The EMBO Journal @embojournal
Rapid publication of research in molecular, cell & organismal biology. Part of @EMBOPress. Tweets by editors. On Mastodon: @[email protected] emboj.embopress.org Joined December 2013-
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Presenting metabolomics analyses: what’s in a number? As part of a methods advice series, Meiser and Frezza highlight frequent pitfalls and offers guidance related to designing, processing, and communicating metabolomics analyses @JohannesMeiser @FrezzaLab embopress.org/doi/full/10.10…
How do type-I interferons & IFN𝛄 induce different immunological responses? Thomas Decker et al find similar initial transcriptional programs, which however diverge at later points due to differential engagement of ISGF3 and IRF1 transcription factors embopress.org/doi/full/10.10…
Krebs cycle succinate-CoA ligase SUCLG1 restricts POLRMT succinylation to enhance mitochondrial biogenesis and leukemia progression embopress.org/doi/full/10.10…
Just one week left to conference register for an emerging topic in Plant Biomechanics in Singapore! 🇸🇬We will explore interdisciplinary insights from single molecule, complex, to tissue level, blending advanced imaging, mechanical modeling, physiology, and plant pathology. 🍀🌲🌿
A nanobody toolkit for tracking or blocking nuclear pore complex (NPC) biogenesis identifies a checkpoint linking assembly of the NPC scaffold to formation of the Np98-dominated permeability barrier Dirk Görlich and coworkers @NPC_aficionado @mpi_nat embopress.org/doi/full/10.10…
Common regulators of dysfunctional “anergia” and “exhausted” natural killer cells can be targeted to restore cytotoxicity and anti-tumor activity Mira Barda-Saad and coworkers embopress.org/doi/full/10.10…
The EMBO Global Investigator Network supports group leaders setting up their laboratories in #Chile, #India, #Singapore or #Taiwan. Apply by 1 June: embo.org/funding/fellow… #lifesciences #funding
Non-vesicular phosphatidylinositol transfer plays critical roles in defining organelle lipid composition Tamas Balla @NIH and coworkers embopress.org/doi/full/10.10…
Transcriptional rewiring of an evolutionarily conserved circadian clock: Luis Larrondo @lflarrondo and collaborators show that basic circuit topology can be dramatically changed, while still yielding a functional semi-synthetic clock embopress.org/doi/full/10.10…
Apicomplexans that undergo binary division like Toxoplasma DO have G2 cell cycle phases; controlled by CDK/cyclin pair Crk4-Cyc4 & a new inhibitor of reduplication Lauren Hawkins, Elena Suvorova et al @USFHealthMed #RefereedPreprint c/o @ReviewCommons embopress.org/doi/full/10.10…
What is the essential role of METTL16-mediated RNA m6A modification in early embryonic development? IGF2BP1-mediated stabilization of mRNA for the MYBL2 transcription factor drives G1/S progression in hematopoietic stem and progenitor cells embopress.org/doi/full/10.10…
Cryo-EM of native γ-TuRC-capped microtubules from frog egg extracts shows transition from open to partly closed conformation, with local misalignments in the RanGTP-dependent nucleation pathway Elmar Schiebel, @PfefferCryoLab et al @ZmbhH @UniHeidelberg embopress.org/doi/full/10.10…
TEAD2 initiates ground-state pluripotency by mediating chromatin looping embopress.org/doi/full/10.10…
Identification of histone H3 chaperone DNAJC9 as a factor restricting CENP-A mislocalization reveals the importance of proper histone H3-H4 supply in ensuring CENP-A centromere targeting Munira Basrai @BasraiMunira, Colin Hammond @needfuzz and colleagues embopress.org/doi/full/10.10…
Transcription factor functional interplay: During B-cell activation, BACH2 restricts plasma cell differentiation by heterochromatin-mediated transcript inhibition & by preventing IRF4 homodimer accumulation Kyoko Ochiai, @kazuigarashi and colleagues embopress.org/doi/full/10.10…
TLDc-domain proteins Rtc5 and Oxr1 regulate assembly and subcellular localization of the yeast V-ATPase @AyelenGonzalezM and coworkers #RefereedPreprint c/o @ReviewCommons embopress.org/doi/full/10.10…
Out just now @embojournal: our cryo-EM structure of the native RanGTP-induced γ-TuRC-capped microtubule, revealing a surprisingly asymmetric minus end architecture with direct implications for microtubule regulation and modulation during spindle assembly. embopress.org/doi/full/10.10…
An AGO10:miR165/6 module regulates meristem activity and xylem development in the Arabidopsis root embopress.org/doi/full/10.10…
Molecular Cell @MolecularCell
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2K Followers 610 Following Our diverse lab at @TheCrick studies mechanisms of DNA repair at breaks/forks/telomeres in health & disease | Tweets by lab members unless signed SB | Views ownEver wondered how to present your #metabolism #data best? A new #methods commentary series @embojournal gives advice! To start @JohannesMeiser and Christian Frezza @FrezzaLab present guidance on how to reliably present and interpret #metabolomics results: embopress.org/doi/full/10.10…
This morning I had an accident resulting in a large soft-tissue hemorrhage. In the ER, I went suddenly into hypovolemic shock. The ER team reacted immediately by squeezing 500ml Ringer/ephedrine and saved my life. I am now in the ICU, heavily cabled but stable.
