waking_up_dormancy @WDormancy
Tweeting about gene regulation and genomics studies related to senescence, aging, and cancer dormancy. Maintained by @mitramith @ucla Los Angeles, CA Joined June 2021-
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waking_up_dormancy retweeted
Chromatin basis of the senescence-associated secretory phenotype dlvr.it/SGsW8v
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waking_up_dormancy retweeted
Removing a key protein from the worm Caenorhabditis elegans near the end of its life can double the worm’s lifespan, demonstrating that life-extending interventions can be made at any age. elifesciences.org/digests/71335/…
waking_up_dormancy retweeted
Thrilled to share our latest publication out today in @NatureCancer! This work was led by talented postdoc @julieSdimartino with the help from members of the @BravoCorderoLab @CMondal01 and fantastic collaborators @NabaLabUIC, @FertigLab, @JAguirreGhiso! (1/4)
A single-cell transcriptomic landscape of the lungs of patients with COVID-19 #senescence #COVID19 @NatureCellBio nature.com/articles/s4155…
waking_up_dormancy retweeted
The lncRNA CYTOR protects muscle mass and fast-twitch fibers from the effects of #aging in mice and humans, suggesting the RNA could be a target for gene therapies and other interventions aimed at treating #sarcopenia in the elderly. @EPFL_en @Auwerx_Lab fcld.ly/d90t8tw
waking_up_dormancy retweeted
Extremely excited to share my first (co)first-author paper! Some people get cancer at a younger age while others do not. We identify widespread molecular differences associated with age across tumors. Massive effort led by @ElementoLab and @AkankshaVe cell.com/cell-reports/f…
waking_up_dormancy retweeted
The literature is full of claims for diets that delay or reverse the aging process—at least in lab animals. But how do these interventions work? A new #ScienceReview explores the fact and fiction of dietary prescriptions for a healthier and longer life. fcld.ly/5cjgpvp
waking_up_dormancy retweeted
Helpful slide from @NIH for budding scientist in aging/geriatrics. #NIA #Beeson2021 #BeesonScholar @AFARorg
waking_up_dormancy retweeted
Our work on a seemingly unique #3Dgenome reorganization mechanism that drives escape of cells from #senescence is now out in @MolecularCell: an amazing collaboration with the Gorgoulis lab (@uoaofficial) and @Bartek_Lab. Short 🧵 follows — ideas welcome!
Our work on a seemingly unique #3Dgenome reorganization mechanism that drives escape of cells from #senescence is now out in @MolecularCell: an amazing collaboration with the Gorgoulis lab (@uoaofficial) and @Bartek_Lab. Short 🧵 follows — ideas welcome!
waking_up_dormancy retweeted
How do we age? It remains a mystery, but former Amon lab postdoc @JetteLeng suspects it has something to do with the size of stem cells. In this video, she describes the findings of a new study published today in @ScienceAdvances. @ScienceMIT @kochinstitute @BIOTECH_UH
waking_up_dormancy retweeted
Cell size is a determinant of stem cell potential during aging science.org/doi/10.1126/sc…
The right time for senescence #review #senescence @eLife doi.org/10.7554/eLife.…
waking_up_dormancy retweeted
Excited to share our collaboration profiling human lung aging from the Bhattacharya Lab (UCSF), Wolters Lab (UCSF), Bhattacharya Lab (Columbia), which just came out today in Nature Communications! rdcu.be/cAElz #LungAging #Fibrosis #LungHealth #Senescence #Aging
Origins and evolution of extreme life span in Pacific Ocean rockfishes @ScienceMagazine science.org/doi/10.1126/sc…
waking_up_dormancy retweeted
Adults with lower education are at higher risk of Alzheimer’s Disease. What brain changes lead to this vulnerability? We have some answers in a new @NatureAging paper, which reveals a brain network-based biomarker that is prognostic of dementia rdcu.be/cBemK /n
waking_up_dormancy retweeted
Increased fidelity of protein synthesis extends lifespan dlvr.it/SBqKP3
waking_up_dormancy retweeted
A gene toolbox for monitoring autophagy transcription nature.com/articles/s4141…
waking_up_dormancy retweeted
People who live beyond 105 years tend to have unique genetic signatures that make their bodies more efficient at repairing DNA elifesciences.org/articles/57849…
waking_up_dormancy retweeted
When the PIs are coming to check on the lab. @LabDeNicola @KarrethLab
waking_up_dormancy retweeted
When you tell an 'omics lab to dress up for Halloween.. @doctorcorces
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