Nicolas De Neuter @ndeneuter
Scientific Leaders Programme Associate - Data Science & Digital Innovation @GSK. Opinions expressed are my own. Antwerp, Belgium Joined March 2017-
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We all agree sequencing TCR repertoires is great, but figuring out what epitopes your TCRs are targeting is so much better. Here we present the reverse epitope discovery pipeline: (cell.com/cell-reports-m…). Led by @pogorely, @elisarosix, @Minervina_Asya in @CellRepMed (1/8)
Types of AIRR Papers in two chapters – because we had too many good ones 😂. A team effort of the Greiff and @SandveGeir lab members. @airr_community
Check out in @FrontAging: we studied how antigen-specific T-cell repertoires change during aging and CMV-infection. Really enjoyed the team effort with great people from @rivm and @CTI_UMCUtrecht @BinfUtrecht
Check out in @FrontAging: we studied how antigen-specific T-cell repertoires change during aging and CMV-infection. Really enjoyed the team effort with great people from @rivm and @CTI_UMCUtrecht @BinfUtrecht
My @airr_community/@TheAbSociety webinar on immune receptor (BCR, TCR) data analysis is now available on-demand for free (including the slides and written answers to all webinar questions; also those we did not have time to answer during the webinar): antibodysociety.org/learningcenter…
What determines the hierarchy of T cell clone sizes? Check out our new study to see what large scale repertoire sequencing combined with mathematical modeling can tell us about this important question. doi.org/10.1101/2020.0…
Just 10000 TCRbetas are enough to distinguish you from any other person on Earth, including your potential evil twin (first author: @ThomasDupic) biorxiv.org/content/10.110…
New preprint from a collab. with Phil Bradley @fredhutch! Linking T cell receptor sequence to transcriptional profiles with clonotype neighbor graph analysis (CoNGA). We apply CoNGA to several TCR and GEX datasets (1/5) 1st author @sschattgen biorxiv.org/content/10.110…
Building further on the great work by the groups of @antigenomics and @grigory_efimov , we created a TCR-epitope prediction model for the #SARS-CoV-2 epitope YLQPRTFLL for use in #AIRRseq data and #COVID19 studies. Check it out at tcrex.biodatamining.be! @biominaBE @UAntwerpen
1/5 Was a great pleasure to collaborate with Grigory Efimov's @grigory_efimov lab on the analysis of T-cell repertoires in #COVID-19 patients, identifying public T-cell responses to #SARS-CoV-2 antigens in #COVID-19-exposed donors. Main findings of [medrxiv.org/content/10.110…] are:
Happy to share our preprint (arxiv.org/pdf/2005.08290…) about longitudinal deep TCRseq after mild #COVID19 (first author: @Minervina_Asya). Two donors, both were sampled before and on day 15, 30, 37, 45 timepoints post-infection. (1/10)
Our collaborative project (@pogorely, @elisarosix, @BensoudaMeriem, @an_franke, @ChudakovM and others) about longitudinal #TCR repertoire sequencing after #SARSCoV2 infection is now also on biorxiv. biorxiv.org/content/10.110…
A big day for @ndeneuter, defending his PhD on machine learning for immunology decision support. PhD nr 9 in my @biominaBE team @UAntwerpen !
Open postdoc position in the Matsen group at Fred Hutch ift.tt/2GHIDjm
We find granzyme positive CD8 T cells next to degenerating neurons in hippocampi of Alzheimer’s patients. A smoking gun and a dead body but more work will be needed to prove that that gun killed the neuron. More here nature.com/articles/s4158… and here …g-stanford-edu.laneproxy.stanford.edu/2020/01/08/sus…
The @TcrexTool paper demonstrating the identification of the epitope specificity of TCR repertoires using our prediction models and enrichment analysis approach has been published in @FrontImmunol! frontiersin.org/articles/10.33….
