Yifan Wu | 吴一凡 @yifanwu0731
Neuroscience PhD student at VIB-KU Leuven 🇧🇪 | Sleep 😴 🪰 | Synaptic transmission & plasticity 🧠🔬 Louvain, Belgium Joined July 2020-
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🧠 Excited by synapse-level brain mapping? Join us at a world-class institute to build molecular tools based on our new #LICONN work — and push the frontier of #MolecularConnectomics. Let’s decode the brain, one synapse at a time! hhmi.wd1.myworkdayjobs.com/en-US/External…
".....it is worthwhile to keep our results in record for a general service to the field." Limited involvement of Ca2+/calmodulin-dependent kinase II α and β in mammalian sleep biorxiv.org/content/10.110…
Calcium Biosensing Visual Guide 🧵 Calcium is a divalent cation that plays an important role as a second messenger in the cytosol ([Ca2+]cyt) of plant cells, mediating a myriad of signalling responses throughout development and in response to different environmental stimuli.
Most neurons in the cortex remain silent, even during sensory stimulation and behavior. What are these silent neurons good for? This is known as the “dark matter problem” of the brain. We address this problem in our @NeuroCellPress study led by @omgauld doi.org/10.1016/j.neur…
Very happy to have my friend @yifanwu0731 from @flysleeplab visiting us for the next 10 days to do some ExM of the 🪰 🧠
Catch up with the boss , Jakob Sørensen
Very excited to share our new study on synapse function. We show the fundamental interplay between receptor movements, desensitization and transmitter release in tuning high frequency synapse responses. This study will make you rethink the brain!!! biorxiv.org/cgi/content/sh…
Next post: 1000 reasons why we’ve left academia
Next post: 1000 reasons why we’ve left academia
#GameChanger Best paper of the year!!!LICONN is definitely a revolutionary technique and will benefit not only the field of Connectomics but also many others in neuroscience for sure! Stay tuned!!! Congratulations to the best of the best scientist, Mojtaba and the team ☺️
#GameChanger Best paper of the year!!!LICONN is definitely a revolutionary technique and will benefit not only the field of Connectomics but also many others in neuroscience for sure! Stay tuned!!! Congratulations to the best of the best scientist, Mojtaba and the team ☺️
Dear colleagues – we have an opening for a postdoctoral associate in the lab to study the molecular machinery of synaptic transmission and mechanisms by which neuronal subtypes differentially control synaptic strength. If you know of someone interested, have them email me. Thanks
Excited to share our work with @mlphillips17 about 9-color calcium imaging under a GRIN miniscope! Functional imaging of nine distinct neuronal populations under a miniscope in freely behaving animals. biorxiv.org/content/10.110…
It is not fresh to know that γ-secretases process APP to generate Aβ. But what do they cut in microglia? Why do they cut so many proteins in the meantime? Our paper just published in @MolecularCell provides new insights on these topics. Check it out: cell.com/molecular-cell…
"Friends" stars Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc and David Schwimmer paid tribute to Matthew Perry: "We are all so utterly devastated by the loss of Matthew. We were more than just cast mates. We are a family. There is so much to say, but right now…
Amazing set of data about #cilia localization, connectome and properties in the human brain by Anton lab. 51% of neuronal primary cilia engage in synaptic contacts. Some hints that cilia may even form gap junction with neighboring cells😮😮😮doi.org/10.1016/j.neur…
Haven't seen a Nature paper on synaptic plasticity in a while! This paper from Ulli Bayer's group shows that CaMKII's role in LTP induction is not enzymatic/phosphorylation of substrates like the AMPARs but a "structural" interaction with the NMDARs. nature.com/articles/s4158…
Dogs are humanity's best friend—but how long has it been that way? 🐕 This Science study investigated ancient dog genomes, revealing a complicated genetic legacy that reflects a long, shared history with humans. Learn more on #InternationalDogDay: scim.ag/3RS
🚨✨🧠🐭📰🚨 Interested in how defined neural populations of the insular cortex encode both emotional valence and anxiety-related behaviors ? Check out our work answering this exact question !! nature.com/articles/s4146…
Listen!!!
I am sure this one will create some discussions. We demonstrated that VNC neurons were key contributors to the sleep promoting capacity of a widely used “dFB-specific” driver. This confirms our finding. cell.com/current-biolog…
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