Ajay Major, MD, MBA @majorajay
Lymphoma faculty @CUHematology. Patient-reported outcomes & quality of life researcher in #lymsm. Founder of https://t.co/kN6qeGGce5 & @inTrainingDoc. 🌈 majorajay.com Denver, CO Joined November 2011-
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Microcapsule review of everything #geriheme at #ASH23 @ASH_hematology Thank you @YoungSIOG @SIOGorg @JGeriOnc for the opportunity to publish this collaboration.
Microcapsule review of everything #geriheme at #ASH23 @ASH_hematology Thank you @YoungSIOG @SIOGorg @JGeriOnc for the opportunity to publish this collaboration.
New signature predicts MBL-to-CLL progression ow.ly/kcqR50RooSl #lymphoidneoplasia
Editing an upcoming special episode of the @ASH_hematology Hematopoiesis podcast for #PrideMonth! 🏳️🌈🏳️⚧️ Stay tuned over at Hematopoiesis, the ASH Trainee Council publication by and for hematology trainees: hematology.org/education/trai…
Thank you to Dr. @MayaAbdallah_MD for the invitation to contribute patient-reported outcomes to this important review piece! #lymsm #mmsm #HRQoL
Great new study by Dr. @guptaarjun90 @JNCI_Now: more days requiring health care interaction = worse survival & patient-reported physical function (in 2° analysis of advanced CRC trial). Further work demonstrating prognostic implications of time toxicity. academic.oup.com/jnci/advance-a…
Will Townsend: Longer FU if glofit in R/R DLBCL: • 40% CMR • DOCR impressive • 18mo PFS if in CR at EOT 66% • CR & DOCR similar in post CAR • use dex as pre-med • MTV predicts response & tox #BSH24
Still catching up on highlights of #ASH2023? Check out some #geriheme highlights here! Shout out to co-authors extraordinaire for their excellent summaries! @ASH_hematology @myCARG @AmerGeriatrics @GeriOncCoP @BUHemeOncFellow @BUgeriatrics
Still catching up on highlights of #ASH2023? Check out some #geriheme highlights here! Shout out to co-authors extraordinaire for their excellent summaries! @ASH_hematology @myCARG @AmerGeriatrics @GeriOncCoP @BUHemeOncFellow @BUgeriatrics
ECHELON-3 press release: OS benefit seen - Randomised P3 in R/R DLBCL - BV+R2 vs R2+placebo - Post-CAR allowed - enrolled 'regardless of CD30 status' Always good to see an OS advantage. BIG question here is the relevance of the control arm. #lymsm pfizer.com/news/press-rel…
Dr. Alison Moskowitz expertly discussed the treatment of R/R HL. Current questions on the field - How to manage pts who received anti-PD1 on 1st line - Do all patients require transplant
Salvage Rx of #HL #AlisonMoskowitz What is optimal Rx after Nivo-AVD? Do all patients need ASCT? From earlier studies: PS-1 blockade app to re-sensitive HL to HDchemo? ⬆️role/resp to ASCT What is role of further PD-1 blockade after Nivo-AVD?? Trials awaited #MSKlymphomaCME
Fantastic talk by @GitaThanaMD 👏 ‘Evaluating adverse events & Rx tolerability in clinical trials’ Impact of AEs on QOL: influence Rx decisions & sequencing. Imp of Patient-reported outcomes. AE: Grade/timing/resolution? Impact on ADLs? Toxicity over time (ToxT) #MSKlymphomaCME
Question for #MedTwitter + hospital admin. What is fair heme/onc/BMT cFTE for a 7-day hospital rotation that has an average census of 20 patients? Wondering what is typical around the country?
