Compound @CompoundVC
Compound is a thesis-driven, research-centric investment firm leading seed rounds :: :: What we're currently reading @compoundarxiv | Not called Compound VC compound.vc NYC Joined June 2009-
Tweets1K
-
Followers11K
-
Following153
-
Likes2K
Our team at @CompoundVC gathered clinical, partnerships, and financial data on 90+ most successful platform biotechs ever to more precisely understand what these companies typically look like as they scale Here's initial results (tho pls treat as illustrative, not as fact)
Read with full footnotes here: michaeldempsey.me/blog/2025/09/2…
(New essay) Narrative Cycle Entry A core reality for founders is that narrative timing has become a first-order strategic decision that demands the same rigor as product, GTM, or research. When announcing their company, founders should be aware of the point in the narrative…
🤫 Behind the scenes of our product showcase this week in Tokyo. With @NissanMotor we unveiled next-generation ProPILOT, integrated with @wayve_ai. ➡️ Over the last 2 weeks the Wayve AI Driver has been busy and has completed 52 demo drives with media in busy downtown Tokyo. 🇯🇵…
not going to write a blog post with lots of charts on this but tldr is i think the bears are wrong to me their best argument is that the fed is behind the curve, the economy is cooling considerably and the market is expecting a ton of cuts ahead of this (i.e. the market believes…
Delpho is... - a next-generation CDP purpose-built for Hyperliquid & designed to combine with our fully onchain yield-bearing stablecoin - able to offer the best borrow rates (0% or close) on Hyperliquid/HyperEVM - built from the ground-up, zero forks - a representation of what…
The examples below (not an exhaustive list) cover the four main archetypes of originators, focused on: - Speed and conviction - Research and expertise - Process and scale - Community and talent Each plays a vital role in ensuring that the top of venture capital's funnel is as…
New article - A Day in the Life of the World’s Most AI Forward Company How do we use agents at The General Intelligence Company? - We're always adding more context to the agent - We're running automations daily and overnight - We use Devin and Cursor for code gen More 👇
Over the past few years we’ve noticed both an intense desire to solve the various biosecurity problems in many ways, and also a feeling of uncertainty about how to take action both on the non-profit and for-profit side. We’re excited to bring everyone together to share research…
Over the past few years we’ve noticed both an intense desire to solve the various biosecurity problems in many ways, and also a feeling of uncertainty about how to take action both on the non-profit and for-profit side. We’re excited to bring everyone together to share research…
- Request 8–1,000+ GPU clusters - Get quotes from 50+ providers within 24 hours - Re-sell idle GPUs back to our liquid compute market, minimizing your costs - Dedicated support from our research team
- Request 8–1,000+ GPU clusters - Get quotes from 50+ providers within 24 hours - Re-sell idle GPUs back to our liquid compute market, minimizing your costs - Dedicated support from our research team https://t.co/aeC8uGADsJ
In a world of increasing scientific legibility, the resurrection of diseases like Measles, and the potential for man-made outbreaks, something must be done. At @CompoundVC , we've been obsessed with biosecurity for years. We've written extensively about how pathogens can be…
There’s a lot more perspectives in biotech than those we normally hear. Humbled to speak with the bio-art community tonight! @thisischristina @hdeweyh @BioBAT_NYC
Bring their most visionary biotech idea, we said People did…. > Ozempic for social media dopamine > Increase genetic variety through animal engineering > Human cryobanking > On-demand muscle modulation (fast/slow twitch) > Time controlled therapies from phages >…
Has been amazing using Cofounder by @nycintelligence and seeing the product come to life over the past few months. We are heavy users @CompoundVC across research, operations, and more. Excited for everyone to try it!
Has been amazing using Cofounder by @nycintelligence and seeing the product come to life over the past few months. We are heavy users @CompoundVC across research, operations, and more. Excited for everyone to try it!
Everyone needs a cofounder. That’s why we built the first ai agent that runs your business with you, remembers things, and knows everything about your business. Cofounder by @nycintelligence can automate, remember, and take actions on your behalf.
