whyes @whyeszhu
Reborn. 原ID @whyes . 肝脏外科医生,特别关注肝癌治疗进展。 谢绝将 **所有** 推文转载到其他网站。 @[email protected] whyes.org People's Republic of China Joined December 2018-
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看了一下将要在6月初召开的 #ASCO24 会议的报告标题,发现肝胆肿瘤领域又是小年。两个肝癌术后辅助治疗的 III 期研究取消了在会议上公布结果,只有一项晚期肝癌的免疫治疗的研究(CheckMate-9DW)会公布结果😐
过去的一年里你尝试了 6 个闭源大模型,17 个开源大模型,给 5 个 AI 服务分别付了 20 刀。 问了 40 次你好,你是谁?在你的问题里鲁迅一共暴打了 72 次周树人,树上的 10 只鸟被射下来 28 次,小红书冰丝内裤文案被写了 9 次。 画了 30 次一只可爱的猫在太空,写了 100 次快速排序。请再接再厉。
儿子对创作者比较友好,前阵子看我在电视上给一个油管视频点赞,问我是干什么的,我告诉他是给好看的视频竖大拇指点赞。现在他看到好看的视频,都要让我帮他操作点赞的动作。
在最近的两个临床试验中,礼来公司的双靶点减肥药替尔泊肽被证明可以改善睡眠呼吸暂停,可能成为第一个治疗睡眠呼吸暂停综合征的药物。
In the ALINA phase 3 trial of adjuvant treatment for patients with resected ALK-positive non–small-cell lung cancer, disease-free survival at 2 years was 93.6% with the ALK inhibitor alectinib and 63.7% with standard chemotherapy. Full trial results: nej.md/3VUzf3M
见证了一个豪斯时刻。18岁的病人,因病卧床2年,两个月前开始电解质紊乱,来我院一通检查,无解,电解质补充量越来越大,指标也不见好转,动员家属去协和了。在协和又住了小一个月,查不明白,直到前两天,从他血里查出来高浓度的利尿剂,并且在他自己长期吃的保健品药瓶里,发现了不属于那里的药。
#1/8 Multicenter P1/2 trial of a personalized neoantigen vaccine + anti-PD1 (pembro) in 2L #HCC presented at #AACR2024 & published in @NatureMedicine ➡️nature.com/articles/s4159… ORR 31%,⏫historical control of pembro monotherapy (~17%) Details below:
Another MAJOR development in GU Cancers presented at #EAU24. Nivolumab improves OS in bladder cancer ! This is major. First IO/PD1 to prolong OS in adjuvant urothelial cancer —congrats to the field, the patients, @MattGalsky and all. Major milestone! @OncoAlert @OncoBellmunt…
Another MAJOR development in GU Cancers presented at #EAU24. Nivolumab improves OS in bladder cancer ! This is major. First IO/PD1 to prolong OS in adjuvant urothelial cancer —congrats to the field, the patients, @MattGalsky and all. Major milestone! @OncoAlert @OncoBellmunt…
China’s NMPA Grants Priority Review to Sintilimab Plus Fruquintinib in pMMR/Non–MSI-H Advanced Endometrial Cancer #gynsm #oncology onclive.com/view/china-s-n…
才来扬州的时候,听着小区里面每晚都有的竖笛声、二胡声 觉得扬州人真是多才多艺 在家里还要研究乐器 直到我家娃上了小学……特么的这是学校的必选课……
orange.ai @oran_ge
85K Followers 707 Following AI Researcher&Advisor |Think in public | Passionately Curious |Building Good Karmayihong0618 @yihong0618
63K Followers 3K Following 喜欢王小波,大概我们能成为朋友。 我的 2024 https://t.co/HfDF6oduB7 我的 2023 https://t.co/QyV8PiZmOY 我的2022 https://t.co/NLYTn7xtta 我的 2021 我的 2020陈少举 (🦣 @ch.. @chenshaoju
60K Followers 1K Following 构成:30%生活,20%ACG,20%技术,15%查证,10%股市,5%政治。 PGP:https://t.co/tE5FodMBh0, Bitcoin:1DvdCDjUJ4bnqDgyzTAQ2xabw6ChRnQ9Sy, BitMsg:BM-GuKfKkQoZEX7Cmmg5ifTwnyhdihc9DnR。衛斯理 @imwsl90
44K Followers 7K Following 产品经理:主要方向出海、跨境支付、SaaS | 前程序员: iOS/JS/PHP | 博客:https://t.co/LB6NMaM0wb | Tg: https://t.co/TJY88FJKQ3 | Tg Channel: https://t.co/7fdzedpBMT | 提供 group as a service 陪聊服务 私信加 Vluolei @luoleiorg
45K Followers 1K Following 💻 Front-End Developer / 🎬 YouTuber https://t.co/7g47VdNMnN / 🏦 Investing and Learning 📝 Blog https://t.co/6ucNiJ2gyg / 👨🚀 More info at https://t.co/smbFyIb6HcHuihoo灰狐 @huihoo
