Chen Zhao @ChenZhao2011

Stadtman Investigator; focusing on thoracic malignancies (NSCLC, TETs); All tweets / comments are my own. Joined April 2017

Tweets

416
Followers

316
Following

456
Likes

780

Miriam Merad, MD, PhD @MiriamMerad

5 months ago

I asked ChatGPT : "what happens to nations invest more in the military than in science", it replied: “the fall of great empires — from Rome to the Ottoman Empire — always involved prioritization of force over knowledge, conquest over curiosity.” science.org/content/articl…

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Stephen V Liu, MD @StephenVLiu

8 months ago

Phase III EXCLAIM-2 trial of 1L mobocertinib vs chemotherapy in #EGFR exon 20 NSCLC @JCO_ASCO. Negative trial: PFS 9.6m in both arms (HR 1.04). RR 32% with mobocertinib and 30% with chemo. Mobocertinib also had 20% G3+ diarrhea. PAPILLON remains standard. ascopubs.org/doi/10.1200/JC…

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Stephen V Liu, MD @StephenVLiu

9 months ago

CHRYSALIS-2 Cohort A: amivantamab + lazertinib in #EGFR NSCLC after osimertinib and chemotherapy @JTOonline (n=162). BICR RR 35%, CBR 58%, DOR 8.3m, PFS 4.5m, OS 14.8m, and CNS efficacy noted. AEs included rash in 81% (G3 10%), paronychia in 52%. jto.org/article/S1556-…

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Drew Moghanaki @DrewMoghanaki

12 months ago

Great slide presented tonight by @LudaBazhenovaMD reminding us that it's no longer sufficient to know what street the EGFR mutation lives on, but instead what address it lives on so we know which TKI to prescribe.

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Eugenio Contreras @eugecc

2 years ago

😱Autoreactive CD8 + T cells are NOT DEPLEATED in the thymus during negative selection, instead, they are evicted from the thymus, where mechanism of peripheral tolerance controls their activation. science.org/doi/full/10.11… @ScienceMagazine @NIH

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Peter Westcott @PeterMKWestcott

2 years ago

Out today, with @LabJacks, @isidrolauscher, @fran_muyas, we used new mouse models of spontaneous lung and colon cancer to delineate a mechanism for why many patients with DNA mismatch repair deficient (MMRd) tumors may not respond to immunotherapy 🧵1/11 nature.com/articles/s4158…

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Patrick Forde @FordePatrick

2 years ago

#mars2 now online - surgery for mesothelioma 👀 big rethink on the way? #mesothelioma #WCLC2023

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Chen Zhao @ChenZhao2011

2 years ago

Very excited to start my group at NCI as a Stadtman Investigator! We are hiring postdocs with interests in #TumorImmunology #ComputerVision #lungcancer ccr.cancer.gov/careers/postdo… ccr.cancer.gov/careers/postdo…

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Chen Zhao @ChenZhao2011

3 years ago

Dear two-photon imagers: how do you keep your lens clean during long-term imaging (6-8hrs)? We use an inverted lens with a water pump and must clean it almost every hour...

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Stephen V Liu, MD @StephenVLiu

3 years ago

Overall, CheckMate 722 is another negative study but the subsets and landmark PFS rates suggest some patients may benefit. We are not currently able to identify them so we need better biomarkers or better combinations in this space. #ESMOAsia22

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Chen Zhao @ChenZhao2011

3 years ago

This study should be published in Science!

Rebecca Stevick @rjstevick

3 years ago

This study should be published in Science!

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Vinay Prasad MD MPH @VPrasadMDMPH

3 years ago

NEJM paper now out FIRST EVER RCT of colonoscopy With 10 year follow up, 42% adherence, no gain in colon cancer death nor all cause death I break down the trial, history & interpretation in 30 mins youtube video worth your time Here is an excerpt youtu.be/SMRS4-ng8T0

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National Cancer Institute @theNCI

3 years ago

Bacteria inside lung tumors concentrate within cancer cells, according to new research. The findings suggest that reducing bacteria in the lungs might benefit people with #LungCancer. ccr.cancer.gov/news/article/b… @nciresearchctr

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Ajit Johnson Nirmal @ajitjohnson_n

3 years ago

Multiplex imaging of a lymph node #spatialbiology. Mapping UMAP embedding and XY location of the extracted single-cell data! I'm making the script that I wrote to generate this animation available within scimap (see 👇). Would love to see what you create! scimap.xyz/tutorials/6_an…