TIMI Study Group @TIMIStudyGroup
Providing the latest news and research from the TIMI Study Group, an ARO affiliated with Brigham and Women’s Hospital and Harvard Medical School. timi.org Boston, MA Joined September 2013-
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GOLDILOX-TIMI 69 results now in Nat Med. No effects of LOX-1 inhibition on coronary plaque volume. @DrM_ODonoghue nature.com/articles/s4159…
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TIMI Study Group retweeted
Fueled by thoughtful questions from @AliceYYCheng, I had the honor of engaging in a fun and insightful discussion on our recent FOURIER-T1DM project! @TIMIStudyGroup #LawrenceLeiter #MarcSabatine
Fueled by thoughtful questions from @AliceYYCheng, I had the honor of engaging in a fun and insightful discussion on our recent FOURIER-T1DM project! @TIMIStudyGroup #LawrenceLeiter #MarcSabatine
In patients with atrial fibrillation on VKAs, the #DOAC Score stratified risk for major bleeding and showed stronger predictive performance than HAS-BLED, with modest overall discrimination. @RahulAggarwalMD @rgiugliano #ESCCongress
Abelacimab consistently reduces bleeding vs. rivaroxaban irrespective of CrCl or rivaroxaban dose reduction. @SidPatelMD #ESCCongress Full manuscript available at: jamanetwork.com/journals/jamac…
OAC-naïve patients experience higher rates of bleeding. In #AZALEA-TIMI 71, #abelacimab consistently reduced major/CRNM bleeding vs. rivaroxaban irrespective of prior OAC status or type of OAC (DOAC or VKA). @SidPatelMD #ESCCongress
In AFib pts ≥80 yrs meeting dose-↓ criteria, pts randomized to edoxaban 15 vs. 30 mg had comparable rates of stroke/SE. Edox 15 mg led to a trend toward ↑ ischemic strokes but ↓ major & intracranial bleeds; supported by PK/PD analysis. @AndreZimerman @rgiugliano #ESCCongress
Dr Eugene Braunwald’s most recent review in @NEJM nejm.org/doi/full/10.10…
See @SidPatelMD speak on renal function and factor XI inhibition in a pre-specified analysis of AZALEA-TIMI 71, in 24 hours in Science Box 3 #abelacimab #ESCCongress
A validation of the DOAC score among COMBINE-AF patients on vitamin K antagonists will be presented by @RahulAggarwalMD, tomorrow at 2:30pm in Science Box 3 @rgiugliano #ESCCongress
Watch @SidPatelMD present his work on prior anticoagulation experience, bleeding risk, and safety of factor XI inhibition in atrial fibrillation: an analysis of AZALEA-TIMI 71, in 24 hours in Science Box 3 (Research Gateway) #abelacimab #ESCCongress
Dr. Andre Zimerman presents his work on low-dose #edoxaban in patients 80 years and older with AF and dose-reduction criteria, tomorrow at 1:15pm in Science Box 4 (Research Gateway) @AndreZimerman @rgiugliano #ESCCongress
In 24 hours, see the COMBINE-AF presentation, "Regional differences in clinical outcomes in patients of Asian race with AF randomized to direct oral anticoagulants vs warfarin", Station 5 (Research Gateway) @rgiugliano #ESCCongress
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