Fodor Laboratory @fodorlab
We're a molecular and structural virology lab working mainly on influenza @Dunn_School, @UniofOxford fodor.path.ox.ac.uk Oxford, England Joined November 2020-
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Ed Hutchinson discusses bird flu in cattle on @guardianscience
Ed Hutchinson discusses bird flu in cattle on @guardianscience
Happy to have contributed to this work. Tremendous structural work by Benoit. This work makes a lot pretty clear when it comes to host-adaptation. Very complementary and consistent to this pre-print from the Fodor and Grimes groups: researchsquare.com/article/rs-371…
Another great paper from the Cusack and Naffakh labs on influenza virus genome replication and host adaptation.
Another great paper from the Cusack and Naffakh labs on influenza virus genome replication and host adaptation.
Excited to share our work offering insights into how adaptive mutations enable avian influenza viruses to replicate their genome in mammalian cells @jonathan_grimes @wendybarclay11 researchsquare.com/article/rs-371…
Huge congratulations to Dr @FangzhengWang for passing his viva! Thank you @AlexBoRNA and Nick Proudfoot for being the examiners! So…how many transfections was the DPhil worth?
Great to be back on the same stage @MicrobioSoc sharing the lab’s recent discoveries on our favourite influenza virus RNA polymerase! #microbio24
Very happy that @alaa_baazaoui's first first-authored paper is out. Using cryoEM we describe the Pol-II CTD binding site and observe a new arrangement of the flupol PB2. The structural work is nicely complemented by functional work. doi.org/10.1128/jvi.00…
Congratulations to @AlexBoRNA! A much deserved award!
Congratulations to @AlexBoRNA! A much deserved award!
Im looking to recruit a Postdoc to work on anti-viral drug discovery against Flu. Funded by the PAD initiative (padinitiative.com) Great people, great lab, and a great boss 😎 my.corehr.com/pls/uoxrecruit…
1/n Very excited to share my lab's latest manuscript, nearly 3 years after I started my independent group! This was a fantastic collaboration with Bryan Johnson and @TheMenacheryLab, led by joint 1st authors @hannah_kubinski and Hannah Despres in my lab biorxiv.org/content/10.110…
@Dunn_School's @fodorlab wins the Sustainable Lab Award. Well done to this group for trying to significantly reduce your lab's environmental footprint. Thanks to the Roberts, Proudfoot and @JRafflab labs for organising the Dunn Drinks and ceremony. Lots of T-shirt prizes to give!
It’s amazing what you can find in 106 yr-old autopsy samples—two, complete 1918 H1N1 genomes! Congrats to the authors and thank you for letting me contribute a small part to this fascinating study 🦠🫁 #flu #virology journals.asm.org/doi/10.1128/mb…
SARS-CoV-2 biology and host interactions @NatureRevMicro An updated summary of the SARS-CoV-2 life cycle, gene function and virus–host interactions, including recent landmark findings on coronavirus biology trebuchet.public.springernature.app/get_content/d4…
Transient RNA structures contribute to highly pathogenic flu emergence! Fantastic work by Mathis Funk and Mathilde Richard now on BioRxiv: biorxiv.org/content/10.110… For supporting data see: science.org/doi/10.1126/sc…
Big thanks to @PLOSBiology for highlighting our work as your annual favourite! 💕 Genuinely flattered 😍 I do hope it makes a fun Christmas reading journals.plos.org/plosbiology/ar… Check out here for the PLOS Biology 2023 editor’s summary of interesting articles: journals.plos.org/plosbiology/ar…
"Among our microbiology content, one of our favorites was “Defining the minimal components of the influenza A virus replication machinery via an in vitro reconstitution system” from the Fodor lab [6] for its apparent simplicity and elegance."
"Among our microbiology content, one of our favorites was “Defining the minimal components of the influenza A virus replication machinery via an in vitro reconstitution system” from the Fodor lab [6] for its apparent simplicity and elegance."
Had a great time presenting at the 2023 Influenza Update Meeting to end the term and begin the holiday season! And big congrats to fellow Fodorian, @RepAlison, for winning best talk at the meeting! 🦠🧬🔬 Now, time to listen to Christmas music on blast 🎶🎄
Big thanks to @StephLeeann95 and @RepAlison, for delivering two great talks on behalf of the lab at this year’s Influenza Update Meeting! And congratulations to Alison for winning the best talk prize!
📢#hiring #postdoc📢 There are two postdoc positions available in my lab at Zhejiang University @ZJU_China, China🇨🇳. There will be full of🦠🔬🍻 taken place. Please DM me for more information.
The Cusack group shares in a @Nature paper cryo-EM structures of the Tilapia Lake virus's RNA polymerase, a fish pathogen. It shows similar domains and functionality to the distantly related influenza virus' polymerase, despite being only 60% the size. nature.com/articles/s4146…
Dunn_School (and @Dun.. @Dunn_School
4K Followers 404 Following Sir William Dunn School of Pathology, University of Oxford. We research the biology underlying disease. Increasingly to be found @DunnSchool.bsky.social You
Hutchinson Lab @CVRHutchinson
8K Followers 6K Following Molecular virology lab @CVRinfo @UofGlasgow @The_MRC | Social media influenza | Group account | Posts often, but not always, from Ed Hutchinson (he/his)
Matthew Freeman @mjafreeman
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Elly.Gaunt_lab 💙 @GauntLab
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Ed Emmott @edemmott
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Stephen Graham's Lab @AtomicVirology
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Dunn_School (and @Dun.. @Dunn_School
4K Followers 404 Following Sir William Dunn School of Pathology, University of Oxford. We research the biology underlying disease. Increasingly to be found @DunnSchool.bsky.social You
Hutchinson Lab @CVRHutchinson
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MRC-Uni of Glasgow Ce.. @CVRinfo
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MRC Laboratory of Mol.. @MRC_LMB
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Science Magazine @ScienceMagazine
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701 Followers 1K Following The XVIth International Nidovirus Symposium 14. - 18.05.2023, Montreux, Switzerland
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Stephanie L. Williams @StephLeeann95
112 Followers 125 Following Virologist | Emerging and re-emerging RNA viruses | Influenza A | NIH-Oxford University Scholar | DPhil Candidate Taubenberger & @Fodorlab | Views are my own.
