Rakesh @rakez_krish
Postdoc @PennMedicine | PhD @iitbombay | Computational Biologist |Website: https://t.co/lTDbH6p2mQ Philadelphia, USA Joined May 2013-
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A paper in @NatureMicrobiol reports that the use of AI to mine proteomes of archaea led to the discovery of archaeasins, antimicrobials that kill drug-resistant bacteria in laboratory and animal models, offering a promising source of future antibiotics. go.nature.com/3JAdi5C
Predicting statistics of gene translocation events: role of chromatin compaction and double-strand DNA break biorxiv.org/content/10.110… #biorxiv_biophys
For over a century, the hunt for new antibiotics has focused almost exclusively on bacteria and fungi. Today, that paradigm shifts. By coupling state-of-the-art AI with the vast, largely uncharted diversity of Archaea, we open a new frontier for molecular discovery. Our APEX…
Our new work "Liquid–liquid phase separation of lamin drives altered chromatin organization in cardiomyopathic mutations of lamin A" is now out in NAR. Experiments by @Subhradip1225, Shreyasi & Duhita. Led by @mithunmittir & Kaushik Sengupta. 🔗shorturl.at/q5qr3
ft. @megclarks, Walter Mowel, @MFMich1, Leonel Joannas, @Notorious_MHC, Isabel Erickson, Jorge Henao-Mejia (@PennPathLabMed), Lexus Johnson, @andyjminn (@UPenn_I3H), @rakez_krish, @delafuentelab (@PennPsych) & @ksimeono (@pennvet) @ImmunityCP cell.com/immunity/abstr…
(1/5) Venoms are a vast, largely untapped library of bioactive molecules—and our new paper in @NatureComms @NaturePortfolio reveals just how powerful they can be. 🐍⚡️nature.com/articles/s4146…
@biorxiv_genomic Excited to share our paper on the changes in 3D chromatin architecture across cell cycle stages in the pathogenic basidiomycete yeast, Cryptococcus neoformans. @ranjithpa @KaustuvSanyal @DimpleNotani @DuttaShuvadip @rakeshnetha_v
🚨 We’re hiring ! 📌 Roles: Sequencing Services – Associate – Business Development, (Freshers) – Area Sales Manager – (3–4 yrs experience) 📍 Delhi, Mumbai, Bangalore, Hyderabad, Chennai 📩 [email protected] #Hiring #NGS #BiotechJobs
🚨 We’re hiring! 📌 Roles: – Associate – Business Development, Sequencing Services (Freshers) – Area Sales Manager – Sequencing Services (3–4 yrs experience) 📍 Delhi, Mumbai, Bangalore, Hyderabad, Chennai 📩 [email protected] #Hiring #NGS #BiotechJobs
🚨 We are hiring ! 📌 Roles: Sequencing Services – Associate – Business Development (Freshers) – Area Sales Manager – (3–4 yrs experience) 📍 Delhi, Mumbai, Bangalore, Hyderabad, Chennai 📩 [email protected] #Hiring #NGS #BiotechJobs
(1/3) New in @ImmunityCP @CellPressNews: A single protein inside mitochondria, NDUFA4, keeps some immune cells in tumors “asleep.” Cutting its levels wakes them up, so they start attacking the cancer cell.com/immunity/abstr…
Thrilled to share our paper on how mitochondrial complex IV remodeling can modulate TAM functions and promote anti-tumor immunity! with @ksimeono, @MFMich1, @Notorious_MHC, @rakez_krish, @delafuentelab, @andyjminn, @JHMLab and those not on X! Out now in @ImmunityCP 🎉
Thrilled to share our paper on how mitochondrial complex IV remodeling can modulate TAM functions and promote anti-tumor immunity! with @ksimeono, @MFMich1, @Notorious_MHC, @rakez_krish, @delafuentelab, @andyjminn, @JHMLab and those not on X! Out now in @ImmunityCP 🎉
Online now: Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity dlvr.it/TLf6cn
The immune system responds like a forest fire unless you control the spark. @raviradhak of @CBE_Penn @pennbioeng and @jakebrenner of @PennMedicine decoded how protein spacing flips the immune “on” switch, paving the way for safer nanomedicine. Read more: bit.ly/4eeGVoG
We have a postdoctoral opening in the Narayanan Lab (narayananlab.com) @UFChemistry @ButlerPolymer. Please apply here: explore.jobs.ufl.edu/en-us/job/5359…
To fight antibiotic resistance, @delafuentelab and @PennDentalMed created mirror-image peptides that kill bacteria and boost immunity. Read more about the new contenders to topple superbugs.
Happy to share my first paper from @delafuentelab!
Happy to share my first paper from @delafuentelab!
(1/7) Traditional antimicrobial approaches directly kill bacteria to treat infections. What if we could instead mobilize the body’s own defenses to defeat them? cell.com/cell-biomateri…
Synthetic peptides targeting a mast cell-specific G protein-coupled receptor MRGPRB2 display anti-infective potential dlvr.it/TL1891 #biomaterials #bioengineering
Martini 3 - IDP is out! Improved parameters for disordered proteins, great work from Liguo Wang: nature.com/articles/s4146…

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