TF binding papers 📚 NucPosDB database @TF_binding_bot
Papers on transcription factor binding #TFbinding. Maintained by @TeifLab. Also see @nucleosome_bot, @CTCF_papers, @DNAbinding, @cfDNA_papers, @generegulation generegulation.org/nucposdb Joined August 2016-
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Footprint-C reveals transcription factor modes in local clusters and long-range chromatin interactions [Liu et al, 2024] nature.com/articles/s4146… ▶️At one-dimensional level - modes of TF co-occupancy ▶️At pairwise contact level - multiway chromatin interactions of different TFs
Animal Stem cells probably appeared 700-800 million years ago. We found that two key molecules that make our stem cells the way they are even older than that as they even existed before the evolution of animals. 1/n
Perspectives on Codebook: sequence specificity of uncharacterized human transcription factors biorxiv.org/content/10.110… ▶️This preprint provides a summary of the release of a bunch of new preprints by the Codebook Consortium (see three posts below). #TFbinding
Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors (Vorontsov et al, 2024) biorxiv.org/content/10.110… ▶️Codebook: 4,237 experiments, 394 human proteins ▶️Codebook Motif Explorer mex.autosome.org
GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors (Jolma et al., 2024) biorxiv.org/content/10.110… ▶️TFs possess sufficient intrinsic specificity to independently delineate cellular targets
Extensive binding of uncharacterized human transcription factors to genomic dark matter (Razavi et al., 2024) biorxiv.org/content/10.110… ▶️166 uncharacterized human TFs ▶️"Dark TFs", mainly bind closed chromatin enriched for transposable elements ▶️Some Dark TFs contain KRAB domain
Emerging links between phase separation and transcription factor haploinsufficiency [Reiner Veitia] cell.com/trends/genetic… #TFbinding
An atlas of conserved transcription factor binding sites reveals the cell type-resolved gene regulatory landscape of flowering plants biorxiv.org/cgi/content/sh… #biorxiv_genomic
CTCF binding landscape is established by the epigenetic status of the nucleosome, well-positioned relative to CTCF motif orientation biorxiv.org/content/10.110…
Hurry up! Last day to submit abstract for "Genomics in Ageing and Disease" (Colchester, 16th September). Free Registration! Talks by @Peter_Fraser1, @_parker_aim, @GabriellaFicz, @EnrightAnton, @R_Rahbari, @ozgendeniz_, @jordanatbell, @sj_marzi & Essex PIs gate.essex.ac.uk
The registration deadline for our FREE conference in Colchester is prolonged until 1st September. The conference itself is on 16th September. Short talk slots available, hurry up!
The registration deadline for our FREE conference in Colchester is prolonged until 1st September. The conference itself is on 16th September. Short talk slots available, hurry up!
We have an opening for a three-year postdoctoral position for a researcher with expertise in machine learning and genome bioinformatics, to work on cancer diagnostics (liquid biopsies). Please apply here: vacancies.essex.ac.uk/tlive_webrecru…
Registration (free!) and abstract submission now open! Please, spread the word. gate.essex.ac.uk
We are organising a conference "Genomics in Ageing and Disease", 16th September 2024, University of Essex, Colchester. More details soon gate.essex.ac.uk
We are organising a conference "Genomics in Ageing and Disease", 16th September 2024, University of Essex, Colchester. More details soon gate.essex.ac.uk
TFscope: systematic analysis of the sequence features involved in the binding preferences of transcription factors genomebiology.biomedcentral.com/articles/10.11…
Our paper on nucleosome repositioning in breast cancer is now published in Clinical Epigenetics! …lepigeneticsjournal.biomedcentral.com/articles/10.11… ▶️Nucleosome gain marks deregulated TFs ▶️Shorter distances between nucleosomes in cancer ▶️NRL affected by gene expression, methylation, H1 histones, repeats
Our work on the identification of new pioneer transcription factors is out, in collaboration with @YunhuiP @DavidLandsman @TeifLab elifesciences.org/articles/88936
Exploring Data-Driven Chemical SMILES Tokenization Approaches to Identify Key Protein-Ligand Binding Moieties dlvr.it/T1ByQF
Mitotic bookmarking redundancy by nuclear receptors in pluripotent cells dlvr.it/T1ByKz
D-box-binding protein alleviates vascular calcification in rats with chronic kidney disease by activating microRNA-195-5p and downregulating cyclin D1 dlvr.it/T16blq
Anshul Kundaje (anshu... @anshulkundaje
27K Followers 3K Following Federally funded academic research is the innovation engine of the US economy. Reform is welcome. Destruction will have long term consequences.
Ming "Tommy" Tang @tangming2005
41K Followers 2K Following Director of bioinformatics at AstraZeneca. YouTube at chatomics. On my way to helping 1 million people learn bioinformatics. Also talks about leadership.
Anders Sejr Hansen @Anders_S_Hansen
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Nucleosome papers �... @Nucleosome_Bot
5K Followers 8 Following Publications about nucleosomes. Maintained by @TeifLab. Also see @TF_binding_bot, @CTCF_papers, @cfDNA_papers, @generegulation. @[email protected]
Patrick Cramer @mpgpresident
14K Followers 577 Following President of the Max Planck Society since 2023 – dedicated to advancing science for the benefit of society. | @maxplanckpress
Gene Regulation @generegulation
14K Followers 6K Following Gene regulation community. #chromatin #nucleosome #TFbinding #CTCF #cancer #epigenetics. Personal views do not represent @TeifLab. Mostly moved to 🦋 and 🐘
Jian Ma @jmuiuc
8K Followers 1K Following Ray and Stephanie Lane Professor of Computational Biology at CMU School of Computer Science @CMUCompBio @SCSatCMU @CarnegieMellon
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3K Followers 2K Following Assistant Professor, Biochemistry Department, Transcription & Chromatin biology, Outdoor enthusiast, Dog lover (otters too), Occasional politics 🇵🇭🇺🇲🇨🇦
Tineke Lenstra @tinekelenstra
1K Followers 399 Following
Nadine Vastenhouw @NVastenhouw
3K Followers 713 Following Molecular biologist with interest in transcription, chromatin, and developmental biology, slowly migrating to @nvastenhouw.bsky.social. The time is now.
