Gunning Group @GunningLabUofT
Multidisciplinary team of molecular architects using #medicinalchemistry & #molecularrecognition to design better medicines. 🧵 gunninggroup 🐘 gunninglabuoft gunninggroup.ca Mississauga, Ontario Joined December 2019-
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Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism" —the 1st human to undergo custom genome editing —outgrowth of decades of NIH funded research nejm.org/doi/full/10.10… nejm.org/doi/full/10.10… @NEJM…
NEW SITE LAUNCH! braincancercanada.ca NEW! Researchers & Scientists: braincancercanada.ca/researchers-an… NEW! Patient & Caregiver Resources braincancercanada.ca/patient-caregi… NEW! Projects Funded braincancercanada.ca/projects NEW! Community braincancercanada.ca/community #braincancer
In case you missed it: 'Microwave-assisted synthesis of pomalidomide building blocks for rapid PROTAC and molecular glue development' Fom Patrick Gunning and colleagues at @GunningLabUofT buff.ly/FMUUweh
Monoselective Histone Deacetylase 6 PROTAC Degrader Shows In Vivo Tractability | Journal of Medicinal Chemistry pubs.acs.org/doi/abs/10.102…
Check out our paper on proton pump inhibitor activation in cells in @NatureChemistry. Congrats to first author Teresa Marker who started this project in my group and finished it with Tobias Dick (@RedoxDKFZ). More collabs between our groups @DKFZ to come! rdcu.be/eaDjn
🗞️ "Characterization of conformational states of the homodimeric enzyme fluoroacetate dehalogenase by 19F–13C two-dimensional NMR" ⤵️ @UofT &+ With #NSERCsupport.
🗞️ "Characterization of conformational states of the homodimeric enzyme fluoroacetate dehalogenase by 19F–13C two-dimensional NMR" ⤵️ @UofT &+ With #NSERCsupport.
Congrats to Motasem in the #Prosserlab and our recent co-supervised alumnus @geordifrere for publishing a new story on tryptophan-based 2D 19F-13C NMR in @rsc_chembio!
Congrats to Motasem in the #Prosserlab and our recent co-supervised alumnus @geordifrere for publishing a new story on tryptophan-based 2D 19F-13C NMR in @rsc_chembio!
We're hiring a #postdoctoral Fellow in #medicinalchemistry in collaboration with @HDAXtx! Please repost and apply below if you're interested in advancing our novel small-molecule therapeutics! #chemjobs #chempostdoc #postdoc #postdocjobs @ChemPostdocBot linkedin.com/jobs/view/3992…
pharmacophore-optimized photoaffinity fragments-based hit discovery with improved hit rate and better sensitivity, and multiple binding sites, reported by @keserulab @GunningLabUofT nature.com/articles/s4200…
Congratulations to our Sr. Researcher Associate @GeletuMulu for receiving the Rosemary Brown Outstanding Mentorship Award at @CanBlackSci's #BlackExcellenceInSTEMM conference!! Mulu's commitment to scientific mentorship in our community is nothing short of inspiring. #BESTEMM2024

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American Society for ... @ASPhotobiology
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