udaibanerji @udai_banerji
Passionate about Molecular Cancer Pharmacology and the need to think out of the box. Joined July 2016-
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Medicine intersects with physics. Targeting tumours with ultrasound and microbubbles to increase delivery of standard chemotherapy in tumour tissue. Achieving proof of concept in metastatic CRC (NCT04021277) Abst 6221 #AACR2024 @ICR_London @TheRMH @CRUKConvergence @ECMC_UK
New frontiers in exploiting stroma for therapy. FAP directed precision medicine. Phase I of AVA600 showing tolerability, plasmas/tumour PK and clinical proof of concept response in FAP high tumours. Abstract CT188 #AACR2024 @ICR_London @royalmarsdenNHS @ECMC_UK
Messing with (cancer cell) stress. PK-PD and toxicity of the dose escalation cohort of NXP800 (NCT05226507) Abst CT111 at #AACR2024. Target engagement confirmed, next steps to evaluate efficacy in ARID1A mutated tumours. @ICR_London @TheRMH @ECMC_UK @RMresearch_
First report on the Phase-1 Clinical Trial (ASTEROID) by DDU-IIT team. Looking forward to Crescens' Oral Presentation at AACR on 8th April 2024
Fantastic to be reunited with Rachel Lau during PhD graduation function #ICRGrad Proud she is blazing her way through her 1st post doc. Her work on CAF proteome/secretome opened many research avenues. The future is 🌞! @ICR_London @royalmarsdenNHS @NIHRresearch
Crucial to expose next generation of university students to careers in life sciences and clinical trials.Proud to bring work experience students together from academia,charities and pharma.@ICR_London @royalmarsdenNHS @CR_UK @ECMC_UK @NIHRresearch #resilientlifescienceworkforceUK
The future is bright! Clinical Fellow Dr Alvaro Garces sucessfuly defended his PhD. Cancer evolution in ovarian cancer can be can be understood and possibly exploited.... @ICR_London @royalmarsdenNHS @BanerjeeSusana @AndreaSottoriva @trevoragraham @CR_UK
Optimizing Optimus. Change in the way we do phase I trials is necessary and we have to do so thoughtfully... pubmed.ncbi.nlm.nih.gov/38129533/ @ICR_London @royalmarsdenNHS @ECMC_UK @ICR_DDU_IIT
Stroma, the new frontier. Elegant papers
The heart and soul of our research institution. Super-intelligent caring people who chose to do this job to make a difference to cancer patients. 👏👏👏 @ICR_London @royalmarsdenNHS @ECMC_UK @CR_UK @NIHRresearch
The heart and soul of our research institution. Super-intelligent caring people who chose to do this job to make a difference to cancer patients. 👏👏👏 @ICR_London @royalmarsdenNHS @ECMC_UK @CR_UK @NIHRresearch
Very interesting but frightening read, pointing to heritable rewiring of the epigenome as a player in drug resistance. We will need to rethink our current strategies of treating patients with metastatic disease pubmed.ncbi.nlm.nih.gov/37331179/
Very interesting but frightening read, pointing to heritable rewiring of the epigenome as a player in drug resistance. We will need to rethink our current strategies of treating patients with metastatic disease pubmed.ncbi.nlm.nih.gov/37331179/
An important message for early phase cancer clinical trialists. We ask for a lot from our patients who selflessly give up their time. 🤔Think before you ask for more visits, investigations, or questionnaires in your protocols. @ICR_London @royalmarsdenNHS @ECMC_UK @NIHRresearch
An important message for early phase cancer clinical trialists. We ask for a lot from our patients who selflessly give up their time. 🤔Think before you ask for more visits, investigations, or questionnaires in your protocols. @ICR_London @royalmarsdenNHS @ECMC_UK @NIHRresearch
Lot to learn from phase I trials. The jigsaw of evidence from the pharmacological audit trail studying ATR inhibitors pubmed.ncbi.nlm.nih.gov/37934611/. Stellar job of an investigator initiated trial from colleagues @ICR_London @royalmarsdenNHS @drmagnusd @ECMC_UK @NIHRresearch @cruk
