Trivedi Lab @trivedilab
The research goal of the Trivedi lab is to identify cellular processes and regulatory mechanisms involved in human cardiac and vascular diseases. profiles.umassmed.edu/display/130458 Worcester, MA Joined August 2017-
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Trivedi Lab retweeted
Could metformin reduce structural heart disease? ASCI member @trivedilab & team @UMassChan find epigenetic changes in nuclear DNA aberrantly activate mitochondria, causing aortic valve stenosis, with improvement by metformin in mice: insight.jci.org/articles/view/… The image shows…
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Outstanding collaborative work by Tim Cashman et al - Epigenetic dysregulation of energy homeostasis drives aortic valve stenosis that is treatable with metformin insight.jci.org/articles/view/… @UMassChan @umassmemorial @UMass_Medicine @JCI_insight @the_asci @endothelialnews
Trivedi Lab retweeted
Join our collaborative team of investigators! The Division of Cardiovascular Medicine in the Department of Medicine at UMass Chan Medical School is now accepting applications for a tenure-track faculty position. Learn more and apply: tinyurl.com/4a7pedsr
Check out a new review series: Lymphatic System in Organ Development, Function, and Regeneration @UMassChan @UMass_Medicine @CircRes ahajournals.org/doi/10.1161/CI… Outstanding reviews from @NU_Lymphatics @CaronLabUNC @PetrovaLab @ulvmar_maria @EShelton24 @annetkiraboc1 & Valentina Kon!
Very excited to share our recent work published as the cover story @JCI_insight insight.jci.org/articles/view/… Fantastic collaboration @UMassChan @umassmemorial @UMass_Medicine @UMassCardio @vascularbiology
Trivedi Lab retweeted
#Cover: Pathological activation of MAPK causes lymphangiectasia treatable with ravoxertinib: buff.ly/3RFn7y1 Image: H&E-stained pathological human tissue section that shows lymphangiectasia. @trivedilab @UMass_Medicine #Development #VascularBiology
Checkout a new comprehensive review series on vascular and lymphatic malformations @CircRes @AHA_Research @vascularbiology @EVB_Org @endothelialnews ahajournals.org/doi/10.1161/CI…
Our recent manuscript showing YAP1 drives epithelioid hemangioendothelioma is published as the Cover story of July 2021 issue of @atvbahajournals @UMassMedical Wonderful collaboration with @UMassMedMCCB @umassmemorial ahajournals.org/doi/10.1161/AT…
Our recent study by Roy Jung et al @trivedilab @UMassMedical @GSBS_UMassMed @UMass_Medicine show "Sustained Activation of #Endothelial #YAP1 Causes #Epithelioid_Hemangioendothelioma" @atvbahajournals Wonderful collaborators @umassmemorial @UMassMedMCCB ahajournals.org/doi/10.1161/AT…
Recent work from our lab @trivedilab @UMassMedical @UMassMedCancer @GSBS_UMassMed is published as Cover in July issue of @JExpMed Fantastic collaboration with @umassmemorial
Recent work from our lab @trivedilab @UMassMedical @UMassMedCancer @GSBS_UMassMed is published as Cover in July issue of @JExpMed Fantastic collaboration with @umassmemorial
Harish Janardhan in our lab @trivedilab @UMassMedical show #KRAS or #BRAF mutations cause #hepatic #vascular cavernomas treatable with MAP2K-MAPK1 inhibition @JExpMed #vascularbiology #hemangioma #endothelialcells doi.org/10.1084/jem.20…
Trivedi Lab retweeted
This study by Harish Palleti Janardhan, @trivedilab, et al. @UMassMedical @GSBS_UMassMed @vascularbiology demonstrates endothelial KRAS or BRAF gain-of-function mutations as a causal mechanism for hepatic vascular cavernomas bit.ly/3dIqnEY
A recent study from our lab @UMassMedical @GSBS_UMassMed shows Hdac1/2 silence cryptic transcription to promote mitochondrial function and energy production in heart @ScienceAdvances Awesome collaboration with @chaynes329 advances.sciencemag.org/content/6/15/e…
Establishment and maintenance of blood-lymph separation. - PubMed - NCBI ncbi.nlm.nih.gov/pubmed/30758642
JCI - Hdac3 regulates lymphovenous and lymphatic valve formation jci.org/articles/view/…
Hdac1/2 are essential for neural crest proliferation, pharyngeal arch development and craniofacial morphogenesis. - ncbi.nlm.nih.gov/pubmed/28791750
HDAC3-mediated epigenetic silencing of TGF-β1 is required for normal heart development - NCBI ncbi.nlm.nih.gov/pubmed/26420484
Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis. - PubMed - NCBI ncbi.nlm.nih.gov/pubmed/2456586…
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