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Diego Cantoni @DiegoCantoni92
609 Followers 951 Following Virologist - How do viruses get in?! PDRA at MRC-University of Glasgow Centre for Virus Research @CVRinfoMost importantly this work is also consistent with the model we recently proposed that the replication complex is tethered to the host RNA polymerase II CTD domain through the CTD binding sites of the replicating viral polymerase: nature.com/articles/s4146…
How does the flu polymerase replicate RNA and adapt to hosts? Read our pre-print: Structures of influenza A and B replication complexes explain avian to human host adaption and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase biorxiv.org/content/10.110…
There is much more to discover in the pre-print, e.g. FluPol trimers with further implications for genome replication and the fact that ANP32 seems to chaperone the flu polymerase (like described before for other targets).
The FluC polymerase-ANP32 replication complex was known. However, on the amino acid level there are many differences to FluA/B. That's why it was so important to have the complex available in order to improve our understanding of host adaptation (e.g. cattle outbreak in NA).
How does the flu polymerase replicate RNA and adapt to hosts? Read our pre-print: Structures of influenza A and B replication complexes explain avian to human host adaption and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase biorxiv.org/content/10.110…
Very cool work showing avian H5N1 FluPolA in complex with human ANP32B!
Excited to share our work offering insights into how adaptive mutations enable avian influenza viruses to replicate their genome in mammalian cells @jonathan_grimes @wendybarclay11 researchsquare.com/article/rs-371…
Super happy to see this in @NatureComms! A huge thanks to the coauthors and the entire @TBharat_lab, particularly @buse_isbilir, who really help get the project over the finish line
Cell cycle dependent coordination of surface layer biogenesis in Caulobacter crescentus. Finally in peer reviewed form with even more data. Congrats @matt_herdman @buse_isbilir and team! rdcu.be/dE8nW
Cell cycle dependent coordination of surface layer biogenesis in Caulobacter crescentus. Finally in peer reviewed form with even more data. Congrats @matt_herdman @buse_isbilir and team! rdcu.be/dE8nW
Congratulations Ivan and Omer! 👏👏👏 The @IvanAhelLab and @Dushek labs have been awarded prestigious @wellcometrust Discovery Awards programme grants! Find out more: path.ox.ac.uk/news-article/t…
Very humbled to receive this long-term funding! Thank you to past and present lab members, collaborators, and funders for making this possible!
Congratulations Ivan and Omer! 👏👏👏 The @IvanAhelLab and @Dushek labs have been awarded prestigious @wellcometrust Discovery Awards programme grants! Find out more: path.ox.ac.uk/news-article/t…
We are excited to share our latest #preprint Wachsmuth-Melm et al on cryo-ET of influenza infection in colaboration with @mjamorim1 team on @researchsquare: Influenza A virus hemagglutinin remodels membranes into a vRNP clustering platform researchsquare.com/article/rs-400…
Great to be back on the same stage @MicrobioSoc sharing the lab’s recent discoveries on our favourite influenza virus RNA polymerase! #microbio24
Huge congratulations to Dr @FangzhengWang for passing his viva! Thank you @AlexBoRNA and Nick Proudfoot for being the examiners! So…how many transfections was the DPhil worth?
@BiochemSoc Delighted and honoured to receive this Award! This wouldn’t have been possible without many wonderful people who mentored and supported me, from Leeds, to Munich, Oxford, and Cambridge. It is also a celebration of our research, and of many talented people contributing to it!
Congratulations to Dr Alex Borodavka who receives The Colworth Medal in 2025! @AlexBoRNA's outstanding research incorporates an imaginative combination of state-of-the-art interdisciplinary approaches to understand the molecular virology of multi-segmented RNA viruses.
This is one for us and looks great! Perhaps I don't have to worry about being wrong now (famous last words).
Nature research paper: Structural basis of exoribonuclease-mediated mRNA transcription termination go.nature.com/3TTQ4KC
Big news! Influenza immunity and vaccine development expert @florian_krammer has started a professorship of Infection Medicine at the University of Vienna! His Vienna group’s focus will emphasize viruses with pandemic potential. Read more here: ow.ly/k1S850R030a
Our latest study, now out in @JMedVirol, delves into enzalutamide's potential as an antiviral against human coronaviruses, revealing insights into viral-Androgen Receptor signalling. @NJTemperton @wendybarclay11 @BevanLab @GregBrooke4 onlinelibrary.wiley.com/doi/full/10.10…
Thoroughly enjoyed getting the opportunity to speak at the 35th UK RNAP meeting! Such a friendly group and lots of great feedback. Huge thank you to @AchillesKap's group for organising @Hafezelsayyed, @jagadishhazra and @ojp25 🔬🧪
1/n Very excited to share my lab's latest manuscript, nearly 3 years after I started my independent group! This was a fantastic collaboration with Bryan Johnson and @TheMenacheryLab, led by joint 1st authors @hannah_kubinski and Hannah Despres in my lab biorxiv.org/content/10.110…
Kacper (@ExeterCollegeOx this week) is a tough act to follow. Good luck to whoever is speaking this weekend!! exeter.ox.ac.uk/events/sir-pau…
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