Extracellular Matrix News @ExtracellMatrix
An online resource for the extracellular matrix and tissue engineering research community. Part of the @STEMCELLTech Science News service. extracellularmatrixnews.com Joined June 2010-
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🧫 Researchers optimize a method for complete decellularization of rat esophagus and to solubilize the decellularized extracellular matrix proteins to evaluate in vitro properties for scaffold fabrication. 🥼 bit.ly/4mIDUzA
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🔬 Investigators leveraged RNA-seq data to predict tumor matrix stiffness, aiming to reveal mechanical properties by molecular signatures across various cancer types. @IntJCanc | bit.ly/3KDzHzv
🧫 This review evaluates hydrogels as ECM mimics for 3D cell cultures, revisiting key ECM properties to replicate and summarize the impact of biochemical, structural, and mechanical features on cell behavior. 👉 @BioMaterSci | rsc.li/4mAcQSX
💪 This study furthered the understanding of the role of tissue mechanical properties in directing muscle cell function and provided a tool for guiding specific behaviors necessary for muscle regeneration. 👉 bit.ly/4muD89f
🐟 Researchers demonstrate that Leucine could promote #collagen deposition by inhibiting autophagy, providing novel insights into the mechanism underlying amino acid-regulated protein metabolism in vertebrates. 🔗 bit.ly/46D86WF
📊 Researchers utilized single-cell RNA sequencing, spatial transcriptomics, and a combination of in vivo and in vitro models to decode the dynamics of tumor-stroma interactions during human #LUAD progression. @oncogenejournal | go.nature.com/4mz6d3k
💡 Priyanka Verma and team at @UMich discovered that #fibroblasts from diverse fibrotic conditions display significantly reduced primary cilia length ex vivo. @J_Cell_Sci | bit.ly/3I58WU3
🤔 Researchers explored how different macroporous mesostructures affect cells, how cells, in turn, influence mechanical properties, and whether the stability and mechanical properties of bioprinted macroporous mesostructures change over time. @Uni_WUE | bit.ly/42wdtWk
💡 Dr. Juan García-Rodríguez's team at @AarhusUni_intused spatial molecular imaging to disentangle the complex interactions between cancer cells and the #TumorMicroenvironment at the invasive front of colorectal tumors. @CommsBio | go.nature.com/4gujIjm
Dr. Emilie Marhuenda's team at @QMUL identified that the talin-interacting proteins deleted in liver cancer 1, Rap1-interacting adaptor molecule, and paxillin each preferentially bind to talin at a specific ECM stiffness. @ScienceAdvances | bit.ly/4moUOTE
💓 Scientists reported that TET3 depletion in cultured cardiac fibroblasts blocked transition to myofibroblasts in response to different pro-fibrogenic stimuli. @EmboMolMed | bit.ly/3JUbhlf
Scientists including Drs. Xi Ren & Brian Frey present a glycosylation-enabled, chemoselective strategy to label and characterize newly synthesized #ECM (newsECM) proteins with augmented specificity and sensitivity. Read about newsECM. 👇 📄: bit.ly/4gq4bB5
Researchers led by Dr. Sabina Sangaletti investigated the impact of the ECM on T cell regulation in high-grade #BreastCancer patients, focusing on the relationship between ECM3 + tumors and T cell phenotypes. 🔗 Discover more: bit.ly/3HQ2eRF
This week in @EmboMolMed, researchers describe a novel mechanism whereby the DNA demethylase TET3 contributes to fibroblast-#myofibroblast transition and cardiac #fibrosis. ❤️ 🔗 Check it out: bit.ly/3JUbhlf
Using visible-light-mediated #photochemistry, Dr. @ClaudiaLoebel and colleagues induced local crosslinking and stiffening of #ECM proteins within in vivo mouse and human lung tissue. 🫁 🔗 More in @NatureMaterials | go.nature.com/4nsvL2Z
Epigenetic changes, including DNA methylation and histone modification, can alter the normal immune and stromal cells in the #TME. This may enhance the effect of cancer driver mutations, report Drs. @hari_E_iyer16 and Ashani Weeraratna. 🔗 go.nature.com/42lxkr4
📢 A novel strategy integrating collagen sequence optimization and microbial prolyl-4-hydroxylase screening was developed to enable efficient production of triple-helical rhCol in Komagataella phaffii. 🔗 bit.ly/4nA1pM7
👇 Check out the signaling pathway that promotes #ECM degradation in primary human hepatic stellate cells, which is dependent on the activation of protein kinase Cα and the induction of matrix metalloproteinase 1! @UCSF @ScienceTM | bit.ly/4p6ZBM1
🧠 Researchers at @CCLRI identified TBK1 as a critical signaling molecule enriched and activated in tumor-associated macrophages of BCBM tumors, playing an indispensable role in BCBM development and metastatic outgrowth in the brain. @PNASNews | bit.ly/4g4ZPiH
Alberto Elosegui-Arto... @AEloseguiArtola
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Sailesh Palikhe @saileshpalikhe
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Nicholas A. Peppas @NPeppas
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8K Followers 666 Following We engineer biomaterials - hydrogels, HA, biofabrication. Tweets by JB and group members. @pennbioeng @BioFrontiers @CUEngineering
Nature Biomedical Eng... @natBME
52K Followers 56 Following News from the editors of Nature Biomedical Engineering, a journal for researchers, engineers and clinicians interested in human health. Launched in Jan 2017.
