Christian Benner @bennerstat
Statistician during daytime… finemap.me Helsinki, Finland and NYC, USA Joined September 2015-
Tweets57
-
Followers159
-
Following5
-
Likes47
Excited to share our latest manuscript in @NatureGenet! Utilizing high-resolution genetic data imputed with a population-matched reference panel, we uncovered causal genetic variants for a wide range of human traits over 200K participants from Japan (1/20) nature.com/articles/s4158…
Check out our latest findings on X-inactivation in iPSCs now out in Genome Biology genomebiology.biomedcentral.com/articles/10.11… A great collaboration with Dr Olli Pietiläinen and a cool demonstration of the many complexities of the X chromosome 😎
Matti’s course is a 💎
Work with us as postdoc in statistics / statistical genetics at University of Helsinki @helsinkiuni @FIMM_UH Apply by 21.5. jobs.helsinki.fi/job/Helsinki-P…
Extremely excited to share our work on #V2F method SCAVENGE for the disease/trait relevant causal cell type/state identification using single-cell epigenomic data nature.com/articles/s4158… out now in @NatureBiotech. The R package can be found github.com/sankaranlab/SC….
Variant to function mapping at single-cell resolution through network propagation go.nature.com/3NvBP9q
@gavinband Yes, it’s annoying. Maybe brew gcc8 and symbolic link would work?
Apart from COJO, FINEMAP also benefits substantially from DENTIST-based QC when an external LD reference is used. biorxiv.org/content/10.110…
Our UK Biobank mito-phewas is finally out! Great collaborative work. Congrats to @DoingYonova, Dr. Jo Howson, @auroradevea et al. Exciting times ahead for mitochondrial genomics! @cam_mito nature.com/articles/s4158…
Excited to share this preprint from the lab led by my talented postdoc Jaakko T. Leinonen (not on Twitter) where we used both UK Biobank and FinnGen data to comprehensively profile the role of testosterone in human health and disease. Thread 👇medrxiv.org/content/10.110…
Our paper (led by Pyry Helkkula & Ida Surakka) on lipid associated pLoFs and their impact on cardiometabolic risk is now out. Leading the pack is 80-times Finnish enriched PTV in ANGPTL8 gene. @PLOSGenetics @CoECDG @FinnGen_FI @FIMM_UH journals.plos.org/plosgenetics/a…
A highly Finnish enriched LoF in ANGPTL8 is associated with lower triglyceride levels, lower CAD risk but elevated risk for esophagitis in @FinnGen_FI. Also, lipid and PheWAS profiles for PTVs in ANGPTL4, LIPG and CETP. Work lead by Pyry Helkkula & Ida Surakka. @CoECDG @FIMM_UH
In our new paper we do in-depth follow-up of Alzheimer’s disease GWAS: integrating fine-mapping, colocalization, gene network analyses, and single-cell gene expression to prioritise risk genes. This figure would have better represented the work.
✨Online today @NatureGenet from Andrew Bassett @jschwart37 and colleagues: Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genes🧠🧬| go.nature.com/3u1G432
With FINEMAP, we identified >27,000 distinct signals in >5,000 regions across the 35 traits, of which >2,500 signals were fine-mapped to a single variant. We also trained sparse polygenic risk score (PRS) models with Lasso L1- penalized regression using the snpnet package. (4/n)
our hemorrhoids GWAS preprint is out, almost 1 M people studied! 1st time the genetic architecture of this trait is investigated, we detect 102 loci that point to smooth muscle, epithelial and connective tissue dysfunction with @an_franke and many others medrxiv.org/content/10.110…
👍🏻
Finally, this was a great team effort w/ Alkes Price, @FHormozdiari, @bennerstat, @julirsch, @StevenGazi, @Luke0connor, @MattiPirinen, and many other brilliant people not on Twitter (and requiring >280 chars). Thanks everybody!
@oweissb Yes and wrote a paper about that already in 2017 recommending sharing of LD information doi.org/10.1016/j.ajhg…
Here we go. The PGC Schizophrenia GWAS (phase 3) paper in preprint. A massive group effort and thanks to participants and researchers internationally. Also special mention to SCHEMA colleagues and the papers bear reading alongside each other. medrxiv.org/content/10.110…
@masakanai @andganna @jcbarret @ewanbirney @dvh13 @covid19_hgi @EastLondonGenes @BradfordGenes Assuming a single causal variant. Is the zoomplot not showing a likely second signal? What about getting in-sample LD for HOSTAGE_EUR, UKBB_EUR (which you have already) and GENCOVID_EUR as a start?
@jcbarret @ewanbirney @dvh13 @covid19_hgi @EastLondonGenes @BradfordGenes @andganna Quite a few studies to collect in-sample LD information for proper fine-mapping. However it’s one locus. Any plans/help needed @andganna?
