Jetix Biotherapeutics @JetixBio
Joined April 2018-
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A cautionary tale for scientists dipping their toes into fields in which they don't have the relevant expertise. Model systems don't answer all questions equally well and can give misleading and dangerous results.
A cautionary tale for scientists dipping their toes into fields in which they don't have the relevant expertise. Model systems don't answer all questions equally well and can give misleading and dangerous results.
Impact of donor source on allogeneic hematopoietic stem cell transplantation for mature T- and NK-cell neoplasms in the Kyoto Stem Cell Transplantation Group. by Watanabe M, Kanda J, Arai Y, Hishizawa M, Nishikori M, Ishikawa T, Imada K, Ueda Y, Akasaka… ift.tt/3k54W4Q
Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge dlvr.it/RZGKRz
Wait, what? A subset of #gdTcells can specifically respond to tissue culture-treated plastics? Has previously been recognized as „spontaneous“ activity...wonder about physiological ligands...maybe polyanionic PAMPs or DAMPs? @forum_gd @JosefineDunst @jlb_journal
All we need is a cocktail!🍹
I hesitate to admit this but here goes: Cancer made me a better person. I take fewer things for granted now, especially my health. I’m more likely to tell my loved ones they’re precisely that. And every morning I’m grateful to open my eyes again. #CancerSurvivorDay
This is awesome and thank you for sharing the raw data! That’s very exemplary!
This is awesome and thank you for sharing the raw data! That’s very exemplary!
Intratumoral γδ T-cell infiltrates, CCL4/5 protein expression and survival in patients with hepatocellular carcinoma. by Zhao N, Dang H, Ma L, Martin SP, Forgues M, Ylaya K, Hewitt SM, Wang XW ift.tt/2AOT3xJ
Wonderful study on dendritic cell diversity & plasticity in viral infection on single cell level. Congrats @MartinGuilliams and @bart_lambrecht labs! Inf-CD64+ & IRF8+ conventional type-2 DCs arise to activate CD4+ & CD8+ T cells. And, they are not moDCs! cell.com/immunity/fullt…
Next up from TC Biopharm: allogeneic gamma-delta Car-T (TCB003-006), based on claim that healthy cells don’t express IPP #CARTCREU
Michael Leek (TC Biopharm) reckons gamma-delta T cell based allo product could get cost of goods down to $5,000/pt #CARTCREU
Review on NK cell homeostasis and subset heterogeneity by @AlinePfefferle and team based on her thesis at @karolinskainst
Today, @Incysus announced that we treated the 1st patient in our phase I #cancer trial for #leukemia and #lymphoma patients. It's a 1st for #allogeneic #gdTcells! Thanks to the great team @KUcancercenter helping patients during this challenging time! bit.ly/2AqlCSh
Depletion of innate immune cells such as NK cells, gamma delta T cells, pDCs as previously reported. A highly heterogeneous induction of an ISG signature across multiple immune cell types.
Good review from @NatRevDrugDisc of gamma delta T cells in cancer #CellTherapy γδT cells display potent cytotoxicity towards a large array of hematological and solid tumors, while preserving normal tissues. Sept '19 Paper (open access): nature.com/articles/s4157…
gd T cell game.
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