Kyle Skalenko @kskalenko
New Jersey, USA Joined March 2024-
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BTR: a bioinformatics tool recommendation system academic.oup.com/bioinformatics…
1000s of ligand-binding #riboswitch classes likely remain hidden in bacterial transcripts. In @NAR_Open, we report many new candidate #ncRNA classes (including the opuB riboswitch candidate shown below) discovered by careful bioinfo analysis of 50 genomes. tinyurl.com/yj2n47sj
1/42 New preprint: turns out MuLTEE is not only the longest running multicellularity evolution experiment (1000 days and counting), but also the longest running polyploidy evolution experiment! It reveals how whole-genome duplication (WGD) arises and impacts long-term evolution.
Re-defining how mRNA degradation is coordinated with transcription and translation in bacteria biorxiv.org/cgi/content/sh… #biorxiv_micrbio
Non-antibiotic pharmaceuticals are toxic against Escherichia coli with no evolution of cross-resistance to antibiotics by @DrRebeccaJHall, @alanmcn1, @CarterL_J, @JessicaMABlair, @MBottery @AnnSnaith, @SJElement, et al. in @npjAMR nature.com/articles/s4425…
Bioinformatics Copilot 1.0: A Large Language Model-powered Software for the Analysis of Transcriptomic Data biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
RStudio Tutorial for Beginners buff.ly/3vS2SIj #Rstudio #RStats
The “ORBIT for E. coli” paper is out in Nucleic Acids Research! doi.org/10.1093/nar/gk… **Perform genetics (e.g. deletions) without any PCR / cloning – just transform an oligo!** The paper demonstrates benefits over λ Red & shows how oligos scale to high throughput libraries.
For anyone who is interested, the slides from this training session can be found here: cghlewis.github.io/ncme-data-clea…
For anyone who is interested, the slides from this training session can be found here: cghlewis.github.io/ncme-data-clea…
Artificial Intelligence Programming with Python: From Zero to Hero amzn.to/3J8qY4t
Crafting Elegant Scientific Documents in RStudio: A LaTeX and R Markdown Tutorial by Numbers around us buff.ly/3Q14S7T #rstats #rmarkdown #rstudio
Harnessing RNA-based DNA repair pathways for targeted gene editing
Harnessing RNA-based DNA repair pathways for targeted gene editing https://t.co/Xf02Hu1TRH
Here is text and equation (2b) where Peter Higgs described his boson in his 1964 @PhysRevLett (free to read) journals.aps.org/prl/abstract/1…
Foldseek got published in 2024 in Volume 42 of @NatureBiotech. Here is the timeline of FS releases: Source code: 2021/07 Webserver: 2022/01 Preprint: 2022/02 Journal: 2023/05 Print: 2024/02
Foldseek got published in 2024 in Volume 42 of @NatureBiotech. Here is the timeline of FS releases: Source code: 2021/07 Webserver: 2022/01 Preprint: 2022/02 Journal: 2023/05 Print: 2024/02
The intricate relationship of G-Quadruplexes and bacterial pathogenicity islands. elifesciences.org/articles/91985…
1/ figeno: Tool for making genomics figures in python. github.com/CompEpigen/fig…
"Nobody else took what I was doing seriously, so nobody would want to work with me. I was thought to be a bit eccentric and maybe cranky" Peter Higgs, the physicist who discovered the theoretical mechanism explaining the origin of mass in the universe, has passed away today.
SIMPLIFY Science Writing by Roberto — Writing is an essential part of all scientific endeavors. Yet it is rare to find a scientist that finds it easy, not to mention joyful. I am not much different. But after many years at it, I have... Read More > tinyurl.com/2ksfprh2
RNA language models predict mutations that improve RNA function bioRxiv biorxiv.org/cgi/content/sh…
New review in @npjAMR: Co-selection for antibiotic resistance by environmental contaminants by @LauraMayMurray, @_AprilHayes, @WillHGaze, @KasprzykHordern, @ProfJRSnape & @AimeeKMurray (@ECEHH, @UniofExeterESI) nature.com/articles/s4425…
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116 Followers 131 Following PI @ Institut Pasteur of Shanghai, CASPriyanshu Gupta @Priyans08860213
59 Followers 166 Following 3rd yr UG (Chem) at IISc, Bengaluru | KVPY fellow | GATE-CY '24 AIR 51 |Nikhil @Narendradev_N
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24K Followers 8K Following Amateur 🌿 Biologist • Aspiring 🌺 Designer Researcher at Binomica Labs • Degreeless Heathen • Petunia Breeder • Open Lab Notebook: https://t.co/umYTLluuuwBrier Gallihugh, M.S @Brier_Gallihugh
623 Followers 965 Following Aspiring Data Scientist | #RStats | Psych Doctoral Candidate | Prejudice & Discrimination | He/Himplasmidsaurus @plasmidsaurus
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22K Followers 520 Following Fulbright Scholar at @Bushschool of @TAMU • Former Senior Advisor at @NSCofGeorgia • Focused on Russian National Security and Foreign Policy • Views my own"Shoot for the stars – maybe you'll hit the moon" George Church is a pioneer of personalized genomics and synthetic biology & has co-founded >50 companies. On the Night Science Podcast he discusses embracing outliers and taking calculated risks podcasts.apple.com/us/podcast/geo… @geochurch
@NASAWebb isn’t foaling around with its level of detail! 🐴 Just recently, Webb captured the sharpest infrared images of the Horsehead Nebula to date. Learn more photos and see comparisons: go.nasa.gov/3Uy7wEW
Biology System Description Language (BiSDL): a modeling language for the design of multicellular synthetic biological systems bmcbioinformatics.biomedcentral.com/articles/10.11…
NEW 🚨 AstraZeneca could pay £255m for ‘defective’ Covid vaccine after admitting it can cause rare blood clot side effect insiderpaper.com/astrazeneca-co…
NEW 🚨 Earth received a laser message from 140 million miles away: NASA rb.gy/dlp4o0
Does anyone know tutorials for mass spec proteomics data analysis from raw data to quantification?
The Genome Explorer Genome Browser biorxiv.org/content/10.110…
BTR: a bioinformatics tool recommendation system academic.oup.com/bioinformatics…
In vitro transcription-based biosensing of glycolate for prototyping of a complex enzyme cascade doi.org/10.1101/2024.0…
A former surgeon general is sounding the alarm that the current situation with bird flu feels like 2020 all over again — and warned that the virus could jump to humans any day now insiderpaper.com/were-repeating…
Always handy to have a negative strip of Western blot that you can use four times in the same figure! One of the corresponding authors is a Nobel Prize winner @Stanford, the other one works @scrippsresearch. #ImageForensics pubpeer.com/publications/2…
#MicrobiologyMonday: Some bacteria trigger formation of host membrane protrusions that poke into neighboring cells & blip off into vacuoles harboring bacteria, which emerge and trigger additional intracellular spread. Learn more in #IAIJournal: asm.social/1PZ
Build a FREE Chatbot in Python w/ Google Colab #python morioh.com/p/26ea3fabcc55…
Advancements in the Application of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) mdpi.com/2218-273X/14/4…
It's been 25 years since I studied complex analysis, but all I can remember is that every complex integral is a multiple of π
Very cool paper in Science by the Baker Lab at UW. Screening of 15M macrocycles is enabled by our AIMNet machine learning potential! #compchem Can you imagine what we can do with a 2nd generation of AIMNet2 💪🏻🦾 science.org/doi/10.1126/sc…