You have a GWAS SNP. Great. Now, what's the causal gene? Really excited to share this preprint with coauthors Vince Forgetta and Lai Jiang, @BrentRichards19 , @markmccarthyoxf , @Greenwood_LDI and others biorxiv.org/content/10.110…
Eric Fauman (he/him) @Eric_Fauman
6K Followers 247 Following GWAS whisperer 'Nothing in biology makes sense except in the light of evolution' DMs open Executive Director, Integrative Biology @Pfizer
Masahiro Kanai @masakanai
1K Followers 520 Following Instructor in Medicine @TheXavierLab | PhD with Mark Daly (@dalygene) & Hilary Finucane | @HarvardMed @BroadInstitute @MassGeneralNews
Zoltán Kutalik @zkutalik
2K Followers 621 Following Statistical Geneticist, Group leader at University of Lausanne/Unisante, father, climber, runner
Alex Strudwick Young @AlexTISYoung
9K Followers 3K Following Asst. Prof. @ UCLA Human Genetics. Statistical geneticist. Advisor @herasight. Oxford PhD. Mendelian inheritance is the most important natural experiment.
Pete Kraft @GENES_PK
4K Followers 334 Following Director, Trans-Divisional Research Program, Division of Cancer Epidemiology and Genetics, NCI, NIH | @peter-kraft.bsky.social | Views are my own.
Jesse Engreitz @jengreitz
4K Followers 415 Following Assistant Professor @stanford Genetics and BASE Initiative. Mapping the regulatory code of the human genome to understand heart development and disease.
John Morris @johnomix
1K Followers 2K Following Assistant Professor at the @UofT @DonnellyCentre and @MoGen_Grad. Large-scale human genetics and massively parallel screens to study disease!
Denis A. Engemann @dngman
2K Followers 2K Following Neuroscientist in Pharma R&D @Roche. Passionate about brains, machine learning, metabolism, health, nutrition ... cycling. Tweets = personal views & opinions.
Fahri Küçükali @maegsul
913 Followers 4K Following Postdoc at @SleegersLab @CMN_VIB working on complex genetics of Alzheimer's. | GWAS, molQTLs, TWAS, splicing, long reads, rare variants. https://t.co/pO7ClZPMdI🦋
Joethemarketer43 @Joseph33743358
284 Followers 2K Following I'm a real estate agent offering real estate services to real estate companies and the customers.
Xinhe Xue @XueXinhe
114 Followers 198 Following Postdoc at Justin Eyquem lab (In vivo cell editing, immunotherapy and functional genomics)
Research Stash @ResearchStash
570 Followers 2K Following Research Stash is a curated collection of tools and news to help STEM researchers excel in their research #ResearchStash #STEM #Tools #OpenResearch 📰 🔬
Lazaros Belbasis @Lazaros_B
170 Followers 1K Following MD, PhD, AFHEA | Research Fellow @Oxford_NDPH (@UniofOxford) | Focusing on brain diseases | Epidemiologist and Physician (he, him, his)
Jeffrey Chiu @JeffreyChiu20
37 Followers 255 Following Interested in microbial evolution and ecology, microbial-host interaction, & health homeostasis.
Arnauld Schwarzenegge... @Schwarzene9mz8
243 Followers 2K Following RÉFLEXIONS......PENSÉES.... ETATS D'ESPRIT....DESIRS....
Melissa Gymrek @mgymrek
2K Followers 299 Following Assistant Professor at UCSD Depts. of Computer Science/Medicine. Interested in genomics, statistics, and programming. Ultrarunning enthusiast.
Linda Ottensmann @LOttensmann
100 Followers 276 Following Joint PhD student @FIMM_UH University of Helsinki and University of Edinburgh @EdinUni_IGC | Interested in Lipidomics, Bioinformatics and Biostatistics
Christian Hammer @christianhammer
261 Followers 227 Following Director Human Genetics at Altos Labs; Past time musician; Opinions are my own.
Jordan Rossen @RossenJordan
115 Followers 231 Following
Alisa Chen @Alisa_QiuliChen
17 Followers 54 Following PHD student | Beijing Institute of Genomics, Chinese Academy of Sciences
Xinyi Jiang @JiangXinyi_
17 Followers 88 Following PhD candidate in Human Genetics @EdinburghUni @EdinUni_IGC | #GWAS #ComputationalBiology #Genomics
Ifeolutembi Fashina @microtemb
110 Followers 137 Following PhD student @genomicsCRT @RCSI_Irl | working on miRNA variation in multiple sclerosis |
Satoshi Koyama @skoyamamd
637 Followers 489 Following Assistant Professor of Medicine @harvardmed Investigator @MassGeneralNews @mghcvrc @broadinstitute
ziten @zitandraw
63 Followers 535 Following
Beiranvand🇮🇷... @drbeiran
962 Followers 4K Following ما شهروند شهر خداییم ما پیرو خرد پیامبرانیم ایرانشهر=سرزمین خدا
Hyeokmoon Kweon 권�... @H_Kweon
238 Followers 1K Following Hermon; Decision scientist at ACMetric; Econ PhD @VUamsterdam @ResearchTI 🇰🇷🇳🇱
Gavin Band @gavinband
79 Followers 80 Following
Arvis Sulovari @arvissulovari
504 Followers 1K Following Genetics and Genomics Ph.D. | MTS @EdisonSci | Previously: Principal Scientist @CajalNeuro | Eichler lab alumn @uwgenome, @uvmvermont, @Dartmouth, @UWCAtlantic
Nathan Skene @n_skene
2K Followers 2K Following Neurogenomics lab @UKDRI at Imperial College. Integrating single-cell data with GWAS to gain insight into brain function and disease
Adewusi Olufemi Adigu... @adigunfemi2021
468 Followers 2K Following I'm a very gentle engineer who cherished and always guide my personality.
Mikael Niku @MikaelNiku
6K Followers 3K Following Lifeform @Earth. PhD, docent, head of department @helsinkiuni Veterinary Biosciences; board @FinnSocImm; early host-microbe interactions. Father, scout, writer.