Big news at @PluralEnergy : we’ve raised a $7.13M seed round led by @paradigm, with support from @VoltCapital, @Maven11Capital, & @NeoclassicCap . Learn more in Axios: axios.com/pro/fintech-de… The time to upgrade electron economy financial rails is now🧵
@CompoundVC is hosting an Idea Factory event with @BenjaminAryaMD and Amulya in Boston next week. Link below to join!
@CompoundVC led our pre-seed and have been critical partners for the last two years. From the very beginning, @mhdempsey and @0xsmac believed in our vision and helped lay the foundation that brought us here.
(NEW POST) From Backrooms to Builder Codes > the shift from opaque off-chain venues to transparent onchain ones isn't just ideological > can tokens learn from the traditional equity lifecycle? > the hidden soft taxes of CEXs link to full piece below (co-written with @0xkrane)

Michael Dempsey @mhdempsey
29K Followers 5K Following Dreaming about the future, romanticizing the past | MP @compoundvc investing & researching former science projects & crypto | we are only creativity constrained
Nicole DeTommaso 🪄 @nic_detommaso
75K Followers 564 Following Tweet about All Things VC. Providing insights to demystify the industry🪄. Investor @HarlemCapital | @Columbia alum
nicole ruiz @nwilliams030
25K Followers 4K Following ☧ ambitious homemaker, wife to @rsanti97 // formerly: VC @compoundvc investing in former science projects ; core @ConstitutionDAO
Nathan Benaich @nathanbenaich
62K Followers 34K Following solo member of superinvestment staff @airstreet @airstreetpress @stateofaireport @raais
nihal @nihalmehta
28K Followers 2K Following @eniacvc @pitchandrunnyc @humanunicornpod. blessed dad 👦🏽👨🏽🐶. proud husband @reshmasaujani. jodhpur jain born in iowa 🇮🇳🇺🇸
🇮🇱🇺🇦🇹�... @alt1na1
5K Followers 7K Following tweets r mine not anybody else. rt/likes ≠ endorse #beef #freedom #ocean #defense #feral #Jesus #USA #GodBlessAmerica #workhardbekind pronouns: alpha/male/VITAL
Mac The VC @MacConwell
99K Followers 40K Following Managing Partner @RareBreedVC | underrepresented founders | Hacker turned Hustler | Entrepreneur | Vampire | Former Gamer | @inside | @KauffmanFellows class #26
Mike MacCombie 💬 @MikeMacCombie
13K Followers 6K Following Build something worth remembering, and meet people that light you up. Pre-seed VC. Curating best gems/opportunities in tech/VC: https://t.co/kl2jUnK97G
Andrew Gluck | Early-... @irrvrntVC
9K Followers 9K Following Early Stage investor: AdTech + Ecomm Enablement. CMO @ Twillory CMO + CoFounder @ huug
shann @shanvasion
6K Followers 3K Following small is beautiful. decentralizing tech @vana @livepeer forever hacker @ethglobal | prev @wef @MaRSDD @privycouncilCA
Nick Kōanni 光案�... @s11_lion
183 Followers 844 Following Co-Founder @insight_xyz Member @KumekaTeam silent koan breathes - answers ripple through the chain - Kōanni walks on
Testbed @EiriHQ
0 Followers 303 Following
Anil Peri @notanilp
46 Followers 300 Following building https://t.co/2JAa5hqE5b 🍚 backed by @techstars. prev. swiftskill (esports analytics; 1mn+ users). i love reading, building, and running
6star @0xasterism
129 Followers 321 Following
Jae @nickbae91
419 Followers 2K Following
Patrick Beatty @PatrickBea28286
0 Followers 40 Following Space tech investor at Beyond Earth Tech; mathematician, data science, tech, space, bioengineering, soccer playing and occasionally owning: The Town FC, Venezia
Super Debate @SuperDebateClub
74 Followers 309 Following Join us in reviving the art of debate. Participate in competitive, community-driven debate events or start your own chapter.
