Aldridge Lab @aldridge_lab
Lewy Body Dementia Research Lab: Cross-posts to @[email protected], facebook, @aldridgelab.bsky.social and threads. aldridge.lab.uiowa.edu Joined March 2019-
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Higher regional alpha-synuclein levels in cortex lead to increased survival of new spines in nearby neurons- We used awake imaging following transduction to track the process! link.springer.com/10.1007/s10571…
Excited to be an author on this study in JAMA. We're in a new era of detecting neuropathology in living patients! We are already using this in clinic to detect alpha-synuclein (the protein associated w/Parkinson's disease and Lewy Body Dementia) in skin. jamanetwork.com/journals/jama/…
Proud of all we've accomplished this year - and even prouder of the things we've got cooking for the future @aldridge_lab @iacobus42
Excited to get tweeted about! Less excited to spot a typo… maybe this is the European spelling of LC :-) But great visibility for the Smash Dementia! Team. @marcinkiewczlab @iacobus42 @Prof_BBaran
Excited to get tweeted about! Less excited to spot a typo… maybe this is the European spelling of LC :-) But great visibility for the Smash Dementia! Team. @marcinkiewczlab @iacobus42 @Prof_BBaran
Gave a talk at #wpc2023 today as a plenary. That’s tiny me in the bottom right corner speaking about co-pathologies.
Our newest preprint up on biorxiv: biorxiv.org/content/10.110… Data: narayanan.lab.uiowa.edu/article/datase… with @aldridge_lab TLDR: Rodent PD models don't always work as advertised
Your gift on #1DayforIowa helps fund research into Lewy body and Parkinson's dementia in the Aldridge Lab! givetoiowa.org/lewy Here you see pathological aggregates of a-synuclein (pink) filling a neuron in a person with severe dementia.
6/8 Because of the known variability of Abeta load in transgenic mouse models of AD we tested the effects of acute & chronic visual flicker, genetic background, sex & age to identify a treatment window. There were no significant changes in Abeta levels in any of these conditions.
Please re-Tweet this reason why hospitals must allow family caregivers to be present when people with #Alzheimers disease and other forms of #dementia are being evaluated or receiving treatment and care.
For streamlined, tax-deductable donations to support earthquake search&rescue, relief and recovery efforts please consider @tphilanthropy . Your donations are matched by @hamdiulukaya, founder of @Chobani donate.tpfund.org/campaign/tpf-t…
Dear friends and colleagues from all over the world. My beautiful country suffered from a series of earthquakes with devastating consequences. Please consider donating to humanitarian aid organizations. #TurkeyQuake gofundme.com/f/xh8d5t-turke…
Trying out Mastadon and testing to see if I get thrown off twitter for the link (I heard they flip-flopped on banning links to cage us in). Find me here: @[email protected]
The searing wordplay in this editorial 💎 on #delirium speaks to my soul 🫠 His nurse calls him ‘pleasantly confused’. As if he could be. The pressure to discharge mounts, and so does the tension between teams. We can all be...less confused by delirium. doi.org/10.1111/acps.1…
Join us in the new Center for Neurodegeneration at the University of Iowa: jobs.sciencecareers.org/job/637399/ten… medicine.uiowa.edu/neurodegenerat… Work with amazing colleagues, an innovative environment, a vibrant Iowa Neuroscience Institute, and rich clinical collaborations. @UIowaNeuro
Thank you to all current and former @geerling_lab members, our collaborators, donors, funding agencies, and the many, uncredited patients who inspire and inform our work. Science is a team sport, and we are nothing without you.
Gabi Gryc showing off her direct hit to locus coeruleus with alpha-synuclein fibrils and a lot of new-to-us circadian/arousal assays. Great first SfN poster!
Lewy body is more than memory. Come see the trials and tribulations of developing complicated cognitive flexibility tasks, including with head-fixed mice. @_r_a_dean 1st poster.
Aldridge lab at #SfN22 - specifically the Friends of Iowa INI social at another nice venue! Almost feels like 2019 again.
