GAAIN @alzGAAIN
Big data neuroscience platform connecting brain researchers worldwide through a federated Alzheimer's Disease data portal. gaain.org Joined March 2015-
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🧬For #NationalDNADay, we found a strong association between #Alzheimers risk allele APOEe4 and high levels of plasma neurofilament light and total tau in the #GAAINInterrogator Start your own analysis at gaaindata.org
We found a strong correlation of functional activities questionnaire (FAQ) scores >8 and elevated PET amyloid as well as a linear correlation between FAQ and #centiloids Data from @MayoClinic Study of Aging (and ADNI) can be requested via @USCLONI's IDA: ida.loni.usc.edu pic.x.com/jb1cdlqlio
April is #ParkinsonsAwarenessMonth and our latest #GAAINInterrogator analysis of two datasets shows that being male is a stronger risk factor for Parkinson's disease (orange) than Alzheimer's disease (blue) ♂️ Run your own preliminary analysis here: gaaindata.org
We did not find an association between traumatic brain injury (#TBI) and cognitive impairment, but there is an association between TBI and stroke, which is a risk factor for cognitive impairment 🧠 More on CVD risks after TBI: ncbi.nlm.nih.gov/pmc/articles/P… #BrainInjuryAwarenessMonth
In this #GAAINInterrogator analysis of three studies, we found a protective effect of hormone replacement therapy (HRT) in women age 50+ against cognitive impairment ♀️ More on the mechanisms in which HRT can influence cognition: ncbi.nlm.nih.gov/pmc/articles/P… #WomensHistoryMonth
Thank you to everyone who stopped by booth 42 with @AlzData at #ADPD2024 so far! Join us again today for live demos of the #GAAINInterrogator #datasharing platform with Dr. @JohnPappas10 at 10:40, 12:50, and 16:30 📈 Learn more about GAAIN: gaain.org
Thank you to @alzassociation, a founding member of the AD Data Initiative, and integral data interoperability partner via the @alzGAAIN data platform. Your collaboration and support are truly appreciated. #ADPD2024
Attending #ADPD2024? Learn more about GAAIN at booth 42 with @AlzData and join us for live demos of the #GAAINInterrogator platform at 10:40, 12:50, and 16:30 local time on Wednesday March 6 and Thursday March 7 🇵🇹
Attending #ADPD2024? Meet our members and partners at booth 42 to discuss research collaborations. Explore expert-led demos on #ADWorkbench and our partner's interoperable data platforms including @imi_epnd, @alzGAAIN, @HDR_UK, @DPUKDataPortal, and @VivliCenter.
Combining three studies in the #GAAINInterrogator, we see that male participants with a positive #amyloid PET scan correlate slightly more strongly with cognitive impairment than female participants 🧠 Start your own Interrogator analysis here: gaaindata.org/partners/onlin…
In this #GAAINInterrogator analysis, #AtrialFibrillation is associated with questionable impairment or worse (CDR≥0.5) in female participants rather than in male participants 🩺 Read more on possible links between AFib and dementia: jamda.com/article/S1525-… #HeartHealthMonth
This #GAAINInterrogator analysis shows high cognitive impairment risks with APOEe4 in white (NHW) and Black (NHB) Americans, but not in Nigerians, highlighting the importance of including diverse populations in clinical studies to #EndAlz, for #BlackHistoryMonth and beyond 🌍
🆕 Additional calibration datasets and software to transform tau PET measurements to the standardized universal CenTauR scale have been provided by the @MayoClinic Aging and Dementia Imaging Research (ADIR) lab! 📥 Download here: gaain.org/centaur-project
For #HeartHealthMonth, we found a strong association between myocardial infarctions (MI or #heartattack) and cognitive impairment (CDR≥1) in male participants represented in #GAAIN ❤️🩹 Read more on possible mechanisms linking MI to cognitive impairment: ncbi.nlm.nih.gov/pmc/articles/P…
Neuropsychiatric symptoms are said to be both risk factors and clinical markers of cognitive decline and #Alzheimers. Indeed, we found a strong association between #apathy and MMSE scores 24 and below in a #GAAINInterrogator analysis. 📑 Read more here: ncbi.nlm.nih.gov/pmc/articles/P…
A #metaanalysis of three Data Partners in the #GAAINInterrogator showed an association between coronary heart disease and #Alzheimers, similar to what the authors reported here: ncbi.nlm.nih.gov/pmc/articles/P… 🫀Check out GAAIN for your own analysis: gaaindata.org/partners/onlin…
The risk for cognitive impairment with hearing loss (blue) may be mitigated by the use of hearing aids (orange), as shown in this #GAAINInterrogator logistic regression and reported in this abstract: jamanetwork.com/journals/jamao… 👉Start your own analysis here: gaaindata.org/partners/onlin…