Matthias Spiller-Beck... @Lovin_Chromatin
1K Followers 1K Following Find me on bluesky! This platform here is not something I can be part of. I will keep my account for a while but ask all my science followers to migrate over!
Victor V. Lobanenkov @boris_ctcf
2K Followers 5K Following Verifiable facts and personal notes related to paralogous CTCF & CTCF Like BORIS factors which share eleven near-identical DNA\RNA\protein-binding Zn fingers
Alejo Rodriguez-Frati... @AlejoFraticelli
11K Followers 7K Following Quantitative analysis of aging/cancer heterogeneity - @fraticellilab @icreacommunity @IRBbarcelona @ERC_research @criscancer @CaixaResearch 🇦🇷🇪🇺🇺🇸
James Briscoe @briscoejames
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Josh Brickman @josh_brickman
3K Followers 556 Following Developmental and Stem Cell Biologist, Interested in the transcription, lineage specification, potency and plasticity. @josh-brickman.bsky.social
Johanna Gassler @johanna_gassler
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EPIC_Unit@pasteur @pablonavarroLAB
2K Followers 550 Following research group at the Institut Pasteur and Revive Labex studying gene regulation in stem-cells
Sudhir Thakurela/स�... @sudhirthakurela
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ella @ella1448333
35 Followers 3K Following
Salaar Khan @Salaar_Khan96
7 Followers 47 Following
Hannah Uckelmann @HannahUckelmann
528 Followers 346 Following Max-Eder Junior Research Group Leader at the Goethe University Frankfurt. Studying the epigenetic regulation of stem cell programs in leukemia.
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218 Followers 948 Following
د. مريم محمد... @Dr_MariamMatar
25K Followers 4K Following ⚀Physician-Geneticist ☞Founder 5NGO, Chairperson UAEGDA ♲V Chairman Dubai Cares ▶1st♀Director G Dubai Govt. ▶1st♀Undersecretary MOH
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164 Followers 409 Following Chemistry & Computers, Chess, Trekking, Cycling ...
Erna Magnúsdóttir @magnuslab
344 Followers 524 Following Group leader and associate professor at The University of Iceland Biomedical Center. Transcriptional regulation gets me out of bed in the morning.
Vinay Mahajan @Vinay_S_Mahajan
78 Followers 389 Following Immunologist | Molecular Pathologist | Bioengineer | Brigham & Women's Hospital
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Michael Betti @mjbetti
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Franci Taglini @franci_tag
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きんぐ @LyjNBNHmc8ZpTIX
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Center for Epigenomic... @CEpigenomics
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Jean-François Ouimet... @JeffOui94
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Nucleosome papers �... @Nucleosome_Bot
5K Followers 8 Following Publications about nucleosomes. Maintained by @TeifLab. Also see @TF_binding_bot, @CTCF_papers, @cfDNA_papers, @generegulation. @[email protected]
Gene Regulation @generegulation
14K Followers 6K Following Gene regulation community. #chromatin #nucleosome #TFbinding #CTCF #cancer #epigenetics. Personal views do not represent @TeifLab. Mostly moved to 🦋 and 🐘
Teif Lab @TeifLab
3K Followers 2K Following Teif lab at @uni_of_essex. We work on nucleosomes, chromatin, TFbinding, CTCF, cfDNA. Find us at 🐘 and 🦋. [email protected]; [email protected]
International Nucleom... @INC_COST
1K Followers 312 Following COST Action CA18127 Chair @kerstinbys, vice chairs @mamartirenom & @apombo1 Communication: @SarahBages & @TeifLab INC Academy seminars: https://t.co/yh76Tkdkbh
Cancer epigenetics pa... @epicancerpapers
1K Followers 11 Following Literature bot: cancer epigenetics papers/preprints. Maintained by @TeifLab. Also see @cfDNA_papers, @DNAbinding, @CTCF_Papers, @TF_binding_bot, @Nucleosome_Bot
cfDNA papers 📚 Nuc... @cfDNA_papers
619 Followers 10 Following Papers on cell-free DNA (#cfDNA). Maintained by @TeifLab. Also see @nucleosome_bot, @CTCF_papers, @DNAbinding, @TF_binding_bot @generegulation
Transcription Factors @AllAboutTFs
2K Followers 3 Following I will tweet about TFs: past, present and some future. Tweets are not endorsements. Follow for more TF related science.
DNA-binding drugs📚 @DNAbinding
669 Followers 20 Following PubMed bot reporting DNA-drug and DNA-ligand binding. Maintained by @TeifLab. Also see @TF_binding_bot, @Nucleosome_Bot, @CTCF_Papers, @generegulation
MED_COMPLEX @MED_COMPLEX
1K Followers 252 Following I'm the Mediator Complex but you can call me MED. I'm essential for gene transcription & my best friend is the RNA pol II. And I have a head, a body & a tail.
CTCF Papers 📚 @CTCF_Papers
3K Followers 9 Following PubMed bot reporting all CTCF papers. Maintained by @TeifLab. Also see @TF_binding_bot, @Nucleosome_Bot, @generegulationTrends for United States
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