📜👩🎓Applications are now open for our 2023/24 fully-funded #PhD studentships. Check out our PhD projects and apply⬇️⬇️ icr.ac.uk/studying-and-t…
📜👩🎓Applications are now open for our 2023/24 fully-funded #PhD studentships. Check out our PhD projects and apply⬇️⬇️ icr.ac.uk/studying-and-t…
#TargetingRAS Presenting at an amazing RAS focussed meeting of academia/industry/patient advocacy groups. Science is moving at warp speed (inhibitors of G12C, G12D, pan RAS, Ras interactors/effectors), need to translate this to patient benfit ASAP. @ICR_London @royalmarsdenNHS
Could not agree more,smoking kills not just due to cancer but also strokes and heart attacks. Nicotene is addictive. Beware of free samples of buccal tobacco pouches being handed out free in music festivals, the tobacco industry is still looking to increase its base. #smokefreeUK
Could not agree more,smoking kills not just due to cancer but also strokes and heart attacks. Nicotene is addictive. Beware of free samples of buccal tobacco pouches being handed out free in music festivals, the tobacco industry is still looking to increase its base. #smokefreeUK
Now that (most of the) low hanging fruit have been picked, is time to look for anticancer targets elsewhere? Fantastic work from past PhD student and now post-doc @RLau_ICR . Peek into the CAF proteome... pubmed.ncbi.nlm.nih.gov/37481068/ @ICR_London @royalmarsdenNHS @cancerBRC @CR_UK
Cancer evolution is well documented. So what are we going to be doing about it? Multidisciplinary conversations needed... pubmed.ncbi.nlm.nih.gov/37331179/ @ICR_London @royalmarsdenNHS @cancerBRC @ECMC_UK @CR_UK @trevoragraham @NPortaStat
Elegant explanation of evolutionary concepts of adaptive therapy. Current focus on targeted treatment but one day we be able to deconstruct a few complex chemotherapy combinations to improve survival and certainly improve QOL....
Elegant explanation of evolutionary concepts of adaptive therapy. Current focus on targeted treatment but one day we be able to deconstruct a few complex chemotherapy combinations to improve survival and certainly improve QOL....
Refresusted (refreshed+exhausted) after working with young investigators and faculty in the Methods in Clinical Cancer Research Workshop 2023. Great new ideas and energy in cancer research. #MCCR2023 @myESMO @EORTC @AACR @ICR_London @royalmarsdenNHS
The ICR @ICR_London
24K Followers 2K Following The Institute of Cancer Research is making the discoveries that defeat cancer. We're a top UK academic research centre, a postgrad college, and a charity.Adam Sharp @AdamSharpMedOnc
4K Followers 3K Following Academic medical oncologist. Interested in biology, prostate cancer and drug development. Husband/Dad/Sport. Views my own and no specific advice/DMs.Rossanese Lab @TEMT_ICR
836 Followers 801 Following Target Evaluation and Molecular Therapeutics Team @ICR_LondonOphidian @Ophidian18
3K Followers 106 Following Scientist, Conservationist, Traveller, Investor, very lucky Husband & super proud Dad of two wonderful strong independent grown-up people. - oh and Golf nut.Vivek Subbiah, MD @VivekSubbiah
34K Followers 2K Following Chief, Early-Phase Drug Development|@SarahCannonDocs #Oncologist, #Phase1trials, #PrecisionMedicine. Tweets=My own.Cellar boy @boy_cellar
1K Followers 387 Following Derivatives trader. AIM investing with a focus on Biotech.Science and Innovatio.. @CRUKresearch
25K Followers 2K Following We're here to support our broad cancer research community of 4,000 scientists and clinicians. For general Cancer Research UK news & fundraising follow @CR_UKAvacta @avacta
8K Followers 263 Following We develop safe and efficacious drugs and high performance diagnostics, based on our proprietary Affimer® and pre|CISIONᵀᴹ platforms.Charles Swanton @CharlesSwanton
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698 Followers 544 Following The Guettler Lab @ICR_London studies cell signalling using biochemistry, structural biology and cell biology.Jon Lim @DrJonLim
