Chris Jenkins @gchrisjenkins
@UVAEngineers Joined December 2018-
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Big Starship milestone at KSC as the first section of the flame bucket is being lifted into the 39A trench. nsf.live/spacecoast
For over a century, antibiotics were found by slow, painstaking, serendipitous screening. Today we share a different path: the first demonstration of deep reinforcement learning (RL) for antibiotic discovery. I’m thrilled to introduce ApexAmphion—inspired by the systems that…
Given recent events, I think now might be a good time for someone to launch a dark pool perp DEX. I have always been puzzled with the fact that everyone can see your orders in real-time on a DEX. The problem is worse on a perp DEX where there are liquidations. Even with a CEX…
We sought to make proteins both potent and FAST. We used #proteindesign to design precise control over protein interaction lifetimes, enabling us to construct rapid-response circuits, biosensors, and switchable cytokines. Now published @Nature! Links to paper and tutorial below.
Today, we report Germinal, a method for efficient de novo antibody design, with @santimillef and @SynBioGaoLab. Germinal achieves success rates of 4-22% across diverse epitopes. We make the work fully open, without doing lame things like posting a preprint without methods. 🧵
The ability to design antibodies against any protein of interest has major implications for medicine, biotech, and basic science. Today, we introduce Germinal, a pipeline for epitope-targeted de novo antibody design achieving 4–22% success rates with efficient experimental…
Postdoc position available in the BioEmu team at @MSFTResearch AI for Science - Berlin DE or Cambridge UK. Looking for candidates with backgrounds in #MachineLearning #AI Biophysics or Bioinformatics jobs.careers.microsoft.com/global/en/job/…
Postdoc position available in the BioEmu team at @MSFTResearch AI for Science - Berlin DE or Cambridge UK. Looking for candidates with backgrounds in #MachineLearning #AI Biophysics or Bioinformatics jobs.careers.microsoft.com/global/en/job/…
The directional derivative of a scalar field ℒ:ℝᴺ → ℝ at w⁰ along direction û is given by: Dᵤℒ(w⁰) = ∇ℒ(w⁰)ᵀ û = ‖∇ℒ(w⁰)‖ cos ϕ, where ϕ is the angle between ∇ℒ(w⁰) and û. The direction of maximum decrease has û pointing towards −∇ℒ(w⁰).
Our CEO is live now on @Cointelegraph AMA! x.com/i/broadcasts/1…
Jasmine and Ilhan spew hate every time they open their mouth and it is total bullsh!t. They are the problem, certainly aren’t the solution, and they both need to go.
Jasmine and Ilhan spew hate every time they open their mouth and it is total bullsh!t. They are the problem, certainly aren’t the solution, and they both need to go.
Universal machine learning forcefields beating tailor made classical potentials for zeolites quite convincingly. Great to see all these benchmarking papers! Again demonstrates accurate training data + speed should be key focus now. arxiv.org/abs/2509.07417
finally, our 3rd and last case study, and it's the one I consider the most complex and most interesting: a target and which patients stand to benefit the most from that target being modulated discovered entirely via the virtual-cell model at @NOETIK_ai noetik.blog/p/how-do-you-u…
So I think I've found another pretty incredible example of the generalisability of neural network potentials: this is a problem I've been dreaming of tackling for a decade but never felt I had the the tools to get at until now: How do potassium ion channels work. 1/n These…
So I think I've found another pretty incredible example of the generalisability of neural network potentials: this is a problem I've been dreaming of tackling for a decade but never felt I had the the tools to get at until now: How do potassium ion channels work. 1/n These… https://t.co/3UT8EqD75N
This is also one of the only applications in deep learning other than our work on FermiNet/QMC where using second order optimizers like KFAC really is the difference between working and not working. You need very high numerical accuracy and can sample arbitrary numbers of inputs.
This is also one of the only applications in deep learning other than our work on FermiNet/QMC where using second order optimizers like KFAC really is the difference between working and not working. You need very high numerical accuracy and can sample arbitrary numbers of inputs.
