Matthew Sapio @matthew_sapio
Pain neuroscience in Maryland. All views are my own. Bethesda, MD Joined June 2022-
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A cannabinoid bitopic, biased and peripheral agonist analgesic with limited tolerance and tetrad in Nature. Work led by @Vipin36590264 with @robgereau @DrorLab kaavya Krishna Kumar @WashUClinPharm @WashUanesthesia A short thread nature.com/articles/s4158…
Just watched the full House hearing & testimony of NIH Director Dr. Monica Bertignolli. A few takeaways: • the proposed budget, in addition to not increasing for inflation, wants to condense NIH from 27 to 15 institutes. The NIH does not think this is a good idea. 🧵1/?
𝗦𝗧𝗔𝗠𝗣: single cell (spatial?) Being asked what I think about it (NOT involved). 1) What is STAMP? Should I care about it? STAMP is a clever way of using 𝘀𝗽𝗮𝘁𝗶𝗮𝗹 𝗮𝘀𝘀𝗮𝘆𝘀 to get 𝗶𝗻𝘀𝗮𝗻𝗲𝗹𝘆 𝗹𝗼𝘄 𝗰𝗼𝘀𝘁 𝘀𝗶𝗻𝗴𝗹𝗲 𝗰𝗲𝗹𝗹 𝗱𝗮𝘁𝗮 tinyurl.com/nwetc3te
Our lab is heading to #ANES24 @EllenStaedtler @sademed Looking forward to seeing what’s next for Anesthesiology!
Our work on differential expression of the mu opioid receptor gene in the human DRG is online! Thanks to @m_iadarola , @matthew_sapio and all others! cell.com/cell-reports-m…
Check out articles like “Analgesic candidate adenosine A3 receptors are expressed by perineuronal peripheral macrophages in human dorsal root ganglion and spinal cord microglia” by @m_iadarola @matthew_sapio et al. in #PAIN bit.ly/3B5dS7x
New in Neuroscience Biobehavioral Reviews. What is the evidence that #centralsensitization causes persistent pain?
Great perspective on mentoring. Especially liked the part on the ‘‘temperature’’ of a mentor’s style, and how it can change over the course of mentorship, and according to the current needs of the mentee cell.com/neuron/fulltex…
I am so, so excited to share that I am starting my own lab at the Medical College of Wisconsin @MedicalCollege in the Dept of Cell Biology, Neurobiology, and Anatomy @MCW_CBNA!! The Sheahan Lab will open its doors in October and study how neuropeptides shape somatosensation. 1/6
Last week I finished pain fellowship, concluding a nearly 20 year journey of training & life. What a ride! So what is next? I'm thrilled to announce that I will be starting my integrated lab and clinical practice @WashUPain focused on the study and treatment of #neuropathic pain.
I know we get lots of emails from NIH, so it is easy to miss things. Anyone living with, treating or researching #Chronicpain, this is important! Now is the time to provide input on the future of pain research @ the NIH HEAL Initiative. @NIHendaddiction grants.nih.gov/grants/guide/n…
Grats 🎉
Years ago Martin Rasmussen was on a Fulbright studying meningeal afferents in my lab & noticed dyes placed in CSF accumulate in trigeminal ganglia. This observation nucleated his PhD project in @NedergaardLab & has now led to a new model of migraine pain. science.org/doi/10.1126/sc…
We would love to receive your submissions! DM me any questions! #singlecell #spatial #research
We would love to receive your submissions! DM me any questions! #singlecell #spatial #research
Truly a joy and an honor to see our work highlighted in this commentary by @m_iadarola , Peter Burbelo, @matthew_sapio and Andrew Mannes!
Is there a better argument to increase @NIH budget? Report: Every dollar of NIH research funding doubles in economic returns fiercebiotech.com/research/repor…

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