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503 Followers 612 Following AIM Investor rather than trader! Positions in #EUA #AVCTThe ICR @ICR_London
24K Followers 2K Following The Institute of Cancer Research is making the discoveries that defeat cancer. We're a top UK academic research centre, a postgrad college, and a charity.Adam Sharp @AdamSharpMedOnc
4K Followers 3K Following Academic medical oncologist. Interested in biology, prostate cancer and drug development. Husband/Dad/Sport. Views my own and no specific advice/DMs.Rossanese Lab @TEMT_ICR
836 Followers 801 Following Target Evaluation and Molecular Therapeutics Team @ICR_LondonVivek Subbiah, MD @VivekSubbiah
34K Followers 2K Following Chief, Early-Phase Drug Development|@SarahCannonDocs #Oncologist, #Phase1trials, #PrecisionMedicine. Tweets=My own.Charles Swanton @CharlesSwanton
15K Followers 819 Following Francis Crick Institute and UCL Hospitals @CR_UK Cancer Evolution and Genome Instability Lung Oncologist Air Pollution and Drug Resistance Fair Weather 🚴ICR-CTSU @ICR_CTSU
1K Followers 323 Following Clinical Trials and Statistics Unit @ICR_London. Translating cutting-edge science into quality clinical trials that can transform cancer care.The Royal Marsden NHS.. @royalmarsdenNHS
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282 Followers 108 Following Interdisciplinary research to predict cancer evolution & improve treatment. @trevoragraham @BezziLab_ICR @PaedCancerEvol @AndreaSottoriva @nearlobey @luisglszPedro Ballester @pjballester
1K Followers 863 Following Royal Society Wolfson Fellow & SL at Imperial College London. Editor at @OxfordJournals Briefings in #Bioinformatics, @Nature_NPJ #PrecisionOncology, + others.Alex Georgiou @Alex__Georgiou
137 Followers 179 Following Medical Oncology Consultant at Guy’s and St Thomas’ and King’s College Hospital (PRUH) London, Honorary Senior Lecturer King’s College London @GSTTnhsFunctional Proteomics @Proteomics_ICR
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227 Followers 147 Following We are the Investigator Initiated Trials team within the @ICR_London Drug Development Unit. We sponsor innovative Phase I trials of novel anti-cancer agents.Susana Banerjee @BanerjeeSusana
1K Followers 71 Following Consultant Medical Oncologist, Royal Marsden, Team Leader ICR All views my ownChristina Yap @ChristinaBYap
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515 Followers 518 Following Medical Director @Amgen. Early Drug Development. Tweets are my own.NIHR Royal Marsden BR.. @RMresearch_
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33K Followers 303 Following Nature Cancer is a journal dedicated to publishing the latest advances across all areas of cancer research.Andrea Sottoriva @AndreaSottoriva
4K Followers 377 Following Professor of Cancer Genomics & Evolution Head of Computational Biology Research Centre @ Human Technopole, MilanAnguraj Sadanandam @LabSadanandam
1K Followers 1K Following Developed first time PDAC,PanNET, CRC subtypes;precision medicine;machinelearning;diagnosis;preclinical trial;Global Oncology; digitaltwin;entrepreneur (my own)Chris Lord @lordoflard
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2K Followers 2K Following Head of #Sarcoma Unit at @royalmarsdenNHS. Team Leader of Sarcoma Trials for @ICR_London. All personally tweeted views are my own.Dr Elizabeth Coker @LizzieCoker
2K Followers 3K Following Data scientist modelling drug combinations to improve patient outcomes. Views my own, she/her 🇪🇺Journal of Clinical O.. @JCO_ASCO
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40K Followers 250 Following The latest clinical diagnostic, treatment & personalized medicine advances & more from Nature Reviews Clinical Oncology, a reviews journal. Tweets by the eds.Joining us at #CRUKBrain24 is Juanita Lopez whose research focusses on immune-responses in #Cancer to develop novel treatments including the first-in-brain 5G molecular hypotheses testing platform. Hear more from Juanita 👉 bit.ly/3wecdd9 @royalmarsdenNHS | @ICR_London