@SfNtweets, who is awake at #SfN2022? Riley Dean & colleagues from @aldridge_lab are using #2photonmicroscopy in #awakemice combined with a new behavioral task to study how alpha-synuclein overexpression in the prefrontal cortex affects cognition. Poster 704.28, Nov 16th.
Ventura's Lab @PPMC_UAB
2K Followers 795 Following Protein Folding and Conformational Diseases Lab at @IBB_UAB in @UABBarcelona Group leader: Prof. Salvador VenturaHammad Khan @Hammad_FKhan
124 Followers 205 Following PhD Graduate Student | Neuroengineering🧠 | Motor Learning and Cortical Circuits | Purdue UniversityPoonam Thakur @poonam_thakur6
9K Followers 2K Following Assistant Prof @tvmiiser & @India_Alliance fellow. Interested in the neuroscience of Parkinson's disease. Now on https://t.co/OZExaDgDbXDSHB @DSHB_antibodies
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108 Followers 502 Following Associate Professor, Department of Biophysics @NIMHANS_BLR | Research interest: Chromatin Structural Biology and Neurodegenerative diseasesIowa Neurology @IowaNeurology
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27 Followers 99 Following Genetics PhD student @uiowa studying metabolism of the aging and Alzheimer's Disease brain in the Potthoff Lab | 🇨🇴Ewa Bomba-Warczak @bomba_ewa
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13 Followers 55 Following https://t.co/VTRhAS7OKZ in Biomedical Engineering from BUETAnalia Bortolozzi @aabortolozzi
671 Followers 792 Following Neuroscientist. Group Leader #CIBERSAM #depression #Parkinson #stress #anhedonia #oligonucleotides #genetherapy #bortolozzilabNour Shaheen @NourSha66166879
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4K Followers 917 Following MD PhD, Therapeutic Area Leader for Movement disorders at @Roche Expert on #Parkinson and #Huntington disease. Views expressed here are my own.Kanjear david Kamara @KanjearD
21 Followers 235 FollowingAnna Carver @DNAnnacarver
115 Followers 261 Following Genetics PhD Candidate @uiowa studying placental genetics impact on fetal brain 🔬 in the @PsyNeuroDevLabMASSIMILIANO IACHINI @Massi_I
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211 Followers 384 Following Mass spectrometry/Proteomics @RUB @ProteomCenter Neuromuscular disorders (MFM, DMD) Neurodegeneration (PD), Neuromelanin granules, Protein aggregationMax Wulf @MaxWulf13
140 Followers 303 Following PhD-student at @ProteomCenter of @ruhrunibochum, interested in #proteomics, #masspectrometry, #neurobiology and #neurodegenerativediseasesSivakumar Srinivasan @Sivasrinivasan_
62 Followers 221 Following PhD student @MedUni_Wien 🧠 Neuroscience, Engineer, Trekker.alex.bova @alexbova9
125 Followers 367 Following Systems neuroscientist studying the role of dopamine in cognition and movement in @narayananlab at @UIowaNeuro. Postdoctoral fellow @INSPIRE_iowa. PhD @umichKalpana Gupta @kalps_gupta
16 Followers 75 Following Postdoc researcher/Parkinson’s disease/PhD Systems Neurophysiology/Prediction signals/Understanding the mysteries of brain/Expanding horizonsMaddie Mix @Mix_Maddie
183 Followers 400 Following @Iowa_MSTP MD-PhD candidate | Studying brain-resident memory T cells | She/her 🩺🔬Ian Kremer @LEAD_Coalition
67K Followers 47K Following Working to end #Alzheimers/#dementia. @WUSTL @UMichLaw https://t.co/GJkJVm4vF2 https://t.co/dd0eOpRj6V https://t.co/1ARWoHKsQuJared Shelerud @JaredShelerud
45 Followers 399 Following These are facts based on opinion, views are my ownMilagros Galecio-Cast.. @mili_galecio
305 Followers 1K Following Aspiring physician scientist & biostatistics enthusiast 🏳️🌈🇵🇪🇺🇸 | Teamwork | “The one who only knows about Medicine, does not even know about Medicine”Hannah Van Ert @hanbanan_V
