Peggy Goodell @Goodell_Lab
The Goodell Lab. Hematopoietic stem cells, epigenetics, DNA methylation. Chair, Dept of Mol Cell Biology at Baylor College of Medicine. Tweets my own. goodell-lab.com Houston, Texas Joined March 2012-
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Peggy Goodell retweeted
amazing findings of alternative functions of DNMT3A by @challenlab
amazing findings of alternative functions of DNMT3A by @challenlab
Peggy Goodell retweeted
We had the honor to preview @TheKingLab's new publication in @CellStemCell; 'Plot Twist: TET2 Clones Save the Brain'. If you are interested in peripheral vs. central immune cells in the brain in health and disease, check it out! sciencedirect.com/science/articl…
Peggy Goodell retweeted
Delighted to share our latest on longitudinal methylation dynamics preceding cancer. Epigenetic signs of AML appear in blood DECADES before Dx. By brilliant @__AFonseca ✅Early cancer ✅Methylation drivers ✅Epimutation rates ✅CpG lineage tracing biorxiv.org/content/10.110…
Peggy Goodell retweeted
Happy to share our recent review as part of the @CellStemCell Hallmarks series, co-authored with friends/colleagues/collaborators, Anne Brunet (@BrunetLab) and Peggy Goodell (@Goodell_Lab) Hallmarks of stem cell aging: Cell Stem Cell cell.com/cell-stem-cell…
So sad to hear of Atul Butte’s passing. @atulbutte. Fortunate to have briefly crossed paths. To know him for a millisecond was to immediately appreciate his generosity, brilliance, and warmth. He was always thinking, always inspiring. RIP
So thrilled to have you join the team!
So thrilled to have you join the team!
Peggy Goodell retweeted
Excited to share the @Goodell_Lab News&Views on 3 exciting studies by @VassiliouLab, Chan Lab, and @TrowbridgeLab in @Nature and @NatureComms, showing that blood stem cells with mutant #DNMT3A (major driver of Clonal Hematopoiesis) depend on enhanced mitochondrial respiration ⬇️
Time-resolved single-cell resolution of cancer development in patients. Deep insights into a leukemia (CML) that has taught the field so much. From an abnormal chromosome (Nowell and Hungerford 1960), to reciprocal translocation (Rowley 1973), to BCR-ABL (Baltimore, Witte,…
Time-resolved single-cell resolution of cancer development in patients. Deep insights into a leukemia (CML) that has taught the field so much. From an abnormal chromosome (Nowell and Hungerford 1960), to reciprocal translocation (Rowley 1973), to BCR-ABL (Baltimore, Witte,…
Thrilled to share our work on stem cells and #aging in the hematopoietic system! Lots to dig into, and some interesting parallels and distinctions from human #aging and clonal hematopoiesis.
Peggy Goodell retweeted
How blood ages - A curious case of mice and men. Our latest study @Nature published today. Biological processes such as DNA mutagenesis often scale to animal time. Blood stem cells have special evolutionary protection against this. 👉🏽nature.com/articles/s4158…
Peggy Goodell retweeted
Cool study on the cover of new @CD_AACR Cancer Prevalence across Vertebrates By @cmaley @amy_boddy Using >16,000 necropsy records across ~300 species, the authors show that neoplasia prevalence (& somewhat more modestly cancer) increases with adult body mass (contrary to Peto’s…
Was great day to run for the @ASH_hematology foundation run/walk with @TheKingLab @challenlab et al ! #ASH24!
Peggy Goodell retweeted
#ASH24 my poster ready. Hope it leads to CH prevention! Appreciate your fantastic mentorship @Goodell_Lab Would like to thank Dr. Benjamin Ebert and @biomiko for this importan collaboration, For research suport @LLSusa And don't miss @VenkatSundrmrty Goodell Lab talk on Monday!
Peggy Goodell retweeted
🎉 Thrilled to share the @RibackLab’s first PhD defense! Huge congrats to @Gandhar_Datar and co-advisor @Goodell_Lab ! 🎓🔬 Gandhar’s work in biophysics and leukemia led to the discovery of a new phase-separated condensate that drives leukemias. Stay tuned for more insights!
MCB department tradition! #Halloween party w pumpkin and costume contests. #newPI wins!
Peggy Goodell retweeted
Submit an abstract by November 18 for the AACR Special Conference on DNA Methylation, Clonal Hematopoiesis, and Cancer (February 1-4, San Diego), chaired by Stephen B. Baylin, Margaret A. Goodell, and Peter A. Jones. bit.ly/48miPFr #AACRmethylation25 @Goodell_Lab
Great to have Adam Wilkinson @awilkinsongroup visiting the @BCMCancerCenter today hosted by @TheKingLab . Fantastic talk about HSC expansion and exciting genetic in vitro and in vivo screens!
Peggy Goodell retweeted
1/A picture is worth a thousand words but what if they can say more?! We developed live-cell FLIM approaches to track protein interactions within RNA-protein condensates – Our first paper is now out in @JCellBiol! doi.org/10.1083/jcb.20…
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ASH @ASH_hematology
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