James Scarth @james_scarth
Postdoc with @McclellandLab @QMBCI • PhD @UniversityLeeds @OncoVirus_Leeds • HPV, replication stress and chromosomal instability London, England Joined February 2013-
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McClelland lab hosted @RaksawanD for a year to collaborate with myself & @mollyguscott to study processes of chromosomal instability in cholangiocarcinoma. Our work is finally out in @JPathology
Checkout our latest research @SpringerNature in @NatureComms rdcu.be/eBqBI A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells. A collaboration with Mike Boemo’s team @SubashkRAI @BonfimMeloA @PaulinePfuderer
A bit late to post but glad to see our review on novel oncogenic mechanisms of the HPV oncoproteins. Great work from undergraduate student Denise in my lab @BiochemSoc @BiochemBiomedUS #HPV portlandpress.com/biochemsoctran…
Great to have this review published in @oncogenejournal! Excellent work from PhD student Louisa @BiochemBiomedUS @Sussex_Cancer @SussexUni #HPV #ubiquitin nature.com/articles/s4138…
My final PhD thesis paper can now be found as an accepted manuscript in @genomeresearch! Using long read sequencing, we found fascinating methylation patterns at HPV integration events that align with fusion transcript production. See here for more! genome.cshlp.org/content/early/…
Happy to share our latest work showing that KSHV can modify paraspeckles to function as hubs for viral RNA processing. Great work by Katie Harper, Ellie Harrington, Connor Hayward in collaboration with @caanenedr, Wiyada Wongwiwat and @DrRobWhite. eur03.safelinks.protection.outlook.com/?url=https%3A%…
Congratulations to Prof Sarah McClelland @McClellandLab at BCI who has been awarded £1.5m by @CRUKresearch. We spoke to Prof McClelland about her plans to investigate the genetic chaos within cancer cells ⤵ 📰 bci.qmul.ac.uk/grants-awards/… @QMULBartsTheLon | @CRUKCOLcentre
Had an excellent week in Edinburgh attending @IPVSociety #IPVC2024. Very honoured to have been awarded the Basic Science Poster Prize for my work on understanding HPV-induced chromosomal instability during cancer initiation!
Congratulations to @james_scarth for winning the @MicrobioSoc Basic Science ECR poster prize at @IPVSociety
📢Awesome talk alert! A reminder that @McclellandLab will be giving a Chromosomal Instability lecture tomorrow👇Zoom link: cam-ac-uk.zoom.us/j/84115680528?… Meeting ID: 841 1568 0528 Passcode: 491672 Don't miss it- Sarah's lab work is terrific! @markowetzlab @DKFZ @emblebi @CRUKCamCentre
Congratulations to lab alumnus @EthanLMorgan on winning the ECR prize at @IPVSociety conference. Well deserved award!!
Come and join a friendly, productive lab doing impactful tumour virology research. Take a look at some of the recent papers published by our PhD students. nature.com/articles/s4146… nature.com/articles/s4138… nature.com/articles/s4138…
Come and join a friendly, productive lab doing impactful tumour virology research. Take a look at some of the recent papers published by our PhD students. nature.com/articles/s4146… nature.com/articles/s4138… nature.com/articles/s4138…
Glad to see this finally published! My final work from my postdoc @nidcd @NIH Great work from everyone involved! @CRC_AACR #HNSCC #Radiation #NFkB aacrjournals.org/cancerrescommu…
I am super excited to show our work, now published in NAR @NAR_Open, on the structural function of SLF1 at the stalled replication fork. @AstburyCentre @ScienceLeeds academic.oup.com/nar/article/do…
So proud of ex-lab member @james_scarth presenting his amazing data on replication stress from the @McclellandLab #HPV #DNATVM2025
So pleased to see this finally out in @NatureComms !! Huge team effort led by @MollyRPatterson with help from @joecogan3, @EthanLMorgan, @james_scarth and Twitter-less colleagues. @BBSRC @The_MRC @ScienceLeeds @wellcometrust nature.com/articles/s4146…
Read this paper which demonstrated that the actin-binding protein LASP1 is upregulated in cervical cancer and correlated with poorer overall survival ➡️ go.nature.com/4eSark0 @oncogenejournal @OncoVirus_Leeds @EthanLMorgan
Great to see this finally out @oncogenejournal! @SussexLifeSci @ScienceLeeds @MollyRPatterson @james_scarth @emmaryder964 @AmyTurn67763683 @iainmorgan26 @OncoVirus_Leeds and everyone else involved 🎉🎉 #HPV #LASP1 #CervicalCancer nature.com/articles/s4138…

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