#NewPI in #RNA #Virology, electron microscopy aficionado, gardener, parent, Assistant Professor @UVMLarnerMed. Prev @Gates_Cambridge scholarJoined January 2016
My concern at the moment is that H5N1 might evolve at a different rate in cattle than in birds. And until we have the sampling dates for the cattle viruses, we won't know if it is faster or slower (or the same) in cattle and birds.
Reading this story that some of the at-market #H5N1 milkbtesting is Andy Bowman and Rich Webby making broad grocery trip runs centered out of Columbus (OH) and Memphis is on target for those two.
Reading this story that some of the at-market #H5N1 milkbtesting is Andy Bowman and Rich Webby making broad grocery trip runs centered out of Columbus (OH) and Memphis is on target for those two.
Reminder:
If you would like to analyze bovine H5N1 influenza A virus consensus sequences from SRA data shared by @USDA_APHIS , @xrayfoo has assembled them and we have shared them here.
Please repost (if willing).
github.com/andersen-lab/a…
1. So much today on the #H5N1#birdflu story! Just coming up for air. @US_FDA has found genetic evidence of the virus in commercial milk, but so far it sounds like killed virus. More info on where they found it/how prevalent it was would be useful. statnews.com/2024/04/23/h5n…
So, *preliminary* molecular clock analyses indicate that the time of the most recent common ancestor (TMRCA) of the US cattle flu clade was late December.
TMRCA of that clade and the closest relatives in birds, mid-December.
If single intro, likely between those rough dates.
It’s fantastic @NIAIDNews is focusing on ESIs who work on HIV. Are there similar plans to support ESIs working on other viruses at risk of causing global pandemics like influenza and coronaviruses?
It’s fantastic @NIAIDNews is focusing on ESIs who work on HIV. Are there similar plans to support ESIs working on other viruses at risk of causing global pandemics like influenza and coronaviruses?
OK, I think we're close to decisive evidence that US bovine H5N1 had a single origin from birds, and that when related viruses from birds *have* been found, they are jumps from cattle back into birds.
Grackles, blackbirds, chickens all show mammalian adaptation like PB2 M631L.
Here is a link to 239 consensus genome sequences, assembled by @xrayfoo, from sequencing reads of 2.3.4.4b H5N1 influenza A virus from cattle and other species.
github.com/andersen-lab/a…
Lots of fair questions in this article. I do not envy the heavy task of the USDA and supporting labs and researchers, but there has to be more information sharing to the best of their ability. #influenza#H5N1statnews.com/2024/04/18/h5n…
The testing approach to H5N1 in cattle (in the link) needs to change substantially. @USDA_APHIS may be doing what it can now with minimal resources, but testing needs to expand, get simpler, more available and transparent.
aphis.usda.gov/sites/default/… 1/x
There should be a GI bill and VA benefits and every other benefit we give military workers for every health care provider who worked from 2020 until we had a Covid vaccine.
Because H5N1 is not a reportable disease in cows, it's likely we are underestimating this outbreak. Additionally, the majority of workers on dairy farms (especially large farms) are undocumented & are less likely to report symptoms. I worry we are underestimating human infections
Because H5N1 is not a reportable disease in cows, it's likely we are underestimating this outbreak. Additionally, the majority of workers on dairy farms (especially large farms) are undocumented & are less likely to report symptoms. I worry we are underestimating human infections
The Ganti Lab will be opening this August @stonybrooku. We are interested in uncovering the mechanisms governing cell-cell viral spread and how prior immunity shapes avian influenza dynamics. Hiring at all levels. Email: [email protected]
I am thrilled to have this research support to take the lab in new directions! Also, new funding means we are looking for a talented postdoc to join our team. Please share widely and apply today. jobs.sciencecareers.org/job/656769/pos…
I am thrilled to have this research support to take the lab in new directions! Also, new funding means we are looking for a talented postdoc to join our team. Please share widely and apply today. jobs.sciencecareers.org/job/656769/pos…
⚠ Increased avalanche risk ⚠
Today's heavy snow combined with antecedent snowpack conditions has led to greater risk for avalanches in the back country of the Green Mtns & Adirondacks. Similar conditions caused this avalanche on Whiteface Mtn in March 2011, shown in the photo.
Spread the word about the CVSD budget vote! Do your friends and neighbors know about it? Check out the Budget Overview resource, the FAQs resource, and more on the budget page of the district's website. cvsdvt.org/budget@cvsdvtsupt#cvsdvt
In response to the H5N1 infections in cows and now a human in Texas, we've just updated our North America specific H5Nx Nextstrain build with the cow and goat sequences, which are viewable under "Species-grouped: Ruminant": nextstrain.org/groups/moncla-…. A few notes.
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V5=3xancestral+1x bivalent+1xXBB
Professor at the Department of Microbiology
Icahn School of Medicine at Mount Sinai
8K Followers 6K FollowingMolecular virology lab @CVRinfo @UofGlasgow @The_MRC | Social media influenza | Group account | Posts often, but not always, from Ed Hutchinson (he/his)
9K Followers 2K FollowingVirologist | Principal Scientist | Adjunct Professor | Co-Lead, One Health @USask. My team investigates highly pathogenic zoonotic viruses #LZCI | My views
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