Mike Mitchell @MJMitchell_Lab
Associate Professor of Bioengineering | Lipid Nanoparticles | mRNA Therapeutics & Vaccines | Drug Delivery | Biomaterials | Immunotherapy mitchell-lab.seas.upenn.edu University of Pennsylvania Joined August 2011-
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Incredible talk by @MJMitchell_Lab alumna @MagBillingsley on next gen nanoparticles for in vivo CAR T and ovarian cancer therapy at @templebioe! Bring Maggie in for a talk, she is on the faculty market and just won the prestigious @BWFUND Career Award at the Scientific Interface!
Super excited to have @MJMitchell_Lab alumna @MagBillingsley return to Philly this week! Come check out her exciting seminar @templebioe this Friday!
Super excited to have @MJMitchell_Lab alumna @MagBillingsley return to Philly this week! Come check out her exciting seminar @templebioe this Friday!
Check out our latest in @NanoLetters led by our superstar former undergrad @ryannjoseph_ (now PhD student @Harvard) on new lung CRISPR-Cas9 protein lipid nanoparticles that outperform mRNA lipid nanoparticles for cystic fibrosis applications! Link: pubs.acs.org/doi/10.1021/ac…
Excited to share a collaborative work from my time @pennbioeng with an awesome team from @MJMitchell_Lab and @ywan_wan’s group at A*STAR in Singapore!
Excited to share a collaborative work from my time @pennbioeng with an awesome team from @MJMitchell_Lab and @ywan_wan’s group at A*STAR in Singapore!
Check out our latest in PNAS @PNASNews led by former Mitchell Lab PhD students @SwingleKelsey (now Professor @Rice_BIOE) and @a_hmltn on a new circular RNA LNP vaccine platform against SARS-CoV-2! pnas.org/doi/10.1073/pn…
NIH is on track to spend its entire budget | STAT statnews.com/2025/09/12/nih…
Check out our latest in Nature Reviews Materials @NatRevMater led by @MJMitchell_Lab PhD student Andrew Hanna on high-throughput technologies for machine learning guided mRNA lipid nanoparticle design! Free access: rdcu.be/eE6GR nature.com/articles/s4157…
Another incredible @MJMitchell_Lab retreat and recharge down in Cape May filled with beach, pool, and BBQ. Be on the lookout for exciting work from the team this year on mRNA LNP biophysics, anti-aging therapeutics, cardiovascular disease, and in situ cancer vaccination!
Yesterday we opened a new home for Immunology at Penn. Part of our large vibrant immunology community will move into this amazing space. This includes our #ColtonCenter for Autoimmunity, #ImmuneHealth and more. youtu.be/Ryv2AxPtb_E?si…
House bill on HHS budget: NIH funding maintained, deep CDC cuts | STAT statnews.com/2025/09/02/hou…
America First? Not When It Comes to Your Health. nytimes.com/2025/08/24/opi… via @nytopinion
Congrats to @MJMitchell_Lab PhD student Amanda Murray @AmandaMMurray14 on her latest publication in @acsnano @ACSPublications on engineering nanoparticles for gynecologic cancer therapy! Link: pubs.acs.org/doi/10.1021/ac…
Congrats to @MJMitchell_Lab PhD student Amanda Murray @AmandaMMurray14 on her latest publication in @acsnano @ACSPublications on engineering nanoparticles for gynecologic cancer therapy! Link: pubs.acs.org/doi/10.1021/ac…
The irony of all this is that few investments match the ROI of scientific research. Every $1 invested yields major returns in jobs, innovation, and better health for our country. Cutting it guarantees economic and health losses we’ll feel for decades.
ICYMI: Finally some good news! The senate committee rejected the 40% budget cut for NIH and instead endorsed a $400 million budget increase! Science for the win.
Poor @veiseho isn’t taking the Gordon Conference election loss very well #grcbiomaterials
Poor @veiseho isn’t taking the Gordon Conference election loss very well #grcbiomaterials
New from the @kwanglab lab! 👏 Researchers with Jennifer Patten and @Karin_Wang26 show that focal adhesion kinase is an essential mechanoregulator of wound migration in #fibroblast wound closure. @templebioe 🤩 Learn more: bit.ly/4744fUi
Congrats to @templebioe @kwanglab PhD candidate Jennifer Patten for her paper, "FAK Differentially Mechanoregulates Cell Migration during Wound Closure" published in ACS Biomaterials Sci & Engr @ACSPublications ! FYI she is looking for Teaching positions doi.org/10.1021/acsbio…
How do physical forces shape disease? @Karin_Wang26’s #bioengineering lab @kwanglab at @templebioe is building tissue-mimicking platforms to decode cell behavior and develop new diagnostics. Watch her iTalks video: research.temple.edu/innovation/inn… #TempleResearch
Escaping the endosome is one of drug delivery’s biggest bottlenecks. The Mitchell Lab @PennEngineers is bending lipids to make mRNA and gene editing therapies more efficient, one nanoparticle at a time. Read more: bit.ly/3EciCJY #GeneTherapy #mRNA #LNP #Bioengineering
A new video series debuts at the iNest - iTalks features investigators bringing ideas and research to life. From @TempleUniv we are proud to present Dr. Karin Wang and Dr. Philip Dames here: research.temple.edu/innovation/inn… @Karin_Wang26 @kwanglab @templebioe @TempleResearch @TempleEng

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