Bull Group Chemistry @jamesabull
Organic Chemistry Research Group at Imperial College London. Synthesis; Catalysis; Heterocycles. Updates on group news and papers. Account run by JAB imperial.ac.uk/people/j.bull Imperial College Joined June 2009-
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Imine directing groups have a privileged position in C-H functionalization - but when is an imine directing group a transient imine directing group? A discussion of this Concept out now in @ChemEurJ. @jamesabull, @TszKanMa1, @impchem. onlinelibrary.wiley.com/doi/10.1002/ch…
5 Lecturer/Senior Lecturer/Reader/Prof posts available in the world leading Chemistry Dept @imperialcollege. All areas of chemical science considered. Deadline: 26th April Apply now! #Chemistry @Chemjobber @RoySocChem #ChemistryJobs #STEMjobs @ukchemjobs imperial.ac.uk/jobs/search-jo…
Amazing news! We are excited about this huge milestone as it brings more partnership opportunities and training for our students. Congratulations to the team on this achievement! #Chemistry #AI
Amazing news! We are excited about this huge milestone as it brings more partnership opportunities and training for our students. Congratulations to the team on this achievement! #Chemistry #AI
Enantioenriched spirocyclic azetidine oxindoles prepared using an SF5-containing chiral phase-transfer catalyst, reported in #OrgLett by @jamesabull, @ACSpiveyGroup, and coworkers @impchemistry. Check it out: pubs.acs.org/doi/10.1021/ac…
Exciting PhD studentship available in our group @impchemistry with UCB: Phosphine Oxides as Rising Stars in Medicinal Chemistry. Details and applications here: imperial.ac.uk/chemical-biolo…
When is an Imine Directing Group a Transient Imine Directing Group in C–H Functionalization? …see out our Concept on transient C-H functionalisation by Joe and @TszKanMa1, as accepted article @ChemEurJ. dx.doi.org/10.1002/chem.2…
Congratulations to George for his work on sulfoximine diazo compounds, out now in Org Lett @JOC_OL: Synthesis of Pyrazolesulfoximines Using α-Diazosulfoximines with Alkynes pubs.acs.org/doi/10.1021/ac…
Here's our Top 5 most-viewed #JOrgChem research articles published in 2023, check out what your friends and colleagues were finding interesting 👇 dx.doi.org/10.1021/acs.jo… dx.doi.org/10.1021/acs.jo… dx.doi.org/10.1021/acs.jo… dx.doi.org/10.1021/acs.jo… dx.doi.org/10.1021/acs.jo…
My favorite 2023 #PfizerChemistry publications #12daysOfPapers 8/n: A really impactful study on benzylic/strained ring radicals delivering med chem relevant fragments #ChemCollabs with @jamesabull @impchemistry @duarte_group @OxfordChemistry in @JOC_OL doi.org/10.1021/acs.jo…
We are advertising for a postdoc to join our 4-membered rings project: jobs.ac.uk/job/DDX319/res… Come join us @impchemistry! #oxetanes #bioisosteres #latestagefunctionalization
We are advertising for a postdoc to join our 4-membered rings project: jobs.ac.uk/job/DDX319/res… Come join us @impchemistry! #oxetanes #bioisosteres #latestagefunctionalization
Read a new perspective in #JMedChem on the benefits and challenges of oxetanes in drug discovery campaigns ➡ go.acs.org/6cv @JR_Chemistry @jamesabull
📢 Annual Review Meeting - register now bit.ly/29_Annual_Revi… Leading early career academics will deliver a series of review lectures covering a range of topics, including key areas of contemporary synthetic organic chemistry.
The oxetane is now a serious medchem building block- but it comes with some caveats that are nicely illustrated in this perspective: Oxetanes in Drug Discovery Campaigns | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…
For all interested in the ring of rings: our perspective on oxetanes in drug discovery is out now in #JMedChem: @jamesabull pubs.acs.org/doi/epdf/10.10…
Great look at the utility of oxetanes in medicinal chemistry from Juan and @jamesabull out in J Med Chem @ACSBioMed I have a L/H relationship with oxetanes - 1 in particular (in this review) lives rent-free in my head due to its synthetic complexity doi.org/10.1021/acs.jm…
Looking for a good read? Try the Sept edition of @OPRD_ACS Items of Interest for some of the best recent chemistry - Highlights from @SongLinLab @spfletcher @AThomasLab @SchindlerLab @jamesabull @KBrownLab and so many more! doi.org/10.1021/acs.op…
Right now we have my #PfizerChemistry colleague Charlie Choi discussing small rings and our #ChemCollabs with the @jamesabull lab #ACSFall2023
Right now we have my #PfizerChemistry colleague Charlie Choi discussing small rings and our #ChemCollabs with the @jamesabull lab #ACSFall2023 https://t.co/ui1Iglq1iz
Great work going on I’m the @jamesabull lab!!
Great work going on I’m the @jamesabull lab!!
J. Am. Chem. Soc. @J_A_C_S
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Congratulations, Alistair! This is fantastic news. Wishing you all the best on this new adventure at @UTDallasChemBio. Academic life often consists of small achievements; enjoy each one along the way :). You'll be in excellent company with @CisnerosRes, among others!