19K Followers 2K Following 自由软件计算机科学、数学物理学音乐爱好者,欢迎大家加入灰狐数学物理计算科学星球,成为会员,支持帮助灰狐更多学习研究与交流分享 ... https://t.co/vby1F6q5qQ𝘁𝗮𝗿𝗲𝘀�.. @taresky
31K Followers 702 Following 📊 Crypto 服务员 | ✏️ 兼职 PM | 🏄 数字游民 | ⚙️ 持续折腾 | 💸 善于花钱 🔗 AffHub 优惠返佣 https://t.co/ZuppFmiega 🌟 自动放贷机器人 @lendingcat / https://t.co/HTHpOfARUZSpiderman @Spiderman_yogur
28 Followers 58 Following游走于世间的蜀.. @enpaul520035119
5 Followers 36 Following 爱好美食 喜欢旅游 对人世间一切美好都有兴趣!日常上班 休息则会一个行李包 一部手机游走天下!小学开始,同学就给我取了外号:大屌哥💪Solitary @Deirdre1123300
48 Followers 1K Following I am a lively and cheerful girl who would like to meet a good friend.. @theMilkyWay___
7 Followers 305 Followingflyfish @flyingfish22333
6 Followers 32 Following云泥天渊 @1207448560
14 Followers 238 Followingclaraesn @claraesn11
3 Followers 174 Followingbreak ; @R3M0v3Sec
123 Followers 1K FollowingBrian @Brian800267799
0 Followers 104 FollowingMLIN23 @AKG00000
2 Followers 272 FollowingLynn @xiaohuzi130
8 Followers 167 Followinglwx @lesywix
40 Followers 643 Followingshangyishi @shangyishi
141 Followers 274 FollowingFafnir @wangpen00376511
29 Followers 346 FollowingOsita @es_zeng
40 Followers 176 Followingkevin @KevinMemeda
3 Followers 56 Followingxinli zhang @xinlizhang3
17 Followers 126 Followingstillsilent @stillsilent7
115 Followers 434 FollowingMk @Mk48107617
61 Followers 418 FollowingSoloman @Solomanxxx
72 Followers 270 FollowingShijie Sun @TrAz5r
34 Followers 455 FollowingSanGe.AI @sange_ouyang
26 Followers 297 Followingfirecity @firecity8
0 Followers 478 Following摸鱼研究员 @wyatsky
21 Followers 215 Following凡姐此好 @YIFAN639231
8K Followers 173 Following 2015年进入币圈,接触第一个加密资产xrp,借助2017年大牛市东风,翻了几百倍,从此一直在这个领域投研、学习,也希望认识更多币圈正能量好友,一起成长!TempSir @TempVipGod
10 Followers 153 Following西沙旺老蘋果 @sushuwen218
745 Followers 4K Following 敬畏先贤 聆听智者In class society everyone lives as a member of a particular class, and every kind of thinking, without exception, is stamped with the brand of a class.nabm @vYUm5OAexZvrzOS
25 Followers 144 Followingmichael mok @michael33478855
106 Followers 262 Followingjackma @jackma88950145
153 Followers 5K Following๓єггץ @Hong17046563
89 Followers 2K Followingorange.ai @oran_ge
85K Followers 707 Following AI Researcher&Advisor |Think in public | Passionately Curious |Building Good Karmayihong0618 @yihong0618
63K Followers 3K Following 喜欢王小波,大概我们能成为朋友。 我的 2024 https://t.co/HfDF6oduB7 我的 2023 https://t.co/QyV8PiZmOY 我的2022 https://t.co/NLYTn7xtta 我的 2021 我的 2020乌鸦鸽鸽 @wuyagege
59K Followers 1K Following veritas vos liberabit 进度条:10% 书一页一页读,路一步一步走。 讲中文、英文、德文,学冷战史和欧洲史。 只为有耐心有慈心的中文读者写作。《不如读书》:https://t.co/l2GwKZWn3e瞎玩菌 @Blind___Gamer
72K Followers 419 Following 这世界破破烂烂,但总有人缝缝补补。 热爱分享自己的所见所闻所想,水印为出处。欢迎跟我讨论你的看法,不回复喷子。 游戏玩家/开发者/数字游民/奶爸。 我的游戏频道: https://t.co/DkquYAgWEo陈少举 (🦣 @ch.. @chenshaoju
60K Followers 1K Following 构成:30%生活,20%ACG,20%技术,15%查证,10%股市,5%政治。 PGP:https://t.co/tE5FodMBh0, Bitcoin:1DvdCDjUJ4bnqDgyzTAQ2xabw6ChRnQ9Sy, BitMsg:BM-GuKfKkQoZEX7Cmmg5ifTwnyhdihc9DnR。immusoul @ayuan1000
30K Followers 204 Following Work for Sanlian Lifeweek Magazine, cover science, travel, environment and music. Moved to Thread: https://t.co/6GyVMKDFS4luolei @luoleiorg