We have a new job opening @UAntwerpen @biominaBE for a postdoc in the area of artificial intelligence for small molecule structure elucidation. Please spread the vacancy. #vacancy #AI #mass #spectrometry bit.ly/2PFnWKf
Our latest preprint on how the prediction of TCR-epitope recognition can be framed as an image classification problem is now available on @biorxivpreprint (biorxiv.org/content/10.110…).
Our tool "RTCR surpassed all other tools in both recall and accuracy" "RTCR is the best choice" has been benchmarked to be best again! @BinfUtrecht @UMCURRCI #TCR Tools for fundamental analysis functions of TCR repertoires: a systematic comparison academic.oup.com/bib/advance-ar…
Extremely proud of my PI @KrisLaukens for making it to the top 3 promising AHA! award nominees of @AntwerpSrl 's Innovation Night.
Talk by Ayse Bassez from the KUL on single cell RNA and TCR seq of biopsies of breast cancers treated with pembrolizumab. #ATCR19
MiXCR @_mixcr_
539 Followers 1K Following Leading software for the analysis of NGS data for immune profiling. Posting updates on MiXCR releases and new features.
Beiyun C Liu @beiyun_liu
104 Followers 174 Following Postdoctoral Researcher at St. Jude Children's Hospital. CRI Irvington Fellow. Searching for better ways to communicate and promote primary research papers
Wim Vanroose @vanroose
403 Followers 4K Following Learn by doing. Chair board of directors at Motulus BV. Professor applied math at U Antwerpen.
Alex @alexvujkovic
472 Followers 259 Following 🧬 PhD student in Clinical Virology and Bioinformatics 🧬 @ITMAntwerp @Uantwerpen
George Elias @iGeo85
459 Followers 2K Following Scientist - PhD - Vaccines, T and B cells, Antigen Discovery, Single-Cell Omics, Mucosal Immunity @GSK
Elham @Elham_Kazemirad
394 Followers 5K Following Associate professor Tehran University of Medical Sciences, PhD in Medical Parasitology, Science of Medical Laboratory, Molecular Biology
NEELAM SINHA @neelamsinha05
65 Followers 517 Following Looking for the next career opportunity/Job | Data scientist @Cancer Data Science Lab, NCI | Using ML to find novel cancer therapies & biomarkers
William Amoyal @wamoyal
589 Followers 5K Following Regional Account Manager at Vizgen. Passionate about omics sciences, entrepreneurship, classical music, opera, history. Tweets are my own.
Alex Graudenzi @AGraudenzi
1K Followers 5K Following Tenure track asst professor @unimib || Data science + AI + bioinformatics for cancer and viral evolution || Opinions are my own
Xuan Cindy Li @XuanCindyLi
329 Followers 1K Following Tackling cancer by tracing tumor heterogeneity | Predoc Fellow @cenksahinalp @NCIDataSci @theNCI | PhD Student @BISIumd | Cat mom 🐈| artist 🎨
immuneML @immuneml
788 Followers 525 Following immuneML is a software platform for machine learning analysis of adaptive immune receptors and repertoires | tweets by @milenapavl and @victorgreiff
PIN Immunology Networ.. @PinPhd
91 Followers 168 Following PIN Immunology Network aiming to promote networking and virtual seminars with Ph.D. students to share professional experience and science without borders
Nektarios (Nek) Valou.. @nekvalous
2K Followers 4K Following senior res assoc @DKFZ @NCT_HD; founding/exec editor @immuno_inform; hobbyist photographer—https://t.co/exx6ffCLF0
NicklectedTropicalDis.. @NickdeVrij
549 Followers 935 Following PhD @UAntwerpen @ITMantwerp. Clinical Immunologist/Computational immunology. Epitopes, HLA's, T cells, single-cell RNA+TCR, Nanopore, and Leishmania!
Kilian Schober @kischober
3K Followers 311 Following MD Microbiology & Virology. Understanding & Engineering Human T Cell Immunity @UniFAU. Cycling. BVB. Cinema. Family.
