Purvis Lab @purvislab
Building computational models to understand how cells work. genetics.unc.edu/purvislab Chapel Hill, NC Joined April 2013-
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Exciting News! A new video capturing the mission of UNC's Computational Medicine Program. Catch the full video at KathASK Films on YouTube or simply click the following link for direct access: youtube.com/watch?v=YI8nHb… #PurvisLab #ComputationalMedicine #UNCSchoolOfMedicine
Delighted to share that our feature selection method for improving inference of cellular trajectories is out today in @NatureComms! Biggest thank you to @natstann @purvislab @WStallaert @JJMilnerLab + team 😊 Paper: rdcu.be/dCVZA . 🧵below.
Delighted to share that our feature selection method for improving inference of cellular trajectories is out today in @NatureComms! Biggest thank you to @natstann @purvislab @WStallaert @JJMilnerLab + team 😊 Paper: rdcu.be/dCVZA . 🧵below.
How can you use RNA velocity to infer the dynamics of cell signaling from spatial transcriptomic data? Check out our new preprint!
How can you use RNA velocity to infer the dynamics of cell signaling from spatial transcriptomic data? Check out our new preprint! https://t.co/qv3LfAa0Hy
Attending the @CompMedUNC 2nd computational medicine symposium today: From Single Cells to Microenvironments: Computational Medicine at Multiple Scales. Kicking things off is co-director, Charles M. Perou with a video of their last 5 years.
Now in print: Cellograph! A semi-supervised approach to analyzing multi-condition single-cell RNA-sequencing data using graph neural networks. Creative quantitative work by @jamshaid_shahir in close collaboration with @natstann. Read more here: bmcbioinformatics.biomedcentral.com/articles/10.11…
A team from computational medicine, genetics, biostatistics, and surgery studied how cell cycle flexibility allows tumor cells to escape the effect of anti-cancer drugs that target cell division. #UNCResearch #research #cancertreatment #breastcacner go.unc.edu/a7KRe
#RENCI is hiring a #KnowledgeGraphs + #LanguageModels team lead. The candidate will have a deep understanding of #knowledgerepresentation, language models, + #graphbased #datastructures, and will guide the team in developing #nextgeneration #AI solutions. unc.peopleadmin.com/postings/273213
#RENCI is seeking a strategic thinker to join our team as the #DeputyDirector to guide #research efforts, shape #researchstrategy, lead #interdisciplinary teams, & continue to develop RENCI as a world-class center for #datascience + #cyberinfrastructure. unc.peopleadmin.com/postings/272048
“We’ve grown up together as people because we met so young. And we’ve grown up together as scientists too.” Cynthia Bulik and Patrick Sullivan have created a life full of adventure and #research spanning decades and continents. #love #Carolina #valentines go.unc.edu/Kb87L
We are excited to announce Purvis Lab’s newest member! Leah Frazier is a PhD student interested in investigating how changes in cell cycle progression affect the response of breast cancer cells to combination therapies. We are excited to work with you Leah. Welcome to Purvis Lab!
Our very own Tarek Zikry @tarekmzikry completed his Ph.D. Defense. We want to congratulate him on this incredible accomplishment, recognizing all the time and effort that went into his work. Congratulations Tarek!
Excited to have my first-author work from my PhD published! Huge thanks to @natstann and @purvislab for mentoring me on this work. Natalie’s class renewed my love of graphs from college and inspired me to combine it with machine learning and scRNA-seq, and the rest is history.
Excited to have my first-author work from my PhD published! Huge thanks to @natstann and @purvislab for mentoring me on this work. Natalie’s class renewed my love of graphs from college and inspired me to combine it with machine learning and scRNA-seq, and the rest is history.
Very glad to have helped bring this cell cycle reporter mouse to fruition! with @vbautch1 @NatalieTanke and colleagues #cellcycle
Very glad to have helped bring this cell cycle reporter mouse to fruition! with @vbautch1 @NatalieTanke and colleagues #cellcycle
New paper: Most approved drug combinations for advanced cancer (1995-2020) have predictable clinical efficacy, because they have additive effect on Progression-Free Survival times. In @NatureCancer at rdcu.be/drhs0 by @HaeunHwangbo @SC_Patterson @PlanaDeborah 1/6
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Prof. Tim Elston of @UNC_PHCO is receiving our next mentoring shout-out. Congrats to Dr. Elston for creating an engaging and collaborative research environment for his trainees!
Funny how when you collect data you are happy when it is bigger but when you analyze it you wish it were smaller.
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“When I joined, I was basically told to do something interesting...” — Bjarne Stroustrup. An example from AT&T's Bell labs @BellLabs of how science was and should be done.
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And no better companion to hear these advances with that @dana_peer
.@JoleneRanek @natstann @purvislab @CompMedUNC present DELVE, an unsupervised feature selection method to identify core molecular features driving cell fate decisions. #BiotechNatureComms nature.com/articles/s4146…
Prof. @mikelove of @UNC_GMB and @uncbiostat is receiving our next mentoring shout-out. Dr. Love was nominated for being an advocate for his trainees.
Huge honor to be elected to the College of Fellows #AIMBE2024 and especially meaningful to share the stage with my friend and colleague @CathyBodine from @CUDenverBIOE. Much thanks to @KristynMasters for the nomination.
Congratulations to Profs. Keith Neeves and Cathy Bodine for their induction into the AIMBE College of Fellows! @CathyBodine #KeithNeeves @aimbe
.@JoleneRanek @natstann @purvislab @CompMedUNC present DELVE, an unsupervised feature selection method to identify core molecular features driving cell fate decisions. #BiotechNatureComms @NatureComms nature.com/articles/s4146…
Life’s simple pleasures - enjoying a Bob Ross moment after an evening swim
Beyoncé dropping a Jolene cover 😂. Only a matter of time before this becomes the new ice breaker song people sing when they meet me for the first time 😂
Excited to have lineage motifs out in the world. Hoping the concept and methods can be useful in various developmental systems as more lineage data become available. Congratulations to @tranmartink and @AskaryLab on the work, and thanks to Adara Koivula and @Wonderstrucksci for…
Online now: Lineage motifs as developmental modules for control of cell type proportions dlvr.it/T2lKM6
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