Once again I can only assume this is how oncology drugs get their names
FDA Approves Nogapendekin Alfa Inbakicept Plus BCG for BCG-Unresponsive NMIBC onclive.com/view/fda-appro… via @OncLive
▪︎Avutometinib/ defactinib maintains exceptionally high tumor response rates in heavily pretreated patients with recurrent LGSOC, similar TRAE incidence in 1-3 or ≥4 prior LOT. ▪︎KRAS mutation not necessary for response (m/wt) ▪︎Consider moving this trial to the frontline
Today, The Royal Marsden launched its Five-Year Clinical Strategy, in partnership with @ICR_London. For more information about new strategy, and to see our achievements from the past five years, visit: bit.ly/4aVCAno
@ElizSMcKenna @danwpaterson @VivekSubbiah @udai_banerji @VerastemOncolog @Mirati @BrunaPellini @DrShubhamPant @KRASKickers @StephenVLiu Interestingly, on-target activity of MRTX0902 can be monitored non-invasively as a surrogate for tumor tissue using whole blood. Co-administration of MRTX0902 with avutometinib demonstrated increased efficacy and was well-tolerated with no adverse side effects in mice. 🎯 #KRAS
The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading. 🔻 doi.org/10.1158/1535-7…
Super thanks to @CharlesSwanton for taking the time out to visit us minions at #BTOG24 and update us all on the amazing work going on in the preclinical space. The talk was stellar
⭐️📍 Before heading to @AACR #AACR24, celebrating an ASCO @ASCO Announcement! 👉🏼Congrats to @IshwariaMD earning the Fellow of ASCO recognition #FASCO ! 🎉 Her dedication to clinical trials access & oncology professional wellbeing is second only to her ability to…
Join us in congratulating the following members on earning the Fellow of ASCO (FASCO) distinction this quarter! We're grateful for your extraordinary volunteer service, dedication, and commitment to ASCO. More about FASCO: brnw.ch/21wIvxP
Registrations are still open for our upcoming event held at the @ICR_London exploring our latest research into breast and gynaecological cancer. To register please visit: cancerbrc.org/news-events/ev… #breastcancer #gynaecologicalcancer #CancerResearch
Don’t underestimate the beyond project impact of fellowships. @acmedsci @ProstateUK @NIHRresearch @The_MRC @PCF_Science @wellcometrust have supported me over the past 10 years. Thank you does not seem enough.
Dr Adam Sharp received a clinical lectureship grant in partnership with @ProstateUK + @acmedsci in 2015 🤝 His work explored how the androgen receptor 'shapeshifts' to evade hormone therapy in #prostatecancer, identifying new treatment targets Read more: bit.ly/3TJwgIG
First report on the Phase-1 Clinical Trial (ASTEROID) by DDU-IIT team. Looking forward to Crescens' Oral Presentation at AACR on 8th April 2024
The ECMC Programme Office are at the pan-Scotland ECMC meeting today. Great to hear about all the exciting work in the region and the focus on equitable trial delivery! @ECMC_Glasgow @ECMC_UK Edinburgh
Very honoured to have received the CRUK 2024 Horizons Explorer Recognition Award for our p110 PI3K activator work with Roger Williams @MRC_LMB - Also what are the odds to have received the (p)110 cloakroom ticket too? @CRUKresearch @CR_Horizons @uclcancer bit.ly/4akaj9G
Our first ever Student Symposium, an effort to build future clinical trials workforce, provided an opportunity to our sandwich year students, students from academic / industry partners and the HRA to gain an insight into our site functions, site facilities and the HRA processes.
@TomasNugent @Decscfc1990 @AACR @udai_banerji @ICR_London @royalmarsdenNHS @avacta #AVCT is redefining #oncology. Realisation will kick in at some point. #AACR #AACR24
Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancer dlvr.it/T3zLZH
Thank you
Did an interview with the daily express this week arranged by PCUK. It was published today, hope it makes a difference and raises awareness 😀🤞👍