Daniel Fazakerley @DPhaz
Group leader at @IMS_MRL researching insulin action and glucose transporter traffic. mrl.ims.cam.ac.uk/research/princ… Cambridge, England Joined August 2009-
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Thank you to @DanielKlimmeck and especially to @NathalieMazure for this great News & Views related to our recent article. It certainly adds the discussion about oxygen availablity in cell culture
Thank you to @DanielKlimmeck and especially to @NathalieMazure for this great News & Views related to our recent article. It certainly adds the discussion about oxygen availablity in cell culture
Thank you @NathalieMazure for the thoughtful commentary on our work, and for putting these findings into context alongside other preceding studies on oxygen in cell culture! 🧫 embopress.org/doi/full/10.10…
Ever wondered how to present your #metabolism #data best? A new #methods commentary series @embojournal gives advice! To start @JohannesMeiser and Christian Frezza @FrezzaLab present guidance on how to reliably present and interpret #metabolomics results: embopress.org/doi/full/10.10…
How much pericellular oxygen do cultured cells experience? For differentiated cells, greater oxygen consumption than diffusion through culture medium actually causes hypoxic conditions! @joycelyntsi Sam Virtue et al @DPhaz @TVPLab @Cambridge_Uni embopress.org/doi/full/10.10…
Join us for a fantastic computational collaborative #postdoc opportunity to discover combination targets for cancers of unmet clinical need! Applications are evaluated on a rolling basis!
Join us for a fantastic computational collaborative #postdoc opportunity to discover combination targets for cancers of unmet clinical need! Applications are evaluated on a rolling basis!
Wonderful to see this out - many thanks to everyone involved in this great team effort.
We are hiring a Research Assistant in Human Nutrition and Metabolism. Applications are open until April 14. For more information: jobs.cam.ac.uk/job/45837/ Please share with your networks @IMS_MRL @MRC_Epid
Come join us! Fully funded PhD scholarship to continue our work on understanding the health benefits of exercise on the liver within the paradigm of small extracellular vesicle crosstalk (birmingham.ac.uk/study/postgrad…)
Congratulations @joycelyntsi. We are very proud of you!
Congratulations @joycelyntsi. We are very proud of you!
Announcing the Darlene Solomon awardee for 2024: Joycelyn Tan! Thank you to everyone that could attend the ceremony and celebrate with us. Thank you to @Agilent for sponsoring this award! #FeMS+ #EmpowerWomen #TeamMassSpec
Thank you to all our audiences who have made the 2024 @DarwinLectures such a highlight of the winter. We look forward to welcoming you back for the 40th annual Darwin College Lecture Series in 2025, for an exploration of Codes! darwin.cam.ac.uk/news/a-revolut…
Just received formal final confirmation that our MRC Metabolic Diseases Unit has been fully funded for 2024 to 2029 having obtained maximum possible scores for past work and future plans. Thanks to all the staff of @IMS_MRL who made this happen.
Great opportunity to join an excellent new lab and PI. Highly recommend
2y research assistant position (master degree or equivalent) on international collaborative project with me and Christine Allen, Toronto, to test temperature-sensitive liposomes for muscle drug-targeting in mice🐀. Please help me spread the word 🙏 jobportal.ku.dk/videnskabelige…
Great opportunity for #senescence#aficionados in one of the best lab at @karolinskainst @SpaldingLab @ICSA_senescence ki.varbi.com/en/what:job/jo…
Fantastic work @JulianvanGerwen, and @davidjamesoz team. Congratulations
Fantastic work @JulianvanGerwen, and @davidjamesoz team. Congratulations
This is a great programme for those starting their independent PI careers. The faculty are really supportive, if I say so myself 😆! You’ll make lifelong friends and collaborators, sharing in the stresses and celebrating successes of the journey. Apply!!
This is a great programme for those starting their independent PI careers. The faculty are really supportive, if I say so myself 😆! You’ll make lifelong friends and collaborators, sharing in the stresses and celebrating successes of the journey. Apply!!