Hash Cash @Hashishcashish
159 Followers 443 Following Hash House Pre Launch - Discord link is bio is now open!
Enki Badamkhand @enkienkisf
7 Followers 58 Following
Cuan Chai @hicuanchai
41 Followers 1K Following 🇯🇲 Founder. AI aficionado. Always grateful. Repost ≠ Endorsement.
Noam Tenne @NoamTenne
60 Followers 169 Following Building Sky Valley Ambient Computing - https://t.co/EAXSqeq0SW | DTF - https://t.co/bHfs72mPtw
Anbalagan @anbu
17K Followers 12K Following Trader & Market Theorist. Pioneered Visual Trading (VT). Master of price ,time and astrology in markets 📉 📈 🪙 ♃ ☸️ 🧜♂️🔥🐅 🦅🇹 🐘🔱🐦⬛ 🔯 ♎
柚柚 $M | 🐜 @youyou8178
72K Followers 24K Following ❤️中英文KOL经理|#Binance 广场优质创作者 | ❤️ @JoinSapien 大使 ❤️#Binance 一键注册:https://t.co/CoFKV4C3j1 📩宣发私信我💌 TG: https://t.co/fzPJev7Uor
Brandon Neal @nycbrandonn
2K Followers 2K Following COO @eulerfinance; @BrettonWoodsCom member; Board @ahrvonetwork; Investor; @NewYorkFed Treasury Desk alum. Into kindness, macroecon, DeFi, & DER⚡🇺🇸🇺🇦🇹🇼🗽
Anon T @AnonT2025
54 Followers 266 Following Husband. Dad. Professor. Investor. Ex-entrepreneur. PhD in Management/IB. Crypto anon.
Nina Liu @Ninaliuser
32 Followers 159 Following co-founder & CEO of https://t.co/MRld8bTcG3, the AI short form video editing engine for consumer brands (coming soon) founder of Kite Beauty & Accenture Gen AI Innovation lead
Arif.mp4 @Arif_mp4
800 Followers 1K Following ex-@Ripple 🌑 | prev: CEO office // led Market Intelligence | working on internet money & ai
月亮 @yueliang52111
50K Followers 18K Following 早期项目挖掘丨项目推广丨抽奖福利丨 已入驻币安广场丨链游玩家 丨 信息整理 丨数据分析丨 #项目宣发丨 #合作私信 WEEX注册:https://t.co/FNNJHkjD1a TG:@yueliang5211314
RockyParadox @RockyParadox44
128 Followers 7K Following
Adryenn Ashley @adryenn
78K Followers 24K Following Founder/Managing Partner @slayventuresio #datascientist #VC #web3 #tvhost #slaysaturday
Edweird @SciencEddman
675 Followers 680 Following RNA enzymologist with a penchant for structural biochemistry and all things radio frequency.
petroo 🐧 @petroo__mm
40 Followers 579 Following Személyes blog YouTuber Befektető Gyűjtő Dubai - Budapest https://t.co/xiuRvgtuWn
Nitya (she/her) @oknitya
198 Followers 1K Following I sequence cells and study their RNA. @UAlberta & @lougheedcollege '21. Currently in Montréal! My views are yours. 🇨🇦🏳️🌈
Nootka @NootkaNika
72 Followers 203 Following Truth Seeker, Freedom Enjoyer. Building a metamorphic OSS @openthalis
G.M.Mc @G_M_Mc
0 Followers 901 Following
Möbius.Æ @200TUSD
295 Followers 6K Following
Grimothee Chalasorbet @americaforevs
617 Followers 918 Following My crypto-obsessed alt. Not financial advice.
vishwa @k_vishwa24
26 Followers 1K Following Integral Civilization - Funding Humanity Forward since 2025
Chongkal @Chongkal1
627 Followers 1K Following Co-founder at Tely AI – Get your company discovered in ChatGPT
Balikisu @Balkiss247
300 Followers 4K Following
Malika 🧬 @malikules
2K Followers 884 Following my job is about turning scientists into superstars (marble | inflection) 🌍 senior associate @ jabroni capital
Justin Hafner @j_haf_
41 Followers 121 Following DeepTech Venture Builder, Scientific Explorer, & Kinesiologist
Abtin Riasatian @ARiasatian
2 Followers 1K Following
Sina Zade @eblisiyun
2K Followers 1K Following You are either fertile, or you dont matter, Industrialist💡☁️ Building the worlds most sophisticated AI negotiator👔 לית אתר פנוי מיניה
Duane Moore @Duane1024
383 Followers 1K Following I'm in the empire business. Co-Founder/CEO @AtlasCDT 🏡
Perry Demsko @nandgatesonly
239 Followers 329 Following UPenn PhD, Full stack protein engineer. Making a completely human gene therapy vector at EndoFold. Opinions expressed here are mine alone.