Paul Smyth @smyth7
182 Followers 1K Following Director of AI/ML Engineering at https://t.co/ufs7KwECJ7. Ex-physicist. Mostly interested in deep learning for biological sequences. All opinions my own.
Janarthan @Antaryami786
176 Followers 4K Following Physician Scientist | Viral Immunology | Cell & Gene Therapy | Medical Education
gabbilaw @gabbilaw1
2 Followers 33 Following
Marlies Vanden Bempt @marlies_vdbempt
1K Followers 1K Following Postdoctoral researcher in Hematology @awilkinsongroup @MRC_WIMM @UniofOxford visiting from @KU_Leuven - I love science, talking, and talking about science!
tayer @tayerant
7 Followers 238 Following
Laura Pallett @ljpally19
3K Followers 2K Following UKRI FLF at @iit_ucl. Immunologist w/ interests in #liver immunology, T cells & #immunometabolism. Co-Author: Data Science for Immunologists | She/Her
Carla Luciana Padilla.. @Carlalpf91
836 Followers 3K Following 🇦🇷 PhD Student in @SbgUnq👩💻⚛️ #Bioinformatics & #Biostatistics 🛸 #Proteomics 🟡::🟣 #DigArt @bioinfonoa | @RSGArgentina | @seh2_bioinfo | @iscbsc 🌎
Dr. Tatjana Bilich�.. @TatjanaBilich
1K Followers 5K Following Postdoc @ Mark Davis Lab | Stanford 👩🏼🔬 Human Immunology🔬T-cell enthusiast |Science is magic that works!
Mónica Cabrera-Pasad.. @Monica_CabreraP
1K Followers 2K Following Human Biologist specialized in #Bioinformatics by @UPFBarcelona Now Ph.D. student at @BSC_CNS @CarrerasIJC | @RSGSpain BCN coordinator | @iscbsc #ESCS2022 chair
Mohamed Ghonim @M_A_Ghonim
70 Followers 345 Following
Xizhi Guo @Johnny_Guo
47 Followers 467 Following
Mario Gaimann @MGaimann
170 Followers 1K Following Spicing up #ReservoirComputing with Physics 🌶👨💻 PhD Candidate @SimTechStuttga2 @Uni_Stuttgart with @miriamklk, IMPRS-IS scholar @MPI_IS @Cyber_Valley 👨🔬
Vincent van Unen @VincentvUnen
2K Followers 2K Following Assist. Prof. | Leiden University | Human Immunology | CyTOF | IBD | Single-Cell Analysis | Organoids | former postdoc Mark Davis & Calvin Kuo Lab at Stanford🌈
Dawit A. Yohannes @DawitAYohannes
35 Followers 80 Following Science; Biosciences; Bioinformatics; Immuno-informatics; genomics and NGS data analysis; Data science; Computer programming and software development;
Maria Metsger @immunology_s
166 Followers 276 Following Scientist, bioinformatician. Passionate about systems immunology in aging, cancer and autoimmunity. Admire big and complex omics data at single-cell resolution.
stefan.schattgen @sschattgen
161 Followers 151 Following Scientist | Immunologist | Computational-enthusiast | Dad
Henk-Jan van den Ham @henkjanvdh
118 Followers 278 Following Senior Scientist Bioinformatics & Immunology at @ENPICOM | #RepSeq | pathogen-host interactions | #RStats | Science & Society
Ulrik Stervbo (He/Him.. @UlrikStervbo
1K Followers 945 Following Immunologist with a crush on TCRs: Trying to understand virus reactivation in Tx patients, fluent in #R, #Python - and regex. @ChariteBerlin, @RuhrUniBochum
Milena Pavlović @milenapavl
674 Followers 906 Following Postdoc researcher at Sandve lab @UniOslo interested in machine learning, causal inference and their applications in biomedical sciences 📚💻📚
fanofactor @fanofactor
217 Followers 1K Following #rstats #dataviz #bioinformatics #immcantation Adaptive Immune Receptor Repertoire sequencing (#airrseq)
