Mike Mitchell @MJMitchell_Lab
Associate Professor of Bioengineering | Lipid Nanoparticles | mRNA Therapeutics & Vaccines | Drug Delivery | Biomaterials | Immunotherapy mitchell-lab.seas.upenn.edu University of Pennsylvania Joined August 2011-
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Yesterday we opened a new home for Immunology at Penn. Part of our large vibrant immunology community will move into this amazing space. This includes our #ColtonCenter for Autoimmunity, #ImmuneHealth and more. youtu.be/Ryv2AxPtb_E?si…
House bill on HHS budget: NIH funding maintained, deep CDC cuts | STAT statnews.com/2025/09/02/hou…
America First? Not When It Comes to Your Health. nytimes.com/2025/08/24/opi… via @nytopinion
Congrats to @MJMitchell_Lab PhD student Amanda Murray @AmandaMMurray14 on her latest publication in @acsnano @ACSPublications on engineering nanoparticles for gynecologic cancer therapy! Link: pubs.acs.org/doi/10.1021/ac…
Congrats to @MJMitchell_Lab PhD student Amanda Murray @AmandaMMurray14 on her latest publication in @acsnano @ACSPublications on engineering nanoparticles for gynecologic cancer therapy! Link: pubs.acs.org/doi/10.1021/ac…
The irony of all this is that few investments match the ROI of scientific research. Every $1 invested yields major returns in jobs, innovation, and better health for our country. Cutting it guarantees economic and health losses we’ll feel for decades.
ICYMI: Finally some good news! The senate committee rejected the 40% budget cut for NIH and instead endorsed a $400 million budget increase! Science for the win.
Poor @veiseho isn’t taking the Gordon Conference election loss very well #grcbiomaterials
Poor @veiseho isn’t taking the Gordon Conference election loss very well #grcbiomaterials
New from the @kwanglab lab! 👏 Researchers with Jennifer Patten and @Karin_Wang26 show that focal adhesion kinase is an essential mechanoregulator of wound migration in #fibroblast wound closure. @templebioe 🤩 Learn more: bit.ly/4744fUi
Congrats to @templebioe @kwanglab PhD candidate Jennifer Patten for her paper, "FAK Differentially Mechanoregulates Cell Migration during Wound Closure" published in ACS Biomaterials Sci & Engr @ACSPublications ! FYI she is looking for Teaching positions doi.org/10.1021/acsbio…
How do physical forces shape disease? @Karin_Wang26’s #bioengineering lab @kwanglab at @templebioe is building tissue-mimicking platforms to decode cell behavior and develop new diagnostics. Watch her iTalks video: research.temple.edu/innovation/inn… #TempleResearch
Escaping the endosome is one of drug delivery’s biggest bottlenecks. The Mitchell Lab @PennEngineers is bending lipids to make mRNA and gene editing therapies more efficient, one nanoparticle at a time. Read more: bit.ly/3EciCJY #GeneTherapy #mRNA #LNP #Bioengineering
A new video series debuts at the iNest - iTalks features investigators bringing ideas and research to life. From @TempleUniv we are proud to present Dr. Karin Wang and Dr. Philip Dames here: research.temple.edu/innovation/inn… @Karin_Wang26 @kwanglab @templebioe @TempleResearch @TempleEng
Chemical Tweak to Lipid Nanoparticles Cuts Side Effects, Boosts mRNA Potency In multiple experiments, C-a16 lipids, which contain a phenol group, outperformed LNPs used in currently available #mRNA therapeutics @Penn #nanoparticles hubs.li/Q03xVv1Q0
Now accepting applications for Career Awards at the Scientific Interface buff.ly/qobmmjP LOI Deadline: September 2, 2025 #bwfcasi
Fewer side-effects, more effectiveness. @MJMitchell_Lab's lab redesigned mRNA lipid nanoparticles using olive oil-inspired chemistry. Adding phenol groups reduces inflammation, making mRNA therapies safer & more effective. "It's a win-win," says Mitchell.
Congrats to Margaret Billingsley on winning the Burroughs Wellcome Fund Career Award at the Scientific Interface! Margaret will pioneer high‑throughput therapeutic nanoparticle platforms to combat ovarian cancer heterogeneity. bwfund.org/news/bwf-annou…
Huge congrats to @MJMitchell_Lab PhD student @ASThatte2 for winning the @Merck best poster award at #CRS2025 for his work on mRNA LNP autoimmune therapies! @CRSScience
Let’s go Coach! @MJMitchell_Lab PhD student and lab softball coach @hannahsafford_ giving a killer talk on lipid nanoparticle elasticity and mRNA delivery to the placenta as part of the Merck Grad Award final presentations at #CRS2025! @CRSScience
NIH will only accept six applications per PI per calendar year. drugmonkey.wordpress.com/2025/07/17/nih… via @drugmonkeyblog

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