Alexander Hynes @APHage_
Father of Five. (he/him). Bacteriophages are amazing. Associate Professor, McMaster University. farncombephage.org Hamilton, Ontario Joined July 2019-
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That's one impressive host range, and not even in the top 5 coolest things about this story.
Et de deux! @DNADoubleFelix presenting the spoils of his PhD - Warhammer, Phage-Planters, and DNA. Oh, and a Thesis, I suppose. A masterful defence, a wonderful external @jwmodell... and there goes the last of the lab's starting cohort. *sniff*.
Ladies, Gentlemen - I present to you the first PhD out of the Hynes Lab - congratulations Dr. Al-Anany!
I am thrilled to share our work on a novel prophage-encoded phage defence from @theMaxwellLab: Anti-phage defence through inhibition of virion assembly nature.com/articles/s4146…
Oh dear. it looks exactly like what I would scribble if I were asked to draw a JAK-STAT pathway in an exam today. Uncanny.
Oh dear. it looks exactly like what I would scribble if I were asked to draw a JAK-STAT pathway in an exam today. Uncanny.
Marathon world record holder Kelvin Kiptum, dead at 24: runningmagazine.ca/the-scene/mara…
Position #1: The research program would characterize the diversity and dynamics of viruses and their relationship with their host and the environment. The research would combine genomics, functional genomics and experimental approaches.
🏆 Karen Maxwell @UofT wins an Arthur B. McDonald Fellowship in recognition of world-leading contributions to bacteriophage research and its applications. ▶️ tinyurl.com/32xv3smx
The Hynes Lab Halloween! Even with a song and routine, we couldn't overthrough the reigning champion Li Lab in the costume contest, although we did claim victory in the Pumpkins!
I don’t get this whole “correlation is not causation” thing. Every time I see a correlation, it seems to be causative.
An amazing poster by @JoseTamina from the Hynes lab (@APHage_) on probiotics, prophages and how they might interact! For the full story go see poster #42 and ask about her amazing work on Lacticaseibacillus! @CSM2023_Halifax #CSM_SCM2023 #CSM2023
When my 4-y old packs his lunch, it's by taking the easiest path to meeting our criteria for 'lunch'. With no consideration for the food he actually wants to eat that next day. There's a lesson there...
Check out our newest paper, examining phage cocktail synergy, highlighting temperate phage activity. Synergistic Interactions among B. cepacia Complex-Targeting Phages Reveal a Novel Therapeutic Role for Lysogenization-Capable Phages Micro. Spectrum journals.asm.org/doi/10.1128/sp…
Some thoughts on the politics of higher education these days. Tl;dr: it's much harder than it used to be to get politicians to focus on institutions. That probably means institutions need to update their lobbying strategy and tactics higheredstrategy.com/the-political-…
You'll never guess what Mystery Marathon I ran sunday - the pic could be anywhere! Everything came together for a wonderful, enjoyable (it's not just masochism, I swear) race. I improved on my other marathon time by almost 17 min, somehow finishing 2nd in my age category. Weeeee!
Not mentioned here; her comprehensive was 3 days later. And she nailed it. What a week!
Today I became a phage clinician… 1st research use of #phagetherapy cocktail to treat an infection in Canada Thank you to! @BCMTailorLabs & @AustenLee_T @IPATH & @chngin_the_wrld & @DocSaimaAslam @esgnta @Dr_Lori_Burrows @PhageAustralia @PhageCanada @AMMICanada #ammicanphage
While it's lamentable, I understand why I receive CVs that include marital status. I do *not* understand why I receive some with the candidate's height/weight. I guess I have joked that I need someone to use my stock of XS gloves?
Final thoughts on the Budget. We have work to do.
Last year's @bayracerun 30 k was my first race ever. I had a blast and knew I'd be back. This year, the re-match - and I improved by over 11 min, earning a coveted < 2 h gold medal (1:56:43), while still having a blast. I know where I'll be this time next year...