45K Followers 1K Following 💻 Front-End Developer / 🎬 YouTuber https://t.co/7g47VdNMnN / 🏦 Investing and Learning 📝 Blog https://t.co/6ucNiJ2gyg / 👨🚀 More info at https://t.co/smbFyIb6Hc重光.IMAGE @luciusyin_image
48K Followers 4K Following A PHOTOGRAPHER WHO LOVES HUMAN https://t.co/0S9B28x5Fo 在哪里跌倒就在哪里睡着云风 @cloudwu
41K Followers 70 Following 程序员 主要用 C 和 Lua 做开发 好写 Blog 爱玩桌面游戏 爱折腾 最近坚持攀岩 水平很差 不到 5.11a 工作非常忙Taylor Swift @taylorswift13
95.3M Followers 0 Following All’s fair in love and poetry... New album THE TORTURED POETS DEPARTMENT. Out now 🤍I'm not a pie @i_am_not_a_pie
20 Followers 60 FollowingOberurseler @EastEyesOnWest
503 Followers 868 Following Vintage collector, aesthetics enjoyer, hotel hunterErman Akkus @Erman_Akkus
1K Followers 945 Following MD, medical #oncology, internal #medicine specialist, @AnkaraUni @UniOslo, familial&precision #cancer genetics 🧬 Sharing&discussing cancer scienceShuhari @NSShuhari
1K Followers 709 Following Dad and Husband • Swift and UIKit • Formula 1 • Fujifilm • Volvo S90 Recharge居然sir @juransir
12K Followers 687 Following 专注品牌&营销|跨境电商|数码 3C 硬件|前产品经理|Formerly at @smartisan @ankerofficial |国内第一批 vloger(已全网销户)|🏋️一周至少健身三次|🚴十代 TCR 车主|🚶有空就去徒步|✈️ 去年游历 19 座城市的旅行爱好者HCC-LIVE Conference @HCCLIVEConf
767 Followers 893 Following Highlighting the multidisciplinary approach to advancing Liver Cancer care. Directors: @AnjanaPillaiMD @docamitgs @riadsalemIR @julieheimbach @DrElkhoueiryDr. Nina Niu Sanford @NiuSanford
6K Followers 2K Following GI Radiation Oncologist | Boston, @Princeton, @harvardmed, now @UTSWNews in Dallas | buying in bulk | @AAAS IF/THEN | Tweets=own | FCOI: https://t.co/EjwMnJKbthPedro C Barata, MD MS.. @PBarataMD
1K Followers 164 Following GU Med Oncologist at University Hospitals Seidman Cancer Center. Clinical trialistTom Powles @tompowles1
11K Followers 58 Following Interested in Urology Cancers, biomarkers and drug development.Maxime Ronot @maximeronot
605 Followers 456 Following Diagnostic and interventional abdominal radiologistTingting Zhang @Chaosdyna
313 Followers 596 Following A patient advocate and weaver of tech-enabled clinical research network. ASCOBT2019 awardee for mobile deployed care in Asia. FCOI https://t.co/ANJVkaY0oPAntonio D'Alessio @A_DAlessioMD
869 Followers 718 Following Medical Oncologist and PhD student at Imperial College London. HCC, immuno-oncology. Curiosity-driven.佐拉 @zuola
105K Followers 3K Following 移居台湾的楚国人 https://t.co/0W6q7wWWUr 键盘侠,网络工程师,写作者,自由主义者,盖蒂签约摄影师, 独立纪录片《HIGH TECH,LOW LIFE》主角,imdb编号:nm5051179 。 一个有梦想的人,希望能成为有趣的人。 電話+886 920955544 电子邮件:[email protected]WildCat 野猫 🏔�.. @WildCat_zh
5K Followers 542 Following @WildCat_io 中文版。 个人项目: 本地优先的稍后阅读,与个人知识库应用 https://t.co/tvgSJgcwx1 Mac 上自动复制短信验证码(free for now) https://t.co/QJib2CsxaFraighne @newRaighne
238 Followers 173 FollowingHongcheng Zhu 祝鸿�.. @DrHongchengZhu
546 Followers 1K Following MD, PhD. Radiation oncologist at Fudan University Shanghai Cancer Center, China. ESMO YOC, ASCO Editorial, IASLC ART #esophagus #lung #radiation T/RT = my ownHwang @hwwaanng
