucleus controls embryo development.
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251 Followers 41 Following Researcher on transposable elements and genome evolution. Happily married to the most patient wife in the world and proud father of two daughters. Hobby artist.
🧬 The Coster Lab �.. @CosterLab
489 Followers 202 Following Dr. Gideon Coster's Genome Replication lab @ICR_London. Studying what happens when DNA becomes its own enemy...
Itamar Harel @ItamarHarel
744 Followers 289 Following Assistant Professor, Genetics @ the Hebrew University, and a dad. Experimental biology of vertebrate aging and related diseases using the killifish model
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König Lab @koenig_lab
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1K Followers 811 Following ‘Whatever you can do or dream you can, begin it. Boldness has genius, power and magic in it’. Prof of Metabolism & Inflammation. Italo-Brit. Opinions my own.
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Ferbeyre Lab @FerbeyreG
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Centre for Chromosome.. @CCB_Galway
39 Followers 88 Following The CCB at the University of Galway hosts a highly collaborative network of researchers investigating topics linked to the biology of genomes!
ExeterGenomes @ExeterGenomes
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Glennis Logsdon @glennis_logsdon
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Simona Giunta @Simona_Giunta
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Segun Fatumo @SFatumo
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The Genetics Society @GenSocUK
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Brooks Lab @TheBrooksLab
833 Followers 65 Following The Brooks Lab @UCSC | Department of Biomolecular Engineering | We study #DNA and #RNA sequencing data to fight #cancer
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Stephen Ågbomson @Xagbomson
474 Followers 831 Following Scientist | Heterochromatin 🧬🤫~ Structural biologist @nyugrossman| Armache Lab | 🇬🇭
Erika Alden DeBenedic.. @erika_alden_d
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Hasan Yardimci @YardimciLab
332 Followers 207 Following Group leader @TheCrick. Visualising DNA replication machinery one molecule at a time.
William Cross @wchcross
420 Followers 443 Following Researcher in Cancer Genomics, Big Data, and Biomarker discovery. Lecturer in Bioinformatics and Cellular Pathology, University of Westminster
Michael A. Goldman @MAG46XY
417 Followers 484 Following Professor & Former Chair of Department of Biology at SF State; human genetics, evolution. gene expression, personalized medicine
Jennifer Frost @neverlethetruth
256 Followers 551 Following Wellcome Trust CDA funded group leader at King’s College London. Interested in placentas/endosperms, transposons and epigenetics.
Raffaella Nativio @NativioR
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Jean Loup Faulon @jeanloupfaulon
408 Followers 299 Following Research Director @Inra_France Professor @OfficialUoM
Mahdi Moradi Marjaneh.. @DrMahdiMoradi
210 Followers 660 Following Advanced Research Fellow @ImperialInfect @imperialcollege | Bioinformatics scientist with clinical background
Eric Stutheit-Zhao @zhaoEZ
572 Followers 412 Following RadOnc resident @UofTDRO and genomic data scientist. @CancerResearch postdoc at @pmcancercentre. @PMGlobalCancer/@DKFZ Int'l fellow. #MDPhD alum from @UBC.
Enrique Sanz-Garcia @Esanzgarcia
352 Followers 474 Following Medical Oncologist at @pmcancercentre. Assistant Professor at @UoT. Interested in Inmunotherapy, precision medicine and ctDNA in GI and HN tumors.
Emma Louise Robinson,.. @Robinson7L
1K Followers 2K Following Sr. Manager in Scientific Communications at Edwards Lifesciences. Comms Director at AMWA. Woman In Science. 👩⚕️❣️👩💻 #clinicalaffairs #scicomm
Caroline Watson @carolinewatson
1K Followers 779 Following Group Leader @EarlyCancerCam | Research: clonal haematopoiesis, MDS, AML & blood cancer evolution 🩸🔬🧬 | Honorary Consultant Haematologist 🩺 @CUH_NHS
Tigger Tigger burning.. @TiggerBurning
4K Followers 215 Following Тигры все умеют, но ничего не делают, потому что не хотят (с) Но что-то они все же делают, вопреки себе. Молекулярная и клеточная биология - моя профессия.
