Yichi (Tony) Zhang @tony_zhang_phd
Believer of serendipity in science & life. Canadian, Bball fan. PhD w. Eric Olson @ UTSW, K99 awardee and former Damon Runyon fellow w. Matt Vander Heiden @ MIT Somerville, MA Joined January 2021-
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Happy birthday to the one and only Eric Olson @Transactivator on hosting a scientific symposium, party, and reunion for the Olsonites as only he can. It’s truly an honor and a privilege to be part of this family. Rock on! I can’t wait to see you all again for Myolife 50!
🚨New paper out in Circ Res! Congrats to 1st author DR @OmarBritoStrada & the team👏🏼Here we show DWORF gene therapy boosts cardiac calcium handling, enhances mitochondrial energetics, & protects against heart failure progression🫀💪🏼 Read it here 😍👇🏼 doi.org/10.1161/CIRCRE…
Fantastic. The momentum among private funders to disallow journal fees continues to build. @NIH should follow suit. “In the coming 1-2 years, HHMI will seek to replace APC payments from HHMI lab budgets with centralized support of publisher service fees, including transparent…
Fantastic. The momentum among private funders to disallow journal fees continues to build. @NIH should follow suit. “In the coming 1-2 years, HHMI will seek to replace APC payments from HHMI lab budgets with centralized support of publisher service fees, including transparent…
Excited to share our new preprint—the main project of my postdoc in the Kaelin lab! Blocking HIF2 doesn’t just slow tumors—it can reverse cachexia and hypercalcemia in kidney cancer. In the OSRC-2 model, HIF2 inhibition restored weight, preserved fat/muscle, and rescued survival.
Molecular subtypes of human skeletal muscle in cancer cachexia nature.com/articles/s4158…
wow. stop what you're doing and read this paper. 🤯cell.com/cell/fulltext/…
Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of @MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be.
Congratulations to Eric Olson, Ph.D., founding Chair and Professor of Molecular Biology @UTSWMedCenter, on being selected to receive the Louisa Gross Horwitz Prize for groundbreaking research into Duchenne muscular dystrophy. bit.ly/46lL9Z8
🔬 Published in Nature Cell Biology, @WalterWChen1 and his collaborators have identified PEX39, a human protein needed for assembling peroxisomes. This is the first such protein discovered in more than 20 years. Read more: bit.ly/4n5wmHs @CRI_UTSW #CellBiology
Great lab bonding at our 2025 lab retreat. A good mix of scientific discussion and lab fun. I'm so grateful for such an inspiring and energetic lab!
Fantastic MVH lab retreat featuring all you can eat buffets, lab FIFA, inspiring talks from Matt and others, s'mores by the firepit, and a suprise DJ set by @EdreesRashan aka Rich Media and MyoDJ. Lab retreats are special because we all learn more about each other as people
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. nature.com/naturecareers/… Please repost!
Can’t wait to see the transactivators again next month for the Myo-life symposium!
Can’t wait to see the transactivators again next month for the Myo-life symposium!
I’d say most PhD students don’t even have ONE of these !
I’d say most PhD students don’t even have ONE of these !
What is the endgame for ANGPTL3? $LLY in their website update just added VERVE-201 alongside the PCSK9 editor VERVE-102 in their list of phase 1 programs. With ANGPTL3 the siRNA results ($LLY, $ARWR) have been quite different from the ASO data (Ionis). It'll be intriguing to…
We’re deeply saddened by the passing of David “Davo” Mangelsdorf, Ph.D., Professor and Chair of Pharmacology at UTSW, whose work on orphan nuclear receptors transformed our understanding of metabolism and endocrinology and inspired countless scientists. bit.ly/47jN4hK
Everyone needs to hear this…
A simple benchmark. Most people can understand it. No PhD-level intelligence needed.
I spent 1.5 years at MIT designing a new undergraduate program in Genetic Engineering. One of our theses in designing that program (which I’ll share more about soon; I'm writing a long essay about it) was that undergraduate students could be trained to be excellent genetic…
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Teng Gao @tGaoTeng
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