15K Followers 3K Following 男. 独立开发 ☕️SleepyCoffee ► https://t.co/5VvaXmaxfG|🎵 Lofi. ► https://t.co/Qc7AGBZy3C| 🐘 @[email protected] | 💻 Product Design for AFFiNE https://t.co/iisO5W1Sb1Geek @geekbb
57K Followers 411 Following 🧠在家居士 | 🥦素食者 | 🏃🏻马拉松爱好者 | 💰省钱小能手 | 搭🪜技术资深学者 | 👨💻科技宅 | 🆕更新狂 | 🆅 六边型战五渣Anthony,Esq. @flyingsoulcut
75 Followers 123 Following husband, father, son. Blogger:https://t.co/kMWx9msy3s 已开通OpenASK:https://t.co/aHirfSE62E coffee: https://t.co/r3ev0WE9Lbnewns @newns5
393 Followers 650 Following 电脑修理工,professional computer repair person; C++三脚猫,C++ tripod cat. 摄影器材爱好的穷人。十四姨 @AuntSannaha
13K Followers 1K Following 城乡结合部,杀马特,new poor,中年油腻,低端人口,废青,文艺中年,报丧界IE,N个自信。女神妹妹岑的粉丝。大妈控,中年妇女重度爱好者,广场舞资深叫兽。TFBOYS推特后援会成员。岁月静好,三饱一倒。我收入确实很高……。要恰饭。读书越多越反动。青山遮不住,毕竟东流去。Blocked by @uponsnowAnna Saborowski @SaborowskiAnna
715 Followers 202 Following Clinician/Scientist with a passion for hepato-oncology and basic science. #LiverTwitterJeff Ryckman @jryckman3
4K Followers 3K Following Medical physicist➡️MD. Passionate about #RadOnc. Focus on QoL⚖️, LR-PFS 🎯, OS, constraints🙅♀️, standardization, & reproducibility. #RadOncCalc @RadOncReviewMiableem⛱️ @MiaBleem
85K Followers 1K Following 人生是部RPG,感谢各位NPC|没有任何干货输出的废话碎碎念|ins:Miableem|不是骂人博主,是赛博清道夫|私联请发送Email至[email protected]Grainne O'Kane @graokane
1K Followers 581 Following Medical Oncologist; clinical and translational researcher pancreatic and hepatobiliary cancers. Views are my own 🇮🇪🇨🇦Xin Wei Wang @XinWang77
577 Followers 322 Following Senior Investigator at the National Cancer Institute with a special interest in basic and translational cancer research. Tweets and opinions are my own.scholl.chen @chenlane
87 Followers 1K Following🔘App推荐:优雅的RSS新闻阅读器”Bulletin”,基于iOS设计指南构建,并增强了强大的AI功能,支持智能摘要、改进标题 、小组件 、稍后阅读、管理提要等功能,体验下来有点像Arc,对于我来说订阅价格偏高(支持iPhone/iPad/Apple Watch/Apple Vision Pro/Mac /Apple TV)
提供一个中译全文阅读的镜像:archive.li/s9ZOs
哈哈,用自己开发的Markdown排版工具发布了公众号文章,标题渲染还有瑕疵,但是整体已经不错啦。 有兴趣的朋友可以访问 md.yicode.tech 体验。
这样子的话,我必须推荐一下我自己开发的 Markdown 排版生成公众号文章工具 👉 wangchujiang.com/wxmp/ 特点:可以修改 CSS 样式,超级高度自定义样式😄
哈哈,用自己开发的Markdown排版工具发布了公众号文章,标题渲染还有瑕疵,但是整体已经不错啦。 有兴趣的朋友可以访问 md.yicode.tech 体验。
Ollama 搭配 Open WebUI 实现本地开源大语言模型使用及体验 youtu.be/kODImps58WQ?si… via @YouTube
过去的一年,你被 OpenAI、Claude 封了号,下载了 OpenCat、ChatX、BotGem、ChatBox 等第三方客户端; 用了 NextChat、Chatgpt-vercel、Lobe Chat 等网页客户端; 部署了 OpenCat Team、OpenAI Proxy、Azure2OpenAI 等 Proxy 服务; Edge、Poe、hugging chat、perplexity 也在你手机上舍不得删除。
过去的一年里你尝试了 6 个闭源大模型,17 个开源大模型,给 5 个 AI 服务分别付了 20 刀。 问了 40 次你好,你是谁?在你的问题里鲁迅一共暴打了 72 次周树人,树上的 10 只鸟被射下来 28 次,小红书冰丝内裤文案被写了 9 次。 画了 30 次一只可爱的猫在太空,写了 100 次快速排序。请再接再厉。
写了第二篇关于 #ollama 的文章,真是越用越喜欢。 litterhougelangley.club/blog/2024/04/2…深入浅出-ollama-易部署的本地大语言模型框架:精彩体/
Next steps (non-exhaustive list): -Biomarkers (soon!) -personalized trial: pembro+/-vaccine (classic.clinicaltrials.gov/ct2/show/NCT06…) -Additive trial: Pembro +/- HIF2 inh (ascopubs.org/doi/10.1200/JC…) -Neoadjuvant strategies (stay tuned!) Onwards and upwards!
