Chappell Lab @ChappellLab
RNA synthetic biology lab, Rice University chappell-lab.org Joined December 2020-
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Chappell Lab retweeted
The Stadler and Chappell labs (@ChappellLab) are hiring a joint postdoc to join an NSF-funded project on isolating and engineering environmental plasmids for microbiome engineering applications! Email [email protected] and [email protected] to apply.
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Chappell Lab retweeted
Online now @ Cell is the yeast multicellular engineering paper from @DrFankangMeng - the fruits of his productive PhD. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - adhesion, juxtacrine signalling and more. cell.com/cell/fulltext/…
Chappell Lab retweeted
📢 ALERT ALERT 📢 #BTO's monthly newsletter has dropped! Check it out for the latest and greatest opportunities over here at #BTO! Visit the @DARPA webpage for more info: buff.ly/5piNgIf 🫡
Chappell Lab retweeted
Excited to share our latest work on unraveling the role of a key metabolic pathway in human gut microbiome assembly and health-relevant metabolites—powered by machine learning! Led by the talented Yiyi Liu sciencedirect.com/science/articl…
Chappell Lab retweeted
It seems there are no free-living organisms known to rely exclusively on one other organism for their survival. Until perhaps now. Check out our latest publication in @NatureMicrobiol to see how we designed an exclusive microbial reliance using GCE. rdcu.be/ekepI 1/2
It seems there are no free-living organisms known to rely exclusively on one other organism for their survival. Until perhaps now. Check out our latest publication in @NatureMicrobiol to see how we designed an exclusive microbial reliance using GCE. rdcu.be/ekepI 1/2
Nice research briefing article on our @NatureBiotech paper on recording gene transfer using ribozymes in collaboration with @lauren_stadler @JoffSilberg labs! nature.com/articles/s4158…
Chappell Lab retweeted
Happy Sunday to all! This morning, we are excited to share Chase’s work developing a simple, scalable method to assemble 100s-1000s of custom genes from oligo pools using standard lab tools! (Small 🧵 below)
Chappell Lab retweeted
Happy to announce the our paper describing a new tool for tracking horizontal gene transfer using a splicing ribozyme has been published in Nature Biotechnology! Thanks to everyone on the team for their hard work nature.com/articles/s4158…
Chappell Lab retweeted
Information storage across a microbial community using universal RNA barcoding go.nature.com/440gL5E
Chappell Lab retweeted
Fresh in @NatureBiotech! We developed a synthetic biology tool for tracking gene transfer in microbial communities and applied it to study plasmid hosts in a wastewater microbiome. Awesome collab with @ChappellLab & @JoffSilberg and incredible students. nature.com/articles/s4158…
Fresh in @NatureBiotech! We developed a synthetic biology tool for tracking gene transfer in microbial communities and applied it to study plasmid hosts in a wastewater microbiome. Awesome collab with @ChappellLab & @JoffSilberg and incredible students. nature.com/articles/s4158…
Check out our latest paper on using synthetic RNA memory to record gene transfer across real microbial consortia. An amazing collaborative project at Rice U between @ChappellLab, @JoffSilberg, and @lauren_stadler labs! nature.com/articles/s4158…
Chappell Lab retweeted
Joaquin Caro Astorga's SubtiToolKit paper is published today. This cloning toolkit for Bacillus and Geobacillus was years of effort and indepedent work by @JCaroAstorga1, first in my lab and then with @erika_alden_d at the Crick. It's been a journey! sciencedirect.com/science/articl…
Chappell Lab retweeted
Excited to share our work in @ScienceAdvances! TLISA is a plug-and-play cell-free protein biosensor system developed by @MeganAMcSweeney. We hope this technology is a stepping stone to expand protein detection at the point-of-care! science.org/doi/10.1126/sc…
Chappell Lab retweeted
Title: Engineering Plasmids with Synthetic Origins of Replication biorxiv.org/content/10.110… #biorxiv_synbio
Pre-print alert: Introducing SynORI: Synthetic origins of replication for customizable and controllable plasmids! Lots of cool applications like co-maintaining six orthogonal plasmids in E. coli for a week and copy-control biosensors! biorxiv.org/content/10.110…
Chappell Lab retweeted
We are excited to make #CRISPR accessible to high school education. 🧬 Go check out the article in @StanfordDaily to read about our frugal CRISPRkits. #democratizingscience #scienceaccessibility @bioe_stanford @Stanford_ChEMH @Stanford stanforddaily.com/2025/02/03/cri…
Chappell Lab retweeted
@PaulFreemont opens the UK-Japan engineering biology meeting in Osaka. He pioneers the cell free synthetic biology and is now showcasing a suite of applications
Chappell Lab retweeted
Happy to share our new paper in @NatureMicrobiol on mapping spatial relationships of the human gut microbiome. We identified distinct spatial hubs between gut bacteria that reflect sub-community assemblies at the micron-scale. Led by Miles Richardson & co nature.com/articles/s4156…
Chappell Lab retweeted
ROSALIND 3.0 is out in @nchembio ! Cell-free biosensors are revolutionizing point-of-care diagnostics, but we need greater sensitivity to detect harmful chemicals. Enter: Polymerase Strand Recycling (PSR) — a game-changer for signal amplification! 🌟 nature.com/articles/s4158…
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