Journal of Leukocyte Biology @jlb_journal
Since 1964, JLB has published first-rate research on immunology-related topics, with emphasis on leukocyte physiology and behavior within the immune system. academic.oup.com/jleukbio United States Joined January 2019-
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Low peripheral blood HLA-DR+CD3+ T cell counts 3 mo post allogeneic stem cell transplantation are associated with an increased transplant-related mortality & higher rate of cGvHD grade 2 to 3. Check out this article by Koeck et al and more in #JLB buff.ly/TZ3QI4P
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Cao's team shows how treponema pallidum lipoprotein TpF1 regulates METTL14-mediated NF-κB signaling pathway to promote macrophage M2 polarization in the latest issue of #JLB buff.ly/R63y7Ok
The bactericidal and thrombotic potentials of extracellular TRAP-enclosed neutrophil vesicles released in response to Staphylococcus aureus at high glucose concentration. Want to learn more? Check out this #JLB article by Mohan and others buff.ly/Lci0bKT
Take a look at this #JLB research article by Kalinina and others. Secreted cyclophilin A regulated the functional activity of T and B cells, influencing the development of the adaptive immune response. buff.ly/aWvoJYD
Neutrophil proteins & RNA are present in megakaryocytes & platelets of patients with myeloproliferative neoplasm, suggesting the transfer of biological constituents occurred during megakaryocyte emperipolesis. Learn more in #JLB Collinson et al buff.ly/vEJzr9n
SLB 2024 legacy award presentation: Mechanisms of immune suppression in sepsis/shock: one investigator's/lab group's experience. Take a look at this review Alfred Ayala in the latest issue of #JLB buff.ly/p8g4qF6
Take a look at this research article in #JLB by Liu et al to learn how tumor-infiltrating CD103+CD8+hnRNPA2B1+ tissue-resident T cells can serve as an unfavorable prognostic factor for ccRCC patients. buff.ly/4K6yCcy
An IL-15-modified NKp30×HER2 trispecific NK cell engager enhances NK cell activation and tumor cell killing. Learn more in this #JLB research article by Cheng and others. buff.ly/0xClOnY
Take a look at this #JLB review by Nussbaumer and others as it highlights the critical role of posttranslational sialylation in regulating neutrophil biology and examines its potential as a therapeutic target in inflammation, infection, and cancer. buff.ly/gOkdkUe
Check out the latest issue of #JLB! buff.ly/1bZoEF1
Check out this article Roy's team Ribosomal protein L13a regulates macrophage polarity in the latest issue of #JLB. buff.ly/UQ7Hk1I
Learn how downregulation of MicroRNA-93 inhibits proliferation and promotes apoptosis and hematopoiesis in myelodysplastic syndrome cells through PAG1-mediated epidermal growth factor receptor signaling pathway in this #JLB article by Liu and others buff.ly/saYt65j
Berbamine promotes autophagy and GPX4 expression through inducing abundant ROS to restrict HIV-1 and Mtb coinfection in macrophages. Learn more in this #JLB research article by Zhou and others buff.ly/gD5FjZW
Check out this #JLB article by Zúquete et al showing how aged DCs stimulated via TLR2/TLR4 produce less TNFα and more IL-10, and prime CD4+ T cells to a less pronounced type-1 cytokine expression profile with reduced levels of the gut homing receptor CCR9. buff.ly/QXXzu8G
This study by Sun's team found that histone-lysine N-methyltransferase 2D can antagonize the AKT-mTOR pathway by upregulating SMG1 expression through histone methylation, thereby promoting ferroptosis in diffuse large B-cell lymphoma cell. #JLB buff.ly/a0FLlaM
Apolipoprotein A-I is preferentially expressed by a subset of human neutrophils with high side-scatter as a potential counter-regulatory, feedback mechanism to attenuate excessive inflammation. Find out more in this #JLB article by Yao and others buff.ly/e5vTtYF
Check out the #JLB article by Phillips et al to learn how microscale arrays enabled the characterization of the neutrophil swarming response to the hyphae of Candida albicans & provided insights into molecular mechanisms that drive & regulate the process. buff.ly/340My9z
Tumor-associated neutrophils play a crucial role in fostering an immunosuppressive microenvironment that enables tumor immune evasion. Dive into this #JLB article by Xiao to learn more! buff.ly/ZCJArer
In a peanut allergen model, we observed significant sex-based differences in immune response and circadian clock gene expression. To find out what we learned, take a look at this #JLB brief report by Santhosh Kumar Duraisamy and Isaac Kirubakaran Sundar buff.ly/eIyTIVr
Take a look at this #JLB research article by Teghanemt and others! Mutation of mazF in Staphylococcus aureus decreases susceptibility to killing by hypochlorous acid and by human neutrophils. buff.ly/KwUVKdH
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