11/ Huge thanks to all the investigators, my partner @tompowles1, to @Merck, and mostly to our patients/families, to whom we dedicate all our efforts! Balanced editorial by @MVossMD & @motzermd nejm.org/doi/full/10.10…
主流程交互优化,纠结了近两个月今天终于发布,可以睡个安稳觉了。 对我而言,「交互」不仅是成就了愉悦的产品体验,更是用户体验之旅的「路书」。 清晰的流程设计,简洁易懂的错误提示,会让产品变得容易上手、简单好用。(写了好多catch、switch... AmyMind.com 伴你思考的AI思维导图
AI对话和思维导图之间的自然交互,我想了几个星期,一直没有头绪。这是我做产品以来,遇到的最难的、思考最久的一个交互了。期待灵光乍现的那一刻💫
这个推文勾起了我很多回忆,当年我大四(2013)在上海实习的时候,那时候租的房子就是群租房,只不过我住的次卧并不是隔断的,客厅隔断出来的小房间同样也是一对情侣在住,后来某一天下班回家看到了贴在门上的群租房清理通知,当时也没在意,再后来某一天下班回家开门发现一片狼藉,客厅里污尘漫漫,全…
想讲讲我为什么会来日本。 故事要从2017年讲起,那年北京大兴的一个城中村着火,烧死了几个人。 于是,北京开始清理低端人口。 所谓“低端人口”,指的就是我们这种不富裕的外地人。 当时我住在天通苑的一个群租房里,60平左右的房间,分割成了4个卧室。 我租了其中一间,月租3500。…
@cloudwu 分享几个我在学而思写过的讲义。如果这方面需求很多,市场很大的话,我可以考虑写一本完整的教材 drive.google.com/drive/folders/…
The most important video I’ve made for early career academics starting to do peer review. Nobody teaches how to do a good peer review but you are suddenly invited to do a peer review. So how to be a good peer reviewer? Here is my advice- youtu.be/ftstYE9hbCI
Looking forward to this presentation! @AACR @MattGalsky we plan to open the adjuvant trial @fredhutch @spsutkaMD @uwurology @OncoAlert @HsiehLab @JessicaHawleyMD @yawnyame @VivekSubbiah @sonpavde @shilpaonc @Dr_Aggen @DrRosenbergMSK @rohitjainMD @BhardwajLab @DrJohnSfakianos
Late breaking research from @BhardwajLab, @MattGalsky and colleagues at #AACR2024: Atezolizumab plus neoantigen vaccination for #bladdercancer abstractsonline.com/pp8/#!/20272/p… Poster, April 8, 9-12:30 @IcahnMountSinai
#1/8 Multicenter P1/2 trial of a personalized neoantigen vaccine + anti-PD1 (pembro) in 2L #HCC presented at #AACR2024 & published in @NatureMedicine ➡️nature.com/articles/s4159… ORR 31%,⏫historical control of pembro monotherapy (~17%) Details below:
频繁出现Cloudflare人机验证,可以用这个Cloudflare官方插件解决, chromewebstore.google.com/detail/silk-pr… ,装了之后,perplexity 再也不会动不动跳出人机验证了。
FDA approvals Tumor-Agnostic drugs: dMMR Pembrolizumab 2017 Dostarlimab 2022 MSI-H Pembrolizumab 2017 TMB-High Pembrolizumab 2020 NTRK fusions Larotrectinib 2018 Entrectinib 2019 BRAF V600E Dabrafenib + Trametinib 2022 RET fusions Selpercatinib 2022 HER2 3+ T-derutxecan 2024