rheelab @rheelab
Rhee Laboratory at Weill Cornell Medicine. Tuberculosis Metabolomics Lab. Managed by lab members. 🧬 🧫 rheelab.weill.cornell.edu New York Joined October 2021-
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biorxiv.org/content/10.110… RNA polymerase-mediated regulation of intrinsic antibiotic resistance and bacterial cell division | bioRxiv
biorxiv.org/content/10.110… Desiccation-induced DNA damage facilitates drug resistance in Mycobacterium tuberculosis | bioRxiv
Molecular mechanism revealed for bacterial sugar overload. doi.org/10.1128/mbio.0… @MRKmicrobes @DoerrLab
Thanks for highlighting this paper, Akos!
Ever wonder why drug-resistant Mycobacterium tuberculosis is less fit than drug-susceptible Mtb? And how the bacterium can evolve to compensate for that cost?
Check out our new book on #metabolomics with @SpringerNature Book link: link.springer.com/book/10.1007/9…
Many many congratulations to Kyle Plank (@PharmaKyle) who successfully defended his PhD today.!! A proud moment for the Rhee Lab.!! Cheers to Dr. Plank 🎉👨🔬🍾🎉🎊 #tuberculosis #thesis #phd #celebration @WCM_ID @WeillCornell @Cornell @saehrt @RockLabTB
Massive congratulations to Dr. @PharmaKyle ! First graduate student from the @rheelab 🥳 passed with flying colors after giving one of the best thesis seminars I've seen! Watch out for this amazing scientist and speaker! 👀
Ever wonder how LysoPC availability regulates heterochromatin maintenance and sexual differentiation in P. falciparum? Check out our study in @NatureMicrobiol. Amazing team effort led by @ChantalTHarris with @rheelab @DeitschKirk @MariaMMota2. tinyurl.com/LysoPC2GCs
On 24 March 1882, German physician and Nobel Prize laureate Robert Koch announced the discovery of the bacterium that causes tuberculosis (TB) - a date marked by #WorldTBDay today.
Great work.!! Role of Rv3645 and the ubiquitous second messenger cAMP in intrinsic multidrug resistance and fatty acid metabolism in Mtb.!! @RockLabTB @PharmaKyle @saehrt @EhrtSchnapLab
Great work.!! Role of Rv3645 and the ubiquitous second messenger cAMP in intrinsic multidrug resistance and fatty acid metabolism in Mtb.!! @RockLabTB @PharmaKyle @saehrt @EhrtSchnapLab
Drs. @KyuRheeMD & Craig Altier lead The Cornell Center for Antimicrobial Resistance Research & Education, uniting scientists from @WeillCornell & @Cornell to enable the dev. of transformative, multidisciplinary solutions to the problem of antimicrobial resistance. #wcmresearch
Interesting work on rpoB and combination therapy by @JohnHelmann and @Yesha_SP…suggesting that multidrug treatment regimens may limit the available pathways for the evolution of antibiotic resistance. @sonivijay07 #drugresistance #rpob #rnapolymerase #bacteria #metabolism
Interesting work on rpoB and combination therapy by @JohnHelmann and @Yesha_SP…suggesting that multidrug treatment regimens may limit the available pathways for the evolution of antibiotic resistance. @sonivijay07 #drugresistance #rpob #rnapolymerase #bacteria #metabolism
The September issue also includes Reviews on branched #ubiquitinchains (@RapeLab et al), #SH3 domains (@LandryChristian & Bisson et al), systems biochemistry (@rheelab @Robert_S_Jansen & Grundner), and bacterial #T3SS (Strynadka et al). bit.ly/3w59fVz
CinA - a protein found in Mycobacterium #tuberculosis - contributes to drug tolerance for #TB treatments, according to researchers from @WeillCornell. Read how it reduces the efficacy of isoniazid and other antibiotics used to treat TB: news.cornell.edu/stories/2022/0…
We are looking for a postdoc to work with our drug combinations team to design multidrug therapies for TB. Please write me if you have an adventurous and team-oriented spirit, attention to detail, and an interest in quantitative biology and machine learning. Please RT!
MSNovelist: de novo structure generation from mass spectra | Nature Methods nature.com/articles/s4159…
Arginine-mediated gut microbiome remodeling promotes host pulmonary immune defense against nontuberculous mycobacterial infection tandfonline.com/doi/full/10.10… Happy to share a new article describing the impact of NTM infection on gut microbiome and their shifted metabolome.
Thank you to all authors, @Robert_S_Jansen @AlexandreGouzy @0098Wang @vdartois1 @rheelab @saehrt and others who are not on twitter.

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