@MareikeAlbert @CRTDpress @embojournal Thank you so much for trusting me with this cover! Huge congratulations!
#WeekendRead! #EveryCellIsAnImmuneCell! Raghavan &co show @embojournal that in #skin epidermis ROS drives glycolysis & lactate! Lactate uptake by macrophages boosts their TCA cycle & matrix remodeling via MPP9 to drive #sterile #inflammation & #psoriasis! doi.org/10.1038/s44318…
A group of researchers screened factors essential for ESC #pluripotency. They identified TEAD2 as an ancillary factor maintaining ground-state pluripotency in 2i/LIF #ESCs and facilitating the transition from serum/LIF to 2i/LIF ESCs. @embojournal | 🔗 bit.ly/3xCJrDM
A huge congratulations 🙌 to @groth_anja, @ChoudharyLabCPR, and @duxin_lab on these fantastic and well-deserved achievements with @ERC_Research grants🏆🍾 #CPRlegacy
☀️ Exciting news! It's raining ERC grants at CPR @UCPH_CPR 🥳🍾! Huge congrats to Chuna Choudhary @ChoudharyLabCPR and Anja Groth @groth_anja for landing ERC Advanced Grants, and Julien Duxin @duxin_lab for securing an ERC Consolidator Grant. #ERCGrants
Out just now @embojournal: our cryo-EM structure of the native RanGTP-induced γ-TuRC-capped microtubule, revealing a surprisingly asymmetric minus end architecture with direct implications for microtubule regulation and modulation during spindle assembly. embopress.org/doi/full/10.10…
Beyond excited to share my first paper from my PhD @DPhaz Lab @IMS_MRL now out in @embojournal! Special thanks to Sam from @TVPLab and @dougall_norris for co-leading this project with me. We found that many cell culture models, despite living in 18% oxygen, are hypoxic! 🧵below:…
Delighted our paper on oxygen tension in cell culture is now out in @embojournal. Particular congratulations to @joycelyntsi (see her🧵here). Thank you to our many collaborators, and to funders @wellcometrust @The_MRC @TheBHF 👇 embopress.org/doi/full/10.10…
Beyond excited to share my first paper from my PhD @DPhaz Lab @IMS_MRL now out in @embojournal! Special thanks to Sam from @TVPLab and @dougall_norris for co-leading this project with me. We found that many cell culture models, despite living in 18% oxygen, are hypoxic! 🧵below:…
- Wait a minute, is this a "special issue"? - No, no, it's a "themed collection".
Our new paper about the structural mechanism by which RAD51 assembles at double-stranded DNA break sites on chromatin has been published in Nature! doi.org/10.1038/s41586… #CryoEM #Nucleosome #RAD51 #DNArepair
What a terrific decision by @EMBO to support life science researchers in India !!!
EMBO announces the launch of a pilot scheme to support Open Access #OA publication by life scientists performing their #research in #India. embo.org/features/suppo…
This is a landmark decision. Thank you @EMBOPress for this
EMBO announces the launch of a pilot scheme to support Open Access #OA publication by life scientists performing their #research in #India. embo.org/features/suppo…
OK, I've never seen this before, but I sent an email to someone and they REACTED to it. Like I literally got back an email reply that was just a "reaction". Not sure how I feel about this😅
@YehuMoran @emboreports @EMBOPress One of the best (and late) innovation @embojournal has begun. Really looking forward to all the papers you’ll be editing :)
Even research institutions can have a younger sibling! Together with @NOVAunl, we establish the NOVA Institute for Medical Systems Biology (NIMSB) based on the @BIMSB_MDC model. Read our interview with project leads @apombo1, @ajacinto, @stan_gorski: mdc-berlin.de/news/news/berl…
great news! hoping to be able to say 'welcome back, CH' soon. For the moment, the @ERC_Research welcomes your applications 🇨🇭 Switzerland!
📣 Good news! As negotiations between the 🇪🇺 EU and 🇨🇭 Switzerland have been officially launched today, researchers based in Switzerland can now once again apply for ERC grants. Read more 👉 erc.europa.eu/news-events/ne…
Spring has arrived at our rosy institute @institutrb 🌸
Hace poco me preguntaba un alumno cómo hacía la célula para evitar la reactivación de orígenes de replicación, la que conllevaría a la amplificación del DNA. Hoy el grupo de @JMendez_DNA @CNIOStopCancer publica en @embojournal la respuesta: RAD51-PRIMPOL-MRE11
A new study from our group @CNIOStopCancer is out today @embojournal. embopress.org/doi/full/10.10…. A short, 7-tweet summary follows (1/7).