WilsonLab @WilsonLab2
Ribosomes & Translation Regulation; Antibiotics & Resistance Mechanisms; Structural Biology & Cryo-EM; University of Hamburg. chemie.uni-hamburg.de/bc/wilson Hamburg, Germany Joined June 2018-
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WilsonLab retweeted
New online! Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug bit.ly/4mluP07
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WilsonLab retweeted
Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @NatureSMB🥳rdcu.be/eBbrH Massive team effort led by @leonie_anton @mehsehret @Wenjing_Cheng_ in collaboration with @DziekanJerzy @CowmanAlan #teamtomo
WilsonLab retweeted
Out Now! Deep learning reveals antibiotics in the archaeal proteome bit.ly/4lpohMM #DeepLearning #ArtificialIntelligence #Antibiotics
WilsonLab retweeted
What is a PhD?
WilsonLab retweeted
Our RAPPL purification of ribosomes and associated material is finally out. I am really proud of this study in collaboration primary with @slavicaPD lab, as well as Marko Jovanovic and @Hashemyaser4 Labs. This method aims to replace 60 years old purification of ribosomes by…
WilsonLab retweeted
Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: biorxiv.org/content/10.110…
WilsonLab retweeted
We are excited to share our latest research on Q-modification in precursor-tRNAs, which just got published in @NatureComms. This was an very exciting and fruitful collaboration with @francescatuorto in Heidelberg. nature.com/articles/s4146…
WilsonLab retweeted
How many plasmids can bacteria carry? A synthetic biology perspective doi.org/10.1098/rsob.2…
WilsonLab retweeted
Out Now! Structure of an archaeal ribosome reveals a divergent active site and hibernation factor bit.ly/3UhiSfp #Archaea #RibosomeStructure #PeptidylTransferase
Preprint from our collaboration with the labs of Gerry Wright and Shura Mankin @shuramankin identifying the first translation inhibitor binding to the E-site of the bacterial ribosome… researchsquare.com/article/rs-692…
WilsonLab retweeted
New paper out in Mol Cell, where we show how N-myristolytransferases lipidate proteins on the translating ribosome! Continuing our successful collaboration with @DeuerlingLab & Shu-ou Shan @Caltech @snsf_ch @ETH_en cell.com/molecular-cell…
WilsonLab retweeted
Thrilled that Patrick Cramer @mpgpresident was elected a Foreign Member @royalsociety, here at today's event! 🥳Congratulations also to Max Planck appointees Miltos Tsiantis @mpipz_cologne , elected as Fellow, Detlef Lohse & Claudia Felser @mpi_CPfS - science is international!😊
WilsonLab retweeted
Mammalian tRNA acetylation determines translation efficiency and tRNA quality control doi.org/10.1038/s41467…
WilsonLab retweeted
@DjuranovicLab is from today officially part of @BrownUniversity and Brown RNA center. We will have our new website soon. rna.brown.edu
WilsonLab retweeted
Time-resolved cryo-electron microscopy can resolve protein motion on millisecond or even microsecond timescales, but the need for highly specialized tools and skills limits the method’s reach nature.com/articles/d4158…
WilsonLab retweeted
With our RTI colleagues Xiaobin Ling and @WenwenFang2, we report cryo-EM structures of enigmatic bacterial RNA nanocages made of long-noncoding ROOL RNAs. Octamers are held by "A-minor staples" and other interactions. Congrats Xiaobin, Dima et al! nature.com/articles/s4158…
WilsonLab retweeted
Activation of Retron-Septu for antiphage defense. Congrats @futianmin and all co-authors! science.org/doi/full/10.11…
Doudna super computer :)
Designing New Chimeric Proline-Rich Antimicrobial Peptides to Enhance Efficacy Toward the ESKAPE+E: Beyond Sequence Extension mdpi.com/2218-273X/15/6…
WilsonLab retweeted
Congratulations! The #ShawPrize in Life Science & Medicine 2025 is awarded to Wolfgang Baumeister for his pioneering development & use of cryo-ET. ❕shawprize.org/laureates/2025… @ShawPrize #CryoEM #cryoET #Award
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