Saurav Roy Choudhury, PhD @sauravimmunity
Immunology Postdoc @MartinLabUofT, @Ucalgary PhD, Interested in IBD, Metabolic Diseases and Cancer, Coffeholic. Toronto Joined February 2012-
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Saurav Roy Choudhury, PhD retweeted
Ever wondered how gut microbes control immune responses at extra-intestinal locations? Here, #theonlylabever reports how a gut protozoan commensal microbe remotely shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria. @CellCellPress ⬇️(1/X)
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Saurav Roy Choudhury, PhD retweeted
The powerhouse analogy has expired Like social organisms mitochondria differentiate and specialize to accomplish complex functions 🧵
The powerhouse analogy has expired Like social organisms mitochondria differentiate and specialize to accomplish complex functions 🧵
Saurav Roy Choudhury, PhD retweeted
#EveryCellIsAnImmuneCell!💥Thrilled💥for our new paper @CellCellPress with @achillebro! We show that, during #IBD, type III #interferons delay gut repair by inducing #pyroptosis in intestinal epithelial cells via #gasdermin C upon ZBP1 activation! 1/n authors.elsevier.com/a/1k2OAL7PXqSL5
Saurav Roy Choudhury, PhD retweeted
One of the most beautiful and famous picture of a mitochondrion
Saurav Roy Choudhury, PhD retweeted
As we celebrate mitochondria awareness week, let's remind ourselves that mitochondria are the processor of the cell The 1957 "powerhouse" analogy has expired 😀 Mitochondria process and transform energy, together with hundreds of other signals cell.com/cell-metabolis…
Saurav Roy Choudhury, PhD retweeted
Energy transformation machinery inside mitochondria
Saurav Roy Choudhury, PhD retweeted
New paper from the martin lab: Phil Barbulescu and Chetan Chana from the @albertoxmartin and Frank Sicheri labs published this article showing that FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation | Nature Communications
New paper from the martin lab: Phil Barbulescu and Chetan Chana from the @albertoxmartin and Frank Sicheri labs published this article showing that FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation | Nature Communications
Saurav Roy Choudhury, PhD retweeted
FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation pubmed.ncbi.nlm.nih.gov/39215025/
Saurav Roy Choudhury, PhD retweeted
Brain-derived cellular communication network factor 3 (CCN3) secreted from KISS1 neurons of the arcuate nucleus (ARCKISS1) functions as a potent osteoanabolic factor to build bone in lactating females @hollyingrahamSF nature.com/articles/s4158…
Saurav Roy Choudhury, PhD retweeted
Science is a career full of rejection & self doubt. Most scientists don't go around collecting awards & kudos but sit there wondering if anyone reads our papers. Telling a scientist whose work you like that you value & appreciate what they do is a small & very meaningful gesture.
Saurav Roy Choudhury, PhD retweeted
For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome. nature.com/articles/s4158…
Saurav Roy Choudhury, PhD retweeted
A vaccine that is effective in the elderly. Pleased to share our study on the use of hyperactivator adjuvants to stimulate anti-tumor immunity in the young and old. All other vaccine adjuvants, and even checkpoint inhibitors, failed to do so. cell.com/cell/fulltext/…
Saurav Roy Choudhury, PhD retweeted
TIME's list of the 100 Most Influential People in the world is out. I'm honored, delighted, and grateful to be a part of this incredible group #TIME100 🙏🏼🙏🏼🙏🏼 @TIME time.com/6964230/akiko-…
Saurav Roy Choudhury, PhD retweeted
How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. nature.com/articles/s4158… @BoXia7
Saurav Roy Choudhury, PhD retweeted
Our review on mitochondria and inflammatory diseases is out now. Is a break in the 2 billion year old endosymbiotic relationship with mitochondria a basis for RA, MS, IBD, asthma and more? rdcu.be/dx4Vv pubmed.ncbi.nlm.nih.gov/38326590/
Saurav Roy Choudhury, PhD retweeted
Just out today, @AnnualReviews publishes our review on all things #Neutrophil, from origin and development, to diversity and roles in #CVD and #cancer. This has been lead with a dream-team of students in the lab: @Aleejandra__ @TVicanolo @ovadia_samuel
Saurav Roy Choudhury, PhD retweeted
Science has named the development of glucagon-like peptide-1 (#GLP1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as the 2023 #BreakthroughOfTheYear. Learn more: scim.ag/5c2 #BOTY
Saurav Roy Choudhury, PhD retweeted
Today marks 100 years since @UofT's Drs. Frederick Banting and John Macleod received the @NobelPrize in Physiology or Medicine for the discovery of insulin. You can read the presentation speech here: bit.ly/46JsPae
Saurav Roy Choudhury, PhD retweeted
I’m thrilled to share my postdoc research investigating the identity and control of regions of the mammalian small intestine. All FIVE of them! Introducing: small intestinal domains A – E. biorxiv.org/content/10.110… a 🧵:
Saurav Roy Choudhury, PhD retweeted
Excited to share our work in @ScienceMagazine - Kupffer cell-like syncytia replenish macrophage function to capture bacteria in a fibrotic liver. Huge congrats to lead authors @moritzpeiseler and @brunaraujodavid on their amazing work!! science.org/doi/10.1126/sc…
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