Thank you everyone for a collaborative year in #datasharing to #ENDALZ Get a head start on your 2024 goals by exploring existing #Alzheimers, #dementia, and #aging data sets at gaaindata.org 📈
Alzheimer's Associati.. @alzassociation
168K Followers 5K Following The Alzheimer’s Association is the leading voluntary health organization in Alzheimer's care, support and research. #ENDALZAlzforum @alzforum
11K Followers 340 Following A news and information resource website helping scientists advance AD research since 1996. Alzforum doesn’t endorse any specific product or scientific approach.Yakeel T. Quiroz, PhD.. @ytquiroz
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1K Followers 87 Following The Harvard Aging Brain Study (HABS) aims to elucidate the earliest changes in molecular, functional & structural imaging markers in preclinical #Alzheimers 🧠Happening now at #ADPD2024 Booth 42: 🔷 Dr. @JohnPappas10 providing demos for @alzGAAIN @alzassociation 🔷 Special booth guests from @IMI_EPAD @eufingers and @DavosAlzheimers Stop by during today's sessions to learn from our global data and platform partners
Stop by the booth this week to learn more about how @alzGAAIN and @AlzData are working together to help support the broader data sharing in the dementia science community (including live demos— plus there are cookies) #endalz #ADPD2024
Hello from #ADPD2024! Meet our partners from around the world and learn about the AD Data Initiative at booth 42 or online throughout the week. If you come by the booth, don't forget to grab a cookie.🍪
#ADPD2024 Day 2 is a wrap! It’s been a great day at booth 42: ✔️Platform Demos from @DPUK @alzGAAIN and @imi_epnd ✔️ #IMI_EPND co-leads Tony Brookes and @niranjanbose, with @AngeBradshaw_AE ✔️Data contributing partners @IMI_EPAD
Thank you to @alzassociation, a founding member of the AD Data Initiative, and integral data interoperability partner via the @alzGAAIN data platform. Your collaboration and support are truly appreciated. #ADPD2024
Hello from #ADPD2024! Meet our partners from around the world and learn about the AD Data Initiative at booth 42 or online throughout the week. If you come by the booth, don't forget to grab a cookie.🍪
Our interoperability partners are enabling the world of data sharing. Learn about the resources they offer by visiting booth 42 at #ADPD2024.➡️ bit.ly/3TiCMGf Meet our partners (🧵1/6)
Attending #ADPD2024? Meet our members and partners at booth 42 to discuss research collaborations. Explore expert-led demos on #ADWorkbench and our partner's interoperable data platforms including @imi_epnd, @alzGAAIN, @HDR_UK, @DPUKDataPortal, and @VivliCenter.
Aspects of @MRCLHA Insight 46 data are now on @alzGAAIN — see what’s available and how you can access data
One of our newest #GAAINDataPartners, Insight46 from @drcionucl and @UCLIoN, has extensive neuroimaging-derived data, including #Centiloid and #amyloidPET positivity. All participants were born in the same week in March 1946 🇬🇧 Check out Insight46: gaaindata.org/partner/INSIGH…
⏳ Time flies when you constantly have brains on the brain... Take a look at our summer 🏖️ & fall 🍂 newsletter to see what we've been up to: bit.ly/3uFiyha
@kevinmawright Try GAAIN @alzGAAIN for a federated data portal that has this data. (Although you have to apply to the owners for it).
We've got Thanksgiving on our brains🦃🧠 Wishing you all a happy holiday tomorrow surrounded by loved ones and enjoying delicious food! 🎊
We had a great time walking together to #ENDALZ 💜 in Hermosa Beach this past weekend ✌️🌷 Thanks to our faculty, staff, and students who participated, and thanks to @alzassociation for bringing so many people together 🤝🧠
We start #WorldAlzheimersMonth with a call for collective action. AD Data Initiative members and partners share how we can break barriers and streamline solutions, together, in this article: frontiersin.org/articles/10.33…
Authors of the article are from @alzGAAIN, @DementiasUK and ADDI, they include Arthur W. Toga, Mukta Phatak, @JohnPappas10, Simon Thompson, @c8linmch, Matthew Clement, Sarah Baumeister, Tetsuyuki Maruyama, and @John_ejg.
The donut wall has to be one of the best things AAIC has ever done 😭 #AAIC23
💪👩🔬 Our @alzGAAIN team member @scientificcally is rockin' booth 412A at #AAIC23! Stop by to learn more about #datasharing to end #Alzheimers! Sign up for free & easy access to discover clinical, genetic, imaging & other data collected across many independent studies🧠✌️
Director Arthur Toga and @susivak have a great chat about using @alzGAAIN for data sharing to end #Alzheimers at #AAIC23! 🧠🙌 Check out the GAAIN booth 412A 👀