Chris Brooke @_chris_brooke
Viral evolution, infection dynamics, etc. Associate Professor at the University of Illinois. brookelab.org Champaign, IL Joined January 2016-
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We have an open faculty search for TWO positions in microbiology and virology at the University of Illinois! We have world class core facilities and a fantastic collaborative group of young faculty...you could be next! Please RT!
Check out @Joel_RiveraC 's new preprint examining how the seasonal H1N1 and H3N2 lineages of IAV differ in their ability to antagonize IFN induction and signaling, and how these phenotypes have evolved over decades of circulation in humans: biorxiv.org/content/10.110…
Check out @TripleAHelix1 's new paper on how the evolutionary potential of seasonal H1N1 HA is influenced by its interactions with the neuraminidase in @Virus_Evolution! academic.oup.com/ve/article/10/…
My work w/ @KoelleLab & Nick Berg on the within- and between-host dynamics of influenza defective viral genomes during humans infections is out in @Virus_Evolution! Thanks to the reviewers for helpful feedback and VE for being a great journal to work with doi.org/10.1093/ve/vea…
Extremely excited to see our paper out in @Nature! How does the body respond to SARS-CoV-2, and what happens if you don't get infected after exposure? We unravel the exact timeline of the cellular responses to inoculation with SARS-CoV-2 in humans. (1/4) nature.com/articles/s4158…
As diagnostic testing options expand, so do questions of how to most effectively use them. ⚖️ More sensitive vs less? 🤧 Screening vs symptom-based? ⏳ Test immediately vs wait? We developed a model to estimate the costs and benefits of these tradeoffs. science.org/doi/10.1126/sc…
Have you ever wondered why there are so many subtypes of immune cells? In our work published today at @Nature, we offer one possible reason – the capacity to evolve. 1/n nature.com/articles/s4158…
Few more days to submit your abstract ! @SBRoscoff @Rafa_Sanjuan_ @MT_Sofonea @Mark_P_Zwart @PaulTurnerLab @willemsen_anouk @bkoskella @DirtySci @anice_lowen @katrina_lythgoe @samuel_alizon @Stefandkex @sociovirology @Lucie_Virevolte @pilardomingoc @SantiagoFElena @_chris_brooke
Deadline approaching, get those applications in!! #lovevirology
Deadline approaching, get those applications in!! #lovevirology
We have an open virology faculty search at the University of Illinois! We have world class core facilities and a fantastic collaborative group of young faculty working on cutting edge questions in virus biology...you could be next! Please RT!
T cell responses matter during "breakthrough" SARS-CoV-2 infection. Here's new work from @markmpainter Really supports the notion that we should be trying to measure T cells as a correlate of protective immunity for SARS-CoV-2 (and maybe other) vaccines. nature.com/articles/s4159…
🧵(1/6) How do immune cells know where to go? It has been proposed that cells simply respond to externally established gradients of chemokines, but we think that’s not all…
Transcriptional regulation by pathogen-programmed Cas9 (TRPPC) where influenza viruses encoding sgRNAs alter host gene expression to affect their own fitness highlights how DNA sensing amplifies innate immune responses tempered by TREX1 @MehleLab cell.com/cell-host-micr…
You need a cheat sheet to effectively get from microscope image to publication-ready figure? You may like the poster summaries @ChriSchmied and I made. Fun fact, we used as template of the great @posit_pbc @rstudiotips cheat sheets 😁 blog 7: helenajamborwrites.netlify.app/posts/image_ch…
Come be my colleague! The Department of Immunology and Microbiology at the University of Colorado Anschutz Medical Campus is hiring a tenure-track Assistant Professor working at the intersection of infection and host immunity. cu.taleo.net/careersection/…
Big news. My lab's first viral hepatitis paper is out in @HEP_Journal! A new model for chronic #HCV. Collabs with old friends @ScheelLab @RiceLaboratory #collaborativecross journals.lww.com/hep/Abstract/9…
REVIEW @NatureRevMicro: Co-evolution of immunity and seasonal influenza viruses @colinrussell nature.com/articles/s4157…

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Bryan C Mounce @bryancmounce
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