NASA GeneLab @NASAGeneLab
5K Followers 4K Following
Noyaro @VeronicaNoya4
3 Followers 140 Following
VIB Technology Traini.. @VIBTechTraining
986 Followers 1K Following Training in Life Sciences Technologies is our passion. Interested? Check our website.
Grigorios Koulouras @koulouras_gr
847 Followers 4K Following Scientific Software Engineer @pfizer. Developing software solutions for patients' benefit. @CRUK_SI alumnus #bioinformatics #proteomics #biomarkers & #nullomers
owen bodley @obodley
186 Followers 541 Following Engineering the best future for life on spaceship Earth. @pipe_bio CTO. I like black coffee, red wine and getting muddy outside. Opinions are my own.
Sebastiaan Valkiers @s_valkiers
129 Followers 208 Following Computational immunology, multiple sclerosis. PhD student @UAntwerpen @FWOVlaanderen
HealthBuzz.be @HealthBuzzBE
2K Followers 3K Following The Pulse of Belgian Healthcare. An initiative by @HealthEndeavour. Twitter bot for https://t.co/5FZtECxou0 🤖
Beiyun C Liu @beiyun_liu
104 Followers 174 Following Postdoctoral Researcher at St. Jude Children's Hospital. CRI Irvington Fellow. Searching for better ways to communicate and promote primary research papers
Alessandro Montemurro @mont_alle
24 Followers 28 Following
Camilla Engblom @camillaengblom
925 Followers 606 Following Cancer immunologist interested in how the immune system both keeps us healthy and makes us sick. Assistant Professor at the Karolinska Institute. She/her
Lonneke Scheffer🧬�.. @LonnekeScheffer
252 Followers 166 Following @immuneml Developer ~ PhD Candidate ~ Computational Immunology ~ University of Oslo
Geir Kjetil Sandve @SandveGeir
801 Followers 118 Following Professor in bioinformatics/machine learning at University of Oslo, Norway. Follow me at @[email protected] or at @[email protected]
Ming "Tommy" Tang @tangming2005
30K Followers 2K Following Director of computational biology. On my way to helping 1 million people learn bioinformatics. Educator, Biotech, single cell. Also talks about leadership.
Sai Reddy @saireddy911
811 Followers 339 Following Associate Professor - Swiss Federal Institute of Technology Zurich @ETH_en
Olivier Jeunen @olivierjeunen
903 Followers 523 Following Lead Decision Scientist @Sharechatapp. ML/RecSys PhD from @UAntwerpen. Prev. @AmazonScience, @SpotifyResearch, @Facebook, @CriteoAILab. 🇧🇪 in 🏴
immuneML @immuneml
788 Followers 525 Following immuneML is a software platform for machine learning analysis of adaptive immune receptors and repertoires | tweets by @milenapavl and @victorgreiff
Brian Corrie @bcorrie.. @bcorrie
298 Followers 277 Following Technical Director, iReceptor. Interests: immunology, data science, computational science, computer science, scientific collaboration, visualization
Kilian Schober @kischober
3K Followers 311 Following MD Microbiology & Virology. Understanding & Engineering Human T Cell Immunity @UniFAU. Cycling. BVB. Cinema. Family.
ImmunoInformatics @immuno_inform
742 Followers 54 Following Open access scientific journal that publishes cutting edge research in all aspects of computational immunology. The account is run by the Editors.
Paul Smyth @smyth7
182 Followers 1K Following Director of AI/ML Engineering at https://t.co/ufs7KwECJ7. Ex-physicist. Mostly interested in deep learning for biological sequences. All opinions my own.
NicklectedTropicalDis.. @NickdeVrij
549 Followers 935 Following PhD @UAntwerpen @ITMantwerp. Clinical Immunologist/Computational immunology. Epitopes, HLA's, T cells, single-cell RNA+TCR, Nanopore, and Leishmania!