In August I will be joining @UTDallasChemBio to start my research group! Thank you to many (@duarte_group , @EdAndersonGroup, @mhg_group, ...) for your support. You can find out about my group's plans here: labs.utdallas.edu/sterling/ More very soon... @UT_Dallas @UTDScience
In August I will be joining @UTDallasChemBio to start my research group! Thank you to many (@duarte_group , @EdAndersonGroup, @mhg_group, ...) for your support. You can find out about my group's plans here: labs.utdallas.edu/sterling/ More very soon... @UT_Dallas @UTDScience
Your annual reminder to avoid azide reactions in DCM #ChemTwitter #ChemSafety pubs.acs.org/doi/full/10.10…
@BagPhos Very good, brief communication on the safety issues around azides. Open access too. pubs.acs.org/doi/10.1021/ac…
Second Generation Catalytic Enantiosele (Darren J. Dixon and co-workers) @dixon_group @KenYamazaki5 @formica_michele @branislav_ferko @OxfordChemistry @OxfordSynthesis #openaccess onlinelibrary.wiley.com/doi/10.1002/an…
Kudos to Claire Montagnon for her PhD dissertation and defense @UniGe_OrgChem. Well done. Thanks to @MichelRickhaus and @jamesabull for a great viva thanks to your expertise.
Delighted to share that our work on nodes, kinetic energy and chemical bonding is out now in @J_A_C_S! doi.org/10.1021/jacs.3… @mhg_group #compchem @UCBerkeley @UCB_Chemistry @BerkeleyLab
My first contribution as part of the @mhg_group attempts to answer tricky questions surrounding the origins of the chemical bond. You can read it on @ChemRxiv here: go.shr.lc/3ryIKIT #compchem @UCBerkeley @UCB_Chemistry @BerkeleyLab (1/3)
Brilliant week at #ACSSpring2024 in New Orleans, it was nice to present some of the flow chemistry we are doing in the @crimmingroup
🎉CONGRATULATIONS to Dr. @AMajidChem 🎉on passing her viva yesterday! 🎓! Can’t wait to see what you achieve next! Thanks to @GroupThomas and @FuchterMatt for examining
Big congratulations to @AnnabelBasford for her first first author paper just accepted and available as an accepted article online in @ChemicalScience 🎉 pubs.rsc.org/en/content/art…
Following on from the @UKRI_News announcement, thrilled to share that our CDT in Chemical Synthesis for a Healthy Planet has been funded by the EPSRC. A joint centre between @OxfordChemistry and @GreenChemYork, the first students will start in October 2025.
£46m PhD boost as three Centres for Doctoral Training funded at Imperial imperial.ac.uk/news/251995/46…
📢 The Institute of Chemical Biology's Centre for Doctoral Training has been renewed by the @EPSRC. With £26M cash and in-kind funding, it will support over 100 PhD students and equip them for the #LabOfTheFuture @imperialcollege @impchemistry #ChemicalBiology
Awesome news-great to hear @icbcdt renewed by @EPSRC . Will play key role in training >100 Phds, molecular technology development, lab of future, huge uk wide SME-industry engagement and economic growth of the @WCIDLondon. @RoySocChem @upstream @imperialcollege @StephenCowan
📢 The Institute of Chemical Biology's Centre for Doctoral Training has been renewed by the @EPSRC. With £26M cash and in-kind funding, it will support over 100 PhD students and equip them for the #LabOfTheFuture @imperialcollege @impchemistry #ChemicalBiology
Enantioenriched spirocyclic azetidine oxindoles prepared using an SF5-containing chiral phase-transfer catalyst, reported in #OrgLett by @jamesabull, @ACSpiveyGroup, and coworkers @impchemistry. Check it out: pubs.acs.org/doi/10.1021/ac…
Super cool paper by @jamesbull & @ACSpiveyGroup must read !
Enantioenriched spirocyclic azetidine oxindoles prepared using an SF5-containing chiral phase-transfer catalyst, reported in #OrgLett by @jamesabull, @ACSpiveyGroup, and coworkers @impchemistry. Check it out: pubs.acs.org/doi/10.1021/ac…
Interested in the pentafluorosulfanyl group? The synthesis of substituted pyrazoles bearing an SF5 group under flow conditions with @BelangerChabot and coworkers published in @JOC_OL: pubs.acs.org/doi/10.1021/ac…. #fluorine @ChimieUL @FSGulaval @universitelaval
Our fragments-in-the clinic list is updated! At least 7 approved drugs started as fragments, with many more moving through clinical trials practicalfragments.blogspot.com/2024/02/fragme…
It has been a true honour to share the scene with such an amazing group of scientists. Thank you, @BlavatnikAwards, for recognizing our work and supporting UK science
Esteemed colleagues and friends – without further ado - the Laureates 🥇 and Finalists 🥈of the 2024 Blavatnik Awards for Young Scientists in the UK🇬🇧 ! bit.nyas.org/3SlXLIK