Micha Fridman @mifridm
Israel Joined January 2019-
Tweets362
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Followers273
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Following225
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Likes436
Delighted to share the first-in-class CB1R PROTAC degrader study published in ACS Pharmacology & Translational Science! Peripherally restricted to avoid brain penetration—opening new possibilities in cancer and beyond. Congrats Aseel on your work! pubs.acs.org/doi/full/10.10…
New paper from the lab, we present a facile chemoselective method to derivatize PGNs in unprotected forms and in aqueous solution. Congrats team! pubs.acs.org/doi/10.1021/ja…
Biochemical Applications of Microbial Rare Glycan Biosynthesis, Recognition, and Sequencing | Biochemistry pubs.acs.org/doi/10.1021/ac… Congrats to Joanna, Andrea, Hanee, Antara, Seayoung and Mia on their review on the many biochemical applications of "rare" sugars.
Thank you to the @acs_carb for nominating me. Very honored to receive this @AmerChemSociety recognition
Four unique & exciting opportunities to work in at the interface of fungal biology, assay development and medicinal chemistry in partnership with industry and drug discovery experts with @ElaineBignell @BallouLab @gordon_d_brown at @MRCcmm and @DDU_Dundee
Four unique & exciting opportunities to work in at the interface of fungal biology, assay development and medicinal chemistry in partnership with industry and drug discovery experts with @ElaineBignell @BallouLab @gordon_d_brown at @MRCcmm and @DDU_Dundee
New paper from the Kürti Lab! We report a Rh-catalyzed one-pot alkene oxyamination that delivers N–H unprotected β-amino γ-lactones. No protecting groups. Broad scope. Late-stage functionalization. Congrats to Agustin (@agustinmrt) & Young-Do (@YDK0627)! pubs.acs.org/doi/full/10.10…
Happy to report our latest paper on „A broadly applicable stereospecific glycosylation“ out in Nature Synthesis in collaboration with Liming Zhang nature.com/articles/s4416…
In this preprint, we use fluorescent probes derived from all three clinically used polyene antifungals to reveal distinct localization patterns in pathogenic yeast and vacuolar sequestration in resistant strains. chemrxiv.org/engage/chemrxi…
Check out our latest work with @JaviRamSor @AdrianMulholla1 @dengbowen9373 @chemistry_mike @DoudouLu319, Sofia Oliveira and others @BristolChem on a new bridged azobenzene with reversible photocontrolled binding to a G-Quadruplex DNA/Duplex junction. pubs.acs.org/doi/10.1021/ja…
Our latest work with @MykhailiukChem @EnamineLtd is now published in @J_A_C_S (pubs.acs.org/doi/10.1021/ja…)! O-Vinylhydroxylamines undergo N-arylation with aza-arene N-oxides to deliver 7-azaindolines/azaindoles via a pericyclic cascade process. Congratulations to Charlotte & Zach!
We are happy to share that our article on chirality-driven non-equilibrium assembly is now published in @angew_chem ! 🎉Congrats to Lenard and Kun for showing how left and right handed aminoacyl phosphates enable control over kinetics and pathways. onlinelibrary.wiley.com/doi/10.1002/an…
Our new study titled 'Direct Cellular Screening of Pd-Mediated Arylation of Cyclic Peptide Binders of Ubiquitin Chains: Towards Modulating NEMO Liquid–Liquid Phase Separation' has just appeared in JACS. thanks to the amazing team that drove this work to such an exciting level
@glycoworld #glycotime article #236 Cooperatively Catalyzed Activation of Thioglycosides with Iodine and Iron(III) Trifluoromethanesulfonate mdpi.com/3413856 #mdpimolecules via @Molecules_MDPI
Excited to share our new paper published in JACS Au! "Druglike Molecular Degraders of the Oncogenic RNA-Binding Protein HuR" We report the first-in-class degraders of HuR using both molecular glue & PROTAC approaches pubs.acs.org/doi/10.1021/ja… Congrats Liann for this amazing work!
Really happy to receive the 2025 Emil Fisher Award in Carbohydrate Chemistry @eurocarb22 @BristolChem jointly with @FlitschSabine . Looking forward to the rest of the meeting.
We're happy to announce our paper about the structural elucidation of the antifungal lipopeptide AFC-BC11 from Burkholderia cepacia complex incl. insights into central steps of its biosynthesis published in @J_A_C_S ! Congratulations, @leizhong94 🥳 pubs.acs.org/doi/full/10.10…
Controlling the Helicity and Handedness of Polyaromatics with Isobenzofuranophane -Angewandte Chemie International Edition - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/an…
🎊It has been a long and tough journey💪, but the paper is finally out online. Excited to share this work led by my first PhD student, Chenyu elucidating the structures and functions of natural bacteria-derived PGNs in the host gut. doi.org/10.1038/s41467…
Prof. Jin-Quan Yu (@YulabJin) will receive the 5th Akira Suzuki Award for his research on C–H bond activation, which makes it easier to build complex molecules. His work accelerates advances in pharmaceuticals, molecular tools and materials science. More: ow.ly/z0BL50WhOQf
Check out our recent collaborative work with Raymo and Sortino groups on discovering green-light activatable BODIPYs for super-resolution imaging of live cells: Photoactivation of BODIPY Fluorescence with Green Light | The Journal of Organic Chemistry pubs.acs.org/doi/abs/10.102…

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Angewandte Chemie @angew_chem
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The Nobel Prize @NobelPrize
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