Glad to see an interventional study planned addressing ‘chemo-brain’ - cognitive impairment following intensive chemo. Such an important issue for patients. Look forward to seeing the results. #lymsm bmjopen.bmj.com/content/14/4/e…
Vincent Rajkumar @VincentRK
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72 Followers 588 FollowingGracevera Sam-Jolly @gvsj_mdNet
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2K Followers 828 Following | internal medicine | hematology resident ⚕️| • 🇨🇴 📽️🥁🎨📚🏍️ ☕️ 🛸•Gunjan Shah @GunjanLShah
1K Followers 1K FollowingMehndi Dandwani @mehndz
200 Followers 414 Following Doctor by Profession, Dancer by Passion & Writer by Compassion || Palliative Care Fellow @uihealthcare || Boarding Heme-Onc Fellow 2024Agrima Mian @AgrimaMianMD
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518 Followers 173 Following Physician Scientist @danaFarber Cancer InstituteThomas Eliot Lew @thomaseliotlew
304 Followers 181 Following Doc from Melbourne, Australia. Treats patients with blood cancers and researches new therapies. Loves family, immersive theatre and running.Efrat Luttwak @Efrat_Luttwak
54 Followers 120 FollowingCharanpreet Singh @Charanpreet_14
718 Followers 760 Following Clinical Hematologist at PGIMER, Chandigarh. Life-long Arsenal fan. Passionate about Lymphoma and all things lymphoidUrshila Durani @UDuraniMD
63 Followers 57 Following Lymphoma, CAR-T, and BMT @ Mayo Clinic. Interested in #MedEd and improving health care delivery for people with cancer.Satya Prakash Yadav @Satyayadav__
4K Followers 1K Following Director- Pediatric Hematology Oncology & Bone Marrow Transplant, Medanta The Medicity . Chairperson-elect -PHO chapter of IAP @pho_india RT are not endorsementAlberto Lopez-Garcia .. @DrAlbertoLG
1K Followers 558 Following Lymphoma and CLL unit. Clinical trials. @Hospital_FJD 🎓PhD Student @UAM_medicina #Cardioncology 🎋 @ResilienceH2020 #Lymphoma #CLL #CardioOncPaul Bröckelmann @BroeckelmannPJ
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1K Followers 2K Following Viral oncologist and Lymphoma doc | Advocate for people living with HIV @NCIResearchCtr | #HIVonc | She/Her | My tweets are my ownSarah Rutherford @drsarahruth
293 Followers 198 FollowingLia Palomba @LiaPalomba
2K Followers 445 Following oncologist @sloankettering lymphoma expert immunotherapy CAR T cells Waldenstrom’s macroglobulinemiaVivek Patel, MD @vpatelmd
881 Followers 218 Following Assistant Professor @VUMCHemOnc | Co-Host @TheFellowOnCall | Alum of @VUMCMedicineRes @VUMedicine @dukeu | #meded #cancer | Tweets my ownJennifer Crombie, MD @JenCrombieMD
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95 Followers 188 Following Internal Medicine Chief Resident at Northwestern. Lapsed theatre major.Danai Dima @DimaDanai
340 Followers 478 Following Hem/Onc Fellow @ClevelandClinic, #MMsm #CARTsm #BMTsm🏐🏊🏻♀️🏐🇬🇷Michelle Fanale, MD @FanaleMD
423 Followers 1K Following Global Medical Strategy, Lymphoma: Pfizer, previously Seagen. Prior Lymphoma Faculty Physician/ Clinicial Investigator at MD Anderson Cancer Center.Lauren H. Nicholas @lhnicholas
2K Followers 2K Following @[email protected] health economist, surgical outcomes researcher, climber, travelerDr. Valerie Crabtree @drvcrabtree
1K Followers 2K Following wife, mom, pediatric psychologist, sleep and cancer researcher, Psychosocial Chief @stjuderesearch. Tweets my own.Moksha Patel @mokshapatelmd
153 Followers 132 Following Physician, OCD Warrior, informaticist, APP Developer@BijoyTelivala @OncBrothers @CancerNetwrk @OncoAlert @HemOncFellows @RenoHemonc @Innov_Medicine @nihardesai7 @majorajay @DrBonillaOnc @DrMDavids @PallawiTorkaMD @ThanksCancer @jeff_sharman No one should be getting FCR for any genomic subsets of CLL including those with IGHV mutated CLL. We don’t use FCR or any chemo regimen for patients with CLL.
Microcapsule review of everything #geriheme at #ASH23 @ASH_hematology Thank you @YoungSIOG @SIOGorg @JGeriOnc for the opportunity to publish this collaboration.