Eileen Gentleman Lab @GentlemanLab
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Dr Brendan Harley is ... @Prof_Harley
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ASMB @amsocmatbio
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Dr. Edna Cukierman, P... @ednacukierman
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Leda Lacaria @Leda_Lcr
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Munta @Munta04
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Rebecca Irwin @Becka_Irwin_
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Gideon Nsubuga (גד�... @GideonNsubuga
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Lucia Borriello @luciaborriell
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Moritz Mall @MoritzMall
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Steven White @cardiacpathmd
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Daeun Jeong @DaeunJeong10
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Christine Mayr @Mayr_Christine
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135 Followers 45 Following Department of Orthopaedics and Traumatology, The University of Hong Kong
Sayan Chakraborty @sayan101284
165 Followers 359 Following Our lab focuses on the microenvironmental regulation of extracellular matrix protein(s) promoting cancer progression and wound healing
Zebrafish Dev. Neurob... @ZebrafishGroup
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Dr. Pilar de la Puent... @delapuente_lab
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Gianluca Matteoli @gmatteoli1978
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Vermot Lab @VermotLab
1K Followers 434 Following We study mechanotransduction in heart valve morphogenesis, blood vessel formation & left-right asymmetry in zebrafish @ImperialBioeng [email protected] 🦋
Giulia Boezio @Giulsboezio
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2K Followers 90 Following Our lab studies #development #regeneration #geneticrobustness @mpi_hlr. The account is run by various lab members.
Manisha Singh @manisha_s1ngh
253 Followers 544 Following Bio/Fluid-Mechanics, Materials, System Design & Soft Robotics | Cardiac Simulators, Heart Valve & Device Engineering | Postdoc @MIT
Miguel Angel delPozo @madelpozo67
7K Followers 1K Following Dad, Scientist & Medic (Immunologist). @EMBO Member #mechanobiology #atherosclerosis #immunECM @CaveoLab @CNIC_CARDIO ...I´m taking a ride with my best friends♫
Felix_Gunawan 🏳️... @GunawanLab
507 Followers 307 Following Assistant Professor @UofTCellSysBiol. Group Leader @uni_muenster. Cardiovascular morphogenesis & plasticity.
Tatsuya Tsukui @TatsuyaTsukui
555 Followers 168 Following Assistant Professor at @UCSF. Pulmonary fibrosis | Fibroblast | Tissue injury and remodeling | Immunology
Yuki. Taniguchi @Yuki_BMresearch
80 Followers 263 Following A researcher for ECM and related molecules, also having the interest in kidney diseases, especially IgA nephropathy. All tweets are my personal comments.
Maria Alcolea @MariaPAlcolea
1K Followers 533 Following Group Leader at the Cambridge Stem Cell Institute @SCICambridge. Interested in epithelial cell fate plasticity, stem cell biology and early tumorigenesis.
Jim Woodgett @jwoodgett
10K Followers 350 Following Biomedical researcher at #LTRI: signaling, cancer; @[email protected] @jwoodgett.bsky.social He/Him #TerryFox https://t.co/c02NBnBblM Joined 2010 (verify below).
Owen Clarkin @OwenMClarkin
176 Followers 331 Following Principle Investigator of Dublin City University Biomaterials Research Group Views here my own not DCU's. Re-tweets not an endorsement.
Sahil Kamboj 👨�... @iSahilKamboj
687 Followers 1K Following Postdoc @KCLImmunoMicro | Doctorate from @UniversiteCergy and @warwickuni | BS-MS @IISERMohali
Chao-Wei Chen @willhyper
26 Followers 125 Following semiconductor, defect optical/ebeam inspection Medical imaging, OCT, Fourier optics, diffusion optics, mathematical optimization Automation, Python, Clojure
Frauke Graeter @graeter_mbm
690 Followers 119 Following
Evan Scott @ProfScottBME
2K Followers 1K Following Kay Davis Professor of Biomedical Engineering & Microbiology-Immunology at Northwestern University; @NorthwesternU; @NU_McCormick
Jordy - ジョルデ�... @iDeJordy
101 Followers 121 Following Regenerative medicine spine researcher. Expat in Japan. Following global-politics. Thinks Green is the solution! 🇪🇺 #iameuropean
Anna Guller 🇺🇦�... @anna_guller
855 Followers 2K Following 🇺🇦🇦🇺 Experimental pathologist & biophysicist. Tissue engineering, nanoresearch, and imaging. Regeneration, fibrosis and cancer. MQRF @Macquarie_Uni
Aubrie Stricker @aubrie_stricker
106 Followers 524 Following PhD candidate at Vanderbilt | Cell and Development | @PageMcCawLabTrends for United States
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Joan Chang
@tranejoan
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