ada🔸 @Adellama_
821 Followers 2K Following love, sadness and scientific-industrial capacity /// @evilada17875
sanyi.eth @sanyi_eth_
250K Followers 6K Following allin @HyperliquidX 努力做一个alpha博主,所有的推文都不构成投资建议 带🍚的推文是恰饭,不带的是正常的推文 #版本弃子 #链上电子乞丐 #话痨 wait for the wind collab➡️https://t.co/O5qim99qSG
Rational Exponentiali... @Rational_Expo
431 Followers 4K Following Rational Exponentialism 🧐📈 || #Tech #Stocks #News #Wisdom || *Neither financial advice nor endorsements*
C Bassett @Investorcb
17 Followers 135 Following
Michael Dempsey @mhdempsey
29K Followers 5K Following Dreaming about the future, romanticizing the past | MP @compoundvc investing & researching former science projects & crypto | we are only creativity constrained
Orbital @OrbMaterials
704 Followers 15 Following We use AI to design new materials, then put these into products for advanced industries, starting with data centers.
HairDAO 💈 @HairDAO_
7K Followers 680 Following 6 patents. 1 decentralized trial. Only at https://t.co/Vayx31Kgh5💈 Chat with our community at https://t.co/kOLr7ItYTQ
Abhishyant Khare @KhareAbhishyant
521 Followers 661 Following Cofounder / CTO at The General Intelligence Company of New York
andrew pignanelli @ndrewpignanelli
5K Followers 900 Following ceo @nycintelligence, i am going to get ai to run companies. “sweater boy” timeline to agi is 12 months
Manifest Finance @ManifestFinance
2K Followers 145 Following The best of U.S. assets in your portfolio. 🦅 Are you betting on America?
Val | Manifest (🇺�... @val_usa_crypto
718 Followers 324 Following bet on america. bringing crypto back to the US, contrarian views, devil's advocacy, and what i really think + @ManifestFinance
Mark Neumann @MarkNeumannnn
3K Followers 2K Following Head of ML at Orbital Materials. BC: Research/Eng at @allenai_org
Steve Martocci @smart
8K Followers 2K Following Co-Founder @joinSuppCo, @Splice, @GroupMe, @FlyBlade, and at it again this time as a new dad. Mostly Harmless.
Julian @JulianMoncadaNY
3K Followers 3K Following Co-Founder CEO @makegamesfast, investing https://t.co/8MZuFAujSb // advisor @joinbonsai @cryptTV prev: @lererhippeau @opentrons @treasure_DAO
Vincent Weisser @vincentweisser
24K Followers 4K Following @primeintellect ceo / open superintelligence & infra / automating ai & science
Turbo @makegamesfast
1K Followers 713 Following Next-gen 2D game engine built for making games fast 🎮🚀 https://t.co/Orp1ibvYn9
Prime Intellect @PrimeIntellect
48K Followers 28 Following find compute. train models. contribute to open superintelligence. https://t.co/ZRZOsRRbwr
Mackenzie Morehead @mackenziejem
2K Followers 1K Following Trying to figure out why the world goes round || Researching the edge @CompoundVC ||
Andrea Mata @esandreamata
2K Followers 615 Following Creative at @runwayml ✦ spanglish safe zone ✦ Mentor at @ADPList
Soleio @soleio
37K Followers 10K Following Designer, inventor, angel investor. Finding the element that secretly governs the whole. https://t.co/WN7QJAxCRu
PartyDAO @prtyDAO
32K Followers 23 Following Making crypto multiplayer. One app to create a group, gather funds, and coordinate on-chain.
Lindsey Winder (🏄�... @goforlindsey
3K Followers 1K Following Cofounder @hedgeyfinance Building token management for teams and their stakeholders. 4x founder
Magrathea @magratheametals
1K Followers 14 Following Metal without mining for the era of electrification and decarbonization.
Vega Shah @dr_alphalyrae
19K Followers 4K Following AI for Life Sciences & Healthcare @NVIDIA | trained as a scientist from @JGI, @UW, @UCBerkeley | building global community @TechBi0 | views are all mine
Offchain Labs @OffchainLabs
84K Followers 67 Following Advancing blockchain through @arbitrum, @prylabs, and @zerodev_app. Backing the next wave of innovation with Tandem Partner Studio & VC arm.