Ivana Bozic @IBozic_
512 Followers 279 Following Associate prof. of applied math @UW. Using math to understand cancer. Branching process fan.
The Plant Cell @ThePlantCell
35K Followers 1K Following Leading international society-published journal with fast turnaround time, true peer review by top plant scientists, first-class post-acceptance science editing
All I see is a transcription factor searching for its target binding site
Magnetic chaotic pendulum 📹Physicsfun
📢📢Dear friends, I'm thrilled to introduce LiftOn, our new homology-based annotation lift-over tool🚀 Join my talk at @RECOMBseq Saturday April 27th at 2:50PM! @JakobHeinz9 @celinehohzm @alan_mayonnaise @alaina_shumate @elapertea @StevenSalzberg1 🔗github.com/Kuanhao-Chao/L… (1/5)
@BeatrizGerFalc representing @EllisLab_ @CPDR_Labs at #embochromatinbio24 Great job!!!! @PCF_Science @NCIResearchCtr @nciccr_gmb
@RongFan8 providing the perfect final talk at #embochromatinbio24 discussing the use of #singlecell and #spatial analysis in aging and cancer #Epigenetics in Singapore @YaleCancer @nciccr_gmb @CPDR_Labs @YaleBme
Thank you @EMBO for giving me a chance to talk about our work at the Chromatin in Cancer Biology Meeting. #EMBOchromatinBio24 I had a fantastic time and met amazing people. Highly recommend. meetings.embo.org/event/24-chrom…
Happy to share our @NatureComms paper showing that prolonged TFIIH binding to nonexcised DNA damage causes severe neuronal and developmental failure. This can be prevented by depletion of XPA or TTDA, which stabilize TFIIH-DNA binding. nature.com/articles/s4146…
Reversible depletion of Polycomb proteins can induce cancer in the absence of driver mutations @Nature nature.com/articles/s4158…
Broad acting Ras inhibitor that works remarkably well in mouse models of pancreatic cancer developed. This is one of the worst cancers & patients are really keen to enrol in trials. Question: what limits enrolment? I am reminded of @matthewherper 's article for @statnews where…
In the weeks since our work on RAS inhibition was published, we have received many emails and calls from PDAC patients. To educate and disseminate info, I've posted a discussion on our website targeted to lay audience, addressing common patient questions. olivelab.org/ras-inhibitor-…
Opening of exciting Chromatin in Cancer @EMBO workshop by Dennis Kappei + Polly Chen of @csi_singapore. Stephen Baylin opening keynote = super-eloquent overview of this dynamic field. So glad @EMBOPress can be here
#SaveTheDate: We are releasing our DAC Portal v2 on May 23rd🚀! This new version introduces a host of new features designed to streamline your workflow and boost productivity 💪
📢 The abstract and earlybird booking deadline for Translation UK 2024 is next Wednesday! Act now – submit your abstract for the chance to showcase your work and register by 1 May to save money on your registration! ow.ly/TUCU50RlZmk
Save the date: The groundbreaking discovery of the Homeobox genes by Prof. Walter Gehring 40 years ago, will be celebrated with a symposium @biozentrum on October 1st, 2024. Please register here for #Homeobox40: biozentrum.unibas.ch/events/confere…
[WEBINAR] The IUBMB TI (FASBMB region) are having a webinar next week on AI in Biomedical Research, do remember to register if you haven’t!
Full-time Tenure track “Junior Chair” position in any field of research relating to plant mitochondria or chloroplasts @cnrs_ibmp (mitocross.unistra.fr) No citizenship restrictions, no need to speak French. #science #career #jobs #job #jobsearch Deadline: Oct 30. Please RT.
See a cool chart on a paper? Just copy the image to GPT-4 and ask for code! Here I stole an idea and implemented a new way to visualize GO enrichment in ShinyGO (bioinformatics.sdstate.edu/go/).
Post a pic of when you started in academia. This was me about 18 years ago, idealistic and ready to apply for grant proposals!
In order to further the development of an open database of scientific illustrations for the life sciences we have now set up a non-profit under the umbrella of @OC_Europe 1/ opencollective.com/bioicons
Awesome new lab right here 👇 @MobDNAjournal and @CedricFeschotte - add to your respective lists?
Very excited to share news of my @wellcometrust CDA, to work on transposons in pregnancy complications. Hailing from the Medical and Molecular Genetics dept at @KingsCollegeLon, the Frost lab will be recruiting postdocs soon! (This is super straightforward at the moment, right?)
Joins us for Machine Learning in Computational Biology (MLCB) 2024 mlcb.github.io Submission deadline: June 15 Conference dates: Sept 5 & 6
Wow, we’re on a role! Two covers in two months! For two fascinating stories on the fundamentals of mitochondrial gene expression!
Very excited to see our work featured on the cover of the latest edition of Molecular Cell. Check out our manuscript to learn more about how the nuclear genome works together with the highly polyploid mitochondrial genome across the cell.
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