Chris Lo 💊🧬🧠 @chrislowh
PhD Candidate @SGDPCentreKCL | Pharmacist @HKUPharm | #genetics #psychiatry #mentalhealth London, England Joined April 2020-
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🚨 My new paper! How can we improve polygenic score (PGS) performance across diverse populations? I benchmarked leading PGS methods across EUR, AFR & EAS ancestries — and found a simple, accurate, and efficient approach. 🔗 tinyurl.com/6cmvxnu2
Millions are spent on parenting interventions. Are they effective at preventing mental health problems? Turns out we can’t be sure…only 2/32 of the reviews in our metareview were of high quality, highlighting the need for robust evidence synthesis. mentalhealth.bmj.com/content/28/1/e…
New study @NatureGenet identifies first genetic risk factor for long COVID. They compared DNA from 16,000 patients vs 1.9 million controls across 24 countries. Here are my key takeaways 👇
Polygenic risk score (PRS) tools are getting better and better! Yue Li & team at McGill report a major update to their PRS software, VIPRS (variational inference of polygenic risk scores) — now lightning fast & ultra-efficient. VIPRS reads ultra-compressed LD matrices (MBs not…
Who benefits from antidepressants? New research from IoPPN (@cathrynlewis, @chrislowh) shows how measuring antidepressant ‘switching can help scientists and clinicians understand why antidepressants work for some people and not for others kcl.ac.uk/news/who-benef…
Next up at our Data Science Meeting, @chrislowh from @KingsCollegeLon introduces T-Rx: an R package that simplifies the processing of prescription records into exposure periods and treatment-related #phenotypes. This toolbox makes it easy to work reproducibly across databases,…
Three quarters of people who have taken #antidepressants say they helped them "feel better" in new IoPPN research. Read more➡️kcl.ac.uk/news/three-qua… #SSRI @wellcometrust @EdinburghUni @NIHRMaudsleyBRC
🚨So delighted to see this work looking at the genetic overlap between depression symptoms and Alzheimer’s disease now published in @NatMentHealth @SpringerNature🚨 Read the paper here: 👉 nature.com/articles/s4422…
🚨So delighted to see this work looking at the genetic overlap between depression symptoms and Alzheimer’s disease now published in @NatMentHealth @SpringerNature🚨 Read the paper here: 👉 nature.com/articles/s4422…
Excited to be completing my first book “How psychedelics work” early in the new year. 12/13 chapters written. As I say in the intro, it could just as easily have been titled differently, like these:
Merry Christmas everyone 🎅🏻 Thank you for the messages today ❤️ WOW it’s been an emotional one 🥹 Tune in to @BBCBreakfast tomorrow morning 8.15am to watch us live and hear all about our day with the reds 😬🔴⚽️ YNWA!!
The 2023 ACC/AHA #AFib guideline recognizes AFib as a disease continuum that starts with patients at-risk but without diagnosed AFib (Stage 1) and progresses to those in a permanent state of AFib (Stage 4). Learn more from the AFib Guideline Hub: bit.ly/3Nge8Uo…
Our new paper is a pharmaco-epi study on associations of montelukast with neuropsychiatric conditions in children and adolescents
Our new paper is a pharmaco-epi study on associations of montelukast with neuropsychiatric conditions in children and adolescents https://t.co/R1SvBUoeS9
@chrislowh @uk_biobank @genscot @MatthewIveson @VangelisVassos @WrayNaomi @mcintosh2001 @alex_c_gillett @michelleukamp @ChiaraFabbri12 @heathersibley99 @SGDPCentreKCL @medrxivpreprint Switching patterns 👉Median time to switch: 28 days 👉 Switching to SSRI (50%), TCA (33%) or other drugs 👉More recent prescriptions had ⬆️switching %, ⬇️ shorter time to switch 📷4/7 - our favourite figure
Here’s my turn for a preprint :) Medrxiv link: medrxiv.org/content/10.110…
Here’s my turn for a preprint :) Medrxiv link: medrxiv.org/content/10.110…
interesting work by @lgilchrist1 on MR between metabolites and psychiatric disorders!
interesting work by @lgilchrist1 on MR between metabolites and psychiatric disorders!
🚨New preprint alert 🚨 from AMBER group @cathrynlewis Shoutout to @michelleukamp ‘s work on ‘self-reported #antidepressant response’ data using @uk_biobank mental health questionnaire data! Characteristics resembles known evidence of SSRI response in clinical trials.