Prof. Shane Crotty @profshanecrotty
52K Followers 303 Following Vaccines and immune system scientist. Professor, La Jolla Institute for Immunology (LJI), a non-profit research institute @ljiresearch. PhD not MD.
Petter Brodin @BrodinPetter
13K Followers 9K Following Professor of Pediatric Immunology • Pediatrician • Human Systems Immunology • Experiments • Computation • @MRC_LMS • @imperialcollege • @karolinskainst
BioLearning_KULeuven @BioLearning_KUL
116 Followers 125 Following Research group @KU_Leuven #ESAT #STADIUS (Belgium) focused on #machinelearning #deeplearning and #softwaredevelopment in #Bioinformatics and #Chemoinformatics
Maria Metsger @immunology_s
166 Followers 276 Following Scientist, bioinformatician. Passionate about systems immunology in aging, cancer and autoimmunity. Admire big and complex omics data at single-cell resolution.
stefan.schattgen @sschattgen
161 Followers 151 Following Scientist | Immunologist | Computational-enthusiast | Dad
IKMB_BioInfoGen @BioInfoGen1
183 Followers 103 Following Genetics & Bioinformatics Lab @ IKMB, @kieluni. Focussing on all things #IBD by #NGS: (Immuno-)Genetics, (Meta-)Genomics and beyond 🥼🧬🦠
Mike Bogetofte Barnko.. @mikebarnkob
3K Followers 2K Following Doctor (@OUHhospital), Lundbeck post.doc (@KirOxford & @SyddanskUni). Tweets about immunology, immunotherapy & CAR-T. Also at: @[email protected].
Anna Postovskaya @anna_post_
53 Followers 74 Following Aspiring T-cell focused computational immunologist | PhD student @UAntwerpen | @ITMantwerp | @FWOVlaanderen
fanofactor @fanofactor
217 Followers 1K Following #rstats #dataviz #bioinformatics #immcantation Adaptive Immune Receptor Repertoire sequencing (#airrseq)
Milena Pavlović @milenapavl
674 Followers 906 Following Postdoc researcher at Sandve lab @UniOslo interested in machine learning, causal inference and their applications in biomedical sciences 📚💻📚
Henk-Jan van den Ham @henkjanvdh
118 Followers 278 Following Senior Scientist Bioinformatics & Immunology at @ENPICOM | #RepSeq | pathogen-host interactions | #RStats | Science & Society
Sebastiaan Valkiers @s_valkiers
129 Followers 208 Following Computational immunology, multiple sclerosis. PhD student @UAntwerpen @FWOVlaanderen
Joshua Starmer @joshuastarmer
23K Followers 251 Following I make StatQuest videos and sing more than I should. Contact: https://t.co/ZvHk9UJ0Tn
Immunology Wars @ImmunologyWars
2K Followers 1K Following Immunology Wars - educating about immunology and the immune system through characters of the Star Wars movies. Jedi/Sith #MayYourImmuneSystemDefendYou
Aridaman Pandit | अ.. @PanditAridaman
328 Followers 415 Following Senior Principal Research Scientist | Head of Immune Profiling Center | Head of Systems Immunology @Abbvie Autoimmune diseases| TCR Repertoires | Virus dynamics
Antwerp.SRL (smart re.. @AntwerpSrl
258 Followers 381 Following Wij linken onderzoekers en ondernemers. Netwerkplatform van UAntwerpen en Voka - Kamer van Koophandel Antwerpen-Waasland.