✅💡 very happy to have this paper finally out. Chris and I started working on this project in 2017…so great to get this across the line at last! nature.com/articles/s4158…
✅💡 very happy to have this paper finally out. Chris and I started working on this project in 2017…so great to get this across the line at last! nature.com/articles/s4158…
Last chance for a interesting postdoc in our lab working with @AstraZeneca eur03.safelinks.protection.outlook.com/?url=https%3A%…
Inst Metabolic Scienc.. @IMS_MRL
3K Followers 325 Following Institute of Metabolic Science-Metabolic Research Labs. Research into diabetes, obesity and related endocrine and metabolic disorders.stephen o'rahilly (it.. @StephenORahilly
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743 Followers 924 Following Dorothy Hodgkin Fellow @IMS_MRL •Investigating how pregnancies with obesity impact on offspring hypothalamus•Mum to 2 kids & menagerie of pets•she/herFrezzaLab @FrezzaLab
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42 Followers 96 FollowingWe're excited to see you all tomorrow at the UK Proteostasis Network's kick-off meeting! 🎊📷
CoQ10 is a very hydrophobic molecule with poor bioavailability. In this new study, led by @LauraSteenberge, we build on prior work to show that the much more soluble CoQ4 is sufficient to rescue diverse CoQ functions and can be targeted to mitochondria. doi.org/10.1016/j.jbc.…
Dr Clémence Blouet is our 2024 Jens Sandahl Christiansen Awardee in Basic Science. She will deliver her Award Lecture in Stockholm at #ECE2024. Read on to learn more: ese-hormones.org/media/k3abte01… ECE 2024 takes place on 11-14 May – register: ese-hormones.org/education-and-… @EsePresident
Oxygen shortage: Himalayan adventures in an incubator embopress.org/doi/full/10.10… Great News&Views by Nathalie Mazure @C3M_U1065 @Univ_CotedAzur on the recent Daniel Fazakerley @DPhaz et al embopress.org/doi/full/10.10… Merci, Nathalie for your sharing interesting historical data views!
Thank you @NathalieMazure for the thoughtful commentary on our work, and for putting these findings into context alongside other preceding studies on oxygen in cell culture! 🧫 embopress.org/doi/full/10.10…
Good things come in threes: 1) paper that we’re really proud of accepted 🧠 2) great visit and exciting project for new NIH OxCam PhD student 👩🏻🔬3) Spring is finally here in Cambridge☀️ Celebrating with over- priced doughnuts!!
“New paper out” Celebratory donuts with @ozannelab. Thank you @lauradearden3 🎉
Epic birthday meal with Jane @Beautifullight1 at @YauatchaCity
My functional validation of a causal variant at the FAIM2 obesity GWAS locus is out today in @CellGenomics! (1/4) cell.com/cell-genomics/…
in this case a dom. negative mutation in LXRa leads to much more severe hepatic damage and fibrosis than a total KO, all in the presence of little triglyceride in hepatocytes. Clin signific. supported by assoc of proven LoF mutations with markers of hepatic damage in humans
biorxiv.org/content/10.110… Some lovely work in humans/mice from @slockhart05 #milanmuso and lots of our collaborators. As we found with PPAR gamma ~ 25 years ago, studying the impact of dominant-negative mutations in nuc. receptors can lead to surprises
biorxiv.org/content/10.110… Some lovely work in humans/mice from @slockhart05 #milanmuso and lots of our collaborators. As we found with PPAR gamma ~ 25 years ago, studying the impact of dominant-negative mutations in nuc. receptors can lead to surprises
@DagmarWachten @Kornfeld_JanW @NatMetabolism @TRR_BATenergy Congratulations!
Presenting metabolomics analyses: what’s in a number? As part of a methods advice series, Meiser and Frezza highlight frequent pitfalls and offers guidance related to designing, processing, and communicating metabolomics analyses @JohannesMeiser @FrezzaLab embopress.org/doi/full/10.10…
@BDALizStockley @NutritionSoc @BDA_Dietitians @BDAPublicHealth Thank you 🙏 It was a fantastic session and great opportunity to put forward the case for workplaces as a key component to nutritional health of working age adults
Ever wondered how to present your #metabolism #data best? A new #methods commentary series @embojournal gives advice! To start @JohannesMeiser and Christian Frezza @FrezzaLab present guidance on how to reliably present and interpret #metabolomics results: embopress.org/doi/full/10.10…
Last talk of the morning at #METPHYS2024 we’re traveling into the mitochondria of AML with @KFW_Lab
Honoured, although the cat couldn’t care less, to have been awarded a prize for one of the top talks at #SGGD2024 A great meeting with some spectacular science
The first of my two papers from my PhD work in the @SempleLab at @EdinUniCVS is now out! Really enjoyed the opportunity to collaborate with @LoraHeisler and @pablomorentin on this project. sciencedirect.com/science/articl…
Congratulations to all… Angharad Evans’ first time representing GB will be stepping out at Paris Olympics #Harrithehammer
Announcing our 33-strong swimming and marathon swimming squad for @Paris2024 🏊 Welcome to Team GB. @Aquatics_GB | @EurostarUK
My 5 year old was just in time to get a red passport when she was a baby, but now it’s been renewed both kids have blue passports and I think it’s time to purchase a couple of these #bollockstobrexit
Perilipin membrane integration determines lipid droplet heterogeneity in differentiating adipocytes dlvr.it/T5Mtg4