Scott Dehm @scottdehm
Professor @UMNcancer studying steroid hormones, androgen receptors, and #ProstateCancer genomes. Apogee Enterprises Chair in Cancer Research . Views=mine. pathology.umn.edu/bio/lab-med-an… Minneapolis, MN Joined May 2011-
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Scott Dehm retweeted
It was a sheer pleasure to have @AdamSharpMedOnc here in Minnesota delivering a Cancer Center Seminar lecture about manipulation of the apoptosis pathway for prostate cancer therapeutics. Thanks @scottdehm for inviting and hosting him. Let the collaborations begin! @UMNCancer
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Scott Dehm retweeted
Can anyone top the Halabi model for predicting survival in mCRPC? Yes! Dr Halabi does it again! See our ctDNA based clinical-genetic model in first line ARPI treatment out today in @EUplatinum: sciencedirect.com/science/articl… @scottdehm @DukeGUCancer @DukeCancer @PCFnews
Scott Dehm retweeted
Fascinating work by Chen et al in uncovering new metabolomics of SPOP-mutant prostate cancer, we review here @EAntonarakis @scottdehm nature.com/articles/s4301…
Scott Dehm retweeted
Check out our new work exploring AR biology in advanced prostate cancer: tinyurl.com/2s39jh8b. We found that tumours expressing a specific AR variant (ARv567es) have a distinct transcriptomic profile and are resistant to androgen deprivation and bipolar androgen therapy
Scott Dehm retweeted
🧪 Dr. @scottdehm and collaborators including @huang_lab, @EAntonarakis, & @mishabeltran showed that double-negative #CRPC cells express genes defining basal, club, and hillock epithelial cells from benign #prostate. @PNASNews | bit.ly/4gI7fH3
Scott Dehm retweeted
Thrilled to share a project that we envisioned over a decade ago to perform high purity/high specificity molecular analysis of circulating tumor cells! Led by the brilliant @marina_sharifi and @JSperger @AACR Funded by @PCF_Science @NIH @CDMRP
Thrilled to share a project that we envisioned over a decade ago to perform high purity/high specificity molecular analysis of circulating tumor cells! Led by the brilliant @marina_sharifi and @JSperger @AACR Funded by @PCF_Science @NIH @CDMRP
Excited to share a new paper by postdoc Dr. Kiel Tietz @UMNCancer! CPSF1 inhibition promotes widespread use of intergenic polyadenylation sites and impairs glycolysis in prostate cancer cells: Cell Reports cell.com/cell-reports/f… Work funded by @CDMRP and @NCICancerBio
Scott Dehm retweeted
In memory of Dr. Felix Feng. Thank you @EUplatinum for honoring our beloved colleague and friend, gone too soon. We miss you Felix @MaryFengMD @nlinmd @PCF_Science sciencedirect.com/science/articl…
Scott Dehm retweeted
The two faces of FOXA1 muts in PCa. Congrats to Justin Hwang for this revised classification of FOXA1 alts in PCa. Different FOXA1 classes have different biologic behaviors, clinical outcomes & racial clustering, esp. Class 1B and 2. @UMNCancer @scottdehm aacrjournals.org/clincancerres/…
Scott Dehm retweeted
PROSTATE Paper 2 Franseschini et al. developed a targeted DNA methylation assay for the detection of neuroendocrine prostate cancer using plasma cell-free DNA with an AUC > 0.93. Their assay also quantifies tumor content and offers a phenotype evidence score, which reflects…
Scott Dehm retweeted
It is this time of the Year again: 10 TOP TRANSLATIONAL PAPERS IN GU ONCOLOGY! 1/ Prostate Paper 1 Fonseca et al. introduced a machine-learning approach that predicts whether patients with #mCRPC have sufficient ctDNA% for informative genotyping. This study addresses a critical…
Scott Dehm retweeted
PROSTATE Paper 3 Knutson et al. developed the AR-ctDETECT assay to detect ctDNA in limiting plasma cfDNA from pts w/ #mCRPC in @ALLIANCE_org A031201 ph3 trial of enzalutamide w/ or w/o abiraterone. The ctDNA assay was able to prognosticate outcomes, as pts w/ mCRPC who were…
Scott Dehm retweeted
AR alterations inform circulating tumor DNA detection in metastatic castration resistant prostate cancer patients out in Nature Communications nature.com/articles/s4146… This study introduces a custom circulating tumor DNA (ctDNA) 🧬sequencing assay, AR-ctDETECT, designed to…
EllisLab_ @EllisLab_
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Adam Sharp @AdamSharpMedOnc
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Salma Kaochar @Kaochar2
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43K Followers 409 Following Chief GU Cancers @DanaFarber; Prof Medicine @HarvardMed; ⚽ lover; 🚲@PanMass rider.
Adam Sharp @AdamSharpMedOnc
4K Followers 3K Following Academic medical oncologist. Interested in biology, prostate cancer and drug development. Husband/Dad/Sport. Views my own and no specific advice/DMs.
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5K Followers 643 Following The official Twitter account for scientific news from the Prostate Cancer Foundation. Follow us at @PCFNews @ https://t.co/CB3q1YYabC
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Prostate Cancer Found... @PCFnews
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Postdoctoral Associat... @PostdocsUMN
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University of Minneso... @UMNAlumni
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AACR President Lillia... @AACRPres
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674 Followers 271 Following
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385 Followers 3K Following
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119 Followers 469 Following University of Minnesota Pharmacology! Garrulous. Moody.Floaty.Ambitious.Lazy. Just a bunch of more adjectives. I don't do summaries. I talk. duh!
Pernilla Wikström @Pernilla_Wik
4 Followers 10 Following
Molecular Cancer Rese... @MCR_AACR
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62 Followers 54 Following Leukemia Researcher: My lab works on understanding all aspects of TP53 mutant AML and MDS. #AML, #p53, #LeukemiaStemCells, #UniversityofMinnesota
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