🚨New preprint alert 🚨 from AMBER group @cathrynlewis Shoutout to @michelleukamp ‘s work on ‘self-reported #antidepressant response’ data using @uk_biobank mental health questionnaire data! Characteristics resembles known evidence of SSRI response in clinical trials.
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ShareholderYield🇺�... @Ceeloo1479
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Institute of Psychiat... @KingsIoPPN
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Matúš Falis @matt_falis
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Yen-Feng Lin @YenFengLin
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Acta Neuropsychiatric... @scnpjournal
191 Followers 552 Following Acta Neuropsychiatrica is an international journal focusing on translational neuropsychiatry. We publish high-quality original research papers and reviews.
Lifecourse Epidemiolo... @life_epi_psych
95 Followers 102 Following • Research group @EdinburghUni • Examining longitudinal patterns of mental health, their causes & consequences 📈 • Big fans of population data
Dr Ruby Tsang 🇦�... @rubietsang
453 Followers 1K Following Senior Research Associate @ Bristol | Life course epi, multimorbidity, mental health, dementia, biomarkers, cohort & EHR research | Prev @ Oxford/UNSW/Sydney
Nóra Eszlári @NEszlari
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Heather Marriott @HevMarriott
295 Followers 441 Following Postdoc in Translational Bioinformatics of ALS/MND @kingsmnd @neuroshef 🧠 | @mndassoc and @MNDScotland Pre-Fellow | All views are my own. she/they 🌈
Cecelia @6I2TlL2KwXIcd2
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Alex Kwong @asfkwong
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197 Followers 307 Following Postdoc at SMARTbiomed, Bjarni's @bvilhjal group at NCRR, Aarhus University.
Luna Wei Yue @WeiYLuna
73 Followers 67 Following Post-doctoral Fellow @HKU_D24H |Department of Pharmacology and Pharmacy, HKU @HkuPharm | Pharmacoepidemiology, real-world study, electronic health data
Morgan James Morgan @morganjmorgan
72 Followers 64 Following Autistic PhD student - University of Surrey - Autism (Genetics, Individual Differences, Support)
Dr. Margherita Malanc... @MarghMalanchini
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Quan Zhou @QuanZhouu
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Salvesen Mindroom Res... @SMRCResearch
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Megan @megansresearch
95 Followers 218 Following psychedelics & mental health researcher @Hystelica @EdinUniMentalH @EdinUniBrainSci @WeHeroicHearts @Scot_PsychRes @DRNScot
Luna @echo173624
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Tim Kerr @InTheDocBlog
61 Followers 117 Following Former doctor. Former prisoner. Those two facts are related. Current PhD student (Psychiatry).
Luna @MingleMist87035
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Madhur Bain Singh @Madhur_B_Singh
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640K Followers 396 Following Free Stock Market News that is FAST, ACCURATE, CONSISTENT, and RELIABLE | Not Just Stock News | My Daily Stock Market Recap is the link in my bio ⬇️
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553 Followers 888 Following StatisticalGenetics @depgenafrica @SGDPCentreKCL Philippians 4:13 #MUFC #LOSC_Lille 🇰🇪
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DeSci Foundation @DesciFoundation
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DeSci Labs @DeSciLabs
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The Football Era @FootballEra_
7K Followers 99 Following “Present and Future of the game lies in Player Profiling...” • Football Writer, Analyst & Educator • Licensed Pro Scout • Enquiries ➠ [email protected]
nature @Nature
2.6M Followers 3K Following Research, News, and Commentary from Nature, the international science journal For daily science news, get Nature Briefing: https://t.co/wGmQlQ8a4D
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King's CRSD @KclCRSD
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National Institute fo... @NIHRresearch
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Footie's HAWK-EYE �... @ManuelWiliam504
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UKRI Mental Health Pl... @MHPlatform
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18K Followers 953 Following @Arsenal, Lots of typos, Random Football Stats, Nostalgia Merchant 🇧🇩🏴 #FreePalestine🇵🇸. Dolphins1925
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198 Followers 203 Following Postdoc in Division of Psychiatry, University of Edinburgh. Neuroscience. Genetics.
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3K Followers 1K Following Make a difference to health research in under 20mins. Open to anyone in Scotland aged 12+ 🧬
UK Biobank @uk_biobank
20K Followers 1K Following A large-scale biomedical database and research resource, that can be accessed globally by approved researchers, to enable scientific discoveries.
Chiara Fabbri @ChiaraFabbri12
304 Followers 180 Following associate professor at University of Bologna #pharmacogenetics #depression Past: @Fondaz_Veronesi fellow, Marie Sklodowska Curie fellow at @SGDPCentreKCL
medRxiv @medrxivpreprint
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