Bruno Duarte @bklduarte
Hematologist in Brazil with a primary interest in myeloid malignancies. Opinions are my own. hemocentro.unicamp.br Brazil Joined February 2010-
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You can use this QR code or link bit.ly/47RbHCF to access our recent paper on classification of myeloid neoplasms in @BCD_AACR for free for the duration of @SocietyofHemOnc next week. 🩸 #hemepath #soho2025 #leusm
You can use this QR code or link bit.ly/47RbHCF to access our recent paper on classification of myeloid neoplasms in @BCD_AACR for free for the duration of @SocietyofHemOnc next week. 🩸 #hemepath #soho2025 #leusm https://t.co/np7W94syhk
Excited to share our latest work @Nature! We show that the total number of hematopoietic stem cells (HSCs) in the body is restricted, challenging the classical model that HSC numbers are determined locally by the niche and introducing a new paradigm. (1/9) nature.com/articles/s4158…
Congrats @r_sazevedo on her paper, out today in @BrJHaem She screened CD123 expression in AML to assess CD123 correlation w/ genotype. Timely as more anti-CD123 targeted therapies become available for AML pts #hemepath #LeuSM onlinelibrary.wiley.com/doi/10.1111/bj…
Clonal hematopoiesis (CH) is common in older persons without hematologic disease - but what about those who previously had acute myeloid leukemia, and survived the disease? @ScimonkM looked at CH in 373 AML long-term survivors: onlinelibrary.wiley.com/doi/10.1002/he… (1/10)
📢 Out in @NEJMEvidence 👫N=1132 pts; age 18-60 🔹ND #AML 🔹Consolidation with IDAC vs HIDAC 🔹5-yr OS = 59% vs 58% 🔹Lower incidence of myelosuppressio & AEs with IDAC ➡️ IDAC non inferior to HIDAC #leusm @OncoAlert evidence.nejm.org/doi/pdf/10.105…
The impact of clinical features on survival and relapse of patients diagnosed with T-cell acute lymphoblastic leukemia – a multicenter cohort study - 🇧🇷💚 clinical-lymphoma-myeloma-leukemia.com/article/S2152-…
🎉Excited to present our latest work out today @Nature 1.What gives a leukemia its phenotype – the oncogenic driver or the differentiation stage of the cell-of-origin? 2.Why do RAS mutations always happen late in AML? 3.Who will relapse after VEN? nature.com/articles/s4158…
ASH is redefining ANC reference ranges based on Duffy status. No patient should face uncertainty in their medical treatment because of their genetics. #ASHDEI #HealthEquity
ASH is redefining ANC reference ranges based on Duffy status. No patient should face uncertainty in their medical treatment because of their genetics. #ASHDEI #HealthEquity
CHIP: a novel risk factor for AKI @NatureMedicine. Large 🇨🇦/🇺🇸 collab driven primarily @queensu & @VanderbiltU @AlexBickMDPhD led by incredible @DrFlashHeart. Our part graciously supported by @tmedQueens @QueensPathology @queensuHealth with funding from @PSIFoundation @CIHR_IRSC
CHIP: a novel risk factor for AKI @NatureMedicine. Large 🇨🇦/🇺🇸 collab driven primarily @queensu & @VanderbiltU @AlexBickMDPhD led by incredible @DrFlashHeart. Our part graciously supported by @tmedQueens @QueensPathology @queensuHealth with funding from @PSIFoundation @CIHR_IRSC
Fascinating!
Congratulations to everyone involved! Thank you for your hard work and leadership @wellingtonhemat!
Congratulations to everyone involved! Thank you for your hard work and leadership @wellingtonhemat!
Congratulations to our @CUHematology Division on the @NEJM publication of this fascinating case of fetal induced #GVHD. An incredible case unlike any we have seen. This group did some really elegant work to make this diagnosis. nejm.org/doi/full/10.10…
Great session so far on #GeneTherapy in #hemophilia A at #ISTH2023, chaired by Margaret Ozelo & @paul_batty1 , with major update talks from Johnny Mahlangu, Mark Skinner, @DrSamelsonJones, and more to come !
Congrats Gabi! Very well deserved!
A long time coming, quizartinib improves survival in patients with AML FLT3-ITD not previously treated when combined with standard chemotherapy. A long journey from AC-220 to this. @GACancerCenter authors.elsevier.com/c/1gzz2V-4XL1N…
Fatty liver dz is v common but our understanding of who progresses to inflammation & fibrosis is limited. In @Nature, we discover clonal hematopoiesis as a modifiable risk factor for precision liver dz prevention. nature.com/articles/s4158… @waihaywong @connoremdin B Ebert [1/19]
Out in @Nature today, we describe a new method "PACER" to estimate clonal expansion rate and use it to identify that aberrant TCL1A activation as a cause of #CHIP expansion and potential therapeutic target @J__Stock @Jk_Gopakumar @jaiswalmdphd nature.com/articles/s4158…

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