Steven Goldfeder @sgoldfed
37K Followers 928 Following Co-founder @OffchainLabs contributing to @arbitrum. Postdoc @cornell_tech/@initc3org. PhD @PrincetonCS.
smac @0xsmac
14K Followers 1K Following partner @compoundvc | your favorite alts favorite alt | host @smactalkpod | Mark 8:36 | normal is an illusion what is normal for the spider is chaos for the fly
Tyler Golato @GolatoTyler
11K Followers 995 Following science as play @triplicate_xyz. prev co-founder @molecule_dao @vita_dao @bioprotocol. molecular gerontology @NIHAging
Hedgey 🦔 @hedgeyfinance
7K Followers 454 Following Hedgey helps teams create & manage employee token vesting, investor lockups & community token claims. Trusted by @arbitrum @wormhole @ens_dao @Gaianet_AI + 200
Molecule @Molecule_dao
31K Followers 2K Following DeSci biopharma IP tokenization protocol. Fund & shape early-stage research ideas on https://t.co/wLCqaJVkVq & https://t.co/7oSlMRrzV8
Paul Kohlhaas bio/acc @paulkhls
25K Followers 4K Following dreaming of a scientific singularity / founder & ceo @bioprotocol @molecule_dao pioneering DeSci @vita_dao/ alum @Consensys @AfrikaBurn
Dr. Shelby @shelbynewsad
5K Followers 4K Following bio generalist, future maximalist. partner @compoundVC | writing https://t.co/5sTPXkvBCj
Sarcophagus ⚰️ @sarcophagusio
6K Followers 646 Following A decentralized dead man's switch on Base + Arweave. Release files when you want, to any ETH address, or the public: https://t.co/dxtjB44yZD
Defined @definedfi
13K Followers 980 Following The fastest and safest multi-chain trading terminal. Telegram: https://t.co/Y5UCi5JVhZ
Agoric @agoric
82K Followers 914 Following The blockchain product company building seamless, intelligent cross-chain applications—powered by Orchestration. Composers of @ymaxapp!
Robert Leshner @rleshner
132K Followers 2K Following CEO @superstateinc🗽 Investor at @robotventures 🤖, prev founded Compound; tweets / opinions / views are usually satire
Keep #tBTC @keep_project
31K Followers 447 Following Keep is building infrastructure for autonomous private data on public blockchains, DApps, & DAOs, including #tBTC. join us! https://t.co/mDBd4n2zUf
Compound Researcher @Compoundarxiv
2K Followers 19 Following What we're researching @compoundvc | DM @mhdempsey @shelbynewsad @0xsmac @mackenziejem to discuss
Brandon Ramirez @RezBrandon
4K Followers 3K Following Cofounder @graphprotocol & @edgeandnode. Building the fully decentralized web3 stack, leveraging tech, systems thinking and incentive design.
BionautLabs @BionautL
253 Followers 54 Following Revolutionizing the treatment of central nervous system disorders.
Yaniv Tal @yanivgraph
21K Followers 1K Following Founder & CEO @geobrowser. Cofounder @graphprotocol @edgeandnode @thehouseofweb3. Building a vibrant decentralized future.
The Graph @graphprotocol
343K Followers 2K Following The Graph is a web3 protocol for organizing and accessing blockchain data 🧑🚀 Official account of The Graph ecosystem 🌐
Edge & Node @edgeandnode
12K Followers 112 Following ⚡ Pioneering data infra for the next internet. Founding team @graphprotocol and 🏡 @thehouseofweb3. Powering web3, AI, and enterprise.
Tegan.eth @theklineventure
21K Followers 2K Following CoFounder & BoD @EdgeandNode, Launched @GraphProtocol | Ex @Barclays & BAML | @Forbesunder30 | Punk 2182 | @theinformation’s Top 10 | Censorship Resistance Maxi
Nick Neuman @Nneuman
12K Followers 1K Following I write about self-custody, cybersecurity, and building a #Bitcoin company | CEO & Cofounder of Casa @CasaHODL, the safest way to store your bitcoin