Michael Pitcher @michaeljpitcher
Active at https://t.co/l5CyEg3eqb michaeljpitcher.com Joined January 2015-
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New government funding will unlock AI's potential. 🔬£85m Research Venture Catalyst programme, supporting projects by @AstonUniversity's MEMetic, Pharos AI and Bind Research 💻£7.8m to support collaboration between UK and EU experts on AI and High-Performance Computing
Could tolerance to DNA be broken in the gut in systemic lupus erythematosus? In our latest review we explore whether tolerance to DNA can be broken when undigested DNA from microbiota in GALT directly encounters B cells unrestricted by T cell dependence doi.org/10.1016/j.imle…
After leaving the bone marrow, transitional B cells split into subsets w/ biased expression of homing receptors and different surface IgM levels. Spencer & Dionisi @JoSpencerLab discuss how this could contribute to human lymphoid tissue content & function hubs.la/Q02JSNWX0
Our latest perspective piece is out now in @JExpMed! Here we propose that recruitment of immature B cells could contribute to human lymphoid tissue structure and function. rupress.org/jem/article/22…
Lots of amazing work on display at Spatial Biology Research @ King’s symposium, a pleasure for our postdoc @michaeljpitcher to showcase our work with the Spatial Biology Facility, using @nanostringtech CosMX to study B cells in gut lymphoid tissue @KCLcancer_pharm @JelmarQuist
There are still tickets left for the "Spatial Biology Research @ King’s" symposium on July 11! Join us to find out more about spatial transcriptomics with CosMx from @michaeljpitcher (@JoSpencerLab), @LabSpagnoli and many more! …gy-research-at-kings.eventbrite.co.uk
Proud to joint-author with Lucia Montorsi on this latest paper from our lab, using spatial transcriptomics, imaging mass cytometry and more to investigate feature of autoimmunity present as interacting features of healthy gut
Proud to joint-author with Lucia Montorsi on this latest paper from our lab, using spatial transcriptomics, imaging mass cytometry and more to investigate feature of autoimmunity present as interacting features of healthy gut
New review of GALT and B cells from our lab and @BemarkMats is out now in @TrendsImmuno !
New review of GALT and B cells from our lab and @BemarkMats is out now in @TrendsImmuno !
Our review for Trends on the current knowledge of GALT is now out. We discuss its organisation, the role of GALT in B cell development, its role in autoimmunity and T cell help to B cells. Thanks to @JoSpencerLab and @michaeljpitcher for the collaboration. doi.org/10.1016/j.it.2…
Gut-associated lymphoid tissue: a microbiota-driven hub of B cell immunity dlvr.it/T39fjH #immunology
Thank you so much Prof Jo Spencer @JoSpencerLab for a fascinating exploration of how #imc #imaging #masscytometry in tissue-based research can reveal surprising scientific findings...🔬🦠🧬🎆🫢 #tcell #GALT #autoimmunediseases #Lupus @KCLImmunoMicro @ChokshiLab @DrAntonioRiva
New preprint from our lab out now!
Our letter, "Heritable diversity in the human antigen inexperienced B cell repertoire", is out now in Molecular Immunology! We show TS & naïve B cells have more similar gene expression if they are from the same clone @michaeljpitcher authors.elsevier.com/c/1hF1QalRWKCg3
So proud to share the latest paper of the Taams lab, out in #CellReports just now! Big congrats to @giopovo, Lucy & Lizzie and all other co-authors for great teamwork between immunologists, rheumatologists, molecular biologists and bioinformaticians @KCL_CIBCI @KCLImmunoMicro
Happy that a review written together with @JoSpencerLab human on gut inflammation and B cells is now out in @NatRevGastroHep. In it we discuss induction of gut responses, tissue sampling problems, and changes during IBD, coeliac disease and autoimmunity. nature.com/articles/s4157…
Our editorial with @BemarkMats @Thomas_J_Tull detailing the first installment of excellent reviews that focus on human B cells is out in @CEIjournal. Stay tuned for further papers in the series later this year! doi.org/10.1093/cei/ux… Thread of papers in the series below ⬇️
"Antibiotics should only be prescribed where they are necessary and supported by a clinical assessment." Abx need protecting - the negative impact of abx use at the individual (gut microbiome) & community (future #AMR infections) level of high abx use cannot be underestimated.
"Antibiotics should only be prescribed where they are necessary and supported by a clinical assessment." Abx need protecting - the negative impact of abx use at the individual (gut microbiome) & community (future #AMR infections) level of high abx use cannot be underestimated.
Amazing performance of My Neighbour Totoro at the Barbican last night @totoro_show
📢📢📢Exciting new PhD opportunity in our lab (joint project with @TheCrick) : ⭐️Detailed characterisation of the enlarged GCs present in the LNs of TNBC to determine their immune cell interactions using novel and established experimental technologies.⭐️ crick.ac.uk/careers-study/…

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