Special edition of #LCSOSynthesisProblem including problems used in past hiring interviews for both PhD and post-doc positions at @LcsoLab linkedin.com/feed/update/ur…

This week on the #LCSOSynthesisProblem Jerome challenged us with the mechanisms from @BogerLab, Sukbok Chang group, Harada/Nemoto group, and Tian group. Can you solve them? Take a look: epfl.ch/labs/lcso/wp-c…

This week on the #LCSOSynthesisProblem @DuncanBrownsey challenged us with the total synthesis of (+)-Kalmanol, from the Jia Research Group in @angew_chem Take a look: epfl.ch/labs/lcso/wp-c… Original paper: onlinelibrary.wiley.com/doi/10.1002/an…

Can you complete the forward synthesis of (+)-Randainin D without seeing its structure? On the last #LCSOSynthesisProblem Christine challenged us with its synthesis by @Baudoin_Group in @J_A_C_S. Take a look: epfl.ch/labs/lcso/wp-c… Original paper: doi.org/10.1021/jacs.4…

The #LCSOSynthesisProblem is back! Can you predict the outcome of these radical cyclizations? This week @najung_lee_ challenged us with the synthesis of (−)-Phaeocaulisin A by @GroupProcter in @J_A_C_S. Take a look: epfl.ch/labs/lcso/wp-c… Original paper: doi.org/10.1021/jacs.2…

Ever wondered what goes into making the medicines we rely on? This week in #LCSOSynthesisProblem Adriana @adriana_faraone challenged us with the total synthesis of new drugs approved in 2020. @ACSBioMed Take a look: epfl.ch/labs/lcso/wp-c… Original paper: pubs.acs.org/doi/10.1021/ac…

This week in #LCSOSynthesisProblem Helena @helsoleav challenged us with the total synthesis of Leonuketal by Brimble @BrimbleM and @Phillip_S_Grant in @JOC_OL #TotalSynthesis Take a look: epfl.ch/labs/lcso/wp-c… Original paper: doi.org/10.1021/acs.or…

This week in #LCSOSynthesisProblem @EmmaGabRobert challenged us with the total synthesis of Conidiogenone B by Zhai and coworkers @PKU1898 in @angew_chem #TotalSynthesis Take a look: epfl.ch/labs/lcso/wp-c… Original paper: doi.org/10.1002/anie.2…

This week in #LCSOSynthesisProblem @DuncanBrownsey challenged us with the total synthesis of Wickerol A and B by Gui and coworkers @Jinghan_Gui in @J_A_C_S. #TotalSynthesis #Chemistry Take a look: epfl.ch/labs/lcso/wp-c… Original paper: pubs.acs.org/doi/10.1021/ja…

This week in #LCSOSynthesisProblem @PierrePalamini challenged us with the total synthesis of Illisimonin A by Kalesse's group from @UniHannover in @J_A_C_S. #TotalSynthesis #Chemistry Take a look: epfl.ch/labs/lcso/wp-c… Original paper: pubs.acs.org/doi/epdf/10.10…

This week in #LCSOSynthesisProblem Christine challenged us with the total synthesis of Puberuline C by Inoue in @J_A_C_S ! @TotalSynthesis #TotalSynthesis Take a look: epfl.ch/labs/lcso/wp-c… Original Paper: pubs.acs.org/doi/full/10.10…

#LCSOSynthesisProblem of the week with @EmmaGabRobert challenged us with the total synthesis of (+)-Caldaphnidine J by Jing Xu @SUSTechSZ in @NatureComms ! #TotalSynthesis Take a look: epfl.ch/labs/lcso/wp-c… Original paper: nature.com/articles/s4146…

This week in #LCSOSynthesisProblem @Vlad__Smyrnov challenged us with the synthesis of (-)-Himalensine A from the @dixon_group in @J_A_C_S ! #TotalSynthesis #Chemistry Take a look: epfl.ch/labs/lcso/wp-c… Original Paper: pubs.acs.org/doi/10.1021/ja…

#LCSOSynthesisProblem of the week with @diacavalli who challenged us with the syntheses of Cyclocitrinol and (-)-Longithorone A by @Jinghan_Gui and Shair in @J_A_C_S ! Take a look: epfl.ch/labs/lcso/wp-c… Original papers: pubs.acs.org/doi/epdf/10.10… pubs.acs.org/doi/epdf/10.10…

#LCSOSynthesisProblem by Jerome this week! Can you propose a plausible mechanism for the formation of the four drawn compounds from @J_A_C_S @JOC_OL @ChemCommun and @angew_chem ? Take a look: epfl.ch/labs/lcso/wp-c…

Retrosynthesis week in #LCSOSynthesisProblem! Duncan challenged us to find pathways for the synthesis of key intermediates in total syntheses starting from Carvone derivatives in @angew_chem @J_A_C_S @JOC_OL #Retrosynthesis Take a look: epfl.ch/labs/lcso/wp-c…

This week in #LCSOSynthesisProblem @PierrePalamini challenged us with the synthesis of Cephinoid P by Gao @ECNUER in @J_A_C_S ! #TotalSynthesis #Chemistry Take a look: epfl.ch/labs/lcso/wp-c… Original article: pubs.acs.org/doi/10.1021/ja…

First #LCSOSynthesisProblem of the year! Adriana challenges us with the synthesis of Aleutianamine by Tokuyama @TohokuUniPR in @J_A_C_S. Take a look: epfl.ch/labs/lcso/wp-c… Original Paper: pubs.acs.org/doi/epdf/10.10…

A full year of total synthesis, retrosynthesis and mechanistic problems!🧪Check out our website to find them all! More than 160 organic chemistry exercises and more in 2024! #LCSOSynthesisProblem @EPFL_CHEM_Tweet #TotalSynthesis #Chemistry Take a look: epfl.ch/labs/lcso/synt…

This week in #LCSOSynthesisProblem Josh challenged us with the synthesis of Pleuromutilin by Pronin @UCIChemistry in @J_A_C_S ! #Chemistry #TotalSynthesis Take a look: epfl.ch/labs/lcso/wp-c… Original Paper: pubs.acs.org/doi/pdf/10.102…