Thi Kim Tran-Nguyen, .. @kimthi1011
630 Followers 3K Following Immunology SME👩🏻🔬 | Data Science👩🏻💻| ❤️ Precision Medicine | Genomics | forever Johnnie 📖 | Pro-Am Salsa 💃🏾| Mom of 1 Cat 🇻🇳
Yuval Elhanati @elhanati_yuval
131 Followers 65 Following Theoretical physicist / computational biologist, studying the adaptive immune system, Memorial Sloan Kettering Cancer Center
LiedeweiVandeVondel @LiedeweiVdV
258 Followers 840 Following Genetics of Rare Diseases, Neurology and Statistics. PhD Candidate @UAntwerpen @FWOVlaanderen at the Translational Neurosciences & Peripheral Neuropathies labs
Eytan Ruppin, MD, PhD @NCIEytanRuppin
5K Followers 2K Following Chief, Cancer Data Science Laboratory, CCR/NCI | Computational biology, precision oncology, immunotherapy | Lab-run account Privacy: https://t.co/vMCvc3AIHE
John Castle @joccastle
786 Followers 1K Following Inventing & translating technologies for therapies. ML AI ‘omics & comp biology. Molecular glue for targeted protein degraders. @MonteRosaTx Tweets my own
Chase Donnelly @ChasepDonnelly
39 Followers 109 Following PhD Student - University of Antwerpen - Bioinformatics - Microbial Ecology - Currently working on Regime Shift project studying effect of rain cycles on plants
Bryan Howie @bryan_howie
2K Followers 2K Following Genetics. Statistics. Rock and roll. Feminist AF. Anti-racist, anti-fascist, pro-science. He/him.
Ineabel @carrilloinea
52 Followers 129 Following
alex rubinsteyn @iskander
5K Followers 4K Following Genomics + immunology + ML = personalized cancer immunotherapy. @CompMedUNC @UNC_Lineberger @OpenVax https://t.co/8DWibdgbLI
DiversifyImmuno @DiversifyImmuno
454 Followers 334 Following A resource for symposium organizers, award committees, search committees, etc to identify immunologists who might diversify their pool. Link to list below!
EndeavorBio @EndeavorBio
264 Followers 1K Following Working at the interface between immunology, genomics and big data. We develop software to apply deep learning to immune repertoire sequencing #software
Robert Mettelman @RMettelman
142 Followers 229 Following Virus enthusiast | SJCRH postdoc | Thomas Lab | NIH NRSA Fellow | Influenza and cellular immunity 👾
Concerned bioinformat.. @wetlabsucks
4K Followers 316 Following Bioinformatics memes for genes and proteins
B. Arman Aksoy @armish
2K Followers 5K Following recovering academic @Obsidian_Tx-- yard doc terk @sandercbio @hammer_lab @agenus_bio @moma_tx alumnus #HeartDad #husband #❤︎ #CHD #HLHS @[email protected]
Immunicom @immunicom
627 Followers 708 Following Immunicom is reimagining healing to be affordable & without sacrificing quality of life by developing a non-drug based product to end terminal diseases.
Tony Purcell @tony_purcell8
1K Followers 1K Following research scientist, mass spectrometrist, immunologist, peptide biologist
Len Jia Soon @3583584567
151 Followers 1K Following Passionate about the role of thymus on autoimmunity and T cell development. Also having a predilection for germinal centers. Views are my own. From Singapore🇸🇬
Youzhong @daniellyz1989
50 Followers 113 Following Postdoc #metabolomics data science @janssen pharmaceuticaHow scientists visualize and analyze T cells. @StJudeResearch @sschattgen and I present a short animation on the most classic technique used by immunologists and its evolution to modern day. #scicomm #tcell #immunology blogs.stjude.org/progress/how-s…
Had fun working on this with @beiyun_liu!
There are many kinds of T cells: CD4+ vs. CD8+, effector vs. memory. But how did researchers figure out what they all do? St. Jude scientists use various methods, including some they created themselves. bit.ly/40tLT8Z @beiyun_liu @PGTimmune #StJudeOn
We’ve released an update to our preprint with @anshulkundaje, @ScottBoydLab, @robtibshirani, and many others: “Disease diagnostics using machine learning of immune receptors” #tweetorial 🧵 (1/9)
New work with @anshulkundaje, @ScottBoydLab, @robtibshirani, and many others: “Disease diagnostics using machine learning of immune receptors” #tweetorial 🧵 (1/11)
We are thankful to the @metoyoufonds for awarding @SofieGielis a grant to study the role of the T cell receptor repertoire in Acute Myeloid Leukemia therapy in an interdisciplinary collaboration between @UAntwerpen and @UZAnieuws . Congratulations Sofie!