Brian Coombes, PhD @BrianKCoombes
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419 Followers 339 Following Microbiology BSc • Genetics Research PhD in @MarthaClokie lab @Leicester_Phage• All things bacteriophage • Studying at the University of Leicester, UKCentreforPhageResearc.. @Leicester_Phage
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705 Followers 735 FollowingBartłomiej Grygorcew.. @b_grygorcewicz
873 Followers 670 Following #bacteriophages and #superbugs cells biology enthusiast | interested in #phages #antibiotics #AMR and #biofilms | @pumszczecinSteven De Soir @StevenDeSoir
566 Followers 417 Following Phage Researcher 🇧🇪👨🏻🔬 LabMCT & UCLouvain. Opinions are my own! Music, Arts & Sports enthusiast 🎸🎨 ⛹🏻♂️Ana Juarez @Anaphage
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802 Followers 650 Following PhD student @SorekLab @WeizmannScienceRevathyKrishnamurthi @Revathykri
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98 Followers 268 Following MSc. Medical Science Student at @McMasterU | @Bercik_Collins Lab | @FFDHRI | Advocate for those who need and deserve to be heard.Bay Race 30k @bayracerun
3K Followers 132 Following Oldest road race in North America first run in 1894. Next race date March 24, 2024Congratulations to my AWESOME trainees @veronicantran and Ikram Qaderi for each being awarded 3-year, highly competitive @NSERC_CRSNG PGS-D salary awards for their PhD studies of #Pseudomonas type IV pilus #T4P-specific #bacteriophages!! 🥳🙌🥂🎉⭐️⭐️@BBS_McMasterU @McMasterIIDR
Assessing #phage-host population dynamics by reintroducing virulent viruses. @EmmaAllenVercoe shows colony isolation removes virulent viruses from gut #bacteria. Reintroducing virulent #virome to bacteria has specific impacts on community & prophages cell.com/cell-host-micr…
Ok so we have Faber-Castell markers on muslin using excess solvents from today's TLC lab (acetone/iPr/EtOH/water). If you have better mobile phase suggestions for cotton we can try a full t-shirt soon
We are recruiting two PhD students (4y) and one Postdoc (2y) to work on bacteriophage defense systems and their relevance for phage therapy. Come join our teams in Delft and Utrecht in the Netherlands. brounslab.org/vacancies/
Now published: "Phage predation, disease severity, and pathogen genetic diversity in cholera patients" science.org/doi/10.1126/sc… Check out the @ScienceMagazine podcast to hear co-senior author Eric Nelson talk about the twists and turns of our study: science.org/content/podcas…
This preprint has been a long time in the making. It follows up on pioneering work from nearly 100 years ago. Let's call it the "cholera bacteriophage enquiry, part 2." (1/n)
What a GREAT news ! CONGRATS @landrychristian ! Well deserved !
2024 Gairdner Award recipients paved way for revolutions in cancer treatment, genomics, and global health theglobeandmail.com/canada/article…
Happy to highlight our newly posted paper biorxiv.org/content/10.110… We show that P. aeruginosa prophages encode a component of the type IV pilus. This protein, which is homologous to the bacterial FimU protein, can be incorporated into the type IV pilus.
@vdlorenzo_CNB Smart organizers print the name in both sides.
Shawn French and team are 3D printing their way to new antibacterial chemical matter of unusual mechanism. Here, a semi-synthetic natural product (probably) hits the allosteric site of DNA gyrase. sciencedirect.com/science/articl…
Thank you so much @APHage_ for being an exceptional mentor. I am sincerely appreciative of everything you've done to help me succeed♥️
Ladies, Gentlemen - I present to you the first PhD out of the Hynes Lab - congratulations Dr. Al-Anany!
My toxic trait is that when I say I want a 1:2 dilution I mean a 50/50 mix but when I say a 1:10 dilution I mean a 10/90 mix
@APHage_ Hey! Nobody gave me a war hammer when I got my Ph.D! I was robbed! But good luck to all involved.
She gets a WARHAMMER for completing that's so rad
Ladies, Gentlemen - I present to you the first PhD out of the Hynes Lab - congratulations Dr. Al-Anany!
More (lambda) phage popping their (E. coli) bacterial hosts, this time in a little itty bitty colony. It's kind of magical that we can watch this happen... Sorry about the compression artifacts this website introduces, the raw video is quite stunning!
Y'all, look at these little cuties go pop! Lytic fluorescent lambda #phage being produced, and then lysing their cells. The loop is of ~1.5hr. The dramatic pop is about 20 minutes long.
@APHage_ I did have to make a catapult for my chemometrics class that dealt with DOE. To be gifted a Trebuchet for my PhD completion mhhhhh
Y'all, look at these little cuties go pop! Lytic fluorescent lambda #phage being produced, and then lysing their cells. The loop is of ~1.5hr. The dramatic pop is about 20 minutes long.