135 Followers 797 Following 💉RN BSN '15 UW-Madison 🔬M5G MD/PhD trainee UIOWA 🦠Immunology grad student studying Ebola Virus infection in pregnancy 🐱Cat co-habitator *tweets are my own*MelodyDean @mpdean0906
96 Followers 197 FollowingUI Stead Family Depar.. @UIowaPeds
1K Followers 2K Following The people powering @uichildrens and @iowamed | Here to talk about the #research and #education that goes into growing our talent @uihealthcareEmese Kovács @KovacsEmeseHC
86 Followers 160 Following PhD candidate| Gaine Lab University of Iowa, Department of Neuroscience and Pharmacology Chair of Travel Funds Committee, Graduate Student SenateTimothy Skog @tdskog
131 Followers 220 Following Behavioral Neuroscientist 🧠. Stress neurobiology. Science Communication. PhD Candidate @IowaNeuro. Hiking 🥾. Cooking 🔪. Music-ing 🎹 🎻Jason Radley @RadleyLab
34 Followers 18 FollowingIzaque Maciel 🇧�.. @maciel_izaque
207 Followers 581 Following Researcher Associate at Charles River Laboratory - kuopio |Researcher studying the role of stress, early life adversity and Biomarkers in psychiatric disorders|GP_Selva Kumar @SelvaKumar_gp
10 Followers 85 FollowingGergő A. Nagy @nagyatgergo
524 Followers 2K Following Researcher interested in the neurobiology of learned &innate behaviors; main expertise: in vivo ephys, optogenetics & behaviorSeth Tomchik @TomchikLab
1K Followers 1K Following Neuroscience of neuronal plasticity and implications for learning, neurofibromatosis type 1, and metabolic regulation. Views my own.University of Iowa Pe.. @uiowapedsneuro
501 Followers 780 Following Official account of the Division of Child Neurology. Improving patient lives through excellence in clinical care, research, & education. #neurotwitter @uiowaRobert J Taylor Jr @RobertJTaylorJr
27 Followers 90 Following Neurobiologist | Teacher | Mentor | Cat DadSamuel Kohtala @samuelkohtala
586 Followers 752 Following "Neuropharmacist", postdoc, personal views only - studying ketamine, psychotropic drugs, neuroplasticity, antidepressant treatments || - ENG/FINAlper Olcal @futurist_md
128 Followers 734 Following Dallas/Volunteer at UTSW and ICNA free clinic Georgetown American University Graduate 2020’ Atlanta/GASamual Hatfield @SamualJHatfield
133 Followers 119 Following @iowamstp MD/PhD M2 Student | @ui_ventures Iowa Innovations Fellow | Cancer, Cell Therapies, Material Science | First Gen • Father • Veteran | Opinions my ownC. Andrew Frank @CAndrewFrank
3K Followers 3K Following Husband, dad to 3, son, brother, uncle, cousin, nephew. Fruit fly neuroscientist, geneticist. Associate Professor, University of Iowa. He/him. Tweet = my view.Smash_Dementia @smashdementia
5 Followers 7 Following A collaboration of Iowa Neuroscientists to unlock the pathobiological origins of Alzheimer's disease and Lewy Body Dementia.Ewa Bomba-Warczak @bomba_ewa
1K Followers 2K Following Rising Assistant Professor at @UPennPhysiology | K99/R00 #NIHMOSAIC Scholar | @LeadingEdgeSymp Fellow | @MitOtalks /chat co-org | long-lived mitochondria 💪Irina Skylar-Scott @iskylarscott
867 Followers 3K Following Trying to find good in the world. Trying to do some good. #Alzheimers. Formerly @MIT, @YaleMed, and @HarvardMed. Currently behavioral neurologist @Stanford. 🧠ScienceofParkinsons @ScienceofPD
10K Followers 266 Following Personal account of the Director of Research at @CureParkinsonsT - All views my own - Kiwi - Kia kaha - 侘寂alex.bova @alexbova9
125 Followers 367 Following Systems neuroscientist studying the role of dopamine in cognition and movement in @narayananlab at @UIowaNeuro. Postdoctoral fellow @INSPIRE_iowa. PhD @umichBengi Baran @Prof_BBaran
138 Followers 142 Following Neuroscientist • Sleep Researcher • PI of @IowaNap • progressive • feminist • mom • former Istanbulite & Bostonian, newly minted Midwesterner • views mineKalpana Gupta @kalps_gupta