BioEmu now published in @ScienceMagazine !! What is BioEmu? Check out this video: youtu.be/LStKhWcL0VE?si…
BioEmu now published in @ScienceMagazine !! What is BioEmu? Check out this video: youtu.be/LStKhWcL0VE?si…
A cheekier version
i've lived in the united states for most of the 42 years i've been alive, and i've never had people be openly racist to me. until i heard from all the people either openly on X or privately in DMs hurling racist abuse at me for switching to the republican party. eye opening.
Scientists Reversed Aging in Monkeys. Humans Could Be Next Scientists demonstrated that senescence resistant mesenchymal progenitor cells (SRCs), engineered with the longevity gene FOXO3, can not only halt aging but partially reverse it in aged macaques. 👀 Intravenous SRC…
The White House just posted an emotional and extremely powerful video honoring Charlie Kirk: "It's bigger than you, remember that... It's bigger than me. You’re here to make somebody’s life better, the pursuit of liberty & freedom."
When we at @OpenAI released o1-preview a year ago, it would think for seconds. Today, our best reasoning models can think for hours, browse the web, and write code. But there's a lot of room to push reasoning even further. I'm excited for what the next year will bring!
When we at @OpenAI released o1-preview a year ago, it would think for seconds. Today, our best reasoning models can think for hours, browse the web, and write code. But there's a lot of room to push reasoning even further. I'm excited for what the next year will bring!

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Molecular Machine Lea... @molecularML
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Fanwang Meng @FanwangMeng
592 Followers 4K Following Banting Postdoc Fellow at Heidar-Zadeh Group at Queen's University|Postdoc at Coley Group at MIT | Ph.D. at Ayers Group at McMaster Univ.; ML for drug discovery
Guido von Rudorff @ferchault
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Orozco Lab @orozco_lab
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Alex Combessie @alex_combessie
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Alexander Imani Cowen... @ImanisMind
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Thibault Lapierre @ThibaultLapier4
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the Piquemal Group @PiquemalGroup
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Laboratoire de Chimie... @LCT_UMR7616
3K Followers 2K Following LCT is a joint @Sorbonne_Univ_ & @CNRS Research Center. #compchem. ⚠ Frozen account 👉 Follow us on #BlueSky: https://t.co/Z9V8Fz0Bh5
Vojtech Spiwok 🇺�... @spiwokv
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Aleksey Kuznetsov @aleksey73kuzne1
2K Followers 2K Following #compchem Comp. chemistry group leader, assistant professor. Studies of novel core-modified porphyrins, Ru-complexes, MOFs, organic compounds for medicine.
Artur Góra @_artgora
2K Followers 3K Following Computational Chemist | Head of the Tunneling Group at Biotechnology Centre SUT | water & solvents as molecular probes
Giulia De Rosi @giulia_derosi
553 Followers 2K Following Assistant Prof. @ETSABarcelona & #Quantum Theoretical #Physicist on #UltracoldAtoms in the BQMC group @la_UPC | #WomenInScience | #SciComm | 🤺 🥉🎤 🎸🛹 🏐 🚲
TINKERtools @TINKERtoolsMD
3K Followers 2K Following The Tinker Molecular Modeling Package: Tinker & Tinker-HP. Developer-Friendly | Free | Polarizable FFs & ML #HPC Tweets: @jppiquem @prenbme J. W. Ponder
GROMACS @GMX_TWEET
6K Followers 3K Following Fast, flexible, and free classical molecular dynamics simulation code. Powered by C++17, CUDA, OpenCL, SYCL, and OpenMP. Global community open-source project!
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YZi Labs @yzilabs
735K Followers 356 Following YZi Labs invests in ventures at every stage, prioritizing those with solid fundamentals in Web3, AI, and biotech.
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622 Followers 775 Following Bioengineering PhD @Stanford - protein design and mammalian synthetic biology
Binance @binance
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Aster @Aster_DEX
236K Followers 87 Following The Next-Gen Perp DEX for All Traders Backed by @yzilabs https://t.co/EF7uEmCGFa
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151K Followers 37 Following Known as Mad Max for my unorthodox ideas and passion for adventure, my scientific interests range from artificial intelligence to the ultimate nature of reality
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Mechanic #FixTheFilte... @GrassFedBitcoin
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