Andy Oroke PhD @iamAndyOroke
292 Followers 2K Following Dr. Andy Oroke “PhD Environmental Engineering, Innovator, Entrepreneur, leader”
Tamika Tabara @TamikaTabara
22 Followers 310 Following ✊🏽 Aspiring social justice leader. 🧬 Genetics, bioethics, accessibility. She/her. #LGBTQ+ "The time is always right to do what is right." – MLK
Petri Kinnunen @petri_hermanni
194 Followers 835 Following ISI x 2 • AVIOMIES • PJ • DI • Paremman tulevaisuuden rakennuttaja • Intohimoinen pohdiskelija ja palloilija • Pieniä ajatuksia - Suuria tekoja • Kauklahti
Sawar Khan @sawar_khan
113 Followers 2K Following Postdoctoral Researcher at Chinese academy of agricultural sciences, China. Molecular Biologist, Zoologist, Genome Biologist
Wisal Ahmad @QAUWisalAhmad
80 Followers 713 Following Ph.D Scholar at KU Leuven, Belgium Quaidian Once Quaidian Forever #QAU Islamabad Microbiologist 🔬 Zalmi Ex-Comsian
genenetwork @GeneNetwork2
173 Followers 500 Following GeneNetwork is a free FOSS FAIR+ web service for genetics, genomics & EHR data. Precision medicine—Like GTEx but more species, realtime stats. Since Jan 1994!
Chirag Lakhani @cmlakhan
532 Followers 4K Following Currently: Staff Scientist @nygenome in the @david_a_knowles lab. Previously: @HarvardDBMI Postdoctoral Research Fellow in @chiragjp lab https://t.co/APTLHsivM2
Marcus @marcus_NJ
186 Followers 557 Following Senior Data Scientist at Relation Therapeutics | Hanc marginis exiguitās nōn caperet
Hari Somineni @somineniHK
110 Followers 638 Following Statistical Genetics and Data Science @insitro | previously @goldfinchbio | PhD @emorygmb
Anne Antmark @annekarlsson19
665 Followers 4K Following Olen keski-ikäinen nainen joka harrastan askartelua,sisustusta sekä innostun kaikesta uudesta.Harrastan kuntoilua ja lenkkeilyä eri muodossa...😀🏃🚶
Aurora #LicencedBirdR... @Au_Erithacus
5K Followers 4K Following PhD at @uniofglos on #Amazonian Birds. #BTO S Ringer. #Moorhen botherer #NMP. Trap maker. Ringing with kids. Catalan #engagement #Wine #Rioja drinker🍷
Galindo de la Cruz co... @GalindodelaCru2
1K Followers 5K Following
Andrea @AndreavDam
125 Followers 396 Following Clinical biochemist in training, fascinated by adipocytes.
Bioinfhotep @pp0196
1K Followers 2K Following Sequences and consequences. @pp0196.bsky.social @[email protected]
Matti Pirinen @MattiPirinen
128 Followers 24 Following Associate professor of statistical genomics @helsinkiuni, @FIMM_UH.
Omer Weissbrod @oweissb
909 Followers 325 Following If we knew what we were doing it wouldn't be called (data) science
Qingning Wang @Linda_Wang_LEI
105 Followers 205 Following Statistical geneticist @ University of Leicester - cardiovascular diseases & telomere. Swimming enthusiast. Views are my own.
Kumar Veerapen, PhD @mkveerpn
757 Followers 1K Following Geneticist @TakedaPharma | Former postdoc/scientist w @broadinstitute @novartisUS | 🇲🇾 | Hot Yoga & Pilates | Sassy opinions my own | he/him | HinJew
Zoltán Kutalik @zkutalik
2K Followers 621 Following Statistical Geneticist, Group leader at University of Lausanne/Unisante, father, climber, runner
Matti Pirinen @MattiPirinen
128 Followers 24 Following Associate professor of statistical genomics @helsinkiuni, @FIMM_UH.
Taru Tukiainen @ttukiainen
454 Followers 118 Following Human Genomics @ University of Helsinki. PI, Senior Researcher, crazy dog mama, mum to two human beings.
Pyry Helkkula @pyryhelkkula
14 Followers 48 Following
Samuli Ripatti @samrip
1K Followers 761 Following Samuli Ripatti is director of @fimm_uh, director of @coecdg and professor of biometry at @helsinkiuni.Trends for United States
You might like