Perspectives on geriatric oncology research presented at the 2023 American Society of Hematology Annual Meeting: Young International Society of Geriatric Oncology report geriatriconcology.net/article/S1879-… @MayaAbdallah_MD @MazieTsangMD @PallawiTorkaMD @WilliamDale_MD @rochgerionc @myCARG
Great talk @PallawiTorkaMD ‘Challenges in older pts w #lymphoma’ 👏 Defs of ‘older patients’? >60/65/70/75? NOT chronological age to define Under Rx common Fitness assessment? (abbrev) Geriatric assessment: G8 Gait speed TUG sGA Biomarkers of aging? Trials req #MSKlymphomaCME
Dr Crawford - BV+benda in RR Hodgkin • 46 pts • high CMR and ORR rates • high transplant rates • infusion reactions ⬇️ with steroid and antihist prophylaxis Patchy access across 🇬🇧 which is frustrating. #BSH24
How I use genomics and BTK inhibitors in the treatment of Waldenström macroglobulinemia ow.ly/3Vba50Roppr #HowITreat #lymphoidneoplasia
New signature predicts MBL-to-CLL progression ow.ly/kcqR50RooSl #lymphoidneoplasia
Glofitamab Monotherapy phase II #WillTownsend n=154 Fixed duration, all pts admitted 1st dose ☢️Total metabolic tumor volume baseline predicts PFS and ~ risk CRS ❓Useful for future risk stratification & decide drug delivery @BritSocHaem #BSH24
Perspectives on geriatric oncology research presented at the 2023 American Society of Hematology Annual Meeting: Young International Society of Geriatric Oncology report geriatriconcology.net/article/S1879-… @MayaAbdallah_MD @MazieTsangMD @PallawiTorkaMD @WilliamDale_MD @rochgerionc @myCARG
Will Townsend: Longer FU if glofit in R/R DLBCL: • 40% CMR • DOCR impressive • 18mo PFS if in CR at EOT 66% • CR & DOCR similar in post CAR • use dex as pre-med • MTV predicts response & tox #BSH24
Still catching up on highlights of #ASH2023? Check out some #geriheme highlights here! Shout out to co-authors extraordinaire for their excellent summaries! @ASH_hematology @myCARG @AmerGeriatrics @GeriOncCoP @BUHemeOncFellow @BUgeriatrics
Perspectives on geriatric oncology research presented at the 2023 American Society of Hematology Annual Meeting: Young International Society of Geriatric Oncology report geriatriconcology.net/article/S1879-… @MayaAbdallah_MD @MazieTsangMD @PallawiTorkaMD @WilliamDale_MD @rochgerionc @myCARG
Exciting news!! Congratulations to all the investigators but especially 👏👏 to @JeffWardMDPhD and @nancybartlettMD who helped develop this regimen as a Wash U IIT! @WUHemeOncFellow @WashUOnc
ECHELON-3 press release: OS benefit seen - Randomised P3 in R/R DLBCL - BV+R2 vs R2+placebo - Post-CAR allowed - enrolled 'regardless of CD30 status' Always good to see an OS advantage. BIG question here is the relevance of the control arm. #lymsm pfizer.com/news/press-rel…
ECHELON-3 press release: OS benefit seen - Randomised P3 in R/R DLBCL - BV+R2 vs R2+placebo - Post-CAR allowed - enrolled 'regardless of CD30 status' Always good to see an OS advantage. BIG question here is the relevance of the control arm. #lymsm pfizer.com/news/press-rel…
A comprehensive and clear lecture on Recent Advances in CNS Lymphoma by @CwynKate #MSKlymphomaCME - Optimizing induction regimens and HDT-ASCT for consolation if suitable - Emphasizing dose adjustments to avoid toxicity - Exploring novel agents for non-ASCT eligible and R/R pts
Dr. Alison Moskowitz expertly discussed the treatment of R/R HL. Current questions on the field - How to manage pts who received anti-PD1 on 1st line - Do all patients require transplant
Salvage Rx of #HL #AlisonMoskowitz What is optimal Rx after Nivo-AVD? Do all patients need ASCT? From earlier studies: PS-1 blockade app to re-sensitive HL to HDchemo? ⬆️role/resp to ASCT What is role of further PD-1 blockade after Nivo-AVD?? Trials awaited #MSKlymphomaCME
5-year follow-up from the LEGEND-2 study of cilta-cel ⏳ 5-year PFS 21% and OS 49% (despite variable LD). 3 progressions after 5 years. No plateau! 🧠No delayed neurotox 🩸No 2nd heme malignancies 🏋️T cells persisted >1 year for VGPR+ (1 at 5.6 years!) jhoonline.biomedcentral.com/articles/10.11…
Fantastic talk by @GitaThanaMD 👏 ‘Evaluating adverse events & Rx tolerability in clinical trials’ Impact of AEs on QOL: influence Rx decisions & sequencing. Imp of Patient-reported outcomes. AE: Grade/timing/resolution? Impact on ADLs? Toxicity over time (ToxT) #MSKlymphomaCME
Are you still collecting enough stem cells enough for 2 stem cell transplants (~ 3-6 millions cells) ?
Question for #MedTwitter + hospital admin. What is fair heme/onc/BMT cFTE for a 7-day hospital rotation that has an average census of 20 patients? Wondering what is typical around the country?
The Amaya lab turns 2 years this month and I feel so incredibly lucky to work with these talented individuals! They make science so fun! 🎂