The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination dlvr.it/SZvg59
Valuable #immunology cell atlas: #scRNAseq + paired B & T cell receptor seq for 330,000 tissue-resident immune cells across 16 human tissues. CellTypist: new & robust immune cells annotation algorithm, finding 101 immune cell types in 1,000,000 cells‼️ Why this is important👇🧵
Presenting Slide-TCR-seq: our method for measuring the transcriptomes of cells & T cell receptor (TCR) sequences in situ! This collaboration w/ Bryan Iorgulescu, Shuqiang Li, Catherine Wu, and @insitubiology led to some cool findings... cell.com/immunity/fullt… 1/8
We analyzed >10 mio TCRs from >1000 samples with TCRGP classifiers trained to detect classic melanoma (eg MART1) and viral antigens Turns out number and phenotype of anti-melanoma T cells are useful in diagnosis, prognosis, and ICI response. Out now: nature.com/articles/s4146…
Clustering TCRs is great, but relating sequence similarity quantitatively to a likelihood of shared epitope specificity is so much better! 😀Here we introduce coincidence analysis, a framework for measuring selection in sequence repertoires: biorxiv.org/content/10.110…
We all agree sequencing TCR repertoires is great, but figuring out what epitopes your TCRs are targeting is so much better. Here we present the reverse epitope discovery pipeline: (cell.com/cell-reports-m…). Led by @pogorely, @elisarosix, @Minervina_Asya in @CellRepMed (1/8)
In a new preprint, we discuss how generalization of biomarkers identified by machine learning may be improved by considering the underlying causal model. A 🧵 1/7 arxiv.org/abs/2204.09291
Huge congratulations to Dr. @wsdewitt for a beautiful thesis defense! I'm going to miss the heck out of you: for your rigorous thought, your love of science, and balanced perspective. You have an amazing career ahead of you... 🎸🚀🤘
We won Best Student Paper for our "Pessimistic Reward Models" at #RecSys2021 and this feels like the perfect conclusion to my PhD. Really happy that the final chapter of my thesis was welcomed so warmly by the community! @goethals
Types of AIRR Papers in two chapters – because we had too many good ones 😂. A team effort of the Greiff and @SandveGeir lab members. @airr_community
Check out in @FrontAging: we studied how antigen-specific T-cell repertoires change during aging and CMV-infection. Really enjoyed the team effort with great people from @rivm and @CTI_UMCUtrecht @BinfUtrecht
New Research: Age and CMV-Infection Jointly Affect the EBV-Specific CD8+ T-Cell Repertoire frontiersin.org/articles/10.33… #Aging
An exciting study authored by one of our joint students with @Dushek. Surface plasmon resonance was used to measure low TCR:pMHC affinities, demonstrating the imperfect nature of the TCR response. biorxiv.org/content/10.110…
My @airr_community/@TheAbSociety webinar on immune receptor (BCR, TCR) data analysis is now available on-demand for free (including the slides and written answers to all webinar questions; also those we did not have time to answer during the webinar): antibodysociety.org/learningcenter…
Which TCRs are more common in the (naive) repertoire than others? We find that many abundant and public TCRβs have no D-segment: biorxiv.org/content/10.110… . Where do they come from and what do they do? A short summary (1/6)
In our latest preprint we introduce the falcon spectrum clustering tool. It uses feature hashing to convert high-resolution MS/MS spectra to low-dimensional vectors, fast similarity searching, and density-based clustering to efficiently process millions of MS/MS spectra.
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