16 Followers 75 Following Postdoc researcher/Parkinson’s disease/PhD Systems Neurophysiology/Prediction signals/Understanding the mysteries of brain/Expanding horizonsUniversity of Iowa Ce.. @UIAdvancement
13K Followers 13K Following If you love the University of Iowa, we can keep you connected through engagement and philanthropy. #AlwaysAHawkeyeSingh Lab @singhlab_usd
77 Followers 137 Following Studying motor function and cognitive control in people with Parkinson’s disease at the University of South Dakota.Jason Radley @RadleyLab
34 Followers 18 FollowingSeth Tomchik @TomchikLab
1K Followers 1K Following Neuroscience of neuronal plasticity and implications for learning, neurofibromatosis type 1, and metabolic regulation. Views my own.Marie Gaine 🐘 @MarieEIrish
444 Followers 694 Following Assistant Professor in the College of Pharmacy UIOWA, Irish native, Iowa transplant, Lover of wine. She/her.Kishore Kuchibhotla @kishoreneuro
905 Followers 349 Followingneurodelirium @neurodelirium1
166 Followers 267 Following A group comprising international interprofessional stakeholders, simply with the goal of fostering robust discussion of the neural basis of delirium.Niciu Lab @NiciuLab
158 Followers 171 Following Translational/clinical neuroscience laboratory investigating the pathophysiology and treatment of major mood disorders and their comorbidities.Kaancan Deniz @kaancandenizmd
206 Followers 419 Following Neurology Chief Resident (PGY-4) @uihealthcare @uiowa @iowaneurology Incoming Behavioral Neurology Fellow @UCSFmacKenya Barnes (she/her.. @kenyabarnes_
117 Followers 284 Following uab ‘24 || loves Beyoncé and scienceVirginia Gao @virginia_gao
243 Followers 225 Following Movement disorders fellow @CUMCNeurology @WCMCNeurology researching alpha-synuclein @WCM_BMRIDr. Malu Tansey @MaluTansey
7K Followers 5K Following Stanford, UTSW, Latina, mother, daughter. Immunity inflammation lysosomes neuroimmuno neurodegen, EIC NPJPARKD, Prof, Parkinson’s GRC Chair 2023. Tweets my own.Sara Elfarrash @ElfarrashSara
1K Followers 734 Following MD PhD👩⚕👩🔬, Assistant Professor, Faculty of Medicine, @Mansoura_un. Neuroscience, Investigating Protein aggregation and neurodegenerative disease🧠Neil Chatterjee @NeilChatterBox
282 Followers 390 Following Post-doctoral Fellow @NUFeinbergMed | #neuroscience #neurodegeneration #therapeutics | news/sports/food/travel/debate junkie | Diptaman by day, Neil by nightLiesl Close MD @CloseLiesl
364 Followers 197 Following Assistant Professor of Neurosurgery at UCSF. Iowa NSG, Ohio State Spine, Miami Neurotrauma & Critical Care. Wife, Mom, lover of the outdoors.Dr Cara Croft @Cara_Croft
3K Followers 2K Following Senior Lecturer @blizard_inst @QMUL & @RacingDementia Fellow: Alzheimer’s, Parkinson's, AAV // Travelling, turtles, & tea. Views my own. #FirstGen #WomenInSTEMAaron Boes @boeslab
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1 Followers 36 FollowingMarcinkiewcz Lab @marcinkiewczlab
186 Followers 194 Following Unraveling brainstem circuits in neuropsychiatric disorders and Alzheimer's disease.Hannah Stutt @StuttHannah
93 Followers 99 Following Neuroscience grad student at @UiowaNeuro studying sex differences in substance use and cognition @narayananlab | MKE native, go bucks 🦌Eric Landsness @EricLandsness
670 Followers 386 Following Sleep neuroscientist and neurologist. Interests: sleep, OSA, hypoglossal nerve stim, stroke, optical imaging, Alzheimer's. MD PhD Neurologist at WashU St Louis.Matt Weber @MatthewWeberPhD
86 Followers 139 Following Neuroscientist studying dopamine and cognition in @narayananlab at @UIowaNeurorafael yuste @yusterafa
14K Followers 245 Following news about our research, neurotechnology and science advocacy. follow also @neuro_rights @neuroderechos @Columbia_NTCAmerican Delirium Soc.. @AmerDelirium
4K Followers 350 Following The American Delirium Society aims to foster research, education, advocacy & implementation of evidence to minimize delirium's impact. #AmerDeliriumResearchDelirium Care Network @DeliriumCare
3K Followers 964 FollowingEuropean Delirium @EDA_delirium
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4K Followers 3K Following Network for Investigation of Delirium: Unifying Scientists (R33AG071744). Collaborative network developing resources to enhance #delirium research worldwide.Ergun Uc @ergunuc
54 Followers 73 Following father, husband. Neurology professor, Parkinson’s disease doctor & researcher, bicyclistMichelle Voss @vosshbc
555 Followers 352 Following #ExerciseNeuroscience, brain aging, health behaviors, cognitive neuroscientist, Assoc Prof, Director of HBC lab, mentor; mom, bikes, writing, outside adventuresDr. Monica M. Bertagn.. @NIHDirector
183K Followers 122 Following Official account of the @NIH Director Posts prior to 11/9/23 were from former NIH Directors Engagement ≠ endorsement Privacy: https://t.co/GijpA0bFOxOpenBehavior @OpenBehavior
4K Followers 301 Following OpenBehavior provides a centralized repository of open-source tools specific for behavioral neuroscience research [email protected]Jacob Simmering @iacobus42
330 Followers 1K Following Assistant Professor - Carver College of Medicine @[email protected]Alberto Serrano-Pozo @AlSerranoPozo
173 Followers 227 FollowingAlex Bassuk, he/him/t.. @AlexBassuk
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122 Followers 223 Following Asst Prof & neuroscientist in scenic Wyoming. Circadian circuits, biological/behavioral timing, dysfunction underlying "sundowning" in Alzheimer's. Views = mineRainbo Hultman @brainbolab
817 Followers 1K Following Neuroscientist: probing electrical brain networks in search of better therapeutics for debilitating disorders; e.g. #migraine, #depressionEyal Kimchi, MD, PhD @ekimchi
466 Followers 429 Following Studying brain networks & rhythms that support clear thinking and how to help people suffering from #delirium https://t.co/qOPDJCaNHD (he/him)Banu Gumusoglu @BanuGPhD
250 Followers 370 Following Assistant Prof @ University of Iowa, Ob/Gyn, Psychiatry. Opinions are mine. She/Her/Dr/Mom @banugphd.bsky.socialecneicsodreN @ecneicsodreN
195 Followers 46 FollowingBlack In Neuro 🧠 @BlackInNeuro
30K Followers 245 Following Highlighting Black excellence in all 🧠-related fields. Important links here: https://t.co/OhWkVnZdqFViktoria Korzhova @NeuroViktoria
267 Followers 260 Following Neuroscience PhD & Product Manager. Co-founder of English #scicomm landscape in Munich - team lead @15x4Munich, ex @munichsoapbox, ex @pintofscienceDEAislinn Williams @AJWilliamsLab
306 Followers 184 Following Asst Prof and Vice Chair for DEI at #UIHC Psychiatry. Iowa Neuroscience Institute. Behavior/neuroscience/iPSCs/genetics. she/her 🏳️🌈@BrookeYeagerMS @eic_nic Congrats to @BrookeYeagerMS on the first paper from her PhD: sciencedirect.com/science/articl… Check out her tweetorial describing functional connectivity impairments that are correlated with cognitive disfunction in PD! Data and code: narayanan.lab.uiowa.edu/article/datase… (data is mostly from PPMI)
Our Acta Neuropathologica paper is out! rdcu.be/dDBro We show that MAO-B is a worthy target for #PETimaging of reactive #astrocytes in #Alzheimers. Congrats to @MethasitJsa, @Claramc19 & Molly Healey! Thx to @PMAC2015 @RCC_Harvard @TofflerTrust @NIHAging & more #funding
Proud of all we've accomplished this year - and even prouder of the things we've got cooking for the future @aldridge_lab @iacobus42
Lila Peltekian is back! If you’re here at #SfN and interested in thirst, sodium appetite, and the renin-angiotensin system, check out her poster this afternoon (KK11).
.@HarmsLabUAB, bad ass neuroimmunologist @uab_neurology, talking about the role of neuroimflammation in co-pathologies in Parkinson's disease @WPC
Time to start putting all the pieces of the puzzle together. The regions affected, the timing, the co-pathologies and more. Combine this talk by Walker @WorldPDCongress with Borghammer body vs brain 1st and we are getting closer to clarity in a previously murky world.
‘Brain first’ vs. ‘Body first’ Parkinson’s. One of the most important talks #wpc2023 by Borghammer. This helps us understand symptoms, presentations, pathology, imaging and asymmetry. Time to update the Braak hypothesis of Parkinson’s. @ParkinsonDotOrg
@Lauren_C_Walker @NeuroNCL And she finishes by pointing out that there are very few therapies in clinical trials for #Parkinsons focused on co-pathology situations by comparing McFarthing et al (content.iospress.com/articles/journ…) vs Cummings et al (alz-journals.onlinelibrary.wiley.com/doi/10.1002/tr…)
Taking detailed patient information and studying them at the bench will allow us to further understand the underlying mechanisms that lead to co-pathologies in cognitive and non-motor symptoms @aldridge_lab
Giant Synapse update 18 speakers confirmed We have short talk slots for grad students/post docs Meeting is free Nov 10-11 Synapses reign supreme Webpage to come Please RT @KateOCG @JasonSynaptic @SynapsesInSight @CAndrewFrank @HTB_soFLY @TedAbelneuro @PeriKurshan @NeuroBender
Time flies... over the past 5y, Maggie (soon to be Dr. Margaret Tish) built a highly successful project in my lab over the past 5 years. Next Wednesday (6/14) at noon, she will present her thesis defense in 2117 MERF. All are welcome!
Me trying to keep up with emails...
Congratulations, Maggie! @MargaretTish (and everyone else receiving a doctorate this morning @UIGradCollege)
Thrilled to receive this award! Thank you @UIowaNeuro for recognizing and investing in the potential of our research.
Congratulations to INI Early-Stage Investigator Award recipients Stephanie Gantz @GantzStephanie & Joel Geerling @geerling_lab. These awards support faculty in laying the groundwork for external funding applications. More details about their research: medicine.uiowa.edu/iowaneuroscien…
Happy to share that singhlab has opened another lab in the Sanford Neurology Department at the Sioux Falls campus with wireless EEG, fNIRS, APDM wearable sensors, and electrical stimulation systems.
I’m excited to present a recent publication with co-first author @SivakumarKartik from @narayananlab, with Ervina Tabakovic, @mayuoya12, @aldridge_lab, @johnsonpumc, @iacobus42! You can access it here: rdcu.be/c6KDT A brief🧵about the project: (1/n)
My Dad passed away last night. In addition to a loving father and husband, he was a remarkable man: professor of French, university administrator, musician, chef, animal lover. In hospice he had countless visitors, in person and virtual, from around the world. We will miss him.