Shruthy Suresh (Aggarwal) @shruthy_suresh
Scientist interested in cancer @igibsocial @cancermetslab Tweets/RT my opinion Bio: https://t.co/lJ4p7599JV cancerbiolab-ssa.co.in Delhi, India Joined August 2010-
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Shruthy Suresh (Aggarwal) retweeted
A regulator of amino acid sensing links lipid peroxidation and lipid droplet-dependent antioxidant response dlvr.it/TMvWLL
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Shruthy Suresh (Aggarwal) retweeted
#authrointerview Dr. Arpan Parichha @arpan_parichha previously PhD with Prof. Shubha Tole @shubhatole lab at TIFR, Mumbai talks about his work on "How β-CATENIN helps to wire the brain’s largest communication bridge" @iScience_CP biopatrika.com/academia/resea… via @biopatrika
Shruthy Suresh (Aggarwal) retweeted
#Throwback COMMENT | KS Lee, X Su & T Huan Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics nature.com/articles/s4225…
Shruthy Suresh (Aggarwal) retweeted
Excited to share my PhD work, now out in @eLife! 🐟 We developed a mitfa:Cas9 knock-in zebrafish line for lineage-specific genome editing, enabling in vivo screening for gene function in melanocytes and melanoma cells. Read more here: elifesciences.org/articles/100257
Shruthy Suresh (Aggarwal) retweeted
My favorite part? This was driven by Miranda’s curiosity. She noticed that the cells in the tumor looked squeezed, and then followed the trail all the way to mechanism and implications.
Shruthy Suresh (Aggarwal) retweeted
Maternal stress triggers early-life eczema through fetal mast cell programming. @Nature nature.com/articles/s4158…
Shruthy Suresh (Aggarwal) retweeted
I'm thrilled to share our new study out in @NatureMedicine! We show that a blood test can estimate how aged or youthful one’s organs are and that these organ ages predict future disease and lifespan. Final paper from my PhD in the @wysscoray lab. 🧵1/12 🔗 nature.com/articles/s4159…
Shruthy Suresh (Aggarwal) retweeted
New @CellReports paper by @andrewaguirremd @DanaFarber_Hale Integrative genomic identification of therapeutic targets for #PancreaticCancer cell.com/cell-reports/f… VERY GOOD use of public datasets (DepMap, CCLE, TCGA, GTEx) to identify cell intrinsic & cell surface dependencies
Shruthy Suresh (Aggarwal) retweeted
New article alert !! In this article, we show that CTNNB1/β-CATENIN function in midline guidance cells is crucial for corpus callosum development. See thread. @shubhatole @AmritaCantSing @MirosevicSpela @IGIBSocial @TIFRScience sciencedirect.com/science/articl…
Shruthy Suresh (Aggarwal) retweeted
In @CellRepMed by @carlhjune et al @PennCancer: Clinical and molecular dissection of CAR T cell resistance in #PancreaticCancer sciencedirect.com/science/articl… This study used infused anti-mesothelin targeted CAR-T cells to identify putative TFs (SOX4, ID3) driving T cell dysfunction
Shruthy Suresh (Aggarwal) retweeted
What if treating disease meant stabilizing biology, not blocking it? We explore that idea in @ScienceMagazine with LOCKTAC molecular glues, a new class of molecules that stabilize natural interactions to either boost or block biology. science.org/doi/10.1126/sc… #mycompnay
Shruthy Suresh (Aggarwal) retweeted
Talking of @Amgen they also have cool LYMTACs: chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization & degradation nature.com/articles/s4146…
Shruthy Suresh (Aggarwal) retweeted
LYVAC is now online in Science @ScienceMagazine! LYVAC/PDZD8 mediates directional lipid transfer from the ER to the lysosomal membrane, driving lysosomal enlargement and vacuolization. science.org/doi/10.1126/sc…
Shruthy Suresh (Aggarwal) retweeted
Delighted to share our Cancer Cell paper published today, co-authored by Dr. Alexander Biederstädt @ABiederstadt_MD and Dr. Rafet Basar @rftbsr9 reporting the first genome-wide CRISPR screen in primary cord blood NK and CAR NK cells. We identify key genetic checkpoints including…
Delighted to share our Cancer Cell paper published today, co-authored by Dr. Alexander Biederstädt @ABiederstadt_MD and Dr. Rafet Basar @rftbsr9 reporting the first genome-wide CRISPR screen in primary cord blood NK and CAR NK cells. We identify key genetic checkpoints including…
Shruthy Suresh (Aggarwal) retweeted
Amazing @Nature paper by @moranamit2 & the @MDAndersonNews cancer neuroscience team. Cancer is a wound that does not heal but now we learn that injury phenomenon also extends to nerves! Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy nature.com/articles/s4158…
Shruthy Suresh (Aggarwal) retweeted
New paper out! Triplet immune checkpoint immunotherapy can reactivate highly exhausted TIM3+ CD8+ T-cells in melanoma @MoffittNews @jitcancer jitc.bmj.com/content/13/8/e…
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