Feltham Lab @FelthamLab
We smash & trash; we #PROTAC and attac 💣 We discover new drug targets & hijack the #ubiquitin system to remove them💊 Tweets by PI @BekkyFeltham @WEHI_research Melbourne, Victoria Joined November 2019-
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Feltham Lab retweeted
Heads up for those working in ubiquitin biology and targeted protein degradation—Lorne Ubiquitin 2025 is happening 20–23 November in Lorne, Victoria, Australia. Late abstracts are still being accepted—worth checking out!!! 🦘🦘🦘
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Feltham Lab retweeted
Had an exciting morning of #TargetedProteinDegradation at the launch of Ternarx! @ternarx49306 Fantastic to have strong support from @Mark_Butler_MP and the incredible team @WEHI_research. 🔗 Explore our journey and vision: [WEHI Announcement](wehi.edu.au/news/wehi-spin…)
Had an exciting morning of #TargetedProteinDegradation at the launch of Ternarx! @ternarx49306 Fantastic to have strong support from @Mark_Butler_MP and the incredible team @WEHI_research. 🔗 Explore our journey and vision: [WEHI Announcement](wehi.edu.au/news/wehi-spin…)
Excited to be part of the CeTPD scientific opening #TPDFocus @dundeeuni
🔬2024 Lab Update! 🌟 Farewell to incredible team members, @DanielSimpsonAU and Anna Gabrielyan. Wishing them success as postdocs!💙Excited for new faces and opportunities in 2024. Here's to innovation, collaboration and new discoveries🚀 #LabLife #NewBeginnings #Science2024
Unlocking the secrets of the E3 ligase MIB2!🕵🏻♂️ Our new paper @PNASNexus unravels the mysteries of MIB2 in mice with the cpd mutation, and its unexpected role in wound healing 🐁🩹 An excellent study we're thrilled to share!#wehiresearch #MIB2Discovery academic.oup.com/pnasnexus/arti…
Feltham Lab retweeted
Abstract submissions for 2024 @LorneProteins, incl. the Satellite Meeting on "Ubiquitin signalling: Molecular mechanisms, biology and targeted protein degradation" are closing soon. If you work on #ubiquitin, ubiquitin-like modifiers, #PROTACs or #TPD, we want to hear from you!
Great talk from @mediocre_jake today talking all things E3 ligase, a favourite topic in the @FelthamLab @WEHI_research
Well done Anna Gabrielyan for a fantastic talk for @AusCellDeathSoc @WEHI_research today. Great story and really interesting data 🤓😎
Feltham Lab retweeted
The Vervoort and @FelthamLab @BekkyFeltham are looking for an enthusiastic Research Assistant who wants to join our labs for a year to kickstart an exciting new project on degron therapeutics in cancer. Check it out and please share: wehi.wd3.myworkdayjobs.com/en-US/WEHI/job…
Feltham Lab retweeted
WEHI researcher Dr @BekkyFeltham was always intrigued by biochemistry. These days Dr Feltham heads up a #UbiquitinSignalling laboratory searching for new therapies to treat #InflammatoryDiseases Discover more in the new edition of Illuminate wehi.edu.au/news/illuminat…
@FelthamLab Christmas Shenanigans continued @CargoRestaurant with our end of year awards. The best mistake award this year going to @BekkyFeltham #MerryChristmas
@FelthamLab Christmas Shenanigans @archiebrothers, great afternoon of arcade game fun 😁 #festiveseason #MerryChristmas
Excellent #PhD confirmation seminar today by Philipp @WEHI_research well done!
Well done @TamerAly_Tam for an excellent PhD confirmation seminar today @WEHI_research #PhDconfirmed #phdlife
Feltham Lab retweeted
Paper free to read in @nchembio: rdcu.be/cYUib. doi.org/10.1038/s41589…
Feltham Lab retweeted
#cIAP1-based %degraders induce #degradation via branched #ubiquitin architectures | Nature Chemical Biology nature.com/articles/s4158…
Feltham Lab retweeted
An expanded Lexicon for the Ubiquitin code by @IDikic @IBC2_GU & Brenda Schulman @MPI_Biochem 😳 New types of #Ubiquitin modifications on serine, threonine, lipids, sugars, also on ADPR..opportunities for innovative #therapeutics nature.com/articles/s4158… rdcu.be/cYfBR
Feltham Lab retweeted
Wow!!! Congratulations @Nurix_Tx for having achieved a complete (!) response in a patient with aggressive Non-Hodgkin's Lymphoma using their using a small molecule degrader. So wonderful to see these clinical data emerge with targeted protein degradation! ir.nurixtx.com/news-releases/…
Feltham Lab retweeted
A big mystery solved? Endogenous function of the CRBN Ligase revealed by Christina Woo et al @Nature!! Spoiler…it’s all about protein quality control. CRBN recognizes damaged proteins with cyclic di-peptides that mimic IMiDs! So cool